MicroRNA-199a* regulates the expression of cyclooxygenase-2 in human chondrocytes.

PubWeight™: 1.14‹?› | Rank: Top 10%

🔗 View Article (PMC 4509731)

Published in Ann Rheum Dis on January 31, 2012

Authors

Nahid Akhtar1, Tariq M Haqqi

Author Affiliations

1: Department of Medicine/Rheumatology, MetroHealth Medical Center/Case Western Reserve University, Cleveland, Ohio 44109, USA.

Articles citing this

Noncoding RNAs: new players in chronic pain. Anesthesiology (2014) 0.99

Flexible and versatile as a chameleon-sophisticated functions of microRNA-199a. Int J Mol Sci (2012) 0.93

Osteoarthritis year in review 2013: biology. Osteoarthritis Cartilage (2013) 0.93

Deregulation and therapeutic potential of microRNAs in arthritic diseases. Nat Rev Rheumatol (2015) 0.91

The inflammatory circuitry of miR-149 as a pathological mechanism in osteoarthritis. Rheumatol Int (2013) 0.90

Chronic arsenic exposure and angiogenesis in human bronchial epithelial cells via the ROS/miR-199a-5p/HIF-1α/COX-2 pathway. Environ Health Perspect (2014) 0.90

MicroRNA-602 and microRNA-608 regulate sonic hedgehog expression via target sites in the coding region in human chondrocytes. Arthritis Rheumatol (2015) 0.89

MicroRNAs in cartilage development, homeostasis, and disease. Curr Osteoporos Rep (2014) 0.89

MiRNA-199a-3p regulates C2C12 myoblast differentiation through IGF-1/AKT/mTOR signal pathway. Int J Mol Sci (2013) 0.89

MiR-26a and miR-144 inhibit proliferation and metastasis of esophageal squamous cell cancer by inhibiting cyclooxygenase-2. Oncotarget (2016) 0.89

Prostaglandins are essential for cervical ripening in LPS-mediated preterm birth but not term or antiprogestin-driven preterm ripening. Endocrinology (2013) 0.85

Silencing of miR-101 Prevents Cartilage Degradation by Regulating Extracellular Matrix-related Genes in a Rat Model of Osteoarthritis. Mol Ther (2015) 0.82

Epigallocatechin-3-O-gallate up-regulates microRNA-199a-3p expression by down-regulating the expression of cyclooxygenase-2 in stimulated human osteoarthritis chondrocytes. J Cell Mol Med (2016) 0.82

MicroRNA in 2012: Biotherapeutic potential of microRNAs in rheumatic diseases. Nat Rev Rheumatol (2013) 0.81

Current Status and Strategy of microRNA Research for Cartilage Development and Osteoarthritis Pathogenesis. J Bone Metab (2016) 0.81

Acquiring chondrocyte phenotype from human mesenchymal stem cells under inflammatory conditions. Int J Mol Sci (2014) 0.80

Regulation of COX-2 expression by miR-146a in lung cancer cells. RNA (2014) 0.80

MicroRNAs' Involvement in Osteoarthritis and the Prospects for Treatments. Evid Based Complement Alternat Med (2015) 0.79

Cyclooxygenase-2 and microRNA-155 expression are elevated in asthmatic airway smooth muscle cells. Am J Respir Cell Mol Biol (2015) 0.79

The Role of MicroRNAs and Their Targets in Osteoarthritis. Curr Rheumatol Rep (2016) 0.79

Significance of epigenetic landscape in cartilage regeneration from the cartilage development and pathology perspective. Stem Cells Dev (2014) 0.78

Cyclooxygenase-2, a Potential Therapeutic Target, Is Regulated by miR-101 in Esophageal Squamous Cell Carcinoma. PLoS One (2015) 0.76

Mechanistic Role of MicroRNA in Cancer Chemoprevention by Nonsteroidal Anti-inflammatory Drugs. Curr Pharmacol Rep (2015) 0.75

Intra-articular Delivery of Antago-miR-483-5p Inhibits Osteoarthritis by Modulating Matrilin 3 and Tissue Inhibitor of Metalloproteinase 2. Mol Ther (2017) 0.75

Genomics of pain in osteoarthritis. Osteoarthritis Cartilage (2013) 0.75

Inflammation and epigenetic regulation in osteoarthritis. Connect Tissue Res (2016) 0.75

Computational functional genomics based analysis of pain-relevant micro-RNAs. Hum Genet (2015) 0.75

Role of MicroRNA in Osteoarthritis. J Arthritis (2017) 0.75

Effect of the interaction between MiR-200b-3p and DNMT3A on cartilage cells of osteoarthritis patients. J Cell Mol Med (2017) 0.75

Articles cited by this

Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell (2005) 96.87

Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association. Arthritis Rheum (1986) 29.12

Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part II. Arthritis Rheum (2008) 19.80

The American College of Rheumatology criteria for the classification and reporting of osteoarthritis of the hip. Arthritis Rheum (1991) 7.94

Cyclooxygenase in biology and disease. FASEB J (1998) 7.17

Altered expression of MicroRNA in synovial fibroblasts and synovial tissue in rheumatoid arthritis. Arthritis Rheum (2008) 4.08

MicroRNAs: novel regulators involved in the pathogenesis of psoriasis? PLoS One (2007) 3.96

MicroRNA-146A contributes to abnormal activation of the type I interferon pathway in human lupus by targeting the key signaling proteins. Arthritis Rheum (2009) 3.44

Expression of microRNA-146 in rheumatoid arthritis synovial tissue. Arthritis Rheum (2008) 3.35

Dicer-dependent pathways regulate chondrocyte proliferation and differentiation. Proc Natl Acad Sci U S A (2008) 3.10

MicroRNAs: novel biomarkers for human cancer. Clin Chem (2009) 2.97

Impaired inflammatory and pain responses in mice lacking an inducible prostaglandin E synthase. Proc Natl Acad Sci U S A (2003) 2.80

The cartilage specific microRNA-140 targets histone deacetylase 4 in mouse cells. FEBS Lett (2006) 2.79

MicroRNA-140 plays dual roles in both cartilage development and homeostasis. Genes Dev (2010) 2.70

Integrative microRNA and proteomic approaches identify novel osteoarthritis genes and their collaborative metabolic and inflammatory networks. PLoS One (2008) 2.65

Variations in the intrinsic mechanical properties of human articular cartilage with age, degeneration, and water content. J Bone Joint Surg Am (1982) 2.57

A role of miR-27 in the regulation of adipogenesis. FEBS J (2009) 2.27

Plasma and synovial fluid microRNAs as potential biomarkers of rheumatoid arthritis and osteoarthritis. Arthritis Res Ther (2010) 2.25

Cyclooxygenase-2 and prostaglandins in articular tissues. Semin Arthritis Rheum (2003) 2.22

MicroRNA regulation of cyclooxygenase-2 during embryo implantation. Proc Natl Acad Sci U S A (2007) 2.16

MiR-101 downregulation is involved in cyclooxygenase-2 overexpression in human colon cancer cells. Exp Cell Res (2008) 2.03

Microarray analysis of microRNA expression in peripheral blood cells of systemic lupus erythematosus patients. Lupus (2007) 2.03

MicroRNA-140 is expressed in differentiated human articular chondrocytes and modulates interleukin-1 responses. Arthritis Rheum (2009) 1.99

MicroRNA-124a is a key regulator of proliferation and monocyte chemoattractant protein 1 secretion in fibroblast-like synoviocytes from patients with rheumatoid arthritis. Arthritis Rheum (2009) 1.98

Adding fuel to fire: microRNAs as a new class of mediators of inflammation. Ann Rheum Dis (2008) 1.96

The interleukin 1beta pathway in the pathogenesis of osteoarthritis. J Rheumatol (2008) 1.90

Expression of MicroRNA-146a in osteoarthritis cartilage. Arthritis Rheum (2009) 1.84

The identification of differentially expressed microRNA in osteoarthritic tissue that modulate the production of TNF-alpha and MMP13. Osteoarthritis Cartilage (2008) 1.81

MicroRNA-27b regulates the expression of matrix metalloproteinase 13 in human osteoarthritis chondrocytes. Arthritis Rheum (2010) 1.78

MicroRNAs as a therapeutic target for cardiovascular diseases. J Cell Mol Med (2009) 1.67

Prostaglandin E(2) regulates the level and stability of cyclooxygenase-2 mRNA through activation of p38 mitogen-activated protein kinase in interleukin-1 beta-treated human synovial fibroblasts. J Biol Chem (2001) 1.54

Altered expression of microRNA-203 in rheumatoid arthritis synovial fibroblasts and its role in fibroblast activation. Arthritis Rheum (2011) 1.46

Regulation of the IGFBP-5 and MMP-13 genes by the microRNAs miR-140 and miR-27a in human osteoarthritic chondrocytes. BMC Musculoskelet Disord (2009) 1.40

MicroRNA-146a is linked to pain-related pathophysiology of osteoarthritis. Gene (2011) 1.38

Epigallocatechin-3-gallate inhibits interleukin-1beta-induced expression of nitric oxide synthase and production of nitric oxide in human chondrocytes: suppression of nuclear factor kappaB activation by degradation of the inhibitor of nuclear factor kappaB. Arthritis Rheum (2002) 1.29

Pathogenesis of arthritis: recent research progress. Nat Immunol (2001) 1.23

A microRNA, miR-101a, controls mammary gland development by regulating cyclooxygenase-2 expression. Differentiation (2008) 1.22

Advanced glycation end products induce the expression of interleukin-6 and interleukin-8 by receptor for advanced glycation end product-mediated activation of mitogen-activated protein kinases and nuclear factor-κB in human osteoarthritis chondrocytes. Rheumatology (Oxford) (2010) 1.19

Cytokine targeting in osteoarthritis. Curr Drug Targets (2007) 1.18

Up-regulation of microsomal prostaglandin E synthase 1 in osteoarthritic human cartilage: critical roles of the ERK-1/2 and p38 signaling pathways. Arthritis Rheum (2004) 1.16

A mini-review: microRNA in arthritis. Physiol Genomics (2011) 1.15

Bioavailable constituents/metabolites of pomegranate (Punica granatum L) preferentially inhibit COX2 activity ex vivo and IL-1beta-induced PGE2 production in human chondrocytes in vitro. J Inflamm (Lond) (2008) 1.14

Silencing microRNA-34a inhibits chondrocyte apoptosis in a rat osteoarthritis model in vitro. Rheumatology (Oxford) (2010) 1.13

The induction of cell death in human osteoarthritis chondrocytes by nitric oxide is related to the production of prostaglandin E2 via the induction of cyclooxygenase-2. J Immunol (2000) 1.11

p38/NF-kB-dependent expression of COX-2 during differentiation and inflammatory response of chondrocytes. J Cell Biochem (2008) 1.04

Differentiation regulates interleukin-1beta-induced cyclo-oxygenase-2 in human articular chondrocytes: role of p38 mitogen-activated protein kinase. Biochem J (2002) 1.02

Outcome of specific COX-2 inhibition in rheumatoid arthritis. J Rheumatol Suppl (1997) 0.99

Towards a molecular understanding of arthritis. Chem Biol (1999) 0.91

COX-2 selective inhibitors in the treatment of osteoarthritis. Semin Arthritis Rheum (2008) 0.90

MicroRNA and AU-rich element regulation of prostaglandin synthesis. Cancer Metastasis Rev (2011) 0.84

Articles by these authors

MicroRNA-27b regulates the expression of matrix metalloproteinase 13 in human osteoarthritis chondrocytes. Arthritis Rheum (2010) 1.78

Biological basis for the use of botanicals in osteoarthritis and rheumatoid arthritis: a review. Evid Based Complement Alternat Med (2005) 1.55

Pathophysiological mechanisms in osteoarthritis lead to novel therapeutic strategies. Cells Tissues Organs (2003) 1.51

Green tea polyphenol epigallocatechin-3-gallate inhibits the IL-1 beta-induced activity and expression of cyclooxygenase-2 and nitric oxide synthase-2 in human chondrocytes. Free Radic Biol Med (2002) 1.35

Punica granatum L. extract inhibits IL-1beta-induced expression of matrix metalloproteinases by inhibiting the activation of MAP kinases and NF-kappaB in human chondrocytes in vitro. J Nutr (2005) 1.31

Neutrophil gelatinase-associated lipocalin is expressed in osteoarthritis and forms a complex with matrix metalloproteinase 9. Arthritis Rheum (2007) 1.30

Immunopathogenesis of osteoarthritis. Clin Immunol (2013) 1.29

Epigallocatechin-3-gallate inhibits interleukin-1beta-induced expression of nitric oxide synthase and production of nitric oxide in human chondrocytes: suppression of nuclear factor kappaB activation by degradation of the inhibitor of nuclear factor kappaB. Arthritis Rheum (2002) 1.29

Green tea polyphenol epigallocatechin-3-gallate (EGCG) differentially inhibits interleukin-1 beta-induced expression of matrix metalloproteinase-1 and -13 in human chondrocytes. J Pharmacol Exp Ther (2003) 1.29

Consumption of hydrolyzable tannins-rich pomegranate extract suppresses inflammation and joint damage in rheumatoid arthritis. Nutrition (2008) 1.25

Advanced glycation end products induce the expression of interleukin-6 and interleukin-8 by receptor for advanced glycation end product-mediated activation of mitogen-activated protein kinases and nuclear factor-κB in human osteoarthritis chondrocytes. Rheumatology (Oxford) (2010) 1.19

Bioavailable constituents/metabolites of pomegranate (Punica granatum L) preferentially inhibit COX2 activity ex vivo and IL-1beta-induced PGE2 production in human chondrocytes in vitro. J Inflamm (Lond) (2008) 1.14

Polyphenol-rich pomegranate fruit extract (POMx) suppresses PMACI-induced expression of pro-inflammatory cytokines by inhibiting the activation of MAP Kinases and NF-kappaB in human KU812 cells. J Inflamm (Lond) (2009) 1.13

Green tea polyphenol epigallocatechin-3-gallate inhibits advanced glycation end product-induced expression of tumor necrosis factor-alpha and matrix metalloproteinase-13 in human chondrocytes. Arthritis Res Ther (2009) 1.13

Pomegranate extract inhibits the interleukin-1β-induced activation of MKK-3, p38α-MAPK and transcription factor RUNX-2 in human osteoarthritis chondrocytes. Arthritis Res Ther (2010) 1.10

Green tea polyphenol epigallocatechin-3-gallate: inflammation and arthritis. [corrected]. Life Sci (2010) 1.09

Epigallocatechin-3-gallate selectively inhibits interleukin-1beta-induced activation of mitogen activated protein kinase subgroup c-Jun N-terminal kinase in human osteoarthritis chondrocytes. J Orthop Res (2003) 1.08

Epigallocatechin-3-gallate suppresses the global interleukin-1beta-induced inflammatory response in human chondrocytes. Arthritis Res Ther (2011) 1.08

Hydrostatic pressure induces apoptosis in human chondrocytes from osteoarthritic cartilage through up-regulation of tumor necrosis factor-alpha, inducible nitric oxide synthase, p53, c-myc, and bax-alpha, and suppression of bcl-2. J Cell Biochem (2002) 1.06

Green tea polyphenols-induced apoptosis in human osteosarcoma SAOS-2 cells involves a caspase-dependent mechanism with downregulation of nuclear factor-kappaB. Toxicol Appl Pharmacol (2006) 1.00

Modulation of ten-eleven translocation 1 (TET1), Isocitrate Dehydrogenase (IDH) expression, α-Ketoglutarate (α-KG), and DNA hydroxymethylation levels by interleukin-1β in primary human chondrocytes. J Biol Chem (2014) 0.99

Delphinidin inhibits IL-1β-induced activation of NF-κB by modulating the phosphorylation of IRAK-1(Ser376) in human articular chondrocytes. Rheumatology (Oxford) (2013) 0.97

CD6: expression during development, apoptosis and selection of human and mouse thymocytes. Int Immunol (2002) 0.96

Current nutraceuticals in the management of osteoarthritis: a review. Ther Adv Musculoskelet Dis (2012) 0.94

Phenyl N-tert-butylnitrone down-regulates interleukin-1 beta-stimulated matrix metalloproteinase-13 gene expression in human chondrocytes: suppression of c-Jun NH2-terminal kinase, p38-mitogen-activated protein kinase and activating protein-1. J Pharmacol Exp Ther (2003) 0.93

Effect of a Herbal-Leucine mix on the IL-1β-induced cartilage degradation and inflammatory gene expression in human chondrocytes. BMC Complement Altern Med (2011) 0.90

MicroRNA-602 and microRNA-608 regulate sonic hedgehog expression via target sites in the coding region in human chondrocytes. Arthritis Rheumatol (2015) 0.89

Update on Targets of Biologic Therapies for Rheumatoid Arthritis. Curr Rheumatol Rev (2008) 0.89

Endoplasmic reticulum stress induces the expression of COX-2 through activation of eIF2α, p38-MAPK and NF-κB in advanced glycation end products stimulated human chondrocytes. Biochim Biophys Acta (2012) 0.89

Butrin, isobutrin, and butein from medicinal plant Butea monosperma selectively inhibit nuclear factor-kappaB in activated human mast cells: suppression of tumor necrosis factor-alpha, interleukin (IL)-6, and IL-8. J Pharmacol Exp Ther (2010) 0.88

Genomic structure and functional characterization of the promoter region of human IkappaB kinase-related kinase IKKi/IKKvarepsilon gene. Gene (2005) 0.87

Expression and characterization of a novel CD6 ligand in cells derived from joint and epithelial tissues. J Immunol (2004) 0.84

The chrondoprotective actions of a natural product are associated with the activation of IGF-1 production by human chondrocytes despite the presence of IL-1beta. BMC Complement Altern Med (2006) 0.83

Chondroprotective effects of a proanthocyanidin rich Amazonian genonutrient reflects direct inhibition of matrix metalloproteinases and upregulation of IGF-1 production by human chondrocytes. J Inflamm (Lond) (2007) 0.83

Protective effects of C-type natriuretic peptide on linear growth and articular cartilage integrity in a mouse model of inflammatory arthritis. Arthritis Rheumatol (2014) 0.78