miR-21 promotes migration and invasion by the miR-21-PDCD4-AP-1 feedback loop in human hepatocellular carcinoma.

PubWeight™: 1.12‹?› | Rank: Top 10%

🔗 View Article (PMID 22322403)

Published in Oncol Rep on February 09, 2012

Authors

Qin Zhu1, Zhiming Wang, Yu Hu, Jindong Li, Xinying Li, Ledu Zhou, Yun Huang

Author Affiliations

1: Department of General Surgery, Xiangya Hospital, Central South University, Changsha, Hunan 410008, PR China.

Articles citing this

Pathogenic mechanisms in HBV- and HCV-associated hepatocellular carcinoma. Nat Rev Cancer (2013) 2.87

MicroRNAs in hepatocellular carcinoma: regulation, function, and clinical implications. ScientificWorldJournal (2013) 1.16

Regulation of cancer metastasis by cell-free miRNAs. Biochim Biophys Acta (2014) 1.02

MicroRNA-144 is regulated by activator protein-1 (AP-1) and decreases expression of Alzheimer disease-related a disintegrin and metalloprotease 10 (ADAM10). J Biol Chem (2013) 0.99

Epigenetics of hepatocellular carcinoma: role of microRNA. World J Gastroenterol (2013) 0.95

miRNAs affect the development of hepatocellular carcinoma via dysregulation of their biogenesis and expression. Cell Commun Signal (2014) 0.91

MicroRNA expression might predict prognosis of epithelial hepatoblastoma. Virchows Arch (2014) 0.90

MicroRNA-21 promotes hepatocellular carcinoma HepG2 cell proliferation through repression of mitogen-activated protein kinase-kinase 3. BMC Cancer (2013) 0.89

MicroRNAs in the Regulation of MMPs and Metastasis. Cancers (Basel) (2014) 0.88

Controlling RECK miR21 Promotes Tumor Cell Invasion and Is Related to Biochemical Recurrence in Prostate Cancer. J Cancer (2015) 0.87

Role of microRNA-mediated MMP regulation in the treatment and diagnosis of malignant tumors. Cancer Biol Ther (2013) 0.85

Clinical implications of microRNAs in liver cancer stem cells. Chin J Cancer (2013) 0.83

The critical roles of miR-21 in anti-cancer effects of curcumin. Ann Transl Med (2015) 0.83

microRNA Regulation and Its Consequences in Cancer. Curr Pathobiol Rep (2012) 0.82

Dehydroepiandrosterone Activation of G-protein-coupled Estrogen Receptor Rapidly Stimulates MicroRNA-21 Transcription in Human Hepatocellular Carcinoma Cells. J Biol Chem (2015) 0.81

Function and clinical potential of microRNAs in hepatocellular carcinoma. Oncol Lett (2015) 0.81

Feedback regulations of miR-21 and MAPKs via Pdcd4 and Spry1 are involved in arsenite-induced cell malignant transformation. PLoS One (2013) 0.81

Regulation of molecular pathways in ischemia-reperfusion injury after liver transplantation. Transplantation (2013) 0.80

Inhibition of NF-κB by deoxycholic acid induces miR-21/PDCD4-dependent hepatocelular apoptosis. Sci Rep (2015) 0.80

MiR-17-92 cluster promotes hepatocarcinogenesis. Carcinogenesis (2015) 0.80

Effect of microRNA-21 on the proliferation of human degenerated nucleus pulposus by targeting programmed cell death 4. Braz J Med Biol Res (2016) 0.79

Inferring the perturbed microRNA regulatory networks in cancer using hierarchical gene co-expression signatures. PLoS One (2013) 0.79

Selective inhibition of miR-21 by phage display screened peptide. Nucleic Acids Res (2015) 0.79

Circulating Plasma Levels of MicroRNA-21 and MicroRNA-221 Are Potential Diagnostic Markers for Primary Intrahepatic Cholangiocarcinoma. PLoS One (2016) 0.79

Differential MIR-21 expression in plasma from mesenteric versus peripheral veins: an observational study of disease-free survival in surgically resected colon cancer patients. Medicine (Baltimore) (2015) 0.78

Dehydroepiandrosterone-induces miR-21 transcription in HepG2 cells through estrogen receptor β and androgen receptor. Mol Cell Endocrinol (2014) 0.78

Relation between microRNAs and Apoptosis in Hepatocellular Carcinoma. Open Access Maced J Med Sci (2016) 0.77

The oncogenic microRNA OncomiR-21 overexpressed during Marek's disease lymphomagenesis is transactivated by the viral oncoprotein Meq. J Virol (2012) 0.77

Ultrasound-guided therapeutic modulation of hepatocellular carcinoma using complementary microRNAs. J Control Release (2016) 0.75

Role of microRNA-21 in radiosensitivity in non-small cell lung cancer cells by targeting PDCD4 gene. Oncotarget (2017) 0.75

Persistent distention of colon damages interstitial cells of Cajal through Ca(2+) -ERK-AP-1-miR-34c-SCF deregulation. J Cell Mol Med (2017) 0.75

MicroRNA-21 in Skin Fibrosis: Potential for Diagnosis and Treatment. Mol Diagn Ther (2017) 0.75

Low Levels of Microsatellite Instability at Simple Repeated Sequences Commonly Occur in Human Hepatocellular Carcinoma. Cancer Genomics Proteomics (2017) 0.75

Articles by these authors

Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2. Nature (2010) 8.87

Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells. Nature (2011) 7.43

Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells. Cell Stem Cell (2011) 7.41

Acrolein is a major cigarette-related lung cancer agent: Preferential binding at p53 mutational hotspots and inhibition of DNA repair. Proc Natl Acad Sci U S A (2006) 2.74

Mutational spectrum analysis of chronic myelomonocytic leukemia includes genes associated with epigenetic regulation: UTX, EZH2, and DNMT3A. Blood (2011) 2.47

ApiDB: integrated resources for the apicomplexan bioinformatics resource center. Nucleic Acids Res (2006) 2.37

Relationship between burnout and occupational stress among nurses in China. J Adv Nurs (2007) 2.26

STIM1 gates the store-operated calcium channel ORAI1 in vitro. Nat Struct Mol Biol (2009) 2.15

Podocyte-specific overexpression of the antioxidant metallothionein reduces diabetic nephropathy. J Am Soc Nephrol (2008) 1.94

Oocyte vitrification does not increase the risk of embryonic aneuploidy or diminish the implantation potential of blastocysts created after intracytoplasmic sperm injection: a novel, paired randomized controlled trial using DNA fingerprinting. Fertil Steril (2012) 1.83

Liquid phase production of graphene by exfoliation of graphite in surfactant/water solutions. J Am Chem Soc (2009) 1.77

Relationship of urinary bisphenol A concentration to risk for prevalent type 2 diabetes in Chinese adults: a cross-sectional analysis. Ann Intern Med (2011) 1.74

Cross-sectional and longitudinal association of serum alanine aminotransaminase and γ-glutamyltransferase with metabolic syndrome in middle-aged and elderly Chinese people. J Diabetes (2011) 1.71

Topological requirements and signaling properties of T cell-activating, anti-CD28 antibody superagonists. J Exp Med (2003) 1.70

Mutagenicity and sequence specificity of acrolein-DNA adducts. Chem Res Toxicol (2009) 1.65

Urinary bisphenol A (BPA) concentration associates with obesity and insulin resistance. J Clin Endocrinol Metab (2011) 1.63

Liver fat content is associated with increased carotid atherosclerosis in a Chinese middle-aged and elderly population: the Shanghai Changfeng study. Atherosclerosis (2012) 1.60

Origins of 1/f noise in nanostructure inclusion polymorphous silicon films. Nanoscale Res Lett (2011) 1.54

Nitric oxide suppresses NLRP3 inflammasome activation and protects against LPS-induced septic shock. Cell Res (2013) 1.54

Synthesis of chiral ionic liquids from natural amino acids. J Org Chem (2003) 1.47

The mTOR pathway is associated with the poor prognosis of human hepatocellular carcinoma. Med Oncol (2009) 1.46

Combined effects of 19 common variations on type 2 diabetes in Chinese: results from two community-based studies. PLoS One (2010) 1.43

Cardiac troponin testing in the acute care setting: ordering, reporting, and high sensitivity assays--an update from the Canadian society of clinical chemists (CSCC). Clin Biochem (2011) 1.41

Stage-specific roles for tet1 and tet2 in DNA demethylation in primordial germ cells. Cell Stem Cell (2013) 1.40

A standard approach to expose the recurrent laryngeal nerve during endoscopic thyroidectomy. J Laparoendosc Adv Surg Tech A (2012) 1.40

Elevated Th22 cells correlated with Th17 cells in patients with rheumatoid arthritis. J Clin Immunol (2011) 1.38

Association between MTR A2756G polymorphism and childhood acute lymphoblastic leukemia: a meta-analysis. Leuk Lymphoma (2013) 1.37

Field emission from in situ-grown vertically aligned SnO2 nanowire arrays. Nanoscale Res Lett (2012) 1.31

NF-kappaB-dependent microRNA-425 upregulation promotes gastric cancer cell growth by targeting PTEN upon IL-1β induction. Mol Cancer (2014) 1.27

miR-15a and miR-16 affect the angiogenesis of multiple myeloma by targeting VEGF. Carcinogenesis (2012) 1.24

Rapid large-scale preparation of ZnO nanowires for photocatalytic application. Nanoscale Res Lett (2011) 1.24

Association of arterial stiffness with HbA1c in 1,000 type 2 diabetic patients with or without hypertension. Endocrine (2009) 1.23

Negative regulation of Toll-like receptor signaling pathway. Microbes Infect (2009) 1.22

Design and application of a class of sensors to monitor Ca2+ dynamics in high Ca2+ concentration cellular compartments. Proc Natl Acad Sci U S A (2011) 1.20

Tetraploid cells from cytokinesis failure induce aneuploidy and spontaneous transformation of mouse ovarian surface epithelial cells. Cell Cycle (2012) 1.20

miR-124, miR-137 and miR-340 regulate colorectal cancer growth via inhibition of the Warburg effect. Oncol Rep (2012) 1.16

Bone marrow and the control of immunity. Cell Mol Immunol (2011) 1.15

A long non-coding RNA, PTCSC3, as a tumor suppressor and a target of miRNAs in thyroid cancer cells. Exp Ther Med (2013) 1.15

Developing sensors for real-time measurement of high Ca2+ concentrations. Biochemistry (2007) 1.14

Proteome analysis of human lung squamous carcinoma. Proteomics (2006) 1.12

Impact of network structure and cellular response on spike time correlations. PLoS Comput Biol (2012) 1.12

Identification of the calmodulin binding domain of connexin 43. J Biol Chem (2007) 1.11

Multiple origins of spontaneously arising micronuclei in HeLa cells: direct evidence from long-term live cell imaging. Mutat Res (2008) 1.10

Fluoroquinolone-resistant Streptococcus agalactiae: epidemiology and mechanism of resistance. Antimicrob Agents Chemother (2005) 1.09

A new Kv1.2 channelopathy underlying cerebellar ataxia. J Biol Chem (2010) 1.08

XIAP is related to the chemoresistance and inhibited its expression by RNA interference sensitize pancreatic carcinoma cells to chemotherapeutics. Pancreas (2006) 1.07

Receptor for activated C kinase 1 promotes hepatocellular carcinoma growth by enhancing mitogen-activated protein kinase kinase 7 activity. Hepatology (2013) 1.07

Effect of carcinogenic acrolein on DNA repair and mutagenic susceptibility. J Biol Chem (2012) 1.07

Printable cross-linked polymer blend dielectrics. Design strategies, synthesis, microstructures, and electrical properties, with organic field-effect transistors as testbeds. J Am Chem Soc (2008) 1.06

T cell Ig mucin-3 promotes homeostasis of sepsis by negatively regulating the TLR response. J Immunol (2013) 1.05

Overexpression of EphA2, MMP-9, and MVD-CD34 in hepatocellular carcinoma: Implications for tumor progression and prognosis. Hepatol Res (2009) 1.05

Zinc transporter-8 gene (SLC30A8) is associated with type 2 diabetes in Chinese. J Clin Endocrinol Metab (2008) 1.05

Serum uric acid associates with the incidence of type 2 diabetes in a prospective cohort of middle-aged and elderly Chinese. Endocrine (2011) 1.04

Serum fetuin-A associates with type 2 diabetes and insulin resistance in Chinese adults. PLoS One (2011) 1.02

Lethal action of quinolones against a temperature-sensitive dnaB replication mutant of Escherichia coli. Antimicrob Agents Chemother (2006) 1.02

General and controllable synthesis strategy of metal oxide/TiO2 hierarchical heterostructures with improved lithium-ion battery performance. Sci Rep (2012) 1.02

Lung cancer mortality from exposure to chrysotile asbestos and smoking: a case-control study within a cohort in China. Occup Environ Med (2010) 1.02

Reduced expression and novel splice variants of ING4 in human gastric adenocarcinoma. J Pathol (2009) 1.01

The GLIB technique for genome-wide mapping of 5-hydroxymethylcytosine. Nat Protoc (2012) 1.01

Common genetic risk factors for venous thrombosis in the Chinese population. Am J Hum Genet (2013) 1.01

miR-301a is a candidate oncogene that targets the homeobox gene Gax in human hepatocellular carcinoma. Dig Dis Sci (2012) 1.01

The evaluation of cognitive impairment and relevant factors in patients with chronic obstructive pulmonary disease. Respiration (2012) 1.01

Earlier onset of motor deficits in mice with double mutations in Dyt1 and Sgce. J Biochem (2010) 1.00

Resveratrol downregulates the constitutional activation of nuclear factor-kappaB in multiple myeloma cells, leading to suppression of proliferation and invasion, arrest of cell cycle, and induction of apoptosis. Cancer Genet Cytogenet (2006) 0.99

FVB mouse genotype confers susceptibility to OVE26 diabetic albuminuria. Am J Physiol Renal Physiol (2010) 0.99

A novel NF-kappaB binding site controls human granzyme B gene transcription. J Immunol (2006) 0.99

Norethindrone acetate (NA) and ethinyl estradiol (EE) related oxidative transformation products in stability samples of formulated drug product: synthesis of authentic references. Steroids (2002) 0.98

ATM and ATR: sensing DNA damage. World J Gastroenterol (2004) 0.98

Diversity through phosphine catalysis identifies octahydro-1,6-naphthyridin-4-ones as activators of endothelium-driven immunity. Proc Natl Acad Sci U S A (2011) 0.98

Tumor-derived GM-CSF promotes inflammatory colon carcinogenesis via stimulating epithelial release of VEGF. Cancer Res (2013) 0.97

Quantitative analysis of multiple methylated genes in plasma for the diagnosis and prognosis of hepatocellular carcinoma. Exp Mol Pathol (2011) 0.97

Acrolein induced DNA damage, mutagenicity and effect on DNA repair. Mol Nutr Food Res (2011) 0.97

NFAT3 is specifically required for TNF-alpha-induced cyclooxygenase-2 (COX-2) expression and transformation of Cl41 cells. J Cell Sci (2006) 0.97

Ordered array of single adatoms with remarkable thermal stability: Au/Fe3O4(001). Phys Rev Lett (2012) 0.97

Reversible transition between thermodynamically stable phases with low density of oxygen vacancies on the SrTiO3(110) surface. Phys Rev Lett (2011) 0.96

The Shanghai Changfeng Study: a community-based prospective cohort study of chronic diseases among middle-aged and elderly: objectives and design. Eur J Epidemiol (2010) 0.96

Oxygen radical functionalization of boron nitride nanosheets. J Am Chem Soc (2012) 0.95

Lyn and PECAM-1 function as interdependent inhibitors of platelet aggregation. Blood (2011) 0.95

Aplexone targets the HMG-CoA reductase pathway and differentially regulates arteriovenous angiogenesis. Development (2011) 0.95

Intronic non-CG DNA hydroxymethylation and alternative mRNA splicing in honey bees. BMC Genomics (2013) 0.94

Serum fetuin-A is correlated with metabolic syndrome in middle-aged and elderly Chinese. Atherosclerosis (2011) 0.94

Gemcitabine eliminates double minute chromosomes from human ovarian cancer cells. PLoS One (2013) 0.94

Left too early: the effects of age at separation from parents on Chinese rural children's symptoms of anxiety and depression. Am J Public Health (2009) 0.94

CD147 expression as a significant prognostic factor in differentiated thyroid carcinoma. Transl Res (2008) 0.94

Suppression of allergic airway inflammation in a mouse model of asthma by exogenous mesenchymal stem cells. Exp Biol Med (Maywood) (2011) 0.93

Whole-genome sequences of four Mycobacterium bovis BCG vaccine strains. J Bacteriol (2011) 0.93

Phosphorylation of tau by death-associated protein kinase 1 antagonizes the kinase-induced cell apoptosis. J Alzheimers Dis (2013) 0.93

P68 RNA helicase is a nucleocytoplasmic shuttling protein. Cell Res (2009) 0.93

Inhibitors of phosphatidylinositol 3'-kinases promote mitotic cell death in HeLa cells. PLoS One (2012) 0.93

Impaired lung function is associated with increased carotid intima-media thickness in middle-aged and elderly Chinese. PLoS One (2013) 0.92

Work ability of workers in western China: reference data. Occup Med (Lond) (2005) 0.92

Genetic background analysis of protein C deficiency demonstrates a recurrent mutation associated with venous thrombosis in Chinese population. PLoS One (2012) 0.92

miRNA expression in breast cancer varies with lymph node metastasis and other clinicopathologic features. IUBMB Life (2014) 0.92

Quantitative methylation analysis of multiple genes using methylation-sensitive restriction enzyme-based quantitative PCR for the detection of hepatocellular carcinoma. Exp Mol Pathol (2011) 0.91

Blockade of complement activation product C5a activity using specific antibody attenuates intestinal damage in trinitrobenzene sulfonic acid induced model of colitis. Lab Invest (2010) 0.91

Effect of chloramphenicol, erythromycin, moxifloxacin, penicillin and tetracycline concentration on the recovery of resistant mutants of Mycobacterium smegmatis and Staphylococcus aureus. J Antimicrob Chemother (2003) 0.91

High-mobility group box 1 is associated with clinicopathologic features in patients with hepatocellular carcinoma. Pathol Oncol Res (2011) 0.91