Published in Nat Commun on February 21, 2012
Targeting IL-17 and TH17 cells in chronic inflammation. Nat Rev Drug Discov (2012) 4.70
Th17 cells in immunity to Candida albicans. Cell Host Microbe (2012) 1.97
Recent insights into Candida albicans biofilm resistance mechanisms. Curr Genet (2013) 1.20
The potential impact of antifungal drug resistance mechanisms on the host immune response to Candida. Virulence (2012) 1.03
Fungal allergy in asthma-state of the art and research needs. Clin Transl Allergy (2014) 1.03
Development of vaccines for Candida albicans: fighting a skilled transformer. Nat Rev Microbiol (2013) 0.98
IL-22 and IDO1 affect immunity and tolerance to murine and human vaginal candidiasis. PLoS Pathog (2013) 0.96
IL-17-mediated antifungal defense in the oral mucosa is independent of neutrophils. Mucosal Immunol (2014) 0.96
Therapeutic potential of targeting IL-17. Nat Immunol (2012) 0.95
Adaptive immune responses to Candida albicans infection. Virulence (2015) 0.92
DAMP signaling in fungal infections and diseases. Front Immunol (2012) 0.90
Pathogenic fungi regulate immunity by inducing neutrophilic myeloid-derived suppressor cells. Cell Host Microbe (2015) 0.88
Immunity and tolerance to fungi in hematopoietic transplantation: principles and perspectives. Front Immunol (2012) 0.86
Learning from other diseases: protection and pathology in chronic fungal infections. Semin Immunopathol (2015) 0.84
Antifungal Th Immunity: Growing up in Family. Front Immunol (2014) 0.83
The cross-talk between opportunistic fungi and the mammalian host via microbiota's metabolism. Semin Immunopathol (2014) 0.81
Adaptive immunity to fungi. Cold Spring Harb Perspect Med (2014) 0.80
Anti-Immune Strategies of Pathogenic Fungi. Front Cell Infect Microbiol (2016) 0.79
Distinct stages during colonization of the mouse gastrointestinal tract by Candida albicans. Front Microbiol (2015) 0.78
IL-17A in human respiratory diseases: innate or adaptive immunity? Clinical implications. Clin Dev Immunol (2013) 0.78
Fungal cell wall dynamics and infection site microenvironments: signal integration and infection outcome. Curr Opin Microbiol (2013) 0.77
IL-26: An Emerging Proinflammatory Member of the IL-10 Cytokine Family with Multifaceted Actions in Antiviral, Antimicrobial, and Autoimmune Responses. PLoS Pathog (2016) 0.76
Differential Regulation of Myeloid-Derived Suppressor Cells by Candida Species. Front Microbiol (2016) 0.75
A Candida albicans Strain Expressing Mammalian Interleukin-17A Results in Early Control of Fungal Growth during Disseminated Infection. Infect Immun (2015) 0.75
Albumin Enhances Caspofungin Activity against Aspergillus Species by Facilitating Drug Delivery to Germinating Hyphae. Antimicrob Agents Chemother (2015) 0.75
Validation of Reference Genes for Robust qRT-PCR Gene Expression Analysis in the Rice Blast Fungus Magnaporthe oryzae. PLoS One (2016) 0.75
Aspergillus fumigatus morphology and dynamic host interactions. Nat Rev Microbiol (2017) 0.75
The intraspecies diversity of C. albicans triggers qualitatively and temporally distinct host responses that determine the balance between commensalism and pathogenicity. Mucosal Immunol (2017) 0.75
Autophagy in health and disease: a double-edged sword. Science (2004) 13.69
Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages. Cell (2004) 12.71
Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae. J Cell Biol (2001) 7.68
Requirement of interleukin-17A for systemic anti-Candida albicans host defense in mice. J Infect Dis (2004) 6.54
Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity. Science (2011) 6.19
Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis. J Exp Med (2009) 5.55
Adhesive and mammalian transglutaminase substrate properties of Candida albicans Hwp1. Science (1999) 4.00
Autophagy enhances the efficacy of BCG vaccine by increasing peptide presentation in mouse dendritic cells. Nat Med (2009) 3.17
Surface hydrophobin prevents immune recognition of airborne fungal spores. Nature (2009) 3.07
Regulatory networks controlling Candida albicans morphogenesis. Trends Microbiol (1999) 3.06
Recognition of host immune activation by Pseudomonas aeruginosa. Science (2005) 2.84
Bacterial peptidoglycan triggers Candida albicans hyphal growth by directly activating the adenylyl cyclase Cyr1p. Cell Host Microbe (2008) 2.68
Sensing the environment: lessons from fungi. Nat Rev Microbiol (2007) 2.10
Ric1p and Rgp1p form a complex that catalyses nucleotide exchange on Ypt6p. EMBO J (2000) 2.04
Our current understanding of fungal biofilms. Crit Rev Microbiol (2009) 1.79
IL-22 defines a novel immune pathway of antifungal resistance. Mucosal Immunol (2010) 1.76
Candida morphogenesis and host-pathogen interactions. Curr Opin Microbiol (2004) 1.68
Control of immune response by amino acid metabolism. Immunol Rev (2010) 1.63
Expression of a chromosomally integrated, single-copy GFP gene in Candida albicans, and its use as a reporter of gene regulation. Mol Gen Genet (1998) 1.61
Signalling and oxidant adaptation in Candida albicans and Aspergillus fumigatus. Nat Rev Microbiol (2006) 1.56
Infection-related gene expression in Candida albicans. Curr Opin Microbiol (2007) 1.50
PI3K signaling of autophagy is required for starvation tolerance and virulenceof Cryptococcus neoformans. J Clin Invest (2008) 1.45
The protein kinase Tor1 regulates adhesin gene expression in Candida albicans. PLoS Pathog (2009) 1.44
Epithelial cell-derived S100 calcium-binding proteins as key mediators in the hallmark acute neutrophil response during Candida vaginitis. Infect Immun (2010) 1.38
Genome-wide analysis of Candida albicans gene expression patterns during infection of the mammalian kidney. Fungal Genet Biol (2008) 1.37
Autophagy in filamentous fungi. Fungal Genet Biol (2008) 1.28
A novel family of cell wall-related proteins regulated differently during the yeast life cycle. Mol Cell Biol (2000) 1.26
The CRH family coding for cell wall glycosylphosphatidylinositol proteins with a predicted transglycosidase domain affects cell wall organization and virulence of Candida albicans. J Biol Chem (2006) 1.20
Hypoxic conditions and iron restriction affect the cell-wall proteome of Candida albicans grown under vagina-simulative conditions. Microbiology (2008) 1.19
Prostaglandin E2 enhances and gamma interferon inhibits germ tube formation in Candida albicans. Infect Immun (1990) 1.17
Healthy human T-Cell Responses to Aspergillus fumigatus antigens. PLoS One (2010) 1.14
Autophagy in the pathogen Candida albicans. Microbiology (2007) 1.10
Expression and characterization of the flocculin Flo11/Muc1, a Saccharomyces cerevisiae mannoprotein with homotypic properties of adhesion. Eukaryot Cell (2007) 1.02
A role for antibodies in the generation of memory antifungal immunity. Eur J Immunol (2003) 0.97
The effects of growth hormone therapy on spontaneous sexual development. Horm Res (1992) 0.96
Intestinal microbiota, evolution of the immune system and the bad reputation of pro-inflammatory immunity. Cell Microbiol (2011) 0.93
Conservation, duplication, and loss of the Tor signaling pathway in the fungal kingdom. BMC Genomics (2010) 0.91
The GPI-anchored Gas and Crh families are fungal antigens. Yeast (2007) 0.89
Fungal antigens expressed during invasive aspergillosis. Infect Immun (2005) 0.87
Signaling cascades as drug targets in model and pathogenic fungi. Curr Opin Investig Drugs (2008) 0.86
The diverse roles of autophagy in medically important fungi. Autophagy (2008) 0.85
Candida albicans mutants in the BNI4 gene have reduced cell-wall chitin and alterations in morphogenesis. Microbiology (2004) 0.81
On the relation between citrate and calcium in normal and stone-former subjects. Int Urol Nephrol (1989) 0.80
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy (2007) 20.92
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus. Nature (2005) 8.55
CTLA-4-Ig regulates tryptophan catabolism in vivo. Nat Immunol (2002) 6.94
Epidermal growth factor receptor (EGFR) signaling in cancer. Gene (2005) 6.04
Modulation of tryptophan catabolism by regulatory T cells. Nat Immunol (2003) 5.47
IL-23 and the Th17 pathway promote inflammation and impair antifungal immune resistance. Eur J Immunol (2007) 4.54
Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease. Nature (2008) 4.28
The combined effects of tryptophan starvation and tryptophan catabolites down-regulate T cell receptor zeta-chain and induce a regulatory phenotype in naive T cells. J Immunol (2006) 3.84
The contribution of the Toll-like/IL-1 receptor superfamily to innate and adaptive immunity to fungal pathogens in vivo. J Immunol (2004) 3.21
Percutaneous dilatational tracheostomy with a double-lumen endotracheal tube: a comparison of feasibility, gas exchange, and airway pressures. Chest (2015) 3.20
Tolerance, DCs and tryptophan: much ado about IDO. Trends Immunol (2003) 3.18
Genetic PTX3 deficiency and aspergillosis in stem-cell transplantation. N Engl J Med (2014) 3.08
Surface hydrophobin prevents immune recognition of airborne fungal spores. Nature (2009) 3.07
A human-curated annotation of the Candida albicans genome. PLoS Genet (2005) 3.04
Non-redundant role of the long pentraxin PTX3 in anti-fungal innate immune response. Nature (2002) 3.01
CD28 induces immunostimulatory signals in dendritic cells via CD80 and CD86. Nat Immunol (2004) 2.90
IL-1 receptor blockade restores autophagy and reduces inflammation in chronic granulomatous disease in mice and in humans. Proc Natl Acad Sci U S A (2014) 2.86
Tryptophan catabolites from microbiota engage aryl hydrocarbon receptor and balance mucosal reactivity via interleukin-22. Immunity (2013) 2.78
Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells. Nat Immunol (2011) 2.76
The humoral pattern recognition receptor PTX3 is stored in neutrophil granules and localizes in extracellular traps. J Exp Med (2007) 2.71
IL-23 and Th17 cells enhance Th2-cell-mediated eosinophilic airway inflammation in mice. Am J Respir Crit Care Med (2008) 2.62
TAC1, transcriptional activator of CDR genes, is a new transcription factor involved in the regulation of Candida albicans ABC transporters CDR1 and CDR2. Eukaryot Cell (2004) 2.61
A mutation in Tac1p, a transcription factor regulating CDR1 and CDR2, is coupled with loss of heterozygosity at chromosome 5 to mediate antifungal resistance in Candida albicans. Genetics (2006) 2.54
Implications for KRAS status and EGFR-targeted therapies in metastatic CRC. Nat Rev Clin Oncol (2009) 2.48
Dendritic cells transport conidia and hyphae of Aspergillus fumigatus from the airways to the draining lymph nodes and initiate disparate Th responses to the fungus. J Immunol (2002) 2.35
IL-23 and IL-12 have overlapping, but distinct, effects on murine dendritic cells. J Immunol (2002) 2.32
The C-type lectin DC-SIGN (CD209) is an antigen-uptake receptor for Candida albicans on dendritic cells. Eur J Immunol (2003) 2.30
Genotypic evolution of azole resistance mechanisms in sequential Candida albicans isolates. Eukaryot Cell (2007) 2.25
A common drug-responsive element mediates the upregulation of the Candida albicans ABC transporters CDR1 and CDR2, two genes involved in antifungal drug resistance. Mol Microbiol (2002) 2.14
Metabotropic glutamate receptor-4 modulates adaptive immunity and restrains neuroinflammation. Nat Med (2010) 2.10
Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy. Nat Med (2007) 2.08
The global transcriptional response to transient cell wall damage in Saccharomyces cerevisiae and its regulation by the cell integrity signaling pathway. J Biol Chem (2004) 1.99
Genome-wide analysis of the response to cell wall mutations in the yeast Saccharomyces cerevisiae. J Biol Chem (2003) 1.99
Comparison of gene expression profiles of Candida albicans azole-resistant clinical isolates and laboratory strains exposed to drugs inducing multidrug transporters. Antimicrob Agents Chemother (2004) 1.86
Fungi, dendritic cells and receptors: a host perspective of fungal virulence. Trends Microbiol (2002) 1.83
TLRs govern neutrophil activity in aspergillosis. J Immunol (2004) 1.83
Candida albicans hyphal formation and the expression of the Efg1-regulated proteinases Sap4 to Sap6 are required for the invasion of parenchymal organs. Infect Immun (2002) 1.82
Mechanisms of endocrine resistance and novel therapeutic strategies in breast cancer. Endocr Relat Cancer (2005) 1.81
Gain of function mutations in CgPDR1 of Candida glabrata not only mediate antifungal resistance but also enhance virulence. PLoS Pathog (2009) 1.76
Reversion of a fungal genetic code alteration links proteome instability with genomic and phenotypic diversification. Proc Natl Acad Sci U S A (2013) 1.75
CRZ1, a target of the calcineurin pathway in Candida albicans. Mol Microbiol (2006) 1.74
CD80+Gr-1+ myeloid cells inhibit development of antifungal Th1 immunity in mice with candidiasis. J Immunol (2002) 1.73
Murine plasmacytoid dendritic cells initiate the immunosuppressive pathway of tryptophan catabolism in response to CD200 receptor engagement. J Immunol (2004) 1.69
B7/CD28-dependent CD4+CD25+ regulatory T cells are essential components of the memory-protective immunity to Candida albicans. J Immunol (2002) 1.69
Functional expression of indoleamine 2,3-dioxygenase by murine CD8 alpha(+) dendritic cells. Int Immunol (2002) 1.69
Protective tolerance to fungi: the role of IL-10 and tryptophan catabolism. Trends Microbiol (2006) 1.68
PTX3 plays a key role in the organization of the cumulus oophorus extracellular matrix and in in vivo fertilization. Development (2004) 1.68
Functional yet balanced reactivity to Candida albicans requires TRIF, MyD88, and IDO-dependent inhibition of Rorc. J Immunol (2007) 1.66
Increased expression of a novel Aspergillus fumigatus ABC transporter gene, atrF, in the presence of itraconazole in an itraconazole resistant clinical isolate. Fungal Genet Biol (2002) 1.66
A defect in tryptophan catabolism impairs tolerance in nonobese diabetic mice. J Exp Med (2003) 1.62
SOCS3 drives proteasomal degradation of indoleamine 2,3-dioxygenase (IDO) and antagonizes IDO-dependent tolerogenesis. Proc Natl Acad Sci U S A (2008) 1.58
Toward the identification of a tolerogenic signature in IDO-competent dendritic cells. Blood (2005) 1.56
Transferring functional immune responses to pathogens after haploidentical hematopoietic transplantation. Blood (2005) 1.54
Cripto-1 activates nodal- and ALK4-dependent and -independent signaling pathways in mammary epithelial Cells. Mol Cell Biol (2002) 1.53
The high osmotic response and cell wall integrity pathways cooperate to regulate transcriptional responses to zymolyase-induced cell wall stress in Saccharomyces cerevisiae. J Biol Chem (2009) 1.46
Hypoxia promotes danger-mediated inflammation via receptor for advanced glycation end products in cystic fibrosis. Am J Respir Crit Care Med (2013) 1.45
The sequential activation of the yeast HOG and SLT2 pathways is required for cell survival to cell wall stress. Mol Biol Cell (2008) 1.45
MARQ: an online tool to mine GEO for experiments with similar or opposite gene expression signatures. Nucleic Acids Res (2010) 1.45
A dendritic cell vaccine against invasive aspergillosis in allogeneic hematopoietic transplantation. Blood (2003) 1.45
Cutting edge: Autocrine TGF-beta sustains default tolerogenesis by IDO-competent dendritic cells. J Immunol (2008) 1.43
T cell apoptosis by kynurenines. Adv Exp Med Biol (2003) 1.43
A parasitic phase-specific adhesin of Coccidioides immitis contributes to the virulence of this respiratory Fungal pathogen. Infect Immun (2002) 1.43
End-of-life: still an Italian dilemma. Intensive Care Med (2008) 1.41
IL-17 and therapeutic kynurenines in pathogenic inflammation to fungi. J Immunol (2008) 1.40
TGF-beta and kynurenines as the key to infectious tolerance. Trends Mol Med (2009) 1.39
Antiviral activity of the long chain pentraxin PTX3 against influenza viruses. J Immunol (2008) 1.39
Genetic dissection of azole resistance mechanisms in Candida albicans and their validation in a mouse model of disseminated infection. Antimicrob Agents Chemother (2010) 1.39
Indoleamine 2,3-dioxygenase in infection: the paradox of an evasive strategy that benefits the host. Microbes Infect (2008) 1.39
Kynurenine pathway enzymes in dendritic cells initiate tolerogenesis in the absence of functional IDO. J Immunol (2006) 1.38
Immunity and tolerance to Aspergillus involve functionally distinct regulatory T cells and tryptophan catabolism. J Immunol (2006) 1.38
The MEK/MAPK pathway is involved in the resistance of breast cancer cells to the EGFR tyrosine kinase inhibitor gefitinib. J Cell Physiol (2006) 1.37
Anti-Aspergillus fumigatus efficacy of pentraxin 3 alone and in combination with antifungals. Antimicrob Agents Chemother (2004) 1.36
Indoleamine 2,3-dioxygenase: from catalyst to signaling function. Eur J Immunol (2012) 1.35
Crh1p and Crh2p are required for the cross-linking of chitin to beta(1-6)glucan in the Saccharomyces cerevisiae cell wall. Mol Microbiol (2007) 1.34
Lack of Toll IL-1R8 exacerbates Th17 cell responses in fungal infection. J Immunol (2008) 1.33
Vaccination of mice against invasive aspergillosis with recombinant Aspergillus proteins and CpG oligodeoxynucleotides as adjuvants. Microbes Infect (2002) 1.30
Functional plasticity of dendritic cell subsets as mediated by CD40 versus B7 activation. J Immunol (2003) 1.29
Th17/Treg imbalance in murine cystic fibrosis is linked to indoleamine 2,3-dioxygenase deficiency but corrected by kynurenines. Am J Respir Crit Care Med (2013) 1.28