Published in Sci Rep on August 03, 2011
DoriC 5.0: an updated database of oriC regions in both bacterial and archaeal genomes. Nucleic Acids Res (2012) 1.59
Comparative genomics analysis of Mycobacterium ulcerans for the identification of putative essential genes and therapeutic candidates. PLoS One (2012) 0.95
Geptop: a gene essentiality prediction tool for sequenced bacterial genomes based on orthology and phylogeny. PLoS One (2013) 0.95
Recent Advances in the Identification of Replication Origins Based on the Z-curve Method. Curr Genomics (2014) 0.94
IFIM: a database of integrated fitness information for microbial genes. Database (Oxford) (2014) 0.84
Genes found essential in other mycoplasmas are dispensable in Mycoplasma bovis. PLoS One (2014) 0.84
Evolutionary conservation analysis between the essential and nonessential genes in bacterial genomes. Sci Rep (2015) 0.79
Protein localization analysis of essential genes in prokaryotes. Sci Rep (2014) 0.78
Bacterial genome engineering and synthetic biology: combating pathogens. BMC Microbiol (2016) 0.76
The COG database: an updated version includes eukaryotes. BMC Bioinformatics (2003) 60.98
KEGG: Kyoto Encyclopedia of Genes and Genomes. Nucleic Acids Res (1999) 40.62
BLAST+: architecture and applications. BMC Bioinformatics (2009) 36.53
Essential Bacillus subtilis genes. Proc Natl Acad Sci U S A (2003) 14.01
Creation of a bacterial cell controlled by a chemically synthesized genome. Science (2010) 13.45
Global transposon mutagenesis and a minimal Mycoplasma genome. Science (1999) 11.36
Essential genes of a minimal bacterium. Proc Natl Acad Sci U S A (2006) 6.31
Identification of critical staphylococcal genes using conditional phenotypes generated by antisense RNA. Science (2001) 5.40
A genome-wide strategy for the identification of essential genes in Staphylococcus aureus. Mol Microbiol (2002) 4.26
Comparative genomics, minimal gene-sets and the last universal common ancestor. Nat Rev Microbiol (2003) 3.59
DEG 5.0, a database of essential genes in both prokaryotes and eukaryotes. Nucleic Acids Res (2008) 2.94
Ribonucleases J1 and J2: two novel endoribonucleases in B.subtilis with functional homology to E.coli RNase E. Nucleic Acids Res (2005) 2.74
How many genes can make a cell: the minimal-gene-set concept. Annu Rev Genomics Hum Genet (2000) 2.63
DEG: a database of essential genes. Nucleic Acids Res (2004) 2.42
Essentiality, not expressiveness, drives gene-strand bias in bacteria. Nat Genet (2003) 2.24
Essential genes on metabolic maps. Curr Opin Biotechnol (2006) 2.18
Large-scale transposon mutagenesis of Mycoplasma pulmonis. Mol Microbiol (2008) 2.08
An estimation of minimal genome size required for life. FEBS Lett (1995) 1.79
DoriC: a database of oriC regions in bacterial genomes. Bioinformatics (2007) 1.74
A novel genomics approach for the identification of drug targets in pathogens, with special reference to Pseudomonas aeruginosa. In Silico Biol (2004) 1.62
Towards the identification of essential genes using targeted genome sequencing and comparative analysis. BMC Genomics (2006) 1.39
Predicting essential genes in fungal genomes. Genome Res (2006) 1.34
Understanding protein dispensability through machine-learning analysis of high-throughput data. Bioinformatics (2004) 1.24
Computational prediction of essential genes in an unculturable endosymbiotic bacterium, Wolbachia of Brugia malayi. BMC Microbiol (2009) 1.22
Investigating the predictability of essential genes across distantly related organisms using an integrative approach. Nucleic Acids Res (2010) 1.21
Parts, property and sharing. Nat Biotechnol (2009) 1.19
Genomics. Synthetic genome brings new life to bacterium. Science (2010) 1.18
In silico identification of candidate drug and vaccine targets from various pathways in Neisseria gonorrhoeae. In Silico Biol (2009) 1.17
In silico identification of potential therapeutic targets in the human pathogen Helicobacter pylori. In Silico Biol (2006) 1.17
In silico analysis of Burkholderia pseudomallei genome sequence for potential drug targets. In Silico Biol (2006) 1.11
In silico prediction of yeast deletion phenotypes. Genet Mol Res (2006) 1.01
Identifying essential genes in bacterial metabolic networks with machine learning methods. BMC Syst Biol (2010) 1.01
In silico identification of putative drug targets from different metabolic pathways of Aeromonas hydrophila. In Silico Biol (2008) 1.00
Functionality of essential genes drives gene strand-bias in bacterial genomes. Biochem Biophys Res Commun (2010) 1.00
Predicting conserved essential genes in bacteria: in silico identification of putative drug targets. Mol Biosyst (2010) 0.90
Genomic Target Database (GTD): a database of potential targets in human pathogenic bacteria. Bioinformation (2009) 0.85
Unbottling the genes. Nat Biotechnol (2009) 0.77
Functionality of essential genes drives gene strand-bias in bacterial genomes. Biochem Biophys Res Commun (2010) 1.00
Enzymes are enriched in bacterial essential genes. PLoS One (2011) 0.85
Evolutionary conservation analysis between the essential and nonessential genes in bacterial genomes. Sci Rep (2015) 0.79
Recognition of Protein-coding Genes Based on Z-curve Algorithms. Curr Genomics (2014) 0.78
RNA-DNA differences are rarer in proto-oncogenes than in tumor suppressor genes. Sci Rep (2012) 0.75