Published in Exp Hematol on February 23, 2012
Increased μ-Calpain Activity in Blasts of Common B-Precursor Childhood Acute Lymphoblastic Leukemia Correlates with Their Lower Susceptibility to Apoptosis. PLoS One (2015) 1.39
Preventing the autophagic survival response by inhibition of calpain enhances the cytotoxic activity of bortezomib in vitro and in vivo. Cancer Chemother Pharmacol (2013) 0.92
Stress-induced cleavage of Myc promotes cancer cell survival. Genes Dev (2014) 0.87
Altered somatic hypermutation and reduced class-switch recombination in exonuclease 1-mutant mice. Nat Immunol (2004) 2.16
Acquisition of a multifunctional IgA+ plasma cell phenotype in the gut. Nature (2011) 2.04
Detection of chromatin-associated single-stranded DNA in regions targeted for somatic hypermutation. J Exp Med (2007) 1.46
Methylation protects cytidines from AID-mediated deamination. Mol Immunol (2005) 1.46
Examination of Msh6- and Msh3-deficient mice in class switching reveals overlapping and distinct roles of MutS homologues in antibody diversification. J Exp Med (2004) 1.41
Anti-tumor immunity in a model of acute myeloid leukemia. Leuk Lymphoma (2009) 1.39
Induction of somatic hypermutation is associated with modifications in immunoglobulin variable region chromatin. Immunity (2003) 1.35
AID constrains germinal center size by rendering B cells susceptible to apoptosis. Blood (2009) 1.33
The RNF8/RNF168 ubiquitin ligase cascade facilitates class switch recombination. Proc Natl Acad Sci U S A (2009) 1.24
Tumorigenesis: Twist1 links EMT to self-renewal. Nat Cell Biol (2010) 1.17
AID associates with single-stranded DNA with high affinity and a long complex half-life in a sequence-independent manner. Mol Cell Biol (2006) 1.09
Investigations into the regulation and function of the SH2 domain-containing protein-tyrosine phosphatase, SHP-1. Immunol Res (2006) 1.08
Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. J Biol Chem (2002) 1.07
Inhibition of Ca2+ influx is required for mitochondrial reactive oxygen species-induced endoplasmic reticulum Ca2+ depletion and cell death in leukemia cells. Mol Pharmacol (2006) 1.03
Single-stranded DNA structure and positional context of the target cytidine determine the enzymatic efficiency of AID. Mol Cell Biol (2007) 1.01
TNFα modulates protein degradation pathways in rheumatoid arthritis synovial fibroblasts. Arthritis Res Ther (2012) 1.01
X-ray crystal structure of the C4d fragment of human complement component C4. J Mol Biol (2002) 1.01
Cutting edge: the G-U mismatch glycosylase methyl-CpG binding domain 4 is dispensable for somatic hypermutation and class switch recombination. J Immunol (2003) 0.99
The mutation spectrum of purified AID is similar to the mutability index in Ramos cells and in ung(-/-)msh2(-/-) mice. Immunogenetics (2005) 0.98
Natural capsaicinoids improve swallow response in older patients with oropharyngeal dysphagia. Gut (2012) 0.98
Negative supercoiling creates single-stranded patches of DNA that are substrates for AID-mediated mutagenesis. PLoS Genet (2012) 0.94
Molecular mechanisms underlying SHP-1 gene expression. Eur J Biochem (2002) 0.94
NHEJ-deficient DT40 cells have increased levels of immunoglobulin gene conversion: evidence for a double strand break intermediate. Nucleic Acids Res (2006) 0.89
The concerted action of Msh2 and UNG stimulates somatic hypermutation at A . T base pairs. Mol Cell Biol (2009) 0.88
AID mutates a non-immunoglobulin transgene independent of chromosomal position. Mol Immunol (2006) 0.88
Sensitivity of myeloid leukemia cells to calcium influx blockade: application to bone marrow purging. Exp Hematol (2002) 0.84
The biochemistry of activation-induced deaminase and its physiological functions. Semin Immunol (2012) 0.84
Differences in the enzymatic efficiency of human and bony fish AID are mediated by a single residue in the C terminus modulating single-stranded DNA binding. FASEB J (2011) 0.83
Regulation of calpain activity by c-Myc through calpastatin and promotion of transformation in c-Myc-negative cells by calpastatin suppression. J Biol Chem (2008) 0.83
Msh2-dependent DNA repair mitigates a unique susceptibility of B cell progenitors to c-Myc-induced lymphomas. Proc Natl Acad Sci U S A (2009) 0.83
Ketotifen reverses MDR1-mediated multidrug resistance in human breast cancer cells in vitro and alleviates cardiotoxicity induced by doxorubicin in vivo. Cancer Chemother Pharmacol (2003) 0.83
Antibody diversification: mutational mechanisms and oncogenesis. Immunol Res (2006) 0.82
Elevated incidence of polyp formation in APC(Min/⁺)Msh2⁻/⁻ mice is independent of nitric oxide-induced DNA mutations. PLoS One (2013) 0.81
Development of a whole cell vaccine for acute myeloid leukaemia. Cancer Immunol Immunother (2005) 0.81
Mitochondrial regulation by c-Myc and hypoxia-inducible factor-1 alpha controls sensitivity to econazole. Mol Cancer Ther (2008) 0.81
Altered spectrum of somatic hypermutation in common variable immunodeficiency disease characteristic of defective repair of mutations. Immunogenetics (2010) 0.80
AID-expressing germinal center B cells cluster normally within lymph node follicles in the absence of FDC-M1+ CD35+ follicular dendritic cells but dissipate prematurely. J Immunol (2013) 0.80
AID and caspase 8 shape the germinal center response through apoptosis. J Immunol (2013) 0.80
Forced expression of AID facilitates the isolation of class switch variants from hybridoma cells. J Immunol Methods (2006) 0.79
Increased calcium influx and ribosomal content correlate with resistance to endoplasmic reticulum stress-induced cell death in mutant leukemia cell lines. J Biol Chem (2003) 0.79
Activation-induced cytidine deaminase and aberrant germinal center selection in the development of humoral autoimmunities. Am J Pathol (2011) 0.79
Gut microbial metabolism and colon cancer: can manipulations of the microbiota be useful in the management of gastrointestinal health? Bioessays (2015) 0.78
Lack of MSH2 involvement differentiates V(D)J recombination from other non-homologous end joining events. Nucleic Acids Res (2005) 0.78
Immunoglobulin gene conversion: synthesizing antibody diversification and DNA repair. DNA Repair (Amst) (2007) 0.78
ABC50 modulates sensitivity of HL60 leukemic cells to endoplasmic reticulum (ER) stress-induced cell death. Biochem Pharmacol (2010) 0.77
The mismatch repair pathway functions normally at a non-AID target in germinal center B cells. Blood (2011) 0.77
Articular damage is associated with intraosseous inflammation in the subchondral bone marrow of joints affected by experimental inflammatory arthritis and is modified by zoledronate treatment. J Rheumatol (2007) 0.77
Secondary B cell receptor diversification is necessary for T cell mediated neuro-inflammation during experimental autoimmune encephalomyelitis. PLoS One (2013) 0.77
Effect of oral piperine on the swallow response of patients with oropharyngeal dysphagia. J Gastroenterol (2013) 0.76
Induction and assessment of class switch recombination in purified murine B cells. J Vis Exp (2010) 0.75
Missing mismatch repair: a key to T cell immortality. Leuk Lymphoma (2010) 0.75
Proteolytic effect of Cynara cardunculus rennet for use in the elaboration of 'Torta del Casar' cheese. J Dairy Res (2013) 0.75
Mutation detection of immunoglobulin V-regions by DHPLC. J Immunol Methods (2002) 0.75
Activation-induced cytidine deaminase induces DNA break repair events more frequently in the Ig switch region than other sites in the mammalian genome. Eur J Immunol (2007) 0.75