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1
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Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas.
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N Engl J Med
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2015
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5.71
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2
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Transforming fusions of FGFR and TACC genes in human glioblastoma.
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Science
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2012
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5.09
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3
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An integrative approach for in silico glioma research.
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IEEE Trans Biomed Eng
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2010
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4.55
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4
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Notch1 and notch2 have opposite effects on embryonal brain tumor growth.
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Cancer Res
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2004
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2.90
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5
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Discovery of a proneurogenic, neuroprotective chemical.
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Cell
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2010
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2.78
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6
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Hypoxia and the hypoxia-inducible-factor pathway in glioma growth and angiogenesis.
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Neuro Oncol
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2005
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2.74
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7
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Microregional extracellular matrix heterogeneity in brain modulates glioma cell invasion.
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Int J Biochem Cell Biol
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2004
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2.71
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8
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Integrated morphologic analysis for the identification and characterization of disease subtypes.
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J Am Med Inform Assoc
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2012
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2.68
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9
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Real-time magnetic resonance-guided stereotactic laser amygdalohippocampotomy for mesial temporal lobe epilepsy.
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Neurosurgery
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2014
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2.41
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10
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Temozolomide in the treatment of high-grade gliomas in children: a report from the Children's Oncology Group.
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Neuro Oncol
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2011
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2.39
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11
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'Pseudopalisading' necrosis in glioblastoma: a familiar morphologic feature that links vascular pathology, hypoxia, and angiogenesis.
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J Neuropathol Exp Neurol
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2006
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2.37
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12
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Clarifying the diffuse gliomas: an update on the morphologic features and markers that discriminate oligodendroglioma from astrocytoma.
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Am J Clin Pathol
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2005
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2.17
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13
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Pituicytoma: report of two cases and clues regarding histogenesis.
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Neurosurgery
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2004
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2.17
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14
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Reactive retinal astrocytic tumors (so-called vasoproliferative tumors): histopathologic, immunohistochemical, and genetic studies of four cases.
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Am J Ophthalmol
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2012
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2.12
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15
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The proneural molecular signature is enriched in oligodendrogliomas and predicts improved survival among diffuse gliomas.
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PLoS One
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2010
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1.86
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16
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MR imaging predictors of molecular profile and survival: multi-institutional study of the TCGA glioblastoma data set.
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Radiology
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2013
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1.77
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17
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The neuronal PAS domain protein 3 transcription factor controls FGF-mediated adult hippocampal neurogenesis in mice.
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Proc Natl Acad Sci U S A
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2005
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1.71
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18
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Cancer susceptibility variants and the risk of adult glioma in a US case-control study.
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J Neurooncol
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2011
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1.69
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19
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Integrative, multimodal analysis of glioblastoma using TCGA molecular data, pathology images, and clinical outcomes.
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IEEE Trans Biomed Eng
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2011
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1.63
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20
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Machine-based morphologic analysis of glioblastoma using whole-slide pathology images uncovers clinically relevant molecular correlates.
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PLoS One
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2013
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1.62
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21
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Vasculostatin, a proteolytic fragment of brain angiogenesis inhibitor 1, is an antiangiogenic and antitumorigenic factor.
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Oncogene
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2005
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1.61
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22
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Genetic and hypoxic regulation of angiogenesis in gliomas.
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J Neurooncol
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2004
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1.61
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23
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Depletion of peripheral macrophages and brain microglia increases brain tumor titers of oncolytic viruses.
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Cancer Res
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2007
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1.60
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24
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Aberrant methylation and down-regulation of TMS1/ASC in human glioblastoma.
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Am J Pathol
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2004
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1.58
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25
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Astroblastoma: radiologic-pathologic correlation and distinction from ependymoma.
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AJNR Am J Neuroradiol
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2002
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1.44
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26
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Genomic mapping and survival prediction in glioblastoma: molecular subclassification strengthened by hemodynamic imaging biomarkers.
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Radiology
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2012
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1.41
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27
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The contribution of protease-activated receptor 1 to neuronal damage caused by transient focal cerebral ischemia.
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Proc Natl Acad Sci U S A
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2003
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1.40
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28
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IDH1 mutations are common in malignant gliomas arising in adolescents: a report from the Children's Oncology Group.
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2010
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1.39
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29
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Vasculostatin inhibits intracranial glioma growth and negatively regulates in vivo angiogenesis through a CD36-dependent mechanism.
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Cancer Res
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2009
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1.39
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30
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Protease-activated receptor-1 in human brain: localization and functional expression in astrocytes.
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Exp Neurol
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2004
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1.36
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31
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PTEN and hypoxia regulate tissue factor expression and plasma coagulation by glioblastoma.
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Cancer Res
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2005
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1.28
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32
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Metabolomic profiling reveals potential markers and bioprocesses altered in bladder cancer progression.
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Cancer Res
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2011
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1.26
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33
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The tumor microenvironment strongly impacts master transcriptional regulators and gene expression class of glioblastoma.
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Am J Pathol
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2012
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1.25
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34
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Protocol for the examination of specimens from patients with tumors of the brain/spinal cord.
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Arch Pathol Lab Med
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2008
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1.25
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35
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Antitumor effect of 2-methoxyestradiol in a rat orthotopic brain tumor model.
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Cancer Res
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2006
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1.23
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36
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Epidermal growth factor receptor and PTEN modulate tissue factor expression in glioblastoma through JunD/activator protein-1 transcriptional activity.
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Cancer Res
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2009
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1.22
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37
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Brain angiogenesis inhibitor 1 is differentially expressed in normal brain and glioblastoma independently of p53 expression.
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Am J Pathol
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2003
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1.21
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38
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Anaplastic meningioma versus meningeal hemangiopericytoma: immunohistochemical and genetic markers.
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Hum Pathol
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2004
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1.21
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39
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Targeted cancer gene therapy using a hypoxia inducible factor dependent oncolytic adenovirus armed with interleukin-4.
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Cancer Res
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2007
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1.20
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40
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Cancer therapy with a replicating oncolytic adenovirus targeting the hypoxic microenvironment of tumors.
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Clin Cancer Res
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2004
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MORPHOLOGICAL SIGNATURES AND GENOMIC CORRELATES IN GLIOBLASTOMA.
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Proc IEEE Int Symp Biomed Imaging
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2011
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42
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A high-performance spatial database based approach for pathology imaging algorithm evaluation.
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J Pathol Inform
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2013
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43
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Caffeine-mediated inhibition of calcium release channel inositol 1,4,5-trisphosphate receptor subtype 3 blocks glioblastoma invasion and extends survival.
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Cancer Res
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2010
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1.14
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Early growth response gene-1 regulates hypoxia-induced expression of tissue factor in glioblastoma multiforme through hypoxia-inducible factor-1-independent mechanisms.
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Cancer Res
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2006
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1.13
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45
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Ancillary FISH analysis for 1p and 19q status: preliminary observations in 287 gliomas and oligodendroglioma mimics.
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Front Biosci
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2003
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1.13
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46
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Anti-invasive adjuvant therapy with imipramine blue enhances chemotherapeutic efficacy against glioma.
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Sci Transl Med
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2012
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1.12
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47
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Cancer Digital Slide Archive: an informatics resource to support integrated in silico analysis of TCGA pathology data.
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J Am Med Inform Assoc
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2013
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1.10
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Molecular genetics of gliomas.
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Cancer J
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2014
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1.09
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49
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Tumor-infiltrating lymphocytes in glioblastoma are associated with specific genomic alterations and related to transcriptional class.
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Clin Cancer Res
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2013
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1.06
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50
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Heterozygosity for Pten promotes tumorigenesis in a mouse model of medulloblastoma.
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PLoS One
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2010
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51
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Fatal West Nile virus encephalitis in a renal transplant recipient.
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2004
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52
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Primary central nervous system posttransplant lymphoproliferative disorders.
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Am J Clin Pathol
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2004
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Distinguishing chordoid meningiomas from their histologic mimics: an immunohistochemical evaluation.
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Am J Surg Pathol
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2009
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1.05
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Transgenic expression of dominant negative tuberin through a strong constitutive promoter results in a tissue-specific tuberous sclerosis phenotype in the skin and brain.
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J Biol Chem
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2004
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1.04
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55
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Human BRE1 is an E3 ubiquitin ligase for Ebp1 tumor suppressor.
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Mol Biol Cell
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2008
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1.03
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56
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Diffuse leptomeningeal neuroepithelial tumor: 9 pediatric cases with chromosome 1p/19q deletion status and IDH1 (R132H) immunohistochemistry.
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Am J Surg Pathol
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2013
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Alterations in molecular pathways of diffusely infiltrating glial neoplasms: application to tumor classification and anti-tumor therapy (Review).
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Int J Oncol
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2003
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Tuberous sclerosis complex suppression in cerebellar development and medulloblastoma: separate regulation of mammalian target of rapamycin activity and p27 Kip1 localization.
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Cancer Res
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2009
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1.01
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PDGFRA amplification is common in pediatric and adult high-grade astrocytomas and identifies a poor prognostic group in IDH1 mutant glioblastoma.
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Brain Pathol
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2013
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Genetic markers in glioblastoma: prognostic significance and future therapeutic implications.
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Adv Anat Pathol
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2003
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Magnetic resonance imaging features of pituicytomas: analysis of 10 cases.
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J Comput Assist Tomogr
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2010
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Completeness and concordancy of WHO grade assignment for brain and central nervous system tumors in the United States, 2004-2011.
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J Neurooncol
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2015
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Best cases from the AFIP: glioblastoma multiforme.
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Radiographics
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2007
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Glioblastoma with oligodendroglioma component (GBM-O): molecular genetic and clinical characteristics.
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Brain Pathol
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2013
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Differential expression between pilocytic and anaplastic astrocytomas: identification of apolipoprotein D as a marker for low-grade, non-infiltrating primary CNS neoplasms.
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J Neuropathol Exp Neurol
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2002
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Akt activation is a common event in pediatric malignant gliomas and a potential adverse prognostic marker: a report from the Children's Oncology Group.
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J Neurooncol
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2010
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Proliferation (MIB-1 expression) in oligodendrogliomas: assessment of quantitative methods and prognostic significance.
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Appl Immunohistochem Mol Morphol
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2006
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Attractin is elevated in the cerebrospinal fluid of patients with malignant astrocytoma and mediates glioma cell migration.
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Clin Cancer Res
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2006
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P14ARF inhibits human glioblastoma-induced angiogenesis by upregulating the expression of TIMP3.
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J Clin Invest
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Metastasis infiltration: an investigation of the postoperative brain-tumor interface.
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Int J Radiat Oncol Biol Phys
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Silencing of TMS1/ASC promotes resistance to anoikis in breast epithelial cells.
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Cancer Res
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2009
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Proteomic analysis of cerebrospinal fluid discriminates malignant and nonmalignant disease of the central nervous system and identifies specific protein markers.
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Proteomics
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2006
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Spinal intradural clear cell meningioma following resection of a suprasellar clear cell meningioma. Case report and recommendations for management.
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J Neurosurg
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2005
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Mismatch repair deficiency is an uncommon mechanism of alkylator resistance in pediatric malignant gliomas: a report from the Children's Oncology Group.
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Pediatr Blood Cancer
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2010
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0.88
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75
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Intravascular thrombosis in central nervous system malignancies: a potential role in astrocytoma progression to glioblastoma.
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Brain Pathol
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2007
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76
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Cancer stem cell division: when the rules of asymmetry are broken.
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Stem Cells Dev
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2014
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Diagnostic implications of IDH1-R132H and OLIG2 expression patterns in rare and challenging glioblastoma variants.
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Mod Pathol
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9p21 and 13q14 dosages in ependymomas. A clinicopathologic study of 101 cases.
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Mod Pathol
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2004
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Granular cell astrocytomas show a high frequency of allelic loss but are not a genetically defined subset.
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Brain Pathol
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2003
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Special lecture: glial reactivity after damage: implications for scar formation and neuronal recovery.
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Clin Neurosurg
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Adv Anat Pathol
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Delivery systems and molecular targets of mechanism-based therapies for GBM.
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Expert Rev Neurother
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Where are we now? And where are we going? A report from the Accelerate Brain Cancer Cure (ABC2) low-grade glioma research workshop.
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Neuro Oncol
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Differential expression of folate receptor in pituitary adenomas.
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2003
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Chordoid glioma: a case report and molecular characterization of five cases.
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Brain Pathol
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Progesterone inhibits the growth of human neuroblastoma: in vitro and in vivo evidence.
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Oncogenic regulation of tissue factor and thrombosis in cancer.
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Thromb Res
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Blockade of glioma proliferation through allosteric inhibition of JAK2.
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Sci Signal
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Galectin-3 expression is ubiquitous in tumors of the sellar region, nervous system, and mimics: an immunohistochemical and RT-PCR study.
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P14ARF suppresses tumor-induced thrombosis by regulating the tissue factor pathway.
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Lectins identify glycan biomarkers on glioblastoma-derived cancer stem cells.
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The elusive origin of chordoid glioma.
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Arch Pathol Lab Med
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Glioblastoma occurring at the site of a previous medulloblastoma following a 5-year remission period.
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An astroblastoma mimicking a cavernous malformation: case report.
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De novo germline TP53 mutation presenting with synchronous malignancies of the central nervous system.
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The use of neuroimaging to guide the histologic diagnosis of central nervous system lesions.
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Upregulation of hypoxia inducible factor is associated with attenuation of neuronal injury in neonatal piglets undergoing deep hypothermic circulatory arrest.
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Visualizing cancer and response to therapy in vivo using Cy5.5-labeled factor VIIa and anti-tissue factor antibody.
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May 2003: 57-year-old-woman with acute loss of strength in her right upper extremity and slurred speech.
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Acute monocular visual loss in an elderly woman: a neuro-ophthalmologic emergency.
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P53 tumor suppression network in cancer epigenetics.
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Bilateral optic neuropathy after erythematous rash. Bilateral anterior optic neuropathy due to RMSF.
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