Osamu Yasuda

Author PubWeight™ 33.40‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Homocysteine enhances endothelial apoptosis via upregulation of Fas-mediated pathways. Hypertension 2004 1.76
2 Genetic variants at the 9p21 locus contribute to atherosclerosis through modulation of ANRIL and CDKN2A/B. Atherosclerosis 2011 1.55
3 Tissue inhibitor of metalloproteinase-3 deficiency inhibits blood pressure elevation and myocardial microvascular remodeling induced by chronic administration of Nomega-nitro-L-arginine methyl ester in mice. Hypertens Res 2007 1.47
4 Eplerenone potentiates protective effects of amlodipine against cardiovascular injury in salt-sensitive hypertensive rats. Hypertens Res 2011 1.46
5 Klotho suppresses TNF-alpha-induced expression of adhesion molecules in the endothelium and attenuates NF-kappaB activation. Endocrine 2009 1.37
6 Apoptosis signal-regulating kinase 1 mediates cellular senescence induced by high glucose in endothelial cells. Diabetes 2006 1.16
7 Ubiquitin carboxyl-terminal hydrolase L1, a novel deubiquitinating enzyme in the vasculature, attenuates NF-kappaB activation. Arterioscler Thromb Vasc Biol 2007 1.07
8 Apoptosis signal-regulating kinase 1 is a novel target molecule for cognitive impairment induced by chronic cerebral hypoperfusion. Arterioscler Thromb Vasc Biol 2013 1.03
9 Klotho protein diminishes endothelial apoptosis and senescence via a mitogen-activated kinase pathway. Geriatr Gerontol Int 2011 1.03
10 CVD-associated non-coding RNA, ANRIL, modulates expression of atherogenic pathways in VSMC. Biochem Biophys Res Commun 2012 1.01
11 Involvement of microsomal triglyceride transfer protein in nonalcoholic steatohepatitis in novel spontaneous mouse model. J Hepatol 2010 0.97
12 Novel mechanism of angiotensin II-induced cardiac injury in hypertensive rats: the critical role of ASK1 and VEGF. Hypertens Res 2011 0.92
13 Telmisartan protects against diabetic vascular complications in a mouse model of obesity and type 2 diabetes, partially through peroxisome proliferator activated receptor-γ-dependent activity. Biochem Biophys Res Commun 2011 0.89
14 Association of serum anti-periodontal pathogen antibody with ischemic stroke. Cerebrovasc Dis 2012 0.88
15 Ezetimibe ameliorates cardiovascular complications and hepatic steatosis in obese and type 2 diabetic db/db mice. J Pharmacol Exp Ther 2010 0.87
16 A polymorphism regulates CYP4A11 transcriptional activity and is associated with hypertension in a Japanese population. Hypertension 2008 0.87
17 Fas promoter region gene polymorphism is associated with an increased risk for myocardial infarction. Hypertens Res 2009 0.86
18 Tissue inhibitor of metalloproteinase-3 plays important roles in the kidney following unilateral ureteral obstruction. Hypertens Res 2006 0.86
19 Nifedipine inhibits vascular smooth muscle cell dedifferentiation via downregulation of Akt signaling. Hypertension 2010 0.86
20 Nifedipine indirectly upregulates superoxide dismutase expression in endothelial cells via vascular smooth muscle cell-dependent pathways. Circulation 2002 0.85
21 Aspirin prevents adhesion of T lymphoblasts to vascular smooth muscle cells. FEBS Lett 2007 0.85
22 Novel mechanism of salt-induced glomerular injury: critical role of eNOS and angiotensin II. J Hypertens 2011 0.85
23 Potential role of CYLD (Cylindromatosis) as a deubiquitinating enzyme in vascular cells. Am J Pathol 2008 0.85
24 Novel mechanism for disrupted circadian blood pressure rhythm in a rat model of metabolic syndrome--the critical role of angiotensin II. J Am Heart Assoc 2013 0.83
25 Fas signaling induces Akt activation and upregulation of endothelial nitric oxide synthase expression. Hypertension 2004 0.83
26 Nifedipine prevents vascular endothelial dysfunction in a mouse model of obesity and type 2 diabetes, by improving eNOS dysfunction and dephosphorylation. Biochem Biophys Res Commun 2010 0.82
27 Level of serum antibody against a periodontal pathogen is associated with atherosclerosis and hypertension. Hypertens Res 2013 0.80
28 Amlodipine enhances amelioration of vascular insulin resistance, oxidative stress, and metabolic disorders by candesartan in metabolic syndrome rats. Am J Hypertens 2012 0.80
29 Passive exercise using whole-body periodic acceleration enhances blood supply to ischemic hindlimb. Arterioscler Thromb Vasc Biol 2011 0.79
30 Decreased thalamic metabolism without thalamic magnetic resonance imaging abnormalities following shearing injury to the substantia nigra. J Clin Neurosci 2002 0.79
31 Eicosapentaenoic acid protects endothelial cells against anoikis through restoration of cFLIP. Hypertension 2003 0.78
32 Akt activation prevents Apop-1-induced death of cells. Biochem Biophys Res Commun 2008 0.78
33 Calcium channel blockers, more than diuretics, enhance vascular protective effects of angiotensin receptor blockers in salt-loaded hypertensive rats. PLoS One 2012 0.77
34 Timp-3 deficiency impairs cognitive function in mice. Lab Invest 2009 0.76
35 A novel Doppler echocardiographic score reflecting cardiac functional status can predict adverse outcome in acute myocardial infarction. J Echocardiogr 2012 0.75
36 Fas ligand mRNA levels of circulating leukocytes reflect endothelial dysfunction in hyperlipidemic but not in non-hyperlipidemic patients. Hypertens Res 2006 0.75
37 [A lesion diagnosed by MRI in a case of transient global amnesia]. No To Shinkei 2002 0.75
38 Kumamoto Earthquake and health issues of the elderly. Nihon Ronen Igakkai Zasshi 2017 0.75
39 [Crucial role of apoptogenic protein in cellular apoptosis and senescense]. Nihon Ronen Igakkai Zasshi 2011 0.75
40 Erratum: ASK1 is involved in cognitive impairment caused by long-term high-fat diet feeding in mice. Sci Rep 2015 0.75
41 Nifedipine upregulates manganese superoxide dismutase expression in vascular smooth muscle cells via endothelial cell-dependent pathways. Hypertens Res 2003 0.75
42 Gastric mucosa-associated lymphoid tissue lymphoma with adult T cell leukemia/lymphoma cell infiltration. case report. Am J Gastroenterol 2003 0.75
43 Case report of a long-surviving Werner syndrome patient with severe aortic valve stenosis. Geriatr Gerontol Int 2012 0.75