Published in Fungal Genet Biol on March 01, 2012
Translating biosynthetic gene clusters into fungal armor and weaponry. Nat Chem Biol (2015) 0.92
Perturbations in small molecule synthesis uncovers an iron-responsive secondary metabolite network in Aspergillus fumigatus. Front Microbiol (2014) 0.91
The Aspergillus fumigatus protein GliK protects against oxidative stress and is essential for gliotoxin biosynthesis. Eukaryot Cell (2012) 0.90
RsmA regulates Aspergillus fumigatus gliotoxin cluster metabolites including cyclo(L-Phe-L-Ser), a potential new diagnostic marker for invasive aspergillosis. PLoS One (2013) 0.88
Redox metabolites signal polymicrobial biofilm development via the NapA oxidative stress cascade in Aspergillus. Curr Biol (2014) 0.86
Redundant synthesis of a conidial polyketide by two distinct secondary metabolite clusters in Aspergillus fumigatus. Environ Microbiol (2015) 0.84
Exploration of Sulfur Assimilation of Aspergillus fumigatus Reveals Biosynthesis of Sulfur-Containing Amino Acids as a Virulence Determinant. Infect Immun (2016) 0.84
RNA-seq reveals the pan-transcriptomic impact of attenuating the gliotoxin self-protection mechanism in Aspergillus fumigatus. BMC Genomics (2014) 0.83
A proteomic approach to investigating gene cluster expression and secondary metabolite functionality in Aspergillus fumigatus. PLoS One (2014) 0.82
Systematic Global Analysis of Genes Encoding Protein Phosphatases in Aspergillus fumigatus. G3 (Bethesda) (2015) 0.79
Extensive proteomic remodeling is induced by eukaryotic translation elongation factor 1Bγ deletion in Aspergillus fumigatus. Protein Sci (2013) 0.77
Disparate proteome responses of pathogenic and nonpathogenic aspergilli to human serum measured by activity-based protein profiling (ABPP). Mol Cell Proteomics (2013) 0.76
Structural, mechanistic and functional insight into gliotoxin bis-thiomethylation in Aspergillus fumigatus. Open Biol (2017) 0.76
Ergothioneine Biosynthesis and Functionality in the Opportunistic Fungal Pathogen, Aspergillus fumigatus. Sci Rep (2016) 0.75
Towards understanding the gliotoxin detoxification mechanism: in vivo thiomethylation protects yeast from gliotoxin cytotoxicity. Microb Cell (2016) 0.75
A model for the roll-out of comprehensive adult male circumcision services in African low-income settings of high HIV incidence: the ANRS 12126 Bophelo Pele Project. PLoS Med (2010) 2.43
Correlation between virulence of Candida albicans mutants in mice and Galleria mellonella larvae. FEMS Immunol Med Microbiol (2002) 2.00
Synthesis, antimicrobial activity and chemotherapeutic potential of inorganic derivatives of 2-(4'-thiazolyl)benzimidazole[thiabendazole]: X-ray crystal structures of [Cu(TBZH)2Cl]Cl.H2O.EtOH and TBZH2NO3 (TBZH=thiabendazole). J Inorg Biochem (2004) 1.82
Advances in the biology, diagnosis and host-pathogen interactions of parvovirus B19. J Med Microbiol (2004) 1.51
Superoxide production in Galleria mellonella hemocytes: identification of proteins homologous to the NADPH oxidase complex of human neutrophils. Infect Immun (2005) 1.46
Self-protection against gliotoxin--a component of the gliotoxin biosynthetic cluster, GliT, completely protects Aspergillus fumigatus against exogenous gliotoxin. PLoS Pathog (2010) 1.44
Cathepsin L1, the major protease involved in liver fluke (Fasciola hepatica) virulence: propetide cleavage sites and autoactivation of the zymogen secreted from gastrodermal cells. J Biol Chem (2004) 1.36
Fluctuations in haemocyte density and microbial load may be used as indicators of fungal pathogenicity in larvae of Galleria mellonella. Microbes Infect (2003) 1.34
Fasciola hepatica cathepsin L-like proteases: biology, function, and potential in the development of first generation liver fluke vaccines. Int J Parasitol (2003) 1.32
CDK-dependent Hsp70 Phosphorylation controls G1 cyclin abundance and cell-cycle progression. Cell (2012) 1.29
Type III IFNs are produced by and stimulate human plasmacytoid dendritic cells. J Immunol (2012) 1.23
A nonribosomal peptide synthetase (Pes1) confers protection against oxidative stress in Aspergillus fumigatus. FEBS J (2006) 1.19
Multiplex immunoassay for serological diagnosis of Mycobacterium bovis infection in cattle. Clin Vaccine Immunol (2008) 1.19
NS1 protein of parvovirus B19 interacts directly with DNA sequences of the p6 promoter and with the cellular transcription factors Sp1/Sp3. Virology (2002) 1.17
Candida urinary tract infection: pathogenesis. Clin Infect Dis (2011) 1.16
Pre-exposure to yeast protects larvae of Galleria mellonella from a subsequent lethal infection by Candida albicans and is mediated by the increased expression of antimicrobial peptides. Microbes Infect (2006) 1.16
Effect of pre-incubation temperature on susceptibility of Galleria mellonella larvae to infection by Candida albicans. Mycopathologia (2007) 1.13
Insights into the mechanism of prion propagation. Curr Opin Struct Biol (2008) 1.13
Susceptibility of larvae of Galleria mellonella to infection by Aspergillus fumigatus is dependent upon stage of conidial germination. Mycopathologia (2006) 1.12
Hsp40 interacts directly with the native state of the yeast prion protein Ure2 and inhibits formation of amyloid-like fibrils. J Biol Chem (2007) 1.11
Leucine aminopeptidase of the human blood flukes, Schistosoma mansoni and Schistosoma japonicum. Int J Parasitol (2004) 1.09
Physical stress primes the immune response of Galleria mellonella larvae to infection by Candida albicans. Microbes Infect (2008) 1.09
Importance of the Hsp70 ATPase domain in yeast prion propagation. Genetics (2006) 1.06
The role of glutathione S-transferase GliG in gliotoxin biosynthesis in Aspergillus fumigatus. Chem Biol (2011) 1.05
The roles of whole-genome and small-scale duplications in the functional specialization of Saccharomyces cerevisiae genes. PLoS Genet (2013) 1.05
Potential role of Demodex mites and bacteria in the induction of rosacea. J Med Microbiol (2012) 1.04
Correlation between ocular Demodex infestation and serum immunoreactivity to Bacillus proteins in patients with Facial rosacea. Ophthalmology (2010) 1.04
Galleria mellonella as a model for fungal pathogenicity testing. Methods Mol Biol (2012) 1.03
Identification, cloning, and functional expression of three glutathione transferase genes from Aspergillus fumigatus. Fungal Genet Biol (2005) 1.01
Effect of nutrient deprivation on the susceptibility of Galleria mellonella larvae to infection. Virulence (2012) 1.00
Genomic and proteomic dissection of the ubiquitous plant pathogen, Armillaria mellea: toward a new infection model system. J Proteome Res (2013) 1.00
The expression of selected non-ribosomal peptide synthetases in Aspergillus fumigatus is controlled by the availability of free iron. FEMS Microbiol Lett (2005) 1.00
The shortened replicative life span of prohibitin mutants of yeast appears to be due to defective mitochondrial segregation in old mother cells. Aging Cell (2002) 0.98
Nonribosomal peptide synthesis in Aspergillus fumigatus and other fungi. Microbiology (2007) 0.96
Use of Galleria mellonella larvae to evaluate the in vivo anti-fungal activity of [Ag2(mal)(phen)3]. Biometals (2008) 0.96
Dose-dependent cellular and humoral responses in Galleria mellonella larvae following beta-glucan inoculation. Microbes Infect (2009) 0.95
Disruption of mitochondrial function in Candida albicans leads to reduced cellular ergosterol levels and elevated growth in the presence of amphotericin B. Arch Microbiol (2003) 0.95
Nonribosomal peptide synthetase genes pesL and pes1 are essential for Fumigaclavine C production in Aspergillus fumigatus. Appl Environ Microbiol (2012) 0.94
Pre-exposure of Galleria mellonella larvae to different doses of Aspergillus fumigatus conidia causes differential activation of cellular and humoral immune responses. Virulence (2011) 0.93
The Aspergillus fumigatus toxin fumagillin suppresses the immune response of Galleria mellonella larvae by inhibiting the action of haemocytes. Microbiology (2011) 0.92
B cell memory is directed toward conformational epitopes of parvovirus B19 capsid proteins and the unique region of VP1. J Infect Dis (2004) 0.91
An analysis of the structural and functional similarities of insect hemocytes and mammalian phagocytes. Virulence (2013) 0.91
Caspofungin primes the immune response of the larvae of Galleria mellonella and induces a non-specific antimicrobial response. J Med Microbiol (2010) 0.91
Reconstructing the fungal tree of life using phylogenomics and a preliminary investigation of the distribution of yeast prion-like proteins in the fungal kingdom. J Mol Evol (2011) 0.90
The Aspergillus fumigatus protein GliK protects against oxidative stress and is essential for gliotoxin biosynthesis. Eukaryot Cell (2012) 0.90
Steered molecular dynamics simulations on the binding of the appendant structure and helix-β2 in domain-swapped human cystatin C dimer. J Biomol Struct Dyn (2012) 0.89
Under the lash: Demodex mites in human diseases. Biochem (Lond) (2009) 0.89
The effect of Aspergillus fumigatus infection on vitamin D receptor expression in cystic fibrosis. Am J Respir Crit Care Med (2012) 0.89
Analysis of major intracellular proteins of Aspergillus fumigatus by MALDI mass spectrometry: identification and characterisation of an elongation factor 1B protein with glutathione transferase activity. Biochem Biophys Res Commun (2006) 0.89
Mechanism of action of coumarin and silver(I)-coumarin complexes against the pathogenic yeast Candida albicans. Toxicol In Vitro (2007) 0.88
Examination of the bovine leukocyte environment using immunogenetic biomarkers to assess immunocompetence following exposure to weaning stress. BMC Vet Res (2011) 0.87
Influence of specific HSP70 domains on fibril formation of the yeast prion protein Ure2. Philos Trans R Soc Lond B Biol Sci (2013) 0.87
Induction of apoptosis in yeast and mammalian cells by exposure to 1,10-phenanthroline metal complexes. Toxicol In Vitro (2004) 0.87
Amphotericin B enhances the synthesis and release of the immunosuppressive agent gliotoxin from the pulmonary pathogen Aspergillus fumigatus. J Med Microbiol (2004) 0.87
Targeted disruption of nonribosomal peptide synthetase pes3 augments the virulence of Aspergillus fumigatus. Infect Immun (2011) 0.87
Mode of anti-fungal activity of 1,10-phenanthroline and its Cu(II), Mn(II) and Ag(I) complexes. Biometals (2003) 0.86
Transcriptomic analysis of the stress response to weaning at housing in bovine leukocytes using RNA-seq technology. BMC Genomics (2012) 0.86
Trichophyton violaceum is the dominant cause of tinea capitis in children in Tripoli, Libya: results of a two year survey. Mycopathologia (2002) 0.85
Erythromycin, an inhibitor of mitoribosomal protein biosynthesis, alters the amphotericin B susceptibility of Candida albicans. J Pharm Pharmacol (2003) 0.85
Inhibition of neutrophil function following exposure to the Aspergillus fumigatus toxin fumagillin. J Med Microbiol (2010) 0.85
Exposure to caspofungin activates Cap and Hog pathways in Candida albicans. Med Mycol (2009) 0.85
Immunoproteomic analysis of proteins expressed by two related pathogens, Burkholderia multivorans and Burkholderia cenocepacia, during human infection. PLoS One (2013) 0.84
In vitro anti-tumour and cyto-selective effects of coumarin-3-carboxylic acid and three of its hydroxylated derivatives, along with their silver-based complexes, using human epithelial carcinoma cell lines. Cancer Lett (2006) 0.84
Effect of N-chlorotaurine on Aspergillus, with particular reference to destruction of secreted gliotoxin. J Med Microbiol (2006) 0.84
Alcohol oxidase (AOX1) from Pichia pastoris is a novel inhibitor of prion propagation and a potential ATPase. Mol Microbiol (2008) 0.84
The yeast prion protein Ure2: structure, function and folding. Biochim Biophys Acta (2005) 0.84
Prolonged pre-incubation increases the susceptibility of Galleria mellonella larvae to bacterial and fungal infection. Virulence (2015) 0.84
Biomarkers for invasive aspergillosis: the challenges continue. Biomark Med (2014) 0.83
Translocation of proteins homologous to human neutrophil p47phox and p67phox to the cell membrane in activated hemocytes of Galleria mellonella. Dev Comp Immunol (2006) 0.83
RNA-seq reveals the pan-transcriptomic impact of attenuating the gliotoxin self-protection mechanism in Aspergillus fumigatus. BMC Genomics (2014) 0.83
A 4'-phosphopantetheinyl transferase mediates non-ribosomal peptide synthetase activation in Aspergillus fumigatus. Chembiochem (2005) 0.82
A new phenanthroline-oxazine ligand: synthesis, coordination chemistry and atypical DNA binding interaction. Chem Commun (Camb) (2013) 0.82
Synthesis, X-ray crystal structure, anti-fungal and anti-cancer activity of [Ag2(NH3)2(salH)2] (salH2=salicylic acid). J Inorg Biochem (2004) 0.82
Role of cell cycle events and apoptosis in mediating the anti-cancer activity of a silver(I) complex of 4-hydroxy-3-nitro-coumarin-bis(phenanthroline) in human malignant cancer cells. Eur J Pharmacol (2008) 0.82
Correlation between serum reactivity to Demodex-associated Bacillus oleronius proteins, and altered sebum levels and Demodex populations in erythematotelangiectatic rosacea patients. J Med Microbiol (2013) 0.82
Ex vivo cytokine responses against parvovirus B19 antigens in previously infected pregnant women. J Med Virol (2003) 0.81
Optimization of xylanase production by Thermomyces lanuginosus in solid state fermentation. Biosci Biotechnol Biochem (2009) 0.81
Effect of pre-weaning concentrate supplementation on peripheral distribution of leukocytes, functional activity of neutrophils, acute phase protein and behavioural responses of abruptly weaned and housed beef calves. BMC Vet Res (2012) 0.81
Metal complexes of 1,10-phenanthroline-5,6-dione alter the susceptibility of the yeast Candida albicans to amphotericin B and miconazole. Biometals (2004) 0.80
Disruption of haemocyte function by exposure to cytochalasin b or nocodazole increases the susceptibility of Galleria mellonella larvae to infection. Microbes Infect (2011) 0.80
Using steered molecular dynamics to predict and assess Hsp70 substrate-binding domain mutants that alter prion propagation. PLoS Comput Biol (2013) 0.80
Mutational analysis of Sse1 (Hsp110) suggests an integral role for this chaperone in yeast prion propagation in vivo. G3 (Bethesda) (2013) 0.80
Assessment of inactivating stop codon mutations in forty Saccharomyces cerevisiae strains: implications for [PSI] prion- mediated phenotypes. PLoS One (2011) 0.80
Apoptotic cell death: a possible key event in mediating the in vitro anti-proliferative effect of a novel copper(II) complex, [Cu(4-Mecdoa)(phen)(2)] (phen=phenanthroline, 4-Mecdoa=4-methylcoumarin-6,7-dioxactetate), in human malignant cancer cells. Eur J Pharmacol (2007) 0.79