Published in Arch Intern Med on March 12, 2012
The opportunity cost of futile treatment in the ICU*. Crit Care Med (2014) 3.21
Critical care bed growth in the United States. A comparison of regional and national trends. Am J Respir Crit Care Med (2015) 1.93
ICU occupancy and mechanical ventilator use in the United States. Crit Care Med (2013) 1.87
Aggressiveness of intensive care use among patients with lung cancer in the Surveillance, Epidemiology, and End Results-Medicare registry. Chest (2014) 1.78
Objective factors associated with physicians' and nurses' perceptions of intensive care unit capacity strain. Ann Am Thorac Soc (2014) 1.68
Effect of ICU strain on timing of limitations in life-sustaining therapy and on death. Intensive Care Med (2016) 0.87
County-Level Effects of Prehospital Regionalization of Critically Ill Patients: A Simulation Study. Crit Care Med (2015) 0.87
Outcomes of direct and indirect medical intensive care unit admissions from the emergency department of an acute care hospital: a retrospective cohort study. BMJ Open (2014) 0.86
Deferred admission to the intensive care unit: rationing critical care or expediting care transitions? Arch Intern Med (2012) 0.85
Does space make waste? The influence of ICU bed capacity on admission decisions. Crit Care (2013) 0.84
Acute kidney injury among critically ill patients with pandemic H1N1 influenza A in Canada: cohort study. BMC Nephrol (2013) 0.80
International comparisons of intensive care: informing outcomes and improving standards. Curr Opin Crit Care (2012) 0.80
Association between age and use of intensive care among surgical Medicare beneficiaries. J Crit Care (2013) 0.80
Nighttime physician staffing improves patient outcomes: yes. Intensive Care Med (2016) 0.80
Relationship between ICU bed availability, ICU readmission, and cardiac arrest in the general wards. Crit Care Med (2014) 0.79
Assessing the association between occupancy and outcome in critically Ill hospitalized patients with sepsis. BMC Emerg Med (2015) 0.78
Influence of ICU-bed availability on ICU admission decisions. Ann Intensive Care (2015) 0.77
Quality and performance measures of strain on intensive care capacity: a protocol for a systematic review. Syst Rev (2015) 0.77
Critical care capacity in Canada: results of a national cross-sectional study. Crit Care (2015) 0.76
The Effect of Intensive Care Unit Admission Patterns on Mortality-based Critical Care Performance Measures. Ann Am Thorac Soc (2016) 0.75
Patient outcomes vs. service workload: an analysis of outcomes in the burn service of England and Wales. BMC Health Serv Res (2015) 0.75
Advance care planning of the acutely unwell patient. Arch Intern Med (2012) 0.75
Rapid response teams and end-of-life care. Can Respir J (2014) 0.75
Health care prioritization: a clinician's duty. Can J Kidney Health Dis (2014) 0.75
Long-term outcomes and healthcare utilization following critical illness - a population-based study. Crit Care (2016) 0.75
Cost effectiveness of intensive care in a low resource setting: A prospective cohort of medical critically ill patients. World J Crit Care Med (2016) 0.75
Risk of Death Influences Regional Variation in Intensive Care Unit Admission Rates among the Elderly in the United States. PLoS One (2016) 0.75
Intensive Care Medicine in 2050: toward an intensive care unit without waste. Intensive Care Med (2016) 0.75
Mortality Associated with Night and Weekend Admissions to ICU with On-Site Intensivist Coverage: Results of a Nine-Year Cohort Study (2006-2014). PLoS One (2016) 0.75
Triage of Patients Consulted for ICU Admission During Times of ICU-Bed Shortage. J Clin Med Res (2014) 0.75
Intensive care unit strain should not rush physicians into making inappropriate decisions, but merely reduce the time to the right decisions being made. Ann Transl Med (2016) 0.75
Trends in assisted ventilation and outcome for obstructive pulmonary disease exacerbations. A nationwide study. PLoS One (2017) 0.75
Response. Chest (2015) 0.75
Sustaining critical care: using evidence-based simulation to evaluate ICU management policies. Health Care Manag Sci (2016) 0.75
A multi-center prospective cohort study of patient transfers from the intensive care unit to the hospital ward. Intensive Care Med (2017) 0.75
A randomized, controlled trial of the use of pulmonary-artery catheters in high-risk surgical patients. N Engl J Med (2003) 10.13
Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood. Nat Med (2007) 8.58
Comparison of risk prediction using the CKD-EPI equation and the MDRD study equation for estimated glomerular filtration rate. JAMA (2012) 6.26
Effectiveness of quality improvement strategies on the management of diabetes: a systematic review and meta-analysis. Lancet (2012) 5.65
Effect of frequent nocturnal hemodialysis vs conventional hemodialysis on left ventricular mass and quality of life: a randomized controlled trial. JAMA (2007) 5.31
A systematic evaluation of the quality of meta-analyses in the critical care literature. Crit Care (2005) 4.51
Risk of coronary events in people with chronic kidney disease compared with those with diabetes: a population-level cohort study. Lancet (2012) 4.25
CATCH: a clinical decision rule for the use of computed tomography in children with minor head injury. CMAJ (2010) 4.03
Prognosis for long-term survival and renal recovery in critically ill patients with severe acute renal failure: a population-based study. Crit Care (2005) 3.96
Discovery and validation of cell cycle arrest biomarkers in human acute kidney injury. Crit Care (2013) 3.90
Cardio-renal syndromes: report from the consensus conference of the acute dialysis quality initiative. Eur Heart J (2009) 3.52
Using proteinuria and estimated glomerular filtration rate to classify risk in patients with chronic kidney disease: a cohort study. Ann Intern Med (2011) 3.49
Chronic kidney disease and cardiovascular risk: epidemiology, mechanisms, and prevention. Lancet (2013) 3.44
Oral phosphate binders in patients with kidney failure. N Engl J Med (2010) 3.42
Major complications, mortality, and resource utilization after open abdominal surgery: 0.9% saline compared to Plasma-Lyte. Ann Surg (2012) 3.36
The association between renal replacement therapy modality and long-term outcomes among critically ill adults with acute kidney injury: a retrospective cohort study*. Crit Care Med (2014) 3.29
Intensive and Standard Blood Pressure Targets in Patients With Type 2 Diabetes Mellitus: Systematic Review and Meta-analysis. Arch Intern Med (2012) 3.26
Early recognition and prevention of chronic kidney disease. Lancet (2010) 3.19
Syntheses, crystal structures, and magnetic characterization of five new dimeric manganese(III) tetradentate Schiff base complexes exhibiting single-molecule-magnet behavior. Inorg Chem (2006) 3.18
Association between glycemic control and adverse outcomes in people with diabetes mellitus and chronic kidney disease: a population-based cohort study. Arch Intern Med (2011) 3.13
Prognostic value of troponin T and I among asymptomatic patients with end-stage renal disease: a meta-analysis. Circulation (2005) 3.10
Cost analysis of ongoing care of patients with end-stage renal disease: the impact of dialysis modality and dialysis access. Am J Kidney Dis (2002) 3.06
Change in the estimated glomerular filtration rate over time and risk of all-cause mortality. Kidney Int (2013) 3.05
A systematic review of the effect of nocturnal hemodialysis on blood pressure, left ventricular hypertrophy, anemia, mineral metabolism, and health-related quality of life. Kidney Int (2005) 3.03
Epidemiology of acute kidney injury in critically ill patients: the multinational AKI-EPI study. Intensive Care Med (2015) 2.97
Glomerular filtration rate, proteinuria, and the incidence and consequences of acute kidney injury: a cohort study. Lancet (2010) 2.95
Oral estrogen therapy in postmenopausal women is associated with loss of kidney function. Kidney Int (2008) 2.88
The draft genome of sweet orange (Citrus sinensis). Nat Genet (2012) 2.81
The Very Elderly Admitted to ICU: A Quality Finish? Crit Care Med (2015) 2.77
Validation of a case definition to define hypertension using administrative data. Hypertension (2009) 2.74
A comparison of early versus late initiation of renal replacement therapy in critically ill patients with acute kidney injury: a systematic review and meta-analysis. Crit Care (2011) 2.60
Percutaneous dilatational tracheostomy versus surgical tracheostomy in critically ill patients: a systematic review and meta-analysis. Crit Care (2006) 2.55
Guidelines for the management of chronic kidney disease. CMAJ (2008) 2.54
Synthesis, functionalization, and biomedical applications of multifunctional magnetic nanoparticles. Adv Mater (2010) 2.52
Sodium bicarbonate to prevent increases in serum creatinine after cardiac surgery: a pilot double-blind, randomized controlled trial. Crit Care Med (2009) 2.45
Efficacy of statins for primary prevention in people at low cardiovascular risk: a meta-analysis. CMAJ (2011) 2.40
Severe bloodstream infections: a population-based assessment. Crit Care Med (2004) 2.39
Mycophenolate mofetil for induction therapy of lupus nephritis: a systematic review and meta-analysis. Clin J Am Soc Nephrol (2007) 2.38
Systematic review of the impact of N-acetylcysteine on contrast nephropathy. Kidney Int (2004) 2.37
Association between LDL-C and risk of myocardial infarction in CKD. J Am Soc Nephrol (2013) 2.34
Estimate of the benefits of a population-based reduction in dietary sodium additives on hypertension and its related health care costs in Canada. Can J Cardiol (2007) 2.32
Weekend hospital admission, acute kidney injury, and mortality. J Am Soc Nephrol (2010) 2.30
Associations of estimated glomerular filtration rate and albuminuria with mortality and renal failure by sex: a meta-analysis. BMJ (2013) 2.24
Renal replacement therapy in patients with acute renal failure: a systematic review. JAMA (2008) 2.22
Associations between hemodialysis access type and clinical outcomes: a systematic review. J Am Soc Nephrol (2013) 2.22
Systematic review of the clinical efficacy and safety of sevelamer in dialysis patients. Nephrol Dial Transplant (2007) 2.18
CKD and risk of hospitalization and death with pneumonia. Am J Kidney Dis (2009) 2.17
Proteinuria and life expectancy. Am J Kidney Dis (2012) 2.16
Crystal structure of nucleotide-free dynamin. Nature (2011) 2.13
Impact of anemia on hospitalization and mortality in older adults. Blood (2006) 2.07
Higher estimated glomerular filtration rates may be associated with increased risk of adverse outcomes, especially with concomitant proteinuria. Kidney Int (2011) 2.07
Meta-analysis: antibiotics for prophylaxis against hemodialysis catheter-related infections. Ann Intern Med (2008) 2.06
The NLRP3 inflammasome promotes renal inflammation and contributes to CKD. J Am Soc Nephrol (2010) 2.04
Prognostic implications of the urinary albumin to creatinine ratio in veterans of different ages with diabetes. Arch Intern Med (2010) 2.03
Cardiovascular outcomes in framingham participants with diabetes: the importance of blood pressure. Hypertension (2011) 2.02
Pathophysiology of septic acute kidney injury: what do we really know? Crit Care Med (2008) 2.02
Short-term change in kidney function and risk of end-stage renal disease. Nephrol Dial Transplant (2012) 2.01
A review on the importance of metals and metalloids in atmospheric dust and aerosol from mining operations. Sci Total Environ (2012) 1.95
Non-neurologic organ dysfunction in severe traumatic brain injury. Crit Care Med (2005) 1.95
Transient azotaemia is associated with a high risk of death in hospitalized patients. Nephrol Dial Transplant (2010) 1.92
Access to health care among status Aboriginal people with chronic kidney disease. CMAJ (2008) 1.91
Limited ability of SOFA and MOD scores to discriminate outcome: a prospective evaluation in 1,436 patients. Can J Anaesth (2005) 1.90
Chronic kidney disease and life expectancy. Nephrol Dial Transplant (2012) 1.90
Quality of care and mortality are worse in chronic kidney disease patients living in remote areas. Kidney Int (2010) 1.89
Prevalence of adenomas and colorectal cancer in average risk individuals: a systematic review and meta-analysis. Clin Gastroenterol Hepatol (2009) 1.88
The 2012 Canadian hypertension education program recommendations for the management of hypertension: blood pressure measurement, diagnosis, assessment of risk, and therapy. Can J Cardiol (2012) 1.86
Oliguria as predictive biomarker of acute kidney injury in critically ill patients. Crit Care (2011) 1.86
A randomized trial comparing buttonhole with rope ladder needling in conventional hemodialysis patients. Clin J Am Soc Nephrol (2012) 1.85
One-year mortality of bloodstream infection-associated sepsis and septic shock among patients presenting to a regional critical care system. Intensive Care Med (2005) 1.85
Associations between acute kidney injury and cardiovascular and renal outcomes after coronary angiography. Circulation (2011) 1.85
Optimizing the use of prescription drugs in Canada through the Common Drug Review. CMAJ (2008) 1.80
The quality of reports of critical care meta-analyses in the Cochrane Database of Systematic Reviews: an independent appraisal. Crit Care Med (2007) 1.77
Acute renal failure in the intensive care unit: a systematic review of the impact of dialytic modality on mortality and renal recovery. Am J Kidney Dis (2002) 1.75
NSAID use and progression of chronic kidney disease. Am J Med (2007) 1.75
Evaluation of continuous positive airway pressure therapy on renin-angiotensin system activity in obstructive sleep apnea. Am J Respir Crit Care Med (2014) 1.74
Phase II, randomized, controlled trial of high-dose N-acetylcysteine in high-risk cardiac surgery patients. Crit Care Med (2007) 1.74
Declining kidney function increases the prevalence of sleep apnea and nocturnal hypoxia. Chest (2012) 1.73
High-volume versus standard-volume haemofiltration for septic shock patients with acute kidney injury (IVOIRE study): a multicentre randomized controlled trial. Intensive Care Med (2013) 1.73
Myosin light chain kinase is central to smooth muscle contraction and required for gastrointestinal motility in mice. Gastroenterology (2008) 1.72
Urinary biochemistry in experimental septic acute renal failure. Nephrol Dial Transplant (2006) 1.69
Comprehensive long-span paired-end-tag mapping reveals characteristic patterns of structural variations in epithelial cancer genomes. Genome Res (2011) 1.67
Attitudes toward strategies to increase organ donation: views of the general public and health professionals. Clin J Am Soc Nephrol (2012) 1.66
Azide-bridged one-dimensional Mn(III) polymers: effects of side group of Schiff base ligands on structure and magnetism. Inorg Chem (2007) 1.65
Kidney stones and cardiovascular events: a cohort study. Clin J Am Soc Nephrol (2013) 1.65
Fluid balance as a biomarker: impact of fluid overload on outcome in critically ill patients with acute kidney injury. Crit Care (2008) 1.64
The 2009 Canadian Hypertension Education Program recommendations for the management of hypertension: Part 1--blood pressure measurement, diagnosis and assessment of risk. Can J Cardiol (2009) 1.64
Sequential Organ Failure Assessment in H1N1 pandemic planning. Crit Care Med (2011) 1.63
One-year mortality in critically ill patients by severity of kidney dysfunction: a population-based assessment. Am J Kidney Dis (2006) 1.62
Validation of the Ottawa Knee Rule in children: a multicenter study. Ann Emerg Med (2003) 1.61
The role of the medical emergency team in end-of-life care: a multicenter, prospective, observational study. Crit Care Med (2012) 1.61
Kidney stones and kidney function loss: a cohort study. BMJ (2012) 1.58
Analyses of genetic structure of Tibeto-Burman populations reveals sex-biased admixture in southern Tibeto-Burmans. Am J Hum Genet (2004) 1.57
A novel molecular ladder structure of Cu(II)-Ba(II) coordination polymer exhibiting ferromagnetic coupling. Chem Commun (Camb) (2003) 1.57