Published in Phytomedicine on March 13, 2012
Yokukan-san: a review of the evidence for use of this Kampo herbal formula in dementia and psychiatric conditions. Neuropsychiatr Dis Treat (2014) 0.99
New possibility of traditional Chinese and Japanese medicine as treatment for behavioral and psychiatric symptoms in dementia. Clin Interv Aging (2012) 0.86
Efficacy and safety of yokukansan in treatment-resistant schizophrenia: a randomized, double-blind, placebo-controlled trial (a Positive and Negative Syndrome Scale, five-factor analysis). Psychopharmacology (Berl) (2014) 0.84
Yokukansan, a kampo medicine, protects PC12 cells from glutamate-induced death by augmenting gene expression of cystine/glutamate antiporter system Xc-. PLoS One (2014) 0.80
Herbal Medicine for the Treatment of Vascular Dementia: An Overview of Scientific Evidence. Evid Based Complement Alternat Med (2016) 0.75
Yokukansan improves behavioral and psychological symptoms of dementia by suppressing dopaminergic function. Neuropsychiatr Dis Treat (2016) 0.75
Efficacy and safety of yokukansan in treatment-resistant schizophrenia: a randomized, multicenter, double-blind, placebo-controlled trial. Evid Based Complement Alternat Med (2015) 0.75
Multiple Psychopharmacological Effects of the Traditional Japanese Kampo Medicine Yokukansan, and the Brain Regions it Affects. Front Pharmacol (2017) 0.75
Yokukansan enhances the proliferation of B65 neuroblastoma. J Tradit Complement Med (2016) 0.75
Cellular Pharmacological Effects of the Traditional Japanese Kampo Medicine Yokukansan on Brain Cells. Front Pharmacol (2017) 0.75
Conformational landscape of cytochrome c folding studied by microsecond-resolved small-angle x-ray scattering. Proc Natl Acad Sci U S A (2002) 2.19
Generation of rejuvenated antigen-specific T cells by reprogramming to pluripotency and redifferentiation. Cell Stem Cell (2013) 2.01
Laparoscopic liver resection of hepatocellular carcinoma. Am J Surg (2005) 2.00
Disease-specific analyses of unrelated cord blood transplantation compared with unrelated bone marrow transplantation in adult patients with acute leukemia. Blood (2008) 1.86
Direct observation of Abeta amyloid fibril growth and inhibition. J Mol Biol (2004) 1.82
Regulation of aged humoral immune defense against pneumococcal bacteria by IgM memory B cell. J Immunol (2005) 1.71
3D structure of amyloid protofilaments of beta2-microglobulin fragment probed by solid-state NMR. Proc Natl Acad Sci U S A (2006) 1.70
Nucleotide-binding oligomerization domain 1 mediates recognition of Clostridium difficile and induces neutrophil recruitment and protection against the pathogen. J Immunol (2011) 1.63
Collapse and search dynamics of apomyoglobin folding revealed by submillisecond observations of alpha-helical content and compactness. Proc Natl Acad Sci U S A (2004) 1.56
Pretransplant administration of imatinib for allo-HSCT in patients with BCR-ABL-positive acute lymphoblastic leukemia. Blood (2014) 1.55
The immunosuppressive drug mizoribine directly prevents podocyte injury in puromycin aminonucleoside nephrosis. Nephron Exp Nephrol (2010) 1.51
National institutes of Health Chronic Prostatitis Symptom Index for Japanese men. Urology (2002) 1.48
Verapamil eliminates the hierarchical nature of activation frequencies from the pulmonary veins to the atria during paroxysmal atrial fibrillation. Heart Rhythm (2010) 1.39
Periodic fever and apoptosis of accumulated neutrophils in familial mediterranean fever: comment on the article by Touitou et al. Arthritis Rheum (2007) 1.38
Nationwide survey of urogenital tuberculosis in Japan. Int J Urol (2014) 1.38
Neuromelanin magnetic resonance imaging of locus ceruleus and substantia nigra in Parkinson's disease. Neuroreport (2006) 1.37
Specific collapse followed by slow hydrogen-bond formation of beta-sheet in the folding of single-chain monellin. Proc Natl Acad Sci U S A (2005) 1.26
Nuclear magnetic resonance characterization of the refolding intermediate of beta2-microglobulin trapped by non-native prolyl peptide bond. J Mol Biol (2005) 1.25
Transitions in oral and intestinal microflora composition and innate immune receptor-dependent stimulation during mouse development. Infect Immun (2009) 1.25
SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians. PLoS One (2013) 1.23
NO reduction by nitric-oxide reductase from denitrifying bacterium Pseudomonas aeruginosa: characterization of reaction intermediates that appear in the single turnover cycle. J Biol Chem (2004) 1.20
Pharmacological, pharmacokinetic and clinical properties of olopatadine hydrochloride, a new antiallergic drug. Jpn J Pharmacol (2002) 1.18
Hierarchical folding mechanism of apomyoglobin revealed by ultra-fast H/D exchange coupled with 2D NMR. Proc Natl Acad Sci U S A (2008) 1.17
Seeding-dependent propagation and maturation of amyloid fibril conformation. J Mol Biol (2005) 1.15
A new way to degrade heme: the Mycobacterium tuberculosis enzyme MhuD catalyzes heme degradation without generating CO. J Biol Chem (2013) 1.14
Comparison of unrelated cord blood transplantation and HLA-mismatched unrelated bone marrow transplantation for adults with leukemia. Biol Blood Marrow Transplant (2011) 1.10
Dendritic cell-specific ablation of the protein tyrosine phosphatase Shp1 promotes Th1 cell differentiation and induces autoimmunity. J Immunol (2012) 1.09
Hybrid procedures combining conventional and thoracic endovascular aortic repair for thoracic aortic aneurysms. Surg Today (2011) 1.07
Direct observation of the multistep helix formation of poly-L-glutamic acids. J Am Chem Soc (2002) 1.07
Development of a technique for the investigation of folding dynamics of single proteins for extended time periods. Proc Natl Acad Sci U S A (2007) 1.07
Roles of the proximal hydrogen bonding network in cytochrome P450cam-catalyzed oxygenation. J Am Chem Soc (2002) 1.06
The impact of inflammation on the pathogenesis and prognosis of ischemic stroke. J Neurol Sci (2008) 1.06
Unrelated cord blood transplantation for adult patients with de novo acute myeloid leukemia. Blood (2003) 1.05
Genetic profiles of fluoroquinolone-resistant Escherichia coli isolates obtained from patients with cystitis: phylogeny, virulence factors, PAIusp subtypes, and mutation patterns. J Clin Microbiol (2009) 1.05
Spatially selective hormonal control of RAP2.6L and ANAC071 transcription factors involved in tissue reunion in Arabidopsis. Proc Natl Acad Sci U S A (2011) 1.05
Serum C-reactive protein levels can be used to predict future ischemic stroke and mortality in Japanese men from the general population. Atherosclerosis (2008) 1.03
Central nervous system relapse of leukemia after allogeneic hematopoietic stem cell transplantation. Biol Blood Marrow Transplant (2008) 1.02
Time-resolved small-angle X-ray scattering investigation of the folding dynamics of heme oxygenase: implication of the scaling relationship for the submillisecond intermediates of protein folding. J Mol Biol (2006) 1.00
Spinal stenosis in grade I degenerative lumbar spondylolisthesis: a comparative study of outcomes following laminoplasty and laminectomy with instrumented spinal fusion. J Orthop Sci (2005) 0.99
The RIKEN integrated database of mammals. Nucleic Acids Res (2010) 0.99
Multidrug-resistant Pseudomonas aeruginosa isolated from the urine of patients with urinary tract infection. J Infect Chemother (2002) 0.99
Molecular and clinical risk factors for recurrence of skull base chordomas: gain on chromosome 2p, expression of brachyury, and lack of irradiation negatively correlate with patient prognosis. J Neuropathol Exp Neurol (2013) 0.99
NMR study on the structural changes of cytochrome P450cam upon the complex formation with putidaredoxin. Functional significance of the putidaredoxin-induced structural changes. J Biol Chem (2003) 0.99
The efficacy of prostaglandin E1 derivative in patients with lumbar spinal stenosis. Spine (Phila Pa 1976) (2009) 0.99
Cytomegalovirus infection following unrelated cord blood transplantation for adult patients: a single institute experience in Japan. Br J Haematol (2003) 0.98
Impact of cytogenetics on outcome of stem cell transplantation for acute myeloid leukemia in first remission: a large-scale retrospective analysis of data from the Japan Society for Hematopoietic Cell Transplantation. Int J Hematol (2004) 0.98
Hematopoietic stem cell transplantation for core binding factor acute myeloid leukemia: t(8;21) and inv(16) represent different clinical outcomes. Blood (2009) 0.98
Anti-invasive and metastatic activities of evodiamine. Biol Pharm Bull (2002) 0.98
Neutrophil-mediated inflammation in respiratory syncytial viral bronchiolitis. Pediatr Int (2005) 0.97
Phase I study of autologous tumor vaccines transduced with the GM-CSF gene in four patients with stage IV renal cell cancer in Japan: clinical and immunological findings. Mol Ther (2004) 0.97
Laparoscopic hepatectomy for liver tumors: proposals for standardization. J Hepatobiliary Pancreat Surg (2009) 0.96
Unrelated cord blood transplantation after myeloablative conditioning in adults with acute myelogenous leukemia. Biol Blood Marrow Transplant (2008) 0.96
A serotonin 5-HT1A receptor agonist prevents behavioral sensitization to L-DOPA in a rodent model of Parkinson's disease. Neurosci Res (2005) 0.96
Microbe-I: fungal biota analyses of the Japanese experimental module KIBO of the International Space Station before launch and after being in orbit for about 460 days. Microbiol Immunol (2011) 0.95
Diffusion changes in a tumor and peritumoral tissue after stereotactic irradiation for brain tumors: possible prediction of treatment response. J Comput Assist Tomogr (2006) 0.95
Impact of human leucocyte antigen mismatch on graft-versus-host disease and graft failure after reduced intensity conditioning allogeneic haematopoietic stem cell transplantation from related donors. Br J Haematol (2005) 0.95
Specifically collapsed intermediate in the early stage of the folding of ribonuclease A. J Mol Biol (2005) 0.95
Chronic graft-versus-host disease following umbilical cord blood transplantation: retrospective survey involving 1072 patients in Japan. Blood (2008) 0.95
Therapeutic outcome of multifocal Langerhans cell histiocytosis in adults treated with the Special C regimen formulated by the Japan LCH Study Group. Int J Hematol (2012) 0.95
Time-resolved small-angle X-ray scattering study of the folding dynamics of barnase. J Mol Biol (2010) 0.95
Effect of conditioning regimen on the outcome of bone marrow transplantation from an unrelated donor. Biol Blood Marrow Transplant (2005) 0.94
Different effects of HLA disparity on transplant outcomes after single-unit cord blood transplantation between pediatric and adult patients with leukemia. Haematologica (2013) 0.94
Serum amyloid A3 binds MD-2 to activate p38 and NF-κB pathways in a MyD88-dependent manner. J Immunol (2013) 0.93
Quantitative analysis of the cutaneous Malassezia microbiota in 770 healthy Japanese by age and gender using a real-time PCR assay. Med Mycol (2010) 0.93
Neutrophil elastase and cancer. Surg Oncol (2007) 0.93
Bacterial colonization on intraluminal surface of urethral catheter. Urology (2005) 0.93
Ischemic lesions related to cerebral angiography: Evaluation by diffusion weighted MR imaging. Neuroradiology (2002) 0.93
Prognostic significance of immunoreactive neutrophil elastase in human breast cancer: long-term follow-up results in 313 patients. Neoplasia (2007) 0.92
Multiple Scedosporium apiospermum abscesses in a woman survivor of a tsunami in northeastern Japan: a case report. J Med Case Rep (2011) 0.92
Use of neuromelanin-sensitive MRI to distinguish schizophrenic and depressive patients and healthy individuals based on signal alterations in the substantia nigra and locus ceruleus. Biol Psychiatry (2008) 0.92
Activation of hydrogen peroxide in horseradish peroxidase occurs within approximately 200 micro s observed by a new freeze-quench device. Biophys J (2003) 0.92
Incidence, risk factors and outcomes of bronchiolitis obliterans after allogeneic stem cell transplantation. Int J Hematol (2011) 0.92
Dehydration of main-chain amides in the final folding step of single-chain monellin revealed by time-resolved infrared spectroscopy. Proc Natl Acad Sci U S A (2008) 0.91
Prehypertension subtype with elevated C-reactive protein: risk of ischemic stroke in a general Japanese population. Am J Hypertens (2010) 0.91
Phenotypic and functional alterations of peripheral blood monocytes in neutrophil-specific granule deficiency. J Leukoc Biol (2003) 0.91
[Tandospirone citrate, a selective 5-HT1A agonist, alleviates L-DOPA-induced dyskinesia in patients with Parkinson's disease]. No To Shinkei (2002) 0.91
Aβ43 is the earliest-depositing Aβ species in APP transgenic mouse brain and is converted to Aβ41 by two active domains of ACE. Am J Pathol (2013) 0.90
Dietary supplementation of fermented soybean, natto, suppresses intimal thickening and modulates the lysis of mural thrombi after endothelial injury in rat femoral artery. Life Sci (2003) 0.90
Serum low-density lipoprotein to high-density lipoprotein ratio as a predictor of future acute myocardial infarction among men in a 2.7-year cohort study of a Japanese northern rural population. J Atheroscler Thromb (2010) 0.90
Feasibility of reduced-intensity cord blood transplantation as salvage therapy for graft failure: results of a nationwide survey of adult patients. Biol Blood Marrow Transplant (2010) 0.90
Nationwide surveillance of bacterial pathogens from patients with acute uncomplicated cystitis conducted by the Japanese surveillance committee during 2009 and 2010: antimicrobial susceptibility of Escherichia coli and Staphylococcus saprophyticus. J Infect Chemother (2013) 0.90
Effects of edaravone on muscle atrophy and locomotor function in patients with ischemic stroke: a randomized controlled pilot study. Drugs R D (2010) 0.89
Increased mitochondrial oxidative damage in patients with sporadic amyotrophic lateral sclerosis. J Neurol Sci (2007) 0.89
Thalidomide for treatment of intestinal involvement of juvenile-onset Behçet disease. Inflamm Bowel Dis (2008) 0.89
Varicella-zoster virus infection in adult patients after unrelated cord blood transplantation: a single institute experience in Japan. Br J Haematol (2003) 0.89
Bystander transfer of functional human CD40 ligand from gene-modified fibroblasts to B-chronic lymphocytic leukemia cells. Hum Gene Ther (2003) 0.89
Telomerase activity and human telomerase reverse transcriptase mRNA expression are correlated with clinical aggressiveness in soft tissue tumors. Cancer (2002) 0.89
Varicella-zoster virus encephalitis in a patient undergoing unrelated cord blood transplantation for myelodysplastic syndrome-overt leukemia. Int J Hematol (2006) 0.89
Sensitivities of major causative organisms isolated from patients with acute uncomplicated cystitis against various antibacterial agents: results of subanalysis based on the presence of menopause. J Infect Chemother (2012) 0.89
Membrane-anchored CD14 is important for induction of interleukin-8 by lipopolysaccharide and peptidoglycan in uroepithelial cells. Clin Diagn Lab Immunol (2004) 0.89
Action potential characteristics in the sinus venosa of patients with and without atrial flutter. Circ J (2009) 0.88
Is seminal vesiculitis a discrete disease entity? Clinical and microbiological study of seminal vesiculitis in patients with acute epididymitis. J Urol (2004) 0.88
Solvation and desolvation dynamics in apomyoglobin folding monitored by time-resolved infrared spectroscopy. J Mol Biol (2007) 0.88
Systemic inflammatory response syndrome in open versus laparoscopic adrenalectomy. Urology (2004) 0.88
Effectiveness of laparoscopic subtotal cholecystectomy: perioperative and long-term postoperative results. Hepatogastroenterology (2013) 0.88
Clinical diagnosis of vascular dementia. J Neurol Sci (2007) 0.88
Novel locus for benign hereditary chorea with adult onset maps to chromosome 8q21.3 q23.3. Brain (2007) 0.88