Published in J Addict Res Ther on December 24, 2011
Role of corticostriatal circuits in context-induced reinstatement of drug seeking. Brain Res (2014) 0.96
The Plasticity of Extinction: Contribution of the Prefrontal Cortex in Treating Addiction through Inhibitory Learning. Front Psychiatry (2013) 0.94
Positive Allosteric Modulation of mGluR5 Accelerates Extinction Learning but Not Relearning Following Methamphetamine Self-Administration. Front Pharmacol (2012) 0.88
Potentiating mGluR5 function with a positive allosteric modulator enhances adaptive learning. Learn Mem (2013) 0.86
Context-induced reinstatement of methamphetamine seeking is associated with unique molecular alterations in Fos-expressing dorsolateral striatum neurons. J Neurosci (2015) 0.84
The metabotropic glutamate 5 receptor modulates extinction and reinstatement of methamphetamine-seeking in mice. PLoS One (2013) 0.83
Perirhinal Cortex mGlu5 Receptor Activation Reduces Relapse to Methamphetamine Seeking by Restoring Novelty Salience. Neuropsychopharmacology (2015) 0.80
Positive or negative allosteric modulation of metabotropic glutamate receptor 5 (mGluR5) does not alter expression of behavioral sensitization to methamphetamine. F1000Res (2013) 0.77
Effects of menthol and its interaction with nicotine-conditioned cue on nicotine-seeking behavior in rats. Psychopharmacology (Berl) (2017) 0.75
Context and behavioral processes in extinction. Learn Mem (2004) 6.99
Context, ambiguity, and unlearning: sources of relapse after behavioral extinction. Biol Psychiatry (2002) 6.67
Limbic activation during cue-induced cocaine craving. Am J Psychiatry (1999) 6.66
Applying extinction research and theory to cue-exposure addiction treatments. Addiction (2002) 5.47
Drug addiction as a pathology of staged neuroplasticity. Neuropsychopharmacology (2007) 3.73
Extinction circuits for fear and addiction overlap in prefrontal cortex. Learn Mem (2009) 3.62
The role of the dorsomedial prefrontal cortex, basolateral amygdala, and dorsal hippocampus in contextual reinstatement of cocaine seeking in rats. Neuropsychopharmacology (2005) 3.28
Review. Context-induced relapse to drug seeking: a review. Philos Trans R Soc Lond B Biol Sci (2008) 2.98
A novel selective positive allosteric modulator of metabotropic glutamate receptor subtype 5 has in vivo activity and antipsychotic-like effects in rat behavioral models. J Pharmacol Exp Ther (2004) 2.83
Renewal of drug seeking by contextual cues after prolonged extinction in rats. Behav Neurosci (2002) 2.76
Group 1 mGluR-dependent synaptic long-term depression: mechanisms and implications for circuitry and disease. Neuron (2010) 2.67
N-acetylcysteine reduces extinction responding and induces enduring reductions in cue- and heroin-induced drug-seeking. Biol Psychiatry (2007) 1.90
d-Cycloserine facilitates extinction of a cocaine-induced conditioned place preference. Behav Brain Res (2006) 1.90
Targeting extinction and reconsolidation mechanisms to combat the impact of drug cues on addiction. Neuropharmacology (2008) 1.84
ADX47273 [S-(4-fluoro-phenyl)-{3-[3-(4-fluoro-phenyl)-[1,2,4]-oxadiazol-5-yl]-piperidin-1-yl}-methanone]: a novel metabotropic glutamate receptor 5-selective positive allosteric modulator with preclinical antipsychotic-like and procognitive activities. J Pharmacol Exp Ther (2008) 1.81
mGluR5 positive allosteric modulators facilitate both hippocampal LTP and LTD and enhance spatial learning. Neuropsychopharmacology (2009) 1.80
mGluR5 has a critical role in inhibitory learning. J Neurosci (2009) 1.76
Pharmacological approaches to methamphetamine dependence: a focused review. Br J Clin Pharmacol (2010) 1.71
The infralimbic cortex regulates the consolidation of extinction after cocaine self-administration. Learn Mem (2010) 1.66
Approaches to the development of medications for the treatment of methamphetamine dependence. Addiction (2007) 1.56
Abuse of amphetamines and structural abnormalities in the brain. Ann N Y Acad Sci (2008) 1.54
Glutamate receptors in extinction and extinction-based therapies for psychiatric illness. Neuropsychopharmacology (2010) 1.51
D-cycloserine deters reacquisition of cocaine self-administration by augmenting extinction learning. Neuropsychopharmacology (2010) 1.46
Positive allosteric modulation of mGluR5 receptors facilitates extinction of a cocaine contextual memory. Biol Psychiatry (2008) 1.43
Interaction of N-methyl-D-aspartate and group 5 metabotropic glutamate receptors on behavioral flexibility using a novel operant set-shift paradigm. Behav Pharmacol (2008) 1.43
Metabotropic glutamate receptor-mediated long-term depression: molecular mechanisms. Pharmacol Rev (2009) 1.40
Dose-dependent effect of CDPPB, the mGluR5 positive allosteric modulator, on recognition memory is associated with GluR1 and CREB phosphorylation in the prefrontal cortex and hippocampus. Neuropharmacology (2009) 1.37
Methamphetamine self-administration and voluntary exercise have opposing effects on medial prefrontal cortex gliogenesis. J Neurosci (2007) 1.32
D-cycloserine reduces the context specificity of pavlovian extinction of cocaine cues through actions in the nucleus accumbens. J Neurosci (2010) 1.30
Corticolimbic dysregulation and chronic methamphetamine abuse. Addiction (2007) 1.28
Addiction as a pathology in prefrontal cortical regulation of corticostriatal habit circuitry. Neurotox Res (2008) 1.26
Loss of object recognition memory produced by extended access to methamphetamine self-administration is reversed by positive allosteric modulation of metabotropic glutamate receptor 5. Neuropsychopharmacology (2010) 1.25
D-cycloserine accelerates the extinction of cocaine-induced conditioned place preference in C57bL/c mice. Behav Brain Res (2008) 1.20
Extinction of drug- and withdrawal-paired cues in animal models: relevance to the treatment of addiction. Neurosci Biobehav Rev (2010) 1.19
Role of the prefrontal cortex and nucleus accumbens in reinstating methamphetamine seeking. Eur J Neurosci (2010) 1.17
Increasing the efficacy of cue exposure treatment in preventing relapse of addictive behavior. Addict Behav (2003) 1.14
mGluR5 positive allosteric modulation enhances extinction learning following cocaine self-administration. Behav Neurosci (2011) 1.10
Stimulant abuse: pharmacology, cocaine, methamphetamine, treatment, attempts at pharmacotherapy. Prim Care (2011) 1.09
Methamphetamine self-administration produces attentional set-shifting deficits and alters prefrontal cortical neurophysiology in rats. Biol Psychiatry (2010) 1.08
Metabotropic glutamate receptor subtype 5 antagonism in learning and memory. Eur J Pharmacol (2010) 1.07
Activation of type 5 metabotropic glutamate receptors attenuates deficits in cognitive flexibility induced by NMDA receptor blockade. Eur J Pharmacol (2010) 1.07
Cognitive enhancers for facilitating drug cue extinction: insights from animal models. Pharmacol Biochem Behav (2011) 1.00
Positive allosteric modulators of type 5 metabotropic glutamate receptors (mGluR5) and their therapeutic potential for the treatment of CNS disorders. Molecules (2011) 0.99
Neurologic manifestations of chronic methamphetamine abuse. Neurol Clin (2011) 0.96
Glutamatergic targets for enhancing extinction learning in drug addiction. Curr Neuropharmacol (2010) 0.95
D-cycloserine facilitates extinction of cocaine self-administration in rats. Synapse (2011) 0.94
Effects of a positive allosteric modulator of mGluR5 ADX47273 on conditioned avoidance response and PCP-induced hyperlocomotion in the rat as models for schizophrenia. Pharmacol Biochem Behav (2009) 0.92
Functional interaction of mGlu5 and NMDA receptors in aversive learning in rats. Neurobiol Learn Mem (2010) 0.90
Pharmacological enhancement of drug cue extinction learning: translational challenges. Ann N Y Acad Sci (2011) 0.90
Brain region-selective cellular redistribution of mGlu5 but not GABA(B) receptors following methamphetamine-induced associative learning. Synapse (2011) 0.86
N-Acetylcysteine reverses cocaine-induced metaplasticity. Nat Neurosci (2009) 3.49
Glutamatergic substrates of drug addiction and alcoholism. Biochem Pharmacol (2007) 3.06
Inhibition of aldehyde dehydrogenase-2 suppresses cocaine seeking by generating THP, a cocaine use-dependent inhibitor of dopamine synthesis. Nat Med (2010) 1.84
mGluR5 positive allosteric modulators facilitate both hippocampal LTP and LTD and enhance spatial learning. Neuropsychopharmacology (2009) 1.80
Potent rewarding and reinforcing effects of the synthetic cathinone 3,4-methylenedioxypyrovalerone (MDPV). Addict Biol (2012) 1.64
mGluR5 antagonism attenuates methamphetamine reinforcement and prevents reinstatement of methamphetamine-seeking behavior in rats. Neuropsychopharmacology (2008) 1.57
Positive allosteric modulation of mGluR5 receptors facilitates extinction of a cocaine contextual memory. Biol Psychiatry (2008) 1.43
The mGluR5 antagonist MPEP reduces the conditioned rewarding effects of cocaine but not other drugs of abuse. Synapse (2003) 1.41
Glutamatergic medications for the treatment of drug and behavioral addictions. Pharmacol Biochem Behav (2011) 1.38
Ethanol facilitates glutamatergic transmission to dopamine neurons in the ventral tegmental area. Neuropsychopharmacology (2008) 1.32
Decreased anxiety-like behavior, reduced stress hormones, and neurosteroid supersensitivity in mice lacking protein kinase Cepsilon. J Clin Invest (2002) 1.31
Chronic alcohol exposure alters behavioral and synaptic plasticity of the rodent prefrontal cortex. PLoS One (2012) 1.28
Loss of object recognition memory produced by extended access to methamphetamine self-administration is reversed by positive allosteric modulation of metabotropic glutamate receptor 5. Neuropsychopharmacology (2010) 1.25
Anxiogenic and aversive effects of corticotropin-releasing factor (CRF) in the bed nucleus of the stria terminalis in the rat: role of CRF receptor subtypes. Psychopharmacology (Berl) (2006) 1.24
Suppression of heavy drinking and alcohol seeking by a selective ALDH-2 inhibitor. Alcohol Clin Exp Res (2009) 1.13
Novel allosteric agonists of M1 muscarinic acetylcholine receptors induce brain region-specific responses that correspond with behavioral effects in animal models. J Neurosci (2012) 1.13
Role of protein kinase C epsilon (PKCvarepsilon) in the reduction of ethanol reinforcement due to mGluR5 antagonism in the nucleus accumbens shell. Psychopharmacology (Berl) (2009) 1.11
The Reinforcing and Rewarding Effects of Methylone, a Synthetic Cathinone Commonly Found in "Bath Salts" J Addict Res Ther (2012) 1.10
mGluR5 positive allosteric modulation enhances extinction learning following cocaine self-administration. Behav Neurosci (2011) 1.10
The glucocorticoid receptor antagonist mifepristone reduces ethanol intake in rats under limited access conditions. Psychoneuroendocrinology (2004) 1.06
mGluR5 receptors in the basolateral amygdala and nucleus accumbens regulate cue-induced reinstatement of ethanol-seeking behavior. Pharmacol Biochem Behav (2012) 1.05
The Effects of Maternal Separation on Adult Methamphetamine Self-Administration, Extinction, Reinstatement, and MeCP2 Immunoreactivity in the Nucleus Accumbens. Front Psychiatry (2013) 1.03
Alcohol-seeking behavior is associated with increased glutamate transmission in basolateral amygdala and nucleus accumbens as measured by glutamate-oxidase-coated biosensors. Addict Biol (2010) 1.02
Reinstatement of ethanol-seeking behavior following intravenous self-administration in Wistar rats. Alcohol Clin Exp Res (2007) 1.01
Chronic alcohol disrupts dopamine receptor activity and the cognitive function of the medial prefrontal cortex. J Neurosci (2014) 0.99
Positive allosteric modulators of type 5 metabotropic glutamate receptors (mGluR5) and their therapeutic potential for the treatment of CNS disorders. Molecules (2011) 0.99
Attenuation of methamphetamine seeking by the mGluR2/3 agonist LY379268 in rats with histories of restricted and escalated self-administration. Neuropharmacology (2012) 0.97
A role for mGluR5 receptors in intravenous methamphetamine self-administration. Ann N Y Acad Sci (2008) 0.95
Ethanol exposure during development reduces resident aggression and testosterone in rats. Physiol Behav (2005) 0.93
Effect of the mGluR5 antagonist 6-methyl-2-(phenylethynyl)pyridine (MPEP) on the acute locomotor stimulant properties of cocaine, D-amphetamine, and the dopamine reuptake inhibitor GBR12909 in mice. Psychopharmacology (Berl) (2004) 0.92
The anti-relapse compound acamprosate inhibits the development of a conditioned place preference to ethanol and cocaine but not morphine. Br J Pharmacol (2003) 0.92
Attenuation of reinstatement of methamphetamine-, sucrose-, and food-seeking behavior in rats by fenobam, a metabotropic glutamate receptor 5 negative allosteric modulator. Psychopharmacology (Berl) (2012) 0.92
Positive Allosteric Modulation of mGluR5 Accelerates Extinction Learning but Not Relearning Following Methamphetamine Self-Administration. Front Pharmacol (2012) 0.88
Effects of adolescent exposure to cocaine on locomotor activity and extracellular dopamine and glutamate levels in nucleus accumbens of DBA/2J mice. Brain Res (2007) 0.88
The corticotropin-releasing factor/urocortin system and alcohol. Alcohol Clin Exp Res (2002) 0.88
Pharmacotherapies for alcoholism: the old and the new. CNS Neurol Disord Drug Targets (2010) 0.87
Role of the endogenous opioid system on the neuropsychopharmacological effects of ethanol: new insights about an old question. Alcohol Clin Exp Res (2005) 0.86
Acamprosate attenuates cocaine- and cue-induced reinstatement of cocaine-seeking behavior in rats. Psychopharmacology (Berl) (2007) 0.86
Safety and efficacy of acamprosate for the treatment of alcohol dependence. Subst Abuse (2013) 0.86
Ethanol consumption patterns and conditioned place preference in mice lacking preproenkephalin. Neurosci Lett (2002) 0.85
The safety of disulfiram for the treatment of alcohol and cocaine dependence in randomized clinical trials: guidance for clinical practice. Expert Opin Drug Saf (2008) 0.85
Changes in extracellular levels of glutamate in the nucleus accumbens after ethanol-induced behavioral sensitization in adolescent and adult mice. Alcohol (2011) 0.83
mGluR5 positive allosteric modulation and its effects on MK-801 induced set-shifting impairments in a rat operant delayed matching/non-matching-to-sample task. Psychopharmacology (Berl) (2014) 0.82
Similar ethanol drinking in adolescent and adult C57BL/6J mice after chronic ethanol exposure and withdrawal. Alcohol Clin Exp Res (2013) 0.81
Ontogenetic quinpirole treatments produce spatial memory deficits and enhance skilled reaching in adult rats. Pharmacol Biochem Behav (2002) 0.81
Intracranial stereotaxic cannulation for development of orthotopic glioblastoma allograft in Sprague-Dawley rats and histoimmunopathological characterization of the brain tumor. Neurochem Res (2007) 0.80
Constitutive knockout of kalirin-7 leads to increased rates of cocaine self-administration. Mol Pharmacol (2013) 0.80
Differential Modulation of Thresholds for Intracranial Self-Stimulation by mGlu5 Positive and Negative Allosteric Modulators: Implications for Effects on Drug Self-Administration. Front Pharmacol (2012) 0.80
Investigating Methamphetamine Craving Using the Extinction-Reinstatement Model in the Rat. J Addict Res Ther (2011) 0.80
Neurochemical and neurostructural plasticity in alcoholism. ACS Chem Neurosci (2012) 0.79
Ethanol pre-exposure during adolescence or adulthood increases ethanol intake but ethanol-induced conditioned place preference is enhanced only when pre-exposure occurs in adolescence. Dev Psychobiol (2012) 0.79
Combined antiretroviral therapy reduces brain viral load and pathological features of HIV encephalitis in a mouse model. J Neurovirol (2014) 0.79
Early life stress and chronic variable stress in adulthood interact to influence methamphetamine self-administration in male rats. Behav Pharmacol (2016) 0.79
Increases in doublecortin immunoreactivity in the dentate gyrus following extinction of heroin-seeking behavior. Neural Plast (2012) 0.77
mGluR5 Positive and Negative Allosteric Modulators Differentially Affect Dendritic Spine Density and Morphology in the Prefrontal Cortex. CNS Neurol Disord Drug Targets (2015) 0.77
Transcriptional profiling of the rat frontal cortex following administration of the mGlu5 receptor antagonists MPEP and MTEP. Eur J Pharmacol (2008) 0.77
NMDA Receptor Modulators in the Treatment of Drug Addiction. Pharmaceuticals (Basel) (2013) 0.77
Early-life stress interactions with the epigenome: potential mechanisms driving vulnerability toward psychiatric illness. Behav Pharmacol (2014) 0.77
mGlu receptors and drug addiction. Wiley Interdiscip Rev Membr Transp Signal (2012) 0.76
A microdialysis study of extracellular levels of acamprosate and naltrexone in the rat brain following acute and repeated administration. Addict Biol (2008) 0.76
Neuropeptide systems and schizophrenia. CNS Neurol Disord Drug Targets (2013) 0.76
The development of acamprosate as a treatment against alcohol relapse. Expert Opin Drug Discov (2014) 0.76
Extinction learning and adult neurogenesis. Neuropsychopharmacology (2011) 0.75
The effect of litter separation on methamphetamine-conditioned place preference in post-partum dams. Behav Pharmacol (2017) 0.75