The three human monocyte subsets: implications for health and disease.

PubWeight™: 2.08‹?› | Rank: Top 2%

🔗 View Article (PMID 22430559)

Published in Immunol Res on September 01, 2012

Authors

Kok Loon Wong1, Wei Hseun Yeap, June Jing Yi Tai, Siew Min Ong, Truong Minh Dang, Siew Cheng Wong

Author Affiliations

1: Singapore Immunology Network, Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, #04/04 Immunos, Biopolis, Singapore.

Articles citing this

Development and function of human innate immune cells in a humanized mouse model. Nat Biotechnol (2014) 2.28

From Monocytes to M1/M2 Macrophages: Phenotypical vs. Functional Differentiation. Front Immunol (2014) 2.03

Toward a refined definition of monocyte subsets. Front Immunol (2013) 1.45

Modulation of Immune Responses by Extracellular Vesicles From Retinal Pigment Epithelium. Invest Ophthalmol Vis Sci (2016) 1.37

An optimized protocol for human M2 macrophages using M-CSF and IL-4/IL-10/TGF-β yields a dominant immunosuppressive phenotype. Scand J Immunol (2014) 1.04

IL-4/IL-13-dependent and independent expression of miR-124 and its contribution to M2 phenotype of monocytic cells in normal conditions and during allergic inflammation. PLoS One (2013) 1.01

Blood Monocytes and Their Subsets: Established Features and Open Questions. Front Immunol (2015) 0.99

Sources of heterogeneity in human monocyte subsets. Immunol Lett (2013) 0.99

Compartmentalization of innate immune responses in the central nervous system during cryptococcal meningitis/HIV coinfection. AIDS (2014) 0.98

Non-Classical monocytes display inflammatory features: Validation in Sepsis and Systemic Lupus Erythematous. Sci Rep (2015) 0.97

Human and Mouse Mononuclear Phagocyte Networks: A Tale of Two Species? Front Immunol (2015) 0.95

Characteristic repartition of monocyte subsets as a diagnostic signature of chronic myelomonocytic leukemia. Blood (2015) 0.93

Clinical significance of monocyte heterogeneity. Clin Transl Med (2015) 0.90

Pregnancy and preeclampsia affect monocyte subsets in humans and rats. PLoS One (2012) 0.89

Visualisation of chicken macrophages using transgenic reporter genes: insights into the development of the avian macrophage lineage. Development (2014) 0.86

Prenatal immunologic predictors of postpartum depressive symptoms: a prospective study for potential diagnostic markers. Eur Arch Psychiatry Clin Neurosci (2014) 0.85

Hemin controls T cell polarization in sickle cell alloimmunization. J Immunol (2014) 0.85

Impact of brief exercise on circulating monocyte gene and microRNA expression: implications for atherosclerotic vascular disease. Brain Behav Immun (2014) 0.85

Profiling leucocyte subsets in tuberculosis-diabetes co-morbidity. Immunology (2015) 0.85

Untreated stage IV melanoma patients exhibit abnormal monocyte phenotypes and decreased functional capacity. Cancer Immunol Res (2013) 0.84

Functional phenotype of synovial monocytes modulating inflammatory T-cell responses in rheumatoid arthritis (RA). PLoS One (2014) 0.84

Monocyte expression and soluble levels of the haemoglobin receptor (CD163/sCD163) and the mannose receptor (MR/sMR) in septic and critically ill non-septic ICU patients. PLoS One (2014) 0.84

Traumatic Brain Injury and Peripheral Immune Suppression: Primer and Prospectus. Front Neurol (2015) 0.83

Infliximab therapy increases the frequency of circulating CD16(+) monocytes and modifies macrophage cytokine response to bacterial infection. Clin Exp Immunol (2014) 0.83

Tuberculosis is associated with expansion of a motile, permissive and immunomodulatory CD16(+) monocyte population via the IL-10/STAT3 axis. Cell Res (2015) 0.83

Impaired NLRP3 inflammasome activity during fetal development regulates IL-1β production in human monocytes. Eur J Immunol (2014) 0.83

Circulating monocytes: an appropriate model for bone-related study. Osteoporos Int (2015) 0.83

Prolonged proinflammatory cytokine production in monocytes modulated by interleukin 10 after influenza vaccination in older adults. J Infect Dis (2014) 0.81

Phenotypic and functional analysis of monocyte populations in cattle peripheral blood identifies a subset with high endocytic and allogeneic T-cell stimulatory capacity. Vet Res (2015) 0.80

Immune cells subpopulations in cerebrospinal fluid and peripheral blood of patients with Aneurysmal Subarachnoid Hemorrhage. Springerplus (2015) 0.80

Myeloid-Derived Suppressor Cells as an Immune Parameter in Patients with Concurrent Sunitinib and Stereotactic Body Radiotherapy. Clin Cancer Res (2015) 0.80

Altered Peripheral Blood Monocyte Phenotype and Function in Chronic Liver Disease: Implications for Hepatic Recruitment and Systemic Inflammation. PLoS One (2016) 0.80

Monocyte Heterogeneity: Consequences for Monocyte-Derived Immune Cells. J Immunol Res (2016) 0.80

Circulating CD14brightCD16+ 'intermediate' monocytes exhibit enhanced parasite pattern recognition in human helminth infection. PLoS Negl Trop Dis (2014) 0.79

Transcriptomic profiling of the development of the inflammatory response in human monocytes in vitro. PLoS One (2014) 0.79

Non-Classical Monocytes and Monocyte Chemoattractant Protein-1 (MCP-1) Correlate with Coronary Artery Calcium Progression in Chronically HIV-1 Infected Adults on Stable Antiretroviral Therapy. PLoS One (2016) 0.79

CD16 expression on monocytes in healthy individuals but not schistosome-infected patients is positively associated with levels of parasite-specific IgG and IgG1. PLoS Negl Trop Dis (2014) 0.79

Loss of CCR2 expressing non-classical monocytes are associated with cognitive impairment in antiretroviral therapy-naïve HIV-infected Thais. J Neuroimmunol (2015) 0.79

Interlesional diversity of T cell receptors in melanoma with immune checkpoints enriched in tissue-resident memory T cells. JCI Insight (2016) 0.78

Human monocyte subsets at homeostasis and their perturbation in numbers and function in filarial infection. Infect Immun (2014) 0.78

CD40 in coronary artery disease: a matter of macrophages? Basic Res Cardiol (2016) 0.78

Do not judge a cell by its cover-diversity of CNS resident, adjoining and infiltrating myeloid cells in inflammation. Semin Immunopathol (2015) 0.78

Orosomucoid 1 drives opportunistic infections through the polarization of monocytes to the M2b phenotype. Cytokine (2015) 0.78

Parallel Aspects of the Microenvironment in Cancer and Autoimmune Disease. Mediators Inflamm (2016) 0.78

Selective expansion of pro-inflammatory chemokine CCL2-loaded CD14+CD16+ monocytes subset in HIV-infected therapy naïve individuals. J Clin Immunol (2012) 0.78

Changes in T-Cell and Monocyte Phenotypes In Vitro by Schistosoma mansoni Antigens in Cutaneous Leishmaniasis Patients. J Parasitol Res (2012) 0.78

Elevated circulating CD14(low)CD16(+) monocyte subset in primary biliary cirrhosis correlates with liver injury and promotes Th1 polarization. Clin Exp Med (2015) 0.78

HIV-1 Resistant CDK2-Knockdown Macrophage-Like Cells Generated from 293T Cell-Derived Human Induced Pluripotent Stem Cells. Biology (Basel) (2012) 0.77

Identification and Characterization of CD300H, a New Member of the Human CD300 Immunoreceptor Family. J Biol Chem (2015) 0.77

Human monocyte subsets exhibit divergent angiotensin I-converting activity. Clin Exp Immunol (2015) 0.77

Effect of Tumor Necrosis Factor Inhibitor Therapy on Osteoclasts Precursors in Ankylosing Spondylitis. PLoS One (2015) 0.77

CD14(bright)CD16+ intermediate monocytes are induced by interleukin-10 and positively correlate with disease activity in rheumatoid arthritis. Arthritis Res Ther (2017) 0.76

The pattern of GPI-80 expression is a useful marker for unusual myeloid maturation in peripheral blood. Clin Exp Immunol (2016) 0.76

Enhanced apoptosis of monocytes from complication-free juvenile-onset diabetes mellitus type 1 may be ameliorated by TNF-α inhibitors. Mediators Inflamm (2014) 0.76

Induced pluripotent stem cells in hematology: current and future applications. Blood Cancer J (2014) 0.76

Sera from patients with active systemic lupus erythematosus patients enhance the toll-like receptor 4 response in monocyte subsets. J Inflamm (Lond) (2015) 0.76

Intermediate monocytes are increased in enthesitis-related arthritis, a category of juvenile idiopathic arthritis. Clin Exp Immunol (2016) 0.76

A cytofluorometric study of membrane rafts in human monocyte subsets in atherosclerosis. Acta Naturae (2014) 0.76

Expansion of CD14(+)CD16(+) monocytes is related to acute leukemia. Int J Clin Exp Med (2015) 0.76

Naturally Occurring Subclinical Endotoxemia in Humans Alters Adaptive and Innate Immune Functions through Reduced MAPK and Increased STAT1 Phosphorylation. J Immunol (2015) 0.76

Heterogeneity, functional specialization and differentiation of monocyte-derived dendritic cells. Immunol Cell Biol (2016) 0.76

Platelets induce a proinflammatory phenotype in monocytes via the CD147 pathway in rheumatoid arthritis. Arthritis Res Ther (2014) 0.75

A Csf1r-EGFP Transgene Provides a Novel Marker for Monocyte Subsets in Sheep. J Immunol (2016) 0.75

Targeting the Monocyte-Macrophage Lineage in Solid Organ Transplantation. Front Immunol (2017) 0.75

Counts of bovine monocyte subsets prior to calving are predictive for postpartum occurrence of mastitis and metritis. Vet Res (2017) 0.75

Application of Induced Pluripotent Stem Cell Technology to the Study of Hematological Diseases. Cells (2017) 0.75

The lack of BTK does not impair monocytes and polymorphonuclear cells functions in X-linked agammaglobulinemia under treatment with intravenous immunoglobulin replacement. PLoS One (2017) 0.75

Effect of Tumor Necrosis Factor Inhibitor Therapy on Osteoclasts Precursors in Rheumatoid Arthritis. Biomed Res Int (2017) 0.75

Monocyte Subsets Coregulate Inflammatory Responses by Integrated Signaling through TNF and IL-6 at the Endothelial Cell Interface. J Immunol (2017) 0.75

Dictionary-enhanced imaging cytometry. Sci Rep (2017) 0.75

Differential macrophage function in Brown Swiss and Holstein Friesian cattle. Vet Immunol Immunopathol (2016) 0.75

CD16+ Monocytes and Skewed Macrophage Polarization toward M2 Type Hallmark Heart Transplant Acute Cellular Rejection. Front Immunol (2017) 0.75

CD16(+) Monocyte Subset Was Enriched and Functionally Exacerbated in Driving T-Cell Activation and B-Cell Response in Systemic Lupus Erythematosus. Front Immunol (2016) 0.75

Effect of Periodic Granulocyte Colony-Stimulating Factor Administration on Endothelial Progenitor Cells and Different Monocyte Subsets in Pediatric Patients with Muscular Dystrophies. Stem Cells Int (2015) 0.75

DNA methylation profiling reveals differences in the 3 human monocyte subsets and identifies uremia to induce DNA methylation changes during differentiation. Epigenetics (2016) 0.75

Monocyte Subsets and Related Chemokines in Carotid Artery Stenosis and Ischemic Stroke. Int J Mol Sci (2016) 0.75

Expression profile of novel cell surface molecules on different subsets of human peripheral blood antigen-presenting cells. Clin Transl Immunology (2016) 0.75

Modulation of dendritic cell and monocyte subsets in tuberculosis-diabetes co-morbidity upon standard tuberculosis treatment. Tuberculosis (Edinb) (2016) 0.75

Empirical assessment of analysis workflows for differential expression analysis of human samples using RNA-Seq. BMC Bioinformatics (2017) 0.75

Ankylosing Spondylitis Patients Have Impaired Osteoclast Gene Expression in Circulating Osteoclast Precursors. Front Med (Lausanne) (2017) 0.75

Perturbations of Monocyte Subsets and Their Association with T Helper Cell Differentiation in Acute and Chronic HIV-1-Infected Patients. Front Immunol (2017) 0.75

TIE-2 expressing monocytes in human cancers. Oncoimmunology (2017) 0.75

Differential IL-1β secretion by monocyte subsets is regulated by Hsp27 through modulating mRNA stability. Sci Rep (2016) 0.75

Association of Canine Osteosarcoma and Monocyte Phenotype and Chemotactic Function. J Vet Intern Med (2016) 0.75

The Effect of Post-Resistance Exercise Amino Acids on Plasma MCP-1 and CCR2 Expression. Nutrients (2016) 0.75

Methotrexate and low-dose prednisolone downregulate osteoclast function by decreasing receptor activator of nuclear factor-κβ expression in monocytes from patients with early rheumatoid arthritis. RMD Open (2017) 0.75

Brucella Dysregulates Monocytes and Inhibits Macrophage Polarization through LC3-Dependent Autophagy. Front Immunol (2017) 0.75

Functional Analysis of Phagocyte Activity in Whole Blood from HIV/Tuberculosis-Infected Individuals Using a Novel Flow Cytometry-Based Assay. Front Immunol (2017) 0.75

CD16-positive circulating monocytes and fibrotic manifestations of systemic sclerosis. Clin Rheumatol (2017) 0.75

The MHC class II antigen presentation pathway in human monocytes differs by subset and is regulated by cytokines. PLoS One (2017) 0.75

Monocyte dysregulation and systemic inflammation during pediatric falciparum malaria. JCI Insight (2017) 0.75