I Julkunen

Author PubWeight™ 113.74‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Kinetics of human soluble and membrane-bound catechol O-methyltransferase: a revised mechanism and description of the thermolabile variant of the enzyme. Biochemistry 1995 4.10
2 Maturation, activation, and protection of dendritic cells induced by double-stranded RNA. J Exp Med 1999 3.64
3 Distinct patterns and kinetics of chemokine production regulate dendritic cell function. Eur J Immunol 1999 3.04
4 Infection of human macrophages and dendritic cells with Mycobacterium tuberculosis induces a differential cytokine gene expression that modulates T cell response. J Immunol 2001 2.83
5 High frequency of cross-reacting antibodies against 2009 pandemic influenza A(H1N1) virus among the elderly in Finland. Euro Surveill 2010 2.56
6 Identification of distinct signaling pathways leading to the phosphorylation of interferon regulatory factor 3. J Biol Chem 2001 2.47
7 Virus infection activates IL-1 beta and IL-18 production in human macrophages by a caspase-1-dependent pathway. J Immunol 1999 2.26
8 Interferons up-regulate STAT1, STAT2, and IRF family transcription factor gene expression in human peripheral blood mononuclear cells and macrophages. J Immunol 1997 2.01
9 Interferon-alpha activates multiple STAT proteins and upregulates proliferation-associated IL-2Ralpha, c-myc, and pim-1 genes in human T cells. Blood 1999 1.97
10 Lactobacilli and streptococci induce interleukin-12 (IL-12), IL-18, and gamma interferon production in human peripheral blood mononuclear cells. Infect Immun 1998 1.95
11 IFNs activate toll-like receptor gene expression in viral infections. Genes Immun 2001 1.90
12 Activation of IFN-alpha, IFN-gamma, MxA, and IFN regulatory factor 1 genes in influenza A virus-infected human peripheral blood mononuclear cells. J Immunol 1995 1.82
13 Influenza A virus-induced IFN-alpha/beta and IL-18 synergistically enhance IFN-gamma gene expression in human T cells. J Immunol 1998 1.71
14 Regulation of IFN-alpha/beta, MxA, 2',5'-oligoadenylate synthetase, and HLA gene expression in influenza A-infected human lung epithelial cells. J Immunol 1997 1.69
15 Arginine/lysine-rich structural element is involved in interferon-induced nuclear import of STATs. J Biol Chem 2001 1.68
16 Human B-cell epitopes of Puumala virus nucleocapsid protein, the major antigen in early serological response. J Med Virol 1995 1.61
17 Impaired antiviral response in human hepatoma cells. Virology 1999 1.52
18 IFN-alpha and IL-18 synergistically enhance IFN-gamma production in human NK cells: differential regulation of Stat4 activation and IFN-gamma gene expression by IFN-alpha and IL-12. Eur J Immunol 2001 1.51
19 Enzyme immunoassay, complement fixation and hemagglutination inhibition tests in the diagnosis of influenza A and B virus infections. Purified hemagglutinin in subtype-specific diagnosis. J Virol Methods 1985 1.46
20 IFN-alpha and IL-12 induce IL-18 receptor gene expression in human NK and T cells. J Immunol 2000 1.43
21 Influenza A and sendai viruses induce differential chemokine gene expression and transcription factor activation in human macrophages. Virology 2000 1.41
22 Proteome analysis reveals ubiquitin-conjugating enzymes to be a new family of interferon-alpha-regulated genes. Eur J Biochem 2000 1.38
23 Lactobacilli and Streptococci activate NF-kappa B and STAT signaling pathways in human macrophages. J Immunol 2000 1.37
24 Control of IFN-inducible MxA gene expression in human cells. J Immunol 1993 1.35
25 Antigenic properties and diagnostic potential of puumala virus nucleocapsid protein expressed in insect cells. J Clin Microbiol 1996 1.35
26 Induction of IRF-3 and IRF-7 phosphorylation following activation of the RIG-I pathway. Cell Mol Biol (Noisy-le-grand) 2006 1.33
27 Human MxB protein, an interferon-alpha-inducible GTPase, contains a nuclear targeting signal and is localized in the heterochromatin region beneath the nuclear envelope. J Biol Chem 1996 1.32
28 Requirement of mature dendritic cells for efficient activation of influenza A-specific memory CD8+ T cells. J Immunol 2000 1.31
29 Interaction of viral envelope glycoproteins with fibronectin. Infect Immun 1983 1.21
30 Efficacy of PCR and other diagnostic methods for the detection of respiratory adenoviral infections. J Med Virol 1999 1.18
31 Interferon-induced Mx proteins form oligomers and contain a putative leucine zipper. J Biol Chem 1992 1.17
32 Inhibition of puumala and tula hantaviruses in Vero cells by MxA protein. Virology 1996 1.16
33 Virus infection induces proteolytic processing of IL-18 in human macrophages via caspase-1 and caspase-3 activation. Eur J Immunol 2001 1.15
34 Retinoic acid activates interferon regulatory factor-1 gene expression in myeloid cells. Blood 1996 1.13
35 Measles virus activates NF-kappa B and STAT transcription factors and production of IFN-alpha/beta and IL-6 in the human lung epithelial cell line A549. Virology 2001 1.11
36 Interferon-induced gene expression and signaling in human hepatoma cell lines. J Hepatol 2000 1.08
37 Rapid diagnosis of respiratory adenovirus infections in young adult men. J Clin Microbiol 1986 1.08
38 Lysosomal aspartylglucosaminidase is processed to the active subunit complex in the endoplasmic reticulum. EMBO J 1993 1.06
39 The proximal interferon-stimulated response elements are essential for interferon responsiveness: a promoter analysis of the antiviral MxA gene. J Interferon Cytokine Res 1998 1.03
40 Effect of interferon-alpha and cell differentiation on Puumala virus infection in human monocyte/macrophages. Virology 1995 1.03
41 Serological diagnosis of influenza A and B infections by enzyme immunoassay. Comparison with the complement fixation test. J Virol Methods 1984 1.02
42 Serological diagnosis of parainfluenza virus infections by enzyme immunoassay with special emphasis on purity of viral antigens. J Med Virol 1984 1.00
43 Persistence of anti-mumps virus antibodies after a two-dose MMR vaccination. A nine-year follow-up. Vaccine 1995 0.98
44 Parental influenza virion nucleocapsids are efficiently transported into the nuclei of murine cells expressing the nuclear interferon-induced Mx protein. J Virol 1990 0.96
45 Chondroitin sulfate at the plasma membranes of cultured fibroblasts. J Cell Biol 1983 0.96
46 Role of N-glycosylation in the synthesis, dimerization and secretion of human interferon-gamma. Biochem J 1994 0.96
47 Inhibition of human natural killer cell activity by cereulide, an emetic toxin from Bacillus cereus. Clin Exp Immunol 2002 0.95
48 Effect of carbohydrates on the pharmacokinetics of human interferon-gamma. J Interferon Res 1993 0.94
49 Surveillance of influenza in Finland during the 2009 pandemic, 10 May 2009 to 8 March 2010. Euro Surveill 2011 0.94
50 Viral antibodies and interferon in acute psychiatric disorders. J Clin Psychiatry 1987 0.94
51 Inhibition of human NK cell function by valinomycin, a toxin from Streptomyces griseus in indoor air. Infect Immun 2000 0.93
52 Enzymatic characterization of interferon-induced antiviral GTPases murine Mx1 and human MxA proteins. J Biol Chem 1994 0.92
53 Secretion and biological activities of heparin-binding growth-associated molecule. Neurite outgrowth-promoting and mitogenic actions of the recombinant and tissue-derived protein. J Biol Chem 1992 0.91
54 Retinoic acid induces signal transducer and activator of transcription (STAT) 1, STAT2, and p48 expression in myeloid leukemia cells and enhances their responsiveness to interferons. Cell Growth Differ 1997 0.91
55 Distribution of catechol-O-methyltransferase enzyme in rat tissues. J Histochem Cytochem 1994 0.90
56 Nuclear cotransport mechanism of cytoplasmic human MxB protein. J Biol Chem 1997 0.90
57 Biosynthesis and N-glycosylation of human interferon-gamma. Asn25 and Asn97 differ markedly in how efficiently they are glycosylated and in their oligosaccharide composition. Eur J Biochem 1996 0.89
58 Immunoglobulin G subclass antibody responses in influenza A and parainfluenza type 1 virus infections. Clin Exp Immunol 1985 0.89
59 Phospholipid transfer is a prerequisite for PLTP-mediated HDL conversion. Biochemistry 2000 0.88
60 Lactobacillus rhamnosus GG and Streptococcus thermophilus induce suppressor of cytokine signalling 3 (SOCS3) gene expression directly and indirectly via interleukin-10 in human primary macrophages. Clin Exp Immunol 2011 0.88
61 Etiology of central nervous system infections in the Philippines and the role of serum C-reactive protein in excluding acute bacterial meningitis. Int J Infect Dis 1999 0.87
62 N-glycosylation of human interferon-gamma: glycans at Asn-25 are critical for protease resistance. Biochem J 1995 0.87
63 Reduced cross-protection against influenza A(H3N2) subgroup 3C.2a and 3C.3a viruses among Finnish healthcare workers vaccinated with 2013/14 seasonal influenza vaccine. Euro Surveill 2015 0.87
64 Mutational analysis of murine Mx1 protein: GTP binding core domain is essential for anti-influenza A activity. Virology 1994 0.87
65 Cells of the neuronal lineage play a major role in the generation of amyloid precursor fragments in gelsolin-related amyloidosis. J Biol Chem 1998 0.87
66 Detection of rotavirus in faecal specimens by enzyme immunoassay, latex agglutination and electron microscopy. Scand J Infect Dis 1985 0.87
67 Measles virus enhances the expression of cellular immediate-early genes and DNA-binding of transcription factor AP-1 in lung epithelial A549 cells. Arch Virol 2002 0.87
68 Expression of MxA protein in blood lymphocytes discriminates between viral and bacterial infections in febrile children. Pediatr Res 1997 0.86
69 Primary folding of aspartylglucosaminidase. Significance of disulfide bridges and evidence of early multimerization. J Biol Chem 1996 0.85
70 Localization of viral-envelope-glycoprotein-binding sites in fibronectin. Biochem J 1984 0.84
71 Regulation of IRF and STAT gene expression by retinoic acid. Leuk Lymphoma 1998 0.84
72 Expression of recombinant soluble and membrane-bound catechol O-methyltransferase in eukaryotic cells and identification of the respective enzymes in rat brain. Eur J Biochem 1992 0.84
73 Proportions of immunoglobulin isotypes in paralytic poliomyelitis and after vaccination. J Clin Immunol 1987 0.84
74 Regulation of HLA class I and II expression by interferons and influenza A virus in human peripheral blood mononuclear cells. Immunology 1997 0.84
75 Immune complex assays and stored normal human sera. J Immunol Methods 1983 0.83
76 Neutralizing antibodies reduce MxA protein induction in interferon-beta-1a-treated MS patients. Neurology 2002 0.81
77 Immunoglobulin class-specific serological responses to adenovirus in respiratory infections of young adult men. J Clin Microbiol 1986 0.81
78 Lack of induction by rhinoviruses of systemic type I interferon production or enhanced MxA protein expression during the common cold. Eur J Clin Microbiol Infect Dis 1999 0.81
79 Differential inactivation of interferons by a protease from human granulocytes. J Interferon Res 1992 0.81
80 Immune complexes in serum and cerebrospinal fluid of multiple sclerosis patients and patients with other neurological diseases. Acta Neurol Scand 1982 0.80
81 Mass spectrometric characterization of glycosylated interferon-gamma variants separated by gel electrophoresis. Electrophoresis 1996 0.80
82 Anticancer compound ABT-263 accelerates apoptosis in virus-infected cells and imbalances cytokine production and lowers survival rates of infected mice. Cell Death Dis 2013 0.79
83 Elevated serum immune complex levels in Pogosta disease, an acute alphavirus infection with rash and arthritis. J Clin Lab Immunol 1986 0.79
84 Fibronectin and viral pathogenesis. Rev Infect Dis 1988 0.78
85 Circulating immune complexes in Yersinia infection. J Rheumatol 1984 0.78
86 Kinetics of cytokine and NFAT gene expression in human interleukin-2-dependent T lymphoblasts stimulated via T-cell receptor. Immunology 1998 0.78
87 Gm allotypes influence the production of IgG3 but the effect is age-dependent. Hum Immunol 1991 0.78
88 Sensitive interferon assay based on immunoenzymatic quantification of viral antigen synthesis. J Virol Methods 1982 0.78
89 Chronic mumps virus encephalitis. Mumps antibody levels in cerebrospinal fluid. J Neuroimmunol 1985 0.77
90 Sudden deafness: lack of evidence for systemic viral infection. Otolaryngol Head Neck Surg 1998 0.77
91 Dynamin inhibition interferes with inflammasome activation and cytokine gene expression in Streptococcus pyogenes-infected human macrophages. Clin Exp Immunol 2014 0.77
92 Chronic encephalomyelitis with specific increase in intrathecal mumps antibodies. Lancet 1982 0.77
93 Elevated mumps antibody titers in the cerebrospinal fluid suggesting chronic mumps virus infection in the central nervous system. Pediatr Infect Dis 1985 0.76
94 C3c-binding in inflammatory rheumatic diseases. Clin Exp Rheumatol 1985 0.76
95 Establishment and characterization of a rat glomerular endothelial cell line. Lab Invest 1993 0.75
96 Antibody responses to mumps virus proteins in natural mumps infection and after vaccination with live and inactivated mumps virus vaccines. J Med Virol 1984 0.75
97 Etiological, social and therapeutical aspects of osteoarthrosis and soft-tissue rheumatism in a Finnish health centre material. Scand J Rheumatol 1981 0.75
98 [Nuclear pathway of interferons]. Duodecim 1993 0.75
99 Proportions of Ig classes and subclasses in mumps antibodies. Scand J Immunol 1985 0.75
100 Mental retardation associated with elevated cerebrospinal fluid antibody levels to herpes simplex, adeno and mumps viruses. Neuropediatrics 1987 0.75
101 Does matrix-assisted laser desorption/ionization mass spectrometry allow analysis of carbohydrate heterogeneity in glycoproteins? A study of natural human interferon-gamma. J Mass Spectrom 1996 0.75
102 Serum immune complexes and rheumatoid factors in superficial bladder tumours. J Clin Lab Immunol 1987 0.75
103 Preparation of nasopharyngeal secretions for immunofluorescence by one-step centrifugation through Percoll. J Virol Methods 1987 0.75
104 C3b binding and IgG binding onto platelets in hepatitis B virus infection. Clin Immunol Immunopathol 1980 0.75
105 [Chronic encephalitis caused by mumps virus]. Duodecim 1986 0.75
106 Impaired interferon production by leukocytes from patients with Bell palsy and lack of findings suggestive for a systemic viral involvement. Am J Otol 1997 0.75