PubRank

R M Krug

Author PubWeight™ 170.72‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A unique cap(m7GpppXm)-dependent influenza virion endonuclease cleaves capped RNAs to generate the primers that initiate viral RNA transcription. Cell 1981 8.09
2 Influenza virus NS1 protein interacts with the cellular 30 kDa subunit of CPSF and inhibits 3'end formation of cellular pre-mRNAs. Mol Cell 1998 5.60
3 Role of two of the influenza virus core P proteins in recognizing cap 1 structures (m7GpppNm) on RNAs and in initiating viral RNA transcription. Proc Natl Acad Sci U S A 1981 5.10
4 Influenza B virus NS1 protein inhibits conjugation of the interferon (IFN)-induced ubiquitin-like ISG15 protein. EMBO J 2001 4.61
5 Binding of the influenza virus NS1 protein to double-stranded RNA inhibits the activation of the protein kinase that phosphorylates the elF-2 translation initiation factor. Virology 1995 4.43
6 Globin mRNAs are primers for the transcription of influenza viral RNA in vitro. Proc Natl Acad Sci U S A 1978 4.17
7 Molecular model of a eucaryotic transcription complex: functions and movements of influenza P proteins during capped RNA-primed transcription. Cell 1983 3.93
8 Influenza virus RNA replication in vitro: synthesis of viral template RNAs and virion RNAs in the absence of an added primer. J Virol 1988 3.49
9 The influenza virus NS1 protein is a poly(A)-binding protein that inhibits nuclear export of mRNAs containing poly(A). J Virol 1994 3.48
10 Influenza virion transcriptase: synthesis in vitro of large, polyadenylic acid-containing complementary RNA. J Virol 1977 3.38
11 Influenza A virus NS1 protein targets poly(A)-binding protein II of the cellular 3'-end processing machinery. EMBO J 1999 3.35
12 Are the 5' ends of influenza viral mRNAs synthesized in vivo donated by host mRNAs? Cell 1979 3.35
13 RNA binding by the novel helical domain of the influenza virus NS1 protein requires its dimer structure and a small number of specific basic amino acids. RNA 1999 3.28
14 Transfer of 5'-terminal cap of globin mRNA to influenza viral complementary RNA during transcription in vitro. Proc Natl Acad Sci U S A 1979 3.10
15 Transcription antitermination during influenza viral template RNA synthesis requires the nucleocapsid protein and the absence of a 5' capped end. Proc Natl Acad Sci U S A 1986 3.09
16 Temperature-sensitive mutants of influenza WSN virus defective in virus-specific RNA synthesis. J Virol 1975 2.72
17 Priming of influenza viral RNA transcription by capped heterologous RNAs. Curr Top Microbiol Immunol 1981 2.68
18 The influenza virus NS1 protein: a novel inhibitor of pre-mRNA splicing. Genes Dev 1994 2.64
19 Both the 7-methyl and the 2'-O-methyl groups in the cap of mRNA strongly influence its ability to act as primer for influenza virus RNA transcription. Proc Natl Acad Sci U S A 1980 2.56
20 Two functional domains of the influenza virus NS1 protein are required for regulation of nuclear export of mRNA. J Virol 1994 2.54
21 Influenza virus temperature-sensitive cap (m7GpppNm)-dependent endonuclease. J Virol 1983 2.53
22 The active sites of the influenza cap-dependent endonuclease are on different polymerase subunits. EMBO J 2001 2.52
23 Crystal structure of the unique RNA-binding domain of the influenza virus NS1 protein. Nat Struct Biol 1997 2.41
24 Cytoplasmic and nuclear virus-specific proteins in influenza virus-infected MDCK cells. Virology 1973 2.40
25 Inhibition of influenza viral mRNA synthesis in cells expressing the interferon-induced Mx gene product. J Virol 1985 2.38
26 Influenza viral mRNA contains internal N6-methyladenosine and 5'-terminal 7-methylguanosine in cap structures. J Virol 1976 2.22
27 Influenza virus gene expression: control mechanisms at early and late times of infection and nuclear-cytoplasmic transport of virus-specific RNAs. J Virol 1987 2.21
28 The three influenza virus polymerase (P) proteins not associated with viral nucleocapsids in the infected cell are in the form of a complex. J Virol 1987 2.20
29 Influenza viral RNPs newly synthesized during the latent period of viral growth in MDCK cells. Virology 1971 2.19
30 Purification of influenza viral complementary RNA: its genetic content and activity in wheat germ cell-free extracts. J Virol 1975 2.17
31 A novel RNA-binding motif in influenza A virus non-structural protein 1. Nat Struct Biol 1997 2.16
32 The influenza virus NS1 protein binds to a specific region in human U6 snRNA and inhibits U6-U2 and U6-U4 snRNA interactions during splicing. RNA 1995 2.12
33 RNA-dependent activation of primer RNA production by influenza virus polymerase: different regions of the same protein subunit constitute the two required RNA-binding sites. EMBO J 1998 2.01
34 Influenza viral messenger RNA. Virology 1974 1.99
35 Segments of influenza virus complementary RNA synthesized in vitro. J Virol 1978 1.97
36 Metabolism and expression of RNA polymerase II transcripts in influenza virus-infected cells. Mol Cell Biol 1984 1.97
37 Cap and internal nucleotides of reovirus mRNA primers are incorporated into influenza viral complementary RNA during transcription in vitro. J Virol 1979 1.95
38 The 3'-end-processing factor CPSF is required for the splicing of single-intron pre-mRNAs in vivo. RNA 2001 1.94
39 Regulation of a nuclear export signal by an adjacent inhibitory sequence: the effector domain of the influenza virus NS1 protein. Proc Natl Acad Sci U S A 1998 1.94
40 Cytoplasmic and nucleoplasmic viral RNPs in influenza virus-infected MDCK cells. Virology 1972 1.92
41 Influenza virus regulates protein synthesis during infection by repressing autophosphorylation and activity of the cellular 68,000-Mr protein kinase. J Virol 1988 1.77
42 The influenza virus NS1 protein forms multimers in vitro and in vivo. Virology 1995 1.74
43 Priming and inhibitory activities of RNAs for the influenza viral transcriptase do not require base pairing with the virion template RNA. Proc Natl Acad Sci U S A 1980 1.72
44 Translational control by influenza virus: suppression of the kinase that phosphorylates the alpha subunit of initiation factor eIF-2 and selective translation of influenza viral mRNAs. Mol Cell Biol 1986 1.61
45 The RNA-binding and effector domains of the viral NS1 protein are conserved to different extents among influenza A and B viruses. Virology 1996 1.60
46 Cellular mRNA translation is blocked at both initiation and elongation after infection by influenza virus or adenovirus. J Virol 1986 1.59
47 An amino-terminal polypeptide fragment of the influenza virus NS1 protein possesses specific RNA-binding activity and largely helical backbone structure. RNA 1995 1.59
48 Nucleocytoplasmic transport: the influenza virus NS1 protein regulates the transport of spliced NS2 mRNA and its precursor NS1 mRNA. Genes Dev 1992 1.59
49 Nuclear-cytoplasmic transport and VAI RNA-independent translation of influenza viral messenger RNAs in late adenovirus-infected cells. Cell 1984 1.57
50 Identification of the RNA region transferred from a representative primer, beta-globin mRNA, to influenza mRNA during in vitro transcription. Nucleic Acids Res 1980 1.55
51 Nuclear accumulation of influenza viral RNA transcripts and the effects of cycloheximide, actinomycin D, and alpha-amanitin. J Virol 1979 1.54
52 The segments of influenza viral mRNA. J Virol 1977 1.51
53 Synthesis of the templates for influenza virion RNA replication in vitro. Proc Natl Acad Sci U S A 1984 1.45
54 Selected host cell capped RNA fragments prime influenza viral RNA transcription in vivo. Nucleic Acids Res 1981 1.43
55 Two of the three influenza viral polymerase proteins expressed by using baculovirus vectors form a complex in insect cells. J Virol 1987 1.41
56 Studies on the intranuclear localization of influenza virus-specific proteins. Virology 1975 1.38
57 Use of specific radioactive probes to study transcription and replication of the influenza virus genome. J Virol 1977 1.36
58 Selective nuclear export of viral mRNAs in influenza-virus-infected cells. Trends Microbiol 2000 1.33
59 Studies on the helical nucleocapsid of influenza virus. Virology 1982 1.27
60 In vitro splicing of influenza viral NS1 mRNA and NS1-beta-globin chimeras: possible mechanisms for the control of viral mRNA splicing. Proc Natl Acad Sci U S A 1986 1.25
61 The choice of alternative 5' splice sites in influenza virus M1 mRNA is regulated by the viral polymerase complex. Proc Natl Acad Sci U S A 1995 1.23
62 Identification of cis-acting intron and exon regions in influenza virus NS1 mRNA that inhibit splicing and cause the formation of aberrantly sedimenting presplicing complexes. Mol Cell Biol 1992 1.23
63 Surprising function of the three influenza viral polymerase proteins: selective protection of viral mRNAs against the cap-snatching reaction catalyzed by the same polymerase proteins. Virology 1996 1.20
64 New ways of initiating translation in eukaryotes. Mol Cell Biol 2001 1.20
65 Interferon-induced Mx proteins form oligomers and contain a putative leucine zipper. J Biol Chem 1992 1.17
66 U6atac snRNA, the highly divergent counterpart of U6 snRNA, is the specific target that mediates inhibition of AT-AC splicing by the influenza virus NS1 protein. RNA 1998 1.16
67 Efficient transcription, not translation, is dependent on adenovirus tripartite leader sequences at late times of infection. J Virol 1988 1.15
68 Expression of a functional influenza viral cap-recognizing protein by using a bovine papilloma virus vector. Proc Natl Acad Sci U S A 1985 1.14
69 Absence of detectable capping and methylating enzymes in influenza virions. J Virol 1978 1.14
70 Novel exploitation of a nuclear function by influenza virus: the cellular SF2/ASF splicing factor controls the amount of the essential viral M2 ion channel protein in infected cells. EMBO J 1996 1.13
71 The role of RNA priming in viral and trypanosomal mRNA synthesis. Cell 1985 1.10
72 Regulation of the extent of splicing of influenza virus NS1 mRNA: role of the rates of splicing and of the nucleocytoplasmic transport of NS1 mRNA. Mol Cell Biol 1991 1.08
73 Translational control in influenza virus-infected cells. Enzyme 1990 1.07
74 Absence of adenine-rich ribonucleic acid from purified infectious reovirus 3. J Virol 1969 1.06
75 A block in mammalian splicing occurring after formation of large complexes containing U1, U2, U4, U5, and U6 small nuclear ribonucleoproteins. Mol Cell Biol 1989 0.99
76 Parental influenza virion nucleocapsids are efficiently transported into the nuclei of murine cells expressing the nuclear interferon-induced Mx protein. J Virol 1990 0.96
77 Enzymic synthesis of RNA with reovirus RNA as template. II. Nearest neighbor analysis of the products of the reaction catalyzed by the Escherichia coli RNA polymerase. J Mol Biol 1965 0.91
78 Chimeras containing influenza NS1 and HIV-1 Rev protein sequences: mechanism of their inhibition of nuclear export of Rev protein-RNA complexes. Virology 1998 0.82
79 RNA primers and the role of host nuclear RNA polymerase II in influenza viral RNA transcription. Philos Trans R Soc Lond B Biol Sci 1980 0.81
80 Efficient translation of mRNAs in influenza A virus-infected cells is independent of the viral 5' untranslated region. Virology 2001 0.80
81 New approach for inhibiting Rev function and HIV-1 production using the influenza virus NS1 protein. Proc Natl Acad Sci U S A 1996 0.77
82 Chemical synthesis of 5'-pyrophosphate and triphosphate derivatives of 3'-5' ApA, ApG, GpA and GpG. CD study of the effect of 5'-phosphate groups on the conformation of 3'-5' GpG. Nucleic Acids Res 1978 0.75