Published in Appl Magn Reson on February 03, 2012
Structural Insights into the Dynamic Process of β2-Adrenergic Receptor Signaling. Cell (2015) 1.68
Technological advances in site-directed spin labeling of proteins. Curr Opin Struct Biol (2013) 1.36
Conformational state of the MscS mechanosensitive channel in solution revealed by pulsed electron-electron double resonance (PELDOR) spectroscopy. Proc Natl Acad Sci U S A (2012) 1.03
The histone chaperones Vps75 and Nap1 form ring-like, tetrameric structures in solution. Nucleic Acids Res (2014) 1.03
Probing the structure of the mechanosensitive channel of small conductance in lipid bilayers with pulsed electron-electron double resonance. Biophys J (2014) 0.92
RosettaEPR: rotamer library for spin label structure and dynamics. PLoS One (2013) 0.87
Perturbations of the straight transmembrane α-helical structure of the amyloid precursor protein affect its processing by γ-secretase. J Biol Chem (2014) 0.85
Identifying and quantitating conformational exchange in membrane proteins using site-directed spin labeling. Acc Chem Res (2014) 0.84
The architecture of EssB, an integral membrane component of the type VII secretion system. Structure (2013) 0.83
PELDOR in rotationally symmetric homo-oligomers. Mol Phys (2013) 0.83
The double-histidine Cu²⁺-binding motif: a highly rigid, site-specific spin probe for electron spin resonance distance measurements. Angew Chem Int Ed Engl (2015) 0.81
Closure of the cytoplasmic gate formed by TM5 and TM11 during transport in the oxalate/formate exchanger from Oxalobacter formigenes. Biochemistry (2014) 0.80
Analysis of influenza A virus NS1 dimer interfaces in solution by pulse EPR distance measurements. J Phys Chem B (2014) 0.80
Taking a molecular motor for a spin: helicase mechanism studied by spin labeling and PELDOR. Nucleic Acids Res (2015) 0.80
mtsslSuite: In silico spin labelling, trilateration and distance-constrained rigid body docking in PyMOL. Mol Phys (2013) 0.80
Simulating the distance distribution between spin-labels attached to proteins. J Phys Chem B (2015) 0.80
High-resolution crystal structure of spin labelled (T21R1) azurin from Pseudomonas aeruginosa: a challenging structural benchmark for in silico spin labelling algorithms. BMC Struct Biol (2014) 0.78
Connecting lipoxygenase function to structure by electron paramagnetic resonance. Acc Chem Res (2014) 0.78
DEER Sensitivity between Iron Centers and Nitroxides in Heme-Containing Proteins Improves Dramatically Using Broadband, High-Field EPR. J Phys Chem Lett (2016) 0.77
Genetic Incorporation of the Unnatural Amino Acid p-Acetyl Phenylalanine into Proteins for Site-Directed Spin Labeling. Methods Enzymol (2015) 0.77
Interaction between Prion Protein's Copper-Bound Octarepeat Domain and a Charged C-Terminal Pocket Suggests a Mechanism for N-Terminal Regulation. Structure (2016) 0.77
The histone chaperone Vps75 forms multiple oligomeric assemblies capable of mediating exchange between histone H3-H4 tetramers and Asf1-H3-H4 complexes. Nucleic Acids Res (2016) 0.77
An Integrated Spin-Labeling/Computational-Modeling Approach for Mapping Global Structures of Nucleic Acids. Methods Enzymol (2015) 0.77
Modeling of the N-terminal Section and the Lumenal Loop of Trimeric Light Harvesting Complex II (LHCII) by Using EPR. J Biol Chem (2015) 0.76
Membrane Docking of the Synaptotagmin 7 C2A Domain: Electron Paramagnetic Resonance Measurements Show Contributions from Two Membrane Binding Loops. Biochemistry (2015) 0.76
Characterization of the Domain Orientations of E. coli 5'-Nucleotidase by Fitting an Ensemble of Conformers to DEER Distance Distributions. Structure (2015) 0.75
Rotameric preferences of a protein spin label at edge-strand β-sheet sites. Protein Sci (2016) 0.75
Studies on the X-Ray and Solution Structure of FeoB from Escherichia coli BL21. Biophys J (2016) 0.75
(19) F Paramagnetic Relaxation Enhancement: A Valuable Tool for Distance Measurements in Proteins. Angew Chem Int Ed Engl (2015) 0.75
Modelling multi-protein complexes using PELDOR distance measurements for rigid body minimisation experiments using XPLOR-NIH. Methods (2014) 0.75
PELDOR Spectroscopy Reveals Two Defined States of a Sialic Acid TRAP Transporter SBP in Solution. Biophys J (2017) 0.75
Relative Orientation of POTRA Domains from Cyanobacterial Omp85 Studied by Pulsed EPR Spectroscopy. Biophys J (2016) 0.75
Structural basis for antibacterial peptide self-immunity by the bacterial ABC transporter McjD. EMBO J (2017) 0.75
Monitoring Complex Formation by Relaxation-Induced Pulse Electron Paramagnetic Resonance Distance Measurements. Chemphyschem (2017) 0.75
Chemistry of ion coordination and hydration revealed by a K+ channel-Fab complex at 2.0 A resolution. Nature (2001) 13.76
Transmembrane protein structure: spin labeling of bacteriorhodopsin mutants. Science (1990) 4.07
Crystal structures of spin labeled T4 lysozyme mutants: implications for the interpretation of EPR spectra in terms of structure. Biochemistry (2000) 3.46
Structure of bacteriophage T4 lysozyme refined at 1.7 A resolution. J Mol Biol (1987) 3.02
Rotamer libraries of spin labelled cysteines for protein studies. Phys Chem Chem Phys (2010) 2.78
Wza the translocon for E. coli capsular polysaccharides defines a new class of membrane protein. Nature (2006) 2.77
Protein structure determination using long-distance constraints from double-quantum coherence ESR: study of T4 lysozyme. J Am Chem Soc (2002) 2.48
Structural determinants of nitroxide motion in spin-labeled proteins: tertiary contact and solvent-inaccessible sites in helix G of T4 lysozyme. Protein Sci (2007) 2.01
Structural determinants of nitroxide motion in spin-labeled proteins: solvent-exposed sites in helix B of T4 lysozyme. Protein Sci (2007) 1.87
De novo high-resolution protein structure determination from sparse spin-labeling EPR data. Structure (2008) 1.84
A novel reversible thiol-specific spin label: papain active site labeling and inhibition. Anal Biochem (1982) 1.79
Conformational motion of the ABC transporter MsbA induced by ATP hydrolysis. PLoS Biol (2007) 1.76
Structural origin of weakly ordered nitroxide motion in spin-labeled proteins. Protein Sci (2009) 1.68
Calculation of electron paramagnetic resonance spectra from Brownian dynamics trajectories: application to nitroxide side chains in proteins. Biophys J (1996) 1.55
RosettaEPR: an integrated tool for protein structure determination from sparse EPR data. J Struct Biol (2010) 1.50
Calculating slow-motional electron paramagnetic resonance spectra from molecular dynamics using a diffusion operator approach. J Phys Chem A (2006) 1.37
A structure-based simulation approach for electron paramagnetic resonance spectra using molecular and stochastic dynamics simulations. Biophys J (2006) 1.36
Pulsed electron-electron double resonance: beyond nanometre distance measurements on biomacromolecules. Biochem J (2011) 1.29
Dipolar coupling between nitroxide spin labels: the development and application of a tether-in-a-cone model. Biophys J (2005) 1.26
Pulsed electron-electron double-resonance determination of spin-label distances and orientations on the tetrameric potassium ion channel KcsA. J Am Chem Soc (2009) 1.26
Multifrequency electron spin resonance spectra of a spin-labeled protein calculated from molecular dynamics simulations. J Am Chem Soc (2009) 1.25
Transmembrane signaling in the maltose ABC transporter MalFGK2-E: periplasmic MalF-P2 loop communicates substrate availability to the ATP-bound MalK dimer. J Biol Chem (2009) 1.22
Probing the (H3-H4)2 histone tetramer structure using pulsed EPR spectroscopy combined with site-directed spin labelling. Nucleic Acids Res (2009) 1.20
Solution structure of the cytoplasmic domain of erythrocyte membrane band 3 determined by site-directed spin labeling. Biochemistry (2005) 1.18
PELDOR spectroscopy distance fingerprinting of the octameric outer-membrane protein Wza from Escherichia coli. Angew Chem Int Ed Engl (2009) 1.10
Simulation of nitroxide electron paramagnetic resonance spectra from brownian trajectories and molecular dynamics simulations. Biophys J (2008) 1.07
Structure of Spa15, a type III secretion chaperone from Shigella flexneri with broad specificity. EMBO Rep (2004) 1.03
Studying biomolecular complexes with pulsed electron-electron double resonance spectroscopy. Biochem Soc Trans (2011) 1.02
High-resolution structure of the native histone octamer. Acta Crystallogr Sect F Struct Biol Cryst Commun (2005) 1.02
Algorithm for selection of optimized EPR distance restraints for de novo protein structure determination. J Struct Biol (2010) 1.02
Determination of structural models of the complex between the cytoplasmic domain of erythrocyte band 3 and ankyrin-R repeats 13-24. J Biol Chem (2011) 0.96
Shigella flexneri Spa15 crystal structure verified in solution by double electron electron resonance. J Mol Biol (2010) 0.91
Conformational flexibility of DNA. J Am Chem Soc (2011) 0.89
A general approach for prediction of motional EPR spectra from Molecular Dynamics (MD) simulations: application to spin labelled protein. Phys Chem Chem Phys (2011) 0.86
2012 update of the Canadian Cardiovascular Society guidelines for the diagnosis and treatment of dyslipidemia for the prevention of cardiovascular disease in the adult. Can J Cardiol (2013) 5.97
Structure and mechanism of the CMR complex for CRISPR-mediated antiviral immunity. Mol Cell (2012) 3.41
An efficient one-step site-directed deletion, insertion, single and multiple-site plasmid mutagenesis protocol. BMC Biotechnol (2008) 3.27
Structure of a RING E3 ligase and ubiquitin-loaded E2 primed for catalysis. Nature (2012) 2.86
Structural and functional characterization of an archaeal clustered regularly interspaced short palindromic repeat (CRISPR)-associated complex for antiviral defense (CASCADE). J Biol Chem (2011) 2.86
Wza the translocon for E. coli capsular polysaccharides defines a new class of membrane protein. Nature (2006) 2.77
The structure of an open form of an E. coli mechanosensitive channel at 3.45 A resolution. Science (2008) 2.21
Structure of the DNA repair helicase XPD. Cell (2008) 2.16
Tryptophan 7-halogenase (PrnA) structure suggests a mechanism for regioselective chlorination. Science (2005) 2.10
TarO: a target optimisation system for structural biology. Nucleic Acids Res (2008) 1.89
SUMO protease SENP1 induces isomerization of the scissile peptide bond. Nat Struct Mol Biol (2006) 1.89
Pivotal roles of the outer membrane polysaccharide export and polysaccharide copolymerase protein families in export of extracellular polysaccharides in gram-negative bacteria. Microbiol Mol Biol Rev (2009) 1.82
Crystal structure and mechanism of a bacterial fluorinating enzyme. Nature (2004) 1.70
The Scottish Structural Proteomics Facility: targets, methods and outputs. J Struct Funct Genomics (2010) 1.66
A simple and efficient expression and purification system using two newly constructed vectors. Protein Expr Purif (2008) 1.64
Effector role of neonatal hepatic CD8+ lymphocytes in epithelial injury and autoimmunity in experimental biliary atresia. Gastroenterology (2007) 1.62
Mechanism of the Class I KDPG aldolase. Bioorg Med Chem (2006) 1.62
Mechanism of ubiquitylation by dimeric RING ligase RNF4. Nat Struct Mol Biol (2011) 1.59
Insights into ssDNA recognition by the OB fold from a structural and thermodynamic study of Sulfolobus SSB protein. EMBO J (2003) 1.58
The mechanism of patellamide macrocyclization revealed by the characterization of the PatG macrocyclase domain. Nat Struct Mol Biol (2012) 1.53
Wzi is an outer membrane lectin that underpins group 1 capsule assembly in Escherichia coli. Structure (2013) 1.51
The structure of SENP1-SUMO-2 complex suggests a structural basis for discrimination between SUMO paralogues during processing. Biochem J (2006) 1.49
Structural basis of NEDD8 ubiquitin discrimination by the deNEDDylating enzyme NEDP1. EMBO J (2005) 1.48
CRISPR interference: a structural perspective. Biochem J (2013) 1.48
Counting the monomers in nanometer-sized oligomers by pulsed electron-electron double resonance. J Am Chem Soc (2007) 1.43
Extensive DNA mimicry by the ArdA anti-restriction protein and its role in the spread of antibiotic resistance. Nucleic Acids Res (2009) 1.38
The structure of serine palmitoyltransferase; gateway to sphingolipid biosynthesis. J Mol Biol (2007) 1.38
PELDOR at S- and X-band frequencies and the separation of exchange coupling from dipolar coupling. J Magn Reson (2002) 1.37
Translocation of group 1 capsular polysaccharide in Escherichia coli serotype K30. Structural and functional analysis of the outer membrane lipoprotein Wza. J Biol Chem (2003) 1.37
The 3D structure of a periplasm-spanning platform required for assembly of group 1 capsular polysaccharides in Escherichia coli. Proc Natl Acad Sci U S A (2007) 1.36
Structure and function of both domains of ArnA, a dual function decarboxylase and a formyltransferase, involved in 4-amino-4-deoxy-L-arabinose biosynthesis. J Biol Chem (2005) 1.34
Structural aspects of non-ribosomal peptide biosynthesis. Curr Opin Struct Biol (2004) 1.34
Effect of rotavirus strain on the murine model of biliary atresia. J Virol (2006) 1.31
Crystal structures of Mycobacteria tuberculosis and Klebsiella pneumoniae UDP-galactopyranose mutase in the oxidised state and Klebsiella pneumoniae UDP-galactopyranose mutase in the (active) reduced state. J Mol Biol (2005) 1.30
Pulsed electron-electron double resonance: beyond nanometre distance measurements on biomacromolecules. Biochem J (2011) 1.29
Base-specific spin-labeling of RNA for structure determination. Nucleic Acids Res (2007) 1.28
The histone chaperones Nap1 and Vps75 bind histones H3 and H4 in a tetrameric conformation. Mol Cell (2011) 1.26
Novel inhibitors of an emerging target in Mycobacterium tuberculosis; substituted thiazolidinones as inhibitors of dTDP-rhamnose synthesis. Bioorg Med Chem Lett (2003) 1.25
Adenylate-forming enzymes. Curr Opin Struct Biol (2009) 1.23
Structure of the heterotrimeric PCNA from Sulfolobus solfataricus. Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 1.21
Structure of the DNA repair helicase hel308 reveals DNA binding and autoinhibitory domains. J Biol Chem (2007) 1.21
Three-dimensional structure of Wza, the protein required for translocation of group 1 capsular polysaccharide across the outer membrane of Escherichia coli. J Biol Chem (2004) 1.21
AcsD catalyzes enantioselective citrate desymmetrization in siderophore biosynthesis. Nat Chem Biol (2009) 1.21
Probing the (H3-H4)2 histone tetramer structure using pulsed EPR spectroscopy combined with site-directed spin labelling. Nucleic Acids Res (2009) 1.20
The cyanobactin heterocyclase enzyme: a processive adenylase that operates with a defined order of reaction. Angew Chem Int Ed Engl (2013) 1.20
Hypertension in people with type 2 diabetes: Update on pharmacologic management. Can Fam Physician (2011) 1.17
A case-control study to determine risk factors for hospitalization for rotavirus gastroenteritis in U.S. children. Pediatr Infect Dis J (2006) 1.13
The fluorinase from Streptomyces cattleya is also a chlorinase. Angew Chem Int Ed Engl (2006) 1.13
Harmonization of guidelines for the prevention and treatment of cardiovascular disease: the C-CHANGE Initiative. CMAJ (2011) 1.12
Orexin receptors: multi-functional therapeutic targets for sleeping disorders, eating disorders, drug addiction, cancers and other physiological disorders. Cell Signal (2013) 1.11
Periplasmic protein-protein contacts in the inner membrane protein Wzc form a tetrameric complex required for the assembly of Escherichia coli group 1 capsules. J Biol Chem (2005) 1.11
PELDOR spectroscopy distance fingerprinting of the octameric outer-membrane protein Wza from Escherichia coli. Angew Chem Int Ed Engl (2009) 1.10
Hypertension in diabetes: a call to action. Can J Cardiol (2009) 1.10
RmlC, a C3' and C5' carbohydrate epimerase, appears to operate via an intermediate with an unusual twist boat conformation. J Mol Biol (2006) 1.09
Toward a structural understanding of the dehydratase mechanism. Structure (2002) 1.08
MAPK signaling contributes to rotaviral-induced cholangiocyte injury and viral replication. Surgery (2007) 1.08
Cholangiocyte expression of alpha2beta1-integrin confers susceptibility to rotavirus-induced experimental biliary atresia. Am J Physiol Gastrointest Liver Physiol (2008) 1.07
NMR spectroscopic and theoretical analysis of a spontaneously formed Lys-Asp isopeptide bond. Angew Chem Int Ed Engl (2010) 1.06
Staphylococcus aureus Staphopain A inhibits CXCR2-dependent neutrophil activation and chemotaxis. EMBO J (2012) 1.06
Variation on a theme of SDR. dTDP-6-deoxy-L- lyxo-4-hexulose reductase (RmlD) shows a new Mg2+-dependent dimerization mode. Structure (2002) 1.06
Structural and kinetic characterization of quinolinate phosphoribosyltransferase (hQPRTase) from homo sapiens. J Mol Biol (2007) 1.04
Binding of manganese(II) to a tertiary stabilized hammerhead ribozyme as studied by electron paramagnetic resonance spectroscopy. RNA (2005) 1.04
The rhesus rotavirus gene encoding VP4 is a major determinant in the pathogenesis of biliary atresia in newborn mice. J Virol (2011) 1.04
Conformational state of the MscS mechanosensitive channel in solution revealed by pulsed electron-electron double resonance (PELDOR) spectroscopy. Proc Natl Acad Sci U S A (2012) 1.03
PELDOR measurements on a nitroxide-labeled Cu(II) porphyrin: orientation selection, spin-density distribution, and conformational flexibility. J Phys Chem A (2008) 1.03
Double aortic arch masquerading as asthma for thirty years. Respiration (2002) 1.02
Studying biomolecular complexes with pulsed electron-electron double resonance spectroscopy. Biochem Soc Trans (2011) 1.02
The discovery of new cyanobactins from Cyanothece PCC 7425 defines a new signature for processing of patellamides. Chembiochem (2012) 1.02
Structural, mechanistic and regulatory studies of serine palmitoyltransferase. Biochem Soc Trans (2012) 1.02
Potentiometric analysis of UDP-galactopyranose mutase: stabilization of the flavosemiquinone by substrate. Biochemistry (2003) 1.02
Structure and function of GDP-mannose-3',5'-epimerase: an enzyme which performs three chemical reactions at the same active site. J Am Chem Soc (2005) 1.02
A novel outer membrane protein, Wzi, is involved in surface assembly of the Escherichia coli K30 group 1 capsule. J Bacteriol (2003) 1.01
An efficient method for the in vitro production of azol(in)e-based cyclic peptides. Angew Chem Int Ed Engl (2014) 0.99
Mechanism of enzymatic fluorination in Streptomyces cattleya. J Am Chem Soc (2007) 0.98
Trityl radicals: spin labels for nanometer-distance measurements. Chemistry (2012) 0.98
The chemical basis of serine palmitoyltransferase inhibition by myriocin. J Am Chem Soc (2013) 0.98
Live attenuated human rotavirus vaccine, RIX4414, provides clinical protection in infants against rotavirus strains with and without shared G and P genotypes: integrated analysis of randomized controlled trials. Pediatr Infect Dis J (2009) 0.98
Structural insights into regioselectivity in the enzymatic chlorination of tryptophan. J Mol Biol (2009) 0.98
New insights into the mechanism of enzymatic chlorination of tryptophan. Angew Chem Int Ed Engl (2008) 0.97
The structure of NADH in the enzyme dTDP-d-glucose dehydratase (RmlB). J Am Chem Soc (2003) 0.97
The AEROPATH project targeting Pseudomonas aeruginosa: crystallographic studies for assessment of potential targets in early-stage drug discovery. Acta Crystallogr Sect F Struct Biol Cryst Commun (2012) 0.97
Periplasmic export machines for outer membrane assembly. Curr Opin Struct Biol (2008) 0.96
Alcohol-induced facial dysmorphology in C57BL/6 mouse models of fetal alcohol spectrum disorder. Alcohol (2010) 0.96
A dimeric Rep protein initiates replication of a linear archaeal virus genome: implications for the Rep mechanism and viral replication. J Virol (2010) 0.96
Crystallization and preliminary X-ray diffraction analysis of Wza outer-membrane lipoprotein from Escherichia coli serotype O9a:K30. Acta Crystallogr D Biol Crystallogr (2004) 0.95
Sugar nucleotide recognition by Klebsiella pneumoniae UDP-D-galactopyranose mutase: fluorinated substrates, kinetics and equilibria. Org Biomol Chem (2009) 0.95
Crystal structures of Wzb of Escherichia coli and CpsB of Streptococcus pneumoniae, representatives of two families of tyrosine phosphatases that regulate capsule assembly. J Mol Biol (2009) 0.94
Structural and mechanistic basis of bacterial sugar nucleotide-modifying enzymes. Biochemistry (2003) 0.93
Probing the acceptor substrate binding site of Trypanosoma cruzi trans-sialidase with systematically modified substrates and glycoside libraries. Org Biomol Chem (2011) 0.93
Structural plasticity of histones H3-H4 facilitates their allosteric exchange between RbAp48 and ASF1. Nat Struct Mol Biol (2012) 0.92
Structure of PatF from Prochloron didemni. Acta Crystallogr Sect F Struct Biol Cryst Commun (2013) 0.92
Changing the regioselectivity of the tryptophan 7-halogenase PrnA by site-directed mutagenesis. Angew Chem Int Ed Engl (2011) 0.92
The structural basis of chain length control in Rv1086. J Mol Biol (2008) 0.91
Altered antibiotic transport in OmpC mutants isolated from a series of clinical strains of multi-drug resistant E. coli. PLoS One (2011) 0.91
Low resolution structure of a bacterial SLC26 transporter reveals dimeric stoichiometry and mobile intracellular domains. J Biol Chem (2011) 0.90
Displacement of the canonical single-stranded DNA-binding protein in the Thermoproteales. Proc Natl Acad Sci U S A (2011) 0.90
Adjustment and coping in spousal caregivers following a traumatic spinal cord injury: an interpretative phenomenological analysis. J Health Psychol (2011) 0.90