Immune approaches for the prevention of breast milk transmission of HIV-1.

PubWeight™: 0.75‹?›

🔗 View Article (PMC 3709581)

Published in Adv Exp Med Biol on January 01, 2012

Authors

Barbara Lohman-Payne1, Jennifer Slyker, Sarah L Rowland-Jones

Author Affiliations

1: Department of Pediatrics and Child Health, University of Nairobi, Nairobi, Kenya, 00202. blpayne@iconnect.co.ke

Articles cited by this

Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand. N Engl J Med (2009) 28.62

Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial. Lancet (2008) 19.65

Mortality of infected and uninfected infants born to HIV-infected mothers in Africa: a pooled analysis. Lancet (2004) 16.28

HIV-1 vaccine-induced immunity in the test-of-concept Step Study: a case-cohort analysis. Lancet (2008) 8.37

Randomized, double-blind, placebo-controlled efficacy trial of a bivalent recombinant glycoprotein 120 HIV-1 vaccine among injection drug users in Bangkok, Thailand. J Infect Dis (2006) 7.98

Effector memory T cell responses are associated with protection of rhesus monkeys from mucosal simian immunodeficiency virus challenge. Nat Med (2009) 7.33

Immune control of an SIV challenge by a T-cell-based vaccine in rhesus monkeys. Nature (2008) 6.17

Late postnatal transmission of HIV-1 in breast-fed children: an individual patient data meta-analysis. J Infect Dis (2004) 5.93

Maternal alloantigens promote the development of tolerogenic fetal regulatory T cells in utero. Science (2008) 5.76

Neonatal adaptive immunity comes of age. Nat Rev Immunol (2004) 5.31

Innate immunity of the newborn: basic mechanisms and clinical correlates. Nat Rev Immunol (2007) 5.20

Live attenuated, multiply deleted simian immunodeficiency virus causes AIDS in infant and adult macaques. Nat Med (1999) 3.86

Viral load and disease progression in infants infected with human immunodeficiency virus type 1. Women and Infants Transmission Study Group. N Engl J Med (1997) 3.71

Effect of Plasmodium falciparum malaria on concentration of HIV-1-RNA in the blood of adults in rural Malawi: a prospective cohort study. Lancet (2005) 3.48

Child mortality according to maternal and infant HIV status in Zimbabwe. Pediatr Infect Dis J (2007) 3.40

Newborns develop a Th1-type immune response to Mycobacterium bovis bacillus Calmette-Guérin vaccination. J Immunol (1999) 2.94

High frequency of rapid immunological progression in African infants infected in the era of perinatal HIV prophylaxis. AIDS (2007) 2.73

HIV-specific cytotoxic T-cell activity in an HIV-exposed but uninfected infant. Lancet (1993) 2.71

Changes in plasma human immunodeficiency virus type 1 RNA associated with herpes simplex virus reactivation and suppression. J Infect Dis (2002) 2.67

Cord blood CD4(+)CD25(+)-derived T regulatory cell lines express FoxP3 protein and manifest potent suppressor function. Blood (2004) 2.63

Attrition of T cell memory: selective loss of LCMV epitope-specific memory CD8 T cells following infections with heterologous viruses. Immunity (1999) 2.55

Transplacental priming of the human immune system to environmental allergens: universal skewing of initial T cell responses toward the Th2 cytokine profile. J Immunol (1998) 2.53

Cytomegalovirus infection and HIV-1 disease progression in infants born to HIV-1-infected women. Pediatric Pulmonary and Cardiovascular Complications of Vertically Transmitted HIV Infection Study Group. N Engl J Med (1999) 2.51

Complete protection of neonatal rhesus macaques against oral exposure to pathogenic simian-human immunodeficiency virus by human anti-HIV monoclonal antibodies. J Infect Dis (2004) 2.47

Association of levels of HIV-1-infected breast milk cells and risk of mother-to-child transmission. J Infect Dis (2004) 2.45

The impact of active herpes simplex virus infection on human immunodeficiency virus load. J Infect Dis (1997) 2.31

Postnatal passive immunization of neonatal macaques with a triple combination of human monoclonal antibodies against oral simian-human immunodeficiency virus challenge. J Virol (2001) 2.30

Predictors of early mortality in a cohort of human immunodeficiency virus type 1-infected african children. Pediatr Infect Dis J (2004) 2.30

Longitudinal analysis of human immunodeficiency virus type 1 RNA in breast milk and of its relationship to infant infection and maternal disease. J Infect Dis (2003) 2.10

The development of the immune system during pregnancy and early life. Allergy (2000) 2.04

Influence of Mycobacterium bovis bacillus Calmette-Guérin on antibody and cytokine responses to human neonatal vaccination. J Immunol (2002) 1.98

Mother-to-child transmission of human immunodeficiency virus type 1: report from the Nairobi Study. J Infect Dis (1994) 1.94

Immune responses to measles and mumps vaccination of infants at 6, 9, and 12 months. J Infect Dis (2001) 1.90

Cytotoxic T lymphocyte responses in the peripheral blood of children born to human immunodeficiency virus-1-infected mothers. Eur J Immunol (1992) 1.89

Acute cytomegalovirus infection in Kenyan HIV-infected infants. AIDS (2009) 1.87

Mature CD8(+) T lymphocyte response to viral infection during fetal life. J Clin Invest (2003) 1.85

Regulation of T cell responses in the developing human fetus. J Immunol (2006) 1.78

The effect of Plasmodium falciparum malaria on HIV-1 RNA blood plasma concentration. AIDS (1999) 1.76

Strong HIV-1-specific T cell responses in HIV-1-exposed uninfected infants and neonates revealed after regulatory T cell removal. PLoS One (2006) 1.73

Comparison of human immunodeficiency virus type 1 viral loads in Kenyan women, men, and infants during primary and early infection. J Virol (2003) 1.72

Passive immunization of newborn rhesus macaques prevents oral simian immunodeficiency virus infection. J Infect Dis (1998) 1.71

Attenuated poxvirus-based simian immunodeficiency virus (SIV) vaccines given in infancy partially protect infant and juvenile macaques against repeated oral challenge with virulent SIV. J Acquir Immune Defic Syndr (2005) 1.68

Natural history of vertically acquired human immunodeficiency virus-1 infection. The European Collaborative Study. Pediatrics (1994) 1.63

Virus levels in untreated African infants infected with human immunodeficiency virus type 1. J Infect Dis (1999) 1.63

HV-1-specific cytotoxic T lymphocytes and breast milk HIV-1 transmission. J Infect Dis (2009) 1.57

Breast-feeding and Transmission of HIV-1. J Acquir Immune Defic Syndr (2004) 1.56

Immunization of newborn rhesus macaques with simian immunodeficiency virus (SIV) vaccines prolongs survival after oral challenge with virulent SIVmac251. J Virol (2003) 1.53

Defective antigen-presenting cell function in human neonates. Clin Immunol (2006) 1.38

Timing of mother-to-child transmission of HIV-1 and infant mortality in the first 6 months of life in Harare, Zimbabwe. AIDS (2004) 1.37

Pediatric viral human immunodeficiency virus type 1 RNA levels, timing of infection, and disease progression in African HIV-1-infected children. Pediatrics (2003) 1.32

Cytomegalovirus infection in Gambian infants leads to profound CD8 T-cell differentiation. J Virol (2007) 1.26

Congenital cytomegalovirus infection in infants infected with human immunodeficiency virus type 1. Pediatr Infect Dis J (1996) 1.24

T-helper cell responses to HIV envelope peptides in cord blood: protection against intrapartum and breast-feeding transmission. AIDS (2001) 1.23

Association of human immunodeficiency virus (HIV) load early in life with disease progression among HIV-infected infants. New York City Perinatal HIV Transmission Collaborative Study Group. J Infect Dis (1998) 1.22

Rapid virus dissemination in infant macaques after oral simian immunodeficiency virus exposure in the presence of local innate immune responses. J Virol (2006) 1.19

Vaccination of pregnant macaques protects newborns against mucosal simian immunodeficiency virus infection. J Infect Dis (1996) 1.17

CMV as a cofactor enhancing progression of AIDS. J Clin Virol (2006) 1.16

HIV-1 vaccine induced immune responses in newborns of HIV-1 infected mothers. AIDS (2006) 1.15

Suppression of SIV-specific CD4+ T cells by infant but not adult macaque regulatory T cells: implications for SIV disease progression. J Exp Med (2007) 1.10

The detection of cytomegalovirus DNA in maternal plasma is associated with mortality in HIV-1-infected women and their infants. AIDS (2009) 1.09

Rapid progression of HIV disease in children with cytomegalovirus DNAemia. AIDS (1996) 1.05

Care of human immunodeficiency virus-infected children in developing countries. International Working Group on Mother-to-Child Transmission of HIV. Pediatr Infect Dis J (1998) 1.01

Safety and immunogenicity of attenuated Salmonella enterica serovar Typhimurium delivering an HIV-1 Gag antigen via the Salmonella Type III secretion system. Vaccine (2006) 1.00

Cytomegalovirus and Epstein-Barr virus in breast milk are associated with HIV-1 shedding but not with mastitis. AIDS (2008) 0.99

HIV-1 prophylactic vaccine comprised of topical DermaVir prime and protein boost elicits cellular immune responses and controls pathogenic R5 SHIV162P3. Virology (2007) 0.98

Decreased interleukin-10 production by neonatal monocytes and T cells: relationship to decreased production and expression of tumor necrosis factor-alpha and its receptors. Pediatr Res (1996) 0.98

Time dependence of protective post-exposure prophylaxis with human monoclonal antibodies against pathogenic SHIV challenge in newborn macaques. Virology (2006) 0.97

Comparison of systemic and mucosal delivery of 2 canarypox virus vaccines expressing either HIV-1 genes or the gene for rabies virus G protein. J Infect Dis (2004) 0.97

Cytotoxic T lymphocyte activity and CD8 subpopulations in children at risk of HIV infection. Clin Exp Immunol (1994) 0.95

What infants and breasts can teach us about natural protection from HIV infection. J Infect Dis (2010) 0.95

Expression of HIV receptors, alternate receptors and co-receptors on tonsillar epithelium: implications for HIV binding and primary oral infection. Virol J (2006) 0.95

The effect of placental malaria infection on cord blood and maternal immunoregulatory responses at birth. Eur J Immunol (2010) 0.95

Induction of systemic HIV-1-specific cellular immune responses by oral exposure in the uninfected partner of discordant couples. AIDS (2010) 0.94

Overview of the development and current use of CRM(197) conjugate vaccines for pediatric use. Vaccine (2010) 0.94

Mucosal HIV vaccines: a holy grail or a dud? Vaccine (2010) 0.87

Infants with late breast milk acquisition of HIV-1 generate interferon-gamma responses more rapidly than infants with early peripartum acquisition. Clin Exp Immunol (2009) 0.85

Cytokine production differs in children and adults. Pediatr Res (1997) 0.85

The nature and consequences of intra- and inter-vaccine interference. J Comp Pathol (2007) 0.84

Orally exposed uninfected individuals have systemic anti-HIV responses associating with partners' viral load. AIDS (2010) 0.82

Articles by these authors

Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections. Nat Med (2002) 10.03

Immune activation and CD8+ T-cell differentiation towards senescence in HIV-1 infection. PLoS Biol (2004) 3.20

Characterization of CD4(+) CTLs ex vivo. J Immunol (2002) 3.10

Polyfunctional T cell responses are a hallmark of HIV-2 infection. Eur J Immunol (2008) 2.59

Cross-reactive cytotoxic T lymphocytes against a HIV-1 p24 epitope in slow progressors with B*57. AIDS (2002) 1.92

Lessons from the study of T-cell differentiation in persistent human virus infection. Semin Immunol (2004) 1.89

Acute cytomegalovirus infection in Kenyan HIV-infected infants. AIDS (2009) 1.87

Mature CD8(+) T lymphocyte response to viral infection during fetal life. J Clin Invest (2003) 1.85

A human immunodeficiency virus 1 (HIV-1) clade A vaccine in clinical trials: stimulation of HIV-specific T-cell responses by DNA and recombinant modified vaccinia virus Ankara (MVA) vaccines in humans. J Gen Virol (2004) 1.80

Increased expression of the NK cell receptor KLRG1 by virus-specific CD8 T cells during persistent antigen stimulation. J Virol (2005) 1.74

HIV-2: the forgotten AIDS virus. Trends Microbiol (2008) 1.66

HIV-specific cytotoxic T cells from long-term survivors select a unique T cell receptor. J Exp Med (2004) 1.60

HV-1-specific cytotoxic T lymphocytes and breast milk HIV-1 transmission. J Infect Dis (2009) 1.57

Premature ageing of the immune system: the cause of AIDS? Trends Immunol (2002) 1.55

Polyfunctional CD4(+) and CD8(+) T cell responses to tuberculosis antigens in HIV-1-infected patients before and after anti-retroviral treatment. J Immunol (2010) 1.45

Dynamics of T cell responses in HIV infection. J Immunol (2002) 1.44

Delaying bacillus Calmette-Guérin vaccination from birth to 4 1/2 months of age reduces postvaccination Th1 and IL-17 responses but leads to comparable mycobacterial responses at 9 months of age. J Immunol (2010) 1.42

Modulation of interleukin-7 receptor expression characterizes differentiation of CD8 T cells specific for HIV, EBV and CMV. AIDS (2005) 1.40

Maintenance of HIV-specific CD4+ T cell help distinguishes HIV-2 from HIV-1 infection. J Immunol (2006) 1.36

The assessment of antigen-specific CD8+ T cells through the combination of MHC class I tetramer and intracellular staining. J Immunol Methods (2002) 1.28

Lack of KIR3DS1 binding to MHC class I Bw4 tetramers in complex with CD8+ T cell epitopes. AIDS Res Hum Retroviruses (2007) 1.23

Deep analysis of cellular transcriptomes - LongSAGE versus classic MPSS. BMC Genomics (2007) 1.21

Timing of CD8+ T cell responses in relation to commencement of capillary leakage in children with dengue. J Immunol (2010) 1.20

Viral coinfections among African children infected with human immunodeficiency virus type 1. Clin Infect Dis (2003) 1.18

High frequency of HIV mutations associated with HLA-C suggests enhanced HLA-C-restricted CTL selective pressure associated with an AIDS-protective polymorphism. J Immunol (2012) 1.16

Association between maternal and infant class I and II HLA alleles and of their concordance with the risk of perinatal HIV type 1 transmission. AIDS Res Hum Retroviruses (2002) 1.14

Human leukocyte antigen (HLA) B*18 and protection against mother-to-child HIV type 1 transmission. AIDS Res Hum Retroviruses (2004) 1.11

Strong TCR conservation and altered T cell cross-reactivity characterize a B*57-restricted immune response in HIV-1 infection. J Immunol (2006) 1.09

The detection of cytomegalovirus DNA in maternal plasma is associated with mortality in HIV-1-infected women and their infants. AIDS (2009) 1.09

Identification of H5N1-specific T-cell responses in a high-risk cohort in vietnam indicates the existence of potential asymptomatic infections. J Infect Dis (2011) 1.05

Correlates of delayed disease progression in HIV-1-infected Kenyan children. J Immunol (2005) 1.05

Quantitative ex vivo analysis of functional virus-specific CD8 T lymphocytes in the blood and genital tract of HIV-infected women. AIDS (2003) 1.02

Extensive HLA-driven viral diversity following a narrow-source HIV-1 outbreak in rural China. Blood (2011) 1.01

The T cell surface--how well do we know it? Immunity (2003) 1.01

HIV-1 Env-specific cytotoxic T-lymphocyte responses in exposed, uninfected Kenyan sex workers: a prospective analysis. AIDS (2004) 1.00

The tuberculin skin test (TST) is affected by recent BCG vaccination but not by exposure to non-tuberculosis mycobacteria (NTM) during early life. PLoS One (2010) 1.00

Functional discrepancies in HIV-specific CD8+ T-lymphocyte populations are related to plasma virus load. J Clin Immunol (2002) 0.99

Immunisation with recombinant modified vaccinia virus Ankara expressing HIV-1 gag in HIV-1-infected subjects stimulates broad functional CD4+ T cell responses. Eur J Immunol (2006) 0.96

Antiretroviral Therapy for HIV-2 Infection: Recommendations for Management in Low-Resource Settings. AIDS Res Treat (2011) 0.96

Characterization of an HLA-C-restricted CTL response in chronic HIV infection. Eur J Immunol (2010) 0.93

Dendritic cells are less susceptible to human immunodeficiency virus type 2 (HIV-2) infection than to HIV-1 infection. J Virol (2007) 0.92

Epitope mapping of broadly neutralizing HIV-2 human monoclonal antibodies. J Virol (2012) 0.90

Examination of influenza specific T cell responses after influenza virus challenge in individuals vaccinated with MVA-NP+M1 vaccine. PLoS One (2013) 0.89

Correlates of T-cell-mediated viral control and phenotype of CD8(+) T cells in HIV-2, a naturally contained human retroviral infection. Blood (2013) 0.89

Modified vaccinia Ankara expressing HIVA antigen stimulates HIV-1-specific CD8 T cells in ELISpot assays of HIV-1 exposed infants. Vaccine (2005) 0.89

Persistent HIV-1-specific cellular responses despite prolonged therapeutic viral suppression. AIDS (2002) 0.89

HLA typing in a Kenyan cohort identifies novel class I alleles that restrict cytotoxic T-cell responses to local HIV-1 clades. AIDS (2002) 0.88

Influence of HLA class I and HLA-KIR compound genotypes on HIV-2 infection and markers of disease progression in a Manjako community in West Africa. J Virol (2010) 0.87

The antiviral efficacy of HIV-specific CD8⁺ T-cells to a conserved epitope is heavily dependent on the infecting HIV-1 isolate. PLoS Pathog (2011) 0.87

Prevalence and magnitude of human immunodeficiency virus (HIV) type 1-specific lymphocyte responses in breast milk from HIV-1-seropositive women. J Infect Dis (2003) 0.87

Structural features underlying T-cell receptor sensitivity to concealed MHC class I micropolymorphisms. Proc Natl Acad Sci U S A (2012) 0.86

Comprehensive analysis of HIV Gag-specific IFN-gamma response in HIV-1- and HIV-2-infected asymptomatic patients from a clinical cohort in The Gambia. Eur J Immunol (2008) 0.86

The impact of HIV-1 infection and exposure on natural killer (NK) cell phenotype in Kenyan infants during the first year of life. Front Immunol (2012) 0.86

HIV-1-specific CD8 T cell responses in a pediatric slow progressor infected as a premature neonate. AIDS (2002) 0.85

Acute cytomegalovirus infection is associated with increased frequencies of activated and apoptosis-vulnerable T cells in HIV-1-infected infants. J Virol (2012) 0.85

Phenotypic characterization of HIV-specific CD8+ T cells during early and chronic infant HIV-1 infection. PLoS One (2011) 0.84

A novel immunodominant CD8+ T cell response restricted by a common HLA-C allele targets a conserved region of Gag HIV-1 clade CRF01_AE infected Thais. PLoS One (2011) 0.83

HIV and chemokine binding to red blood cells--DARC matters. Cell Host Microbe (2008) 0.82

Gonococcal cervicitis is associated with reduced systemic CD8+ T cell responses in human immunodeficiency virus type 1-infected and exposed, uninfected sex workers. J Infect Dis (2002) 0.81

Downregulation of the T-cell receptor by human immunodeficiency virus type 2 Nef does not protect against disease progression. J Virol (2009) 0.81

A phase I randomized clinical trial of candidate human immunodeficiency virus type 1 vaccine MVA.HIVA administered to Gambian infants. PLoS One (2013) 0.80

Immune-based approaches to the prevention of mother-to-child transmission of HIV-1: active and passive immunization. Clin Perinatol (2010) 0.80

An underestimated lentivirus model: what can HIV-2 research contribute to the development of an effective HIV-1 vaccine? Expert Rev Anti Infect Ther (2011) 0.80

The HIV protease inhibitor indinavir reduces immature dendritic cell transendothelial migration. Eur J Immunol (2003) 0.79

HLA correlates in a cohort of slow progressors from China: effects on HIV-1 disease progression. AIDS (2013) 0.78

Differential remodeling of a T-cell transcriptome following CD8- versus CD3-induced signaling. Cell Res (2008) 0.77

Functional differences exist between TNFα promoters encoding the common -237G SNP and the rarer HLA-B*5701-linked A variant. PLoS One (2012) 0.77

HIV-1 subtype distribution in the Gambia and the significant presence of CRF49_cpx, a novel circulating recombinant form. Retrovirology (2010) 0.77

Identification of a novel HLA B*57 restricted cytotoxic T-lymphocyte epitope within HIV-1 rev. AIDS (2006) 0.76

Clinical predictors cannot replace biological predictors in HIV-2 infection in a community setting in West Africa. Int J Infect Dis (2012) 0.76

HIV: Bad news for stop--start therapy? Nature (2002) 0.75

Natural killer cell and T-cell subset distributions and activation influence susceptibility to perinatal HIV-1 infection. AIDS (2014) 0.75

Predicting the extinction of HIV-2 in rural Guinea-Bissau. AIDS (2015) 0.75

HLA Correlates of Long-Term Survival in Vertically Infected HIV-1-Positive Adolescents in Harare, Zimbabwe. AIDS Res Hum Retroviruses (2015) 0.75

Cytomegalovirus viraemia is associated with poor growth and T-cell activation with an increased burden in HIV-exposed uninfected infants. AIDS (2017) 0.75