Published in Br J Clin Pharmacol on April 01, 1974
Effect of a new adrenergic beta-blocking agent (ICI 50,172) on heart rate in relation to its blood levels. Int Z Klin Pharmakol Ther Toxikol (1968) 4.92
Blood levels of practolol following intravenous administration. Br J Pharmacol (1970) 1.61
The metabolism and distribution of the selective adrenergic beta blocking agent, practolol. J Pharmacol Exp Ther (1970) 1.40
The absorption and excretion of carbenoxolone in man. J Pharm Pharmacol (1970) 1.22
The effect of age on plasma levels of propranolol and practolol in man. Br J Clin Pharmacol (1975) 2.28
Cardiac and pulmonary effects of acebutolol. Lancet (1975) 2.12
Studies of cardioselectivity and partial agonist activity in beta-adrenoceptor blockade comparing effects on heart rate and peak expiratory flow rate during exercise. Br J Clin Pharmacol (1978) 2.07
New approach to assessment of cardioselectivity of beta-blocking drugs. Br Med J (1974) 2.06
An investigation into the cardiac and pulmonary beta-adrenoceptor blocking activity of ICI 66,082 in man. Br J Clin Pharmacol (1975) 2.05
Selectivity of beta adrenoreceptor antagonist drugs assessed by histamine bronchial provocation. Clin Pharmacol Ther (1979) 1.60
Disposition of oral metronidazole in hepatic cirrhosis and in hepatosplenic schistosomiasis. Gut (1982) 1.59
Absorption of propranolol and practolol in Coeliac disease. Gut (1976) 1.55
Hospital antibiotic prescribing successfully modified by 'immediate concurrent feedback'. Br J Clin Pharmacol (1996) 1.51
Meta-analysis of large outcome trials of angiotensin receptor blockers in hypertension. J Hum Hypertens (2006) 1.47
Thrombolytic therapy for acute ischaemic stroke: is the hype justified? Hong Kong Med J (2011) 1.40
A rapid and specific semi-micro method involving high-pressure liquid chromatography for the assay of metronidazole in plasma, saliva, serum, urine and whole blood. Br J Clin Pharmacol (1980) 1.38
Glycerol infusion rates warrant caution. Stroke (1991) 1.38
Acebutolol: ten years of experience. Am Heart J (1985) 1.31
Beclomethasone dipropionate enemas for treating inflammatory bowel disease without producing Cushing's syndrome or hypothalamic pituitary adrenal suppression. Lancet (1982) 1.25
Hepatic veno-occlusive disease due to toxic alkaloid herbal tea. Lancet (1983) 1.20
Proceedings: The influence of urine pH on the renal excretion of practolol and propranolol. Br J Pharmacol (1973) 1.20
Insidiously evolving, occult drug interaction involving warfarin and amiodarone. BMJ (1996) 1.15
Natriuretic peptides--relevance in cardiovascular disease. JAMA (1998) 1.14
An investigation of the relationship between beta-adrenoceptor blockade and plasma practolol concentration in man. Eur J Clin Pharmacol (1974) 1.14
Observations on the metabolism of allyl compounds in the rat. Biochem J (1969) 1.09
Pharmacokinetics of metronidazole and its principal metabolites and their activity against Gardnerella vaginalis. Br J Vener Dis (1982) 1.06
Use of plasma levels in evaluation of procainamide dosage. Br Heart J (1974) 0.99
Beta-lactam antibiotic and beta-lactamase inhibitor combinations. JAMA (2001) 0.98
The pharmacokinetics of acebutolol in man, following the oral administration of acebutolol HCl as a single dose (400 mg), and during and after repeated oral dosing (400 mg, b.d.). Biopharm Drug Dispos (1981) 0.95
Observations on the pharmacokinetics of acebutolol. Clin Pharmacol Ther (1976) 0.93
Observations on the clinical pharmacology and plasma concentrations of diacetolol, the major human metabolite of acebutolol. Br J Clin Pharmacol (1981) 0.92
Severe digital ischaemia treated with phosphodiesterase inhibitors. Ann Rheum Dis (2004) 0.92
Absorption and antidysrhythmic activity of oral disopyramide phosphate after acute myocardial infarction. Br J Clin Pharmacol (1982) 0.91
A study of practolol elimination in all grades of chronic renal failure. Int J Clin Pharmacol Biopharm (1975) 0.90
Inability of physicians to use metered-dose inhalers. J Asthma (1997) 0.90
Pharmacokinetics, pharmacodynamics, long-term efficacy and safety of oral 1-deamino-8-D-arginine vasopressin in adult patients with central diabetes insipidus. Br J Clin Pharmacol (1996) 0.90
Lack of correlation between acetylator status and the production of the acetyl metabolite of acebutolol in man. Br J Clin Pharmacol (1978) 0.89
A study of the influence of pH on the buccal absorption and renal excretion of procainamide. Eur J Clin Pharmacol (1974) 0.89
Biosynthesis of mercapturic acids from allyl alcohol, allyl esters and acrolein. Biochem J (1973) 0.88
A high-pressure liquid chromatographic methods for the assay of ketoprofen in plasma and urine, and its application to determining the urinary excretion of free and conjugated ketoprofen following oral administrations of Orudis to man. Br J Clin Pharmacol (1981) 0.88
Treatment of acute cerebral hemorrhage with intravenous glycerol. A double-blind, placebo-controlled, randomized trial. Stroke (1992) 0.88
Variable pharmacokinetics of mexiletine. Postgrad Med J (1977) 0.87
Preliminary observations on the excretion of acebutolol and its acetyl metabolite in the urine and faeces of man. J Pharm Pharmacol (1981) 0.87
A comparison of the absorption of effervescent preparations of paracetamol and penicillin V (phenoxymethylpenicillin) with solid dose forms of these drugs. J Clin Pharmacol (1974) 0.86
Paroxetine plasma levels: lack of correlation with efficacy or adverse events. Acta Psychiatr Scand Suppl (1989) 0.86
Differences in diazepam pharmacokinetics in Chinese and white Caucasians--relation to body lipid stores. Eur J Clin Pharmacol (1987) 0.86
The firing of Dr Lundberg. JAMA (1999) 0.85
Treatment of acute cortical infarct with intravenous glycerol. A double-blind, placebo-controlled randomized trial. Stroke (1993) 0.85
Herbal tea induced hepatic veno-occlusive disease: quantification of toxic alkaloid exposure in adults. Gut (1985) 0.85
A simple and sensitive H.P.L.C. method for the assay of prochlorperazine in plasma. Br J Clin Pharmacol (1982) 0.84
Increased adrenomedullin expression in lungs in endotoxaemia. J Endocrinol (2004) 0.82
A comparison of plasma and synovial fluid profiles of standard and controlled-release formulations of ketoprofen in patients with rheumatoid arthritis. Curr Med Res Opin (1986) 0.82
Beta-adrenoceptor antagonists and respiratory function. Br J Clin Pharmacol (1978) 0.82
Intravenous metronidazole in the newborn. Arch Dis Child (1983) 0.82
Combination therapy for hypertension. Hong Kong Med J (2003) 0.82
Acebutolol and coronary artery surgery. Plasma levels following oral pre-operative treatment. Anaesthesia (1982) 0.81
The metabolic formation of mercapturic acids from allyl halides. Xenobiotica (1972) 0.81
Dementia and statins. Lancet (2001) 0.81
Selective and nonselective beta-adrenoceptor blockade in hypertension: responses to changes in posture, cold and exercise. Circulation (1982) 0.80
The biliary excretion of acebutolol in man. J Pharm Pharmacol (1976) 0.80
Polymyalgia rheumatica as the rheumatological manifestation of myelodysplastic syndrome in a Chinese patient. Br J Rheumatol (1996) 0.80
Preliminary observations on the elimination of acebutolol in severe chronic renal failure. Br J Clin Pharmacol (1976) 0.79
An investigation of "absolute plasma level effect relationships" and "absolute cardioselectivity" with respect to beta-adrenoceptor blockade. Eur J Clin Pharmacol (1977) 0.79
Worldwide variation in use of chloramphenicol. Lancet (1987) 0.79
Serum, saliva, and sputum levels of metronidazole in acute exacerbations of chronic bronchitis. Thorax (1981) 0.79
The influence of pH on the buccal absorption and plasma and renal elimination of acebutolol. Br J Clin Pharmacol (1976) 0.79
HpaII polymorphism in the atrial natriuretic peptide gene and hypertension. Am J Hypertens (1999) 0.78
A placebo-controlled study to determine the efficacy of oral disopyramide phosphate for the prophylaxis of ventricular dysrhythmias after acute myocardial infarction. Br J Clin Pharmacol (1982) 0.78
Should decisions on treatment be based on absolute benefit rather than absolute risk? N Z Med J (2001) 0.78
Comparison of digoxin versus low-dose amiodarone for ventricular rate control in patients with chronic atrial fibrillation. Clin Exp Pharmacol Physiol (2001) 0.78
Timing of prophylactic antibiotics in abdominal surgery: trial of a pre-operative versus an intra-operative first dose. Br J Surg (1989) 0.78
Chemoprophylaxis with oral amoxycillin against bacterial endocarditis: when should second doses be administered after dentistry? Br Med J (Clin Res Ed) (1986) 0.78
Application of 'flow volume curves' to assess the selectivity of beta-adrenoceptor antagonist drugs. Br J Clin Pharmacol (1978) 0.78
Cost-effectiveness analysis of applying the Cholesterol and Recurrent Events (CARE) study protocol in Hong Kong. Hong Kong Med J (2001) 0.78
M235T polymorphism of the angiotensinogen gene and hypertension in Chinese. J Hypertens (1998) 0.77
Pyrrolizidine alkaloid composition of three Chinese medicinal herbs, Eupatorium cannabinum, E. japonicum and Crotalaria assamica. Am J Chin Med (1992) 0.77
Changes in plasma concentrations of acebutolol, propranolol and indomethacin during physical exercise. Life Sci (1981) 0.77
A randomized prospective comparison of oral levofloxacin plus intraperitoneal (IP) vancomycin and IP netromycin plus IP vancomycin as primary treatment of peritonitis complicating CAPD. Perit Dial Int (1999) 0.77
Bronchodilator responses to salbutamol using diskhaler versus metered-dose inhaler. J Asthma (1998) 0.77
Preliminary study of the disposition in man of acebutolol and its metabolite, diacetolol, using a new stereoselective hplc method. J Pharm Pharmacol (1984) 0.76
Heliotropium lasiocarpum Fisch and Mey identified as cause of veno-occlusive disease due to a herbal tea. Lancet (1986) 0.76
Procainamide absorption studies to test the feasibility of using a sustained-release preparation. Br J Clin Pharmacol (1975) 0.76
The renal excretion of mexiletine (Kö 1173) under controlled conditions of urine pH. Br J Clin Pharmacol (1974) 0.76
Detection of body temperature with infrared thermography: accuracy in detection of fever. Hong Kong Med J (2012) 0.76
A class experiment in clinical pharmacology using beta-adrenoceptor antagonist drugs. Br J Clin Pharmacol (1985) 0.75
Drug treatment of cardiac failure. Can Fam Physician (1982) 0.75
Fulminant hyperpyrexia induced by bleomycin. Postgrad Med J (1989) 0.75
A simple spectrophotofluorometric method for the measurement of I.C.I. 66082 in plasma and urine. Br J Clin Pharmacol (1974) 0.75
Towards better management of chronic atrial fibrillation. Hong Kong Med J (2003) 0.75
Propranolol absorption in Crohn's disease and coeliac disease. Br Med J (1977) 0.75
Mercapturic acid formation from Allyl compounds in the rat. Biochem J (1970) 0.75
Successful resection of mycotic aneurysm of the superior mesenteric artery. Postgrad Med J (1972) 0.75
Emergency drugs. Can Med Assoc J (1981) 0.75
The influence of urine pH on the renal excretion of ICI 66082 in man. Br J Clin Pharmacol (1974) 0.75
The penetration of metronidazole into synovial fluid. Postgrad Med J (1982) 0.75
Association studies of genetic polymorphisms and complex disease. Lancet (2000) 0.75