|
1
|
Glucuronidation of dihydroartemisinin in vivo and by human liver microsomes and expressed UDP-glucuronosyltransferases.
|
Drug Metab Dispos
|
2002
|
1.70
|
|
2
|
Pharmacokinetics and efficacy of piperaquine and chloroquine in Melanesian children with uncomplicated malaria.
|
Antimicrob Agents Chemother
|
2007
|
1.64
|
|
3
|
The pharmacokinetic properties of intramuscular artesunate and rectal dihydroartemisinin in uncomplicated falciparum malaria.
|
Br J Clin Pharmacol
|
2002
|
1.48
|
|
4
|
Effect of a pharmaceutical care program on vascular risk factors in type 2 diabetes: the Fremantle Diabetes Study.
|
Diabetes Care
|
2005
|
1.41
|
|
5
|
Pharmacokinetics, pharmacodynamics, and allometric scaling of chloroquine in a murine malaria model.
|
Antimicrob Agents Chemother
|
2011
|
1.06
|
|
6
|
Pharmacokinetic comparison of two piperaquine-containing artemisinin combination therapies in Papua New Guinean children with uncomplicated malaria.
|
Antimicrob Agents Chemother
|
2012
|
0.98
|
|
7
|
In vitro interactions between piperaquine, dihydroartemisinin, and other conventional and novel antimalarial drugs.
|
Antimicrob Agents Chemother
|
2006
|
0.96
|
|
8
|
Safety and therapeutic efficacy of artesunate suppositories for treatment of malaria in children in Papua New Guinea.
|
Pediatr Infect Dis J
|
2003
|
0.94
|
|
9
|
Mechanism-based model of parasite growth and dihydroartemisinin pharmacodynamics in murine malaria.
|
Antimicrob Agents Chemother
|
2012
|
0.92
|
|
10
|
Pharmacokinetics and pharmacodynamics of piperaquine in a murine malaria model.
|
Antimicrob Agents Chemother
|
2007
|
0.90
|
|
11
|
Plasmodium berghei: parasite clearance after treatment with dihydroartemisinin in an asplenic murine malaria model.
|
Exp Parasitol
|
2007
|
0.89
|
|
12
|
Development of a pharmacodynamic model of murine malaria and antimalarial treatment with dihydroartemisinin.
|
Int J Parasitol
|
2007
|
0.86
|
|
13
|
Role of P glycoprotein in absorption of novel antimalarial drugs.
|
Antimicrob Agents Chemother
|
2006
|
0.85
|
|
14
|
Penetration of dihydroartemisinin into cerebrospinal fluid after administration of intravenous artesunate in severe falciparum malaria.
|
Antimicrob Agents Chemother
|
2003
|
0.83
|
|
15
|
Comparison of gentamicin dose estimates derived from manual calculations, the Australian 'Therapeutic Guidelines: Antibiotic' nomogram and the SeBA-GEN and DoseCalc software programs.
|
Br J Clin Pharmacol
|
2004
|
0.82
|
|
16
|
Hepatocellular bioactivation and cytotoxicity of the synthetic endoperoxide antimalarial arteflene.
|
Chem Biol Interact
|
2004
|
0.82
|
|
17
|
Pharmacokinetic properties of single-dose primaquine in Papua New Guinean children: feasibility of abbreviated high-dose regimens for radical cure of vivax malaria.
|
Antimicrob Agents Chemother
|
2013
|
0.82
|
|
18
|
Simultaneous determination of primaquine and carboxyprimaquine in plasma using solid phase extraction and LC-MS assay.
|
J Chromatogr B Analyt Technol Biomed Life Sci
|
2012
|
0.81
|
|
19
|
Modelling the time course of antimalarial parasite killing: a tour of animal and human models, translation and challenges.
|
Br J Clin Pharmacol
|
2015
|
0.79
|
|
20
|
Piperaquine pharmacodynamics and parasite viability in a murine malaria model.
|
Antimicrob Agents Chemother
|
2009
|
0.79
|
|
21
|
Synthesis and antimalarial evaluation of novel isocryptolepine derivatives.
|
Bioorg Med Chem
|
2011
|
0.79
|
|
22
|
Pharmacokinetics and safety of deferasirox in subjects with chronic kidney disease undergoing haemodialysis.
|
Nephrology (Carlton)
|
2013
|
0.78
|
|
23
|
Improving the solubility and bioavailability of dihydroartemisinin by solid dispersions and inclusion complexes.
|
Arch Pharm Res
|
2011
|
0.75
|
|
24
|
Greater use of insulin by southern European compared with Anglo-Celt patients with type 2 diabetes: the Fremantle Diabetes Study.
|
Eur J Endocrinol
|
2004
|
0.75
|