Kenneth F Ilett

Author PubWeight™ 81.31‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A trial of combination antimalarial therapies in children from Papua New Guinea. N Engl J Med 2008 4.77
2 Population pharmacokinetics of piperaquine in adults and children with uncomplicated falciparum or vivax malaria. Br J Clin Pharmacol 2004 3.48
3 Piperaquine: a resurgent antimalarial drug. Drugs 2005 2.80
4 Effects of a high-fat meal on the relative oral bioavailability of piperaquine. Antimicrob Agents Chemother 2005 2.00
5 Artemisinin-based combination therapies for uncomplicated malaria. Med J Aust 2005 1.98
6 Safety evaluation of fixed combination piperaquine plus dihydroartemisinin (Artekin) in Cambodian children and adults with malaria. Br J Clin Pharmacol 2004 1.84
7 Pharmacokinetics and efficacy of piperaquine and chloroquine in Melanesian children with uncomplicated malaria. Antimicrob Agents Chemother 2007 1.64
8 Population pharmacokinetics of artemether, lumefantrine, and their respective metabolites in Papua New Guinean children with uncomplicated malaria. Antimicrob Agents Chemother 2011 1.32
9 Measurement of piperaquine in plasma by liquid chromatography with ultraviolet absorbance detection. J Chromatogr B Analyt Technol Biomed Life Sci 2003 1.30
10 Desbutyl-lumefantrine is a metabolite of lumefantrine with potent in vitro antimalarial activity that may influence artemether-lumefantrine treatment outcome. Antimicrob Agents Chemother 2011 1.24
11 Studying drugs in human milk: time to unify the approach. J Hum Lact 2002 1.22
12 Disposition of artesunate and dihydroartemisinin after administration of artesunate suppositories in children from Papua New Guinea with uncomplicated malaria. Antimicrob Agents Chemother 2004 1.10
13 Pharmacokinetics of chloroquine and monodesethylchloroquine in pregnancy. Antimicrob Agents Chemother 2010 1.08
14 Pharmacokinetic properties of sulfadoxine-pyrimethamine in pregnant women. Antimicrob Agents Chemother 2009 1.08
15 Pharmacokinetics, pharmacodynamics, and allometric scaling of chloroquine in a murine malaria model. Antimicrob Agents Chemother 2011 1.06
16 Artesunate suppositories versus intramuscular artemether for treatment of severe malaria in children in Papua New Guinea. Antimicrob Agents Chemother 2006 1.05
17 In vitro sensitivity of Plasmodium falciparum to conventional and novel antimalarial drugs in Papua New Guinea. Trop Med Int Health 2010 1.04
18 Pharmacokinetic properties of azithromycin in pregnancy. Antimicrob Agents Chemother 2009 0.98
19 Artemisinin-naphthoquine combination therapy for uncomplicated pediatric malaria: a pharmacokinetic study. Antimicrob Agents Chemother 2012 0.98
20 Pharmacokinetic comparison of two piperaquine-containing artemisinin combination therapies in Papua New Guinean children with uncomplicated malaria. Antimicrob Agents Chemother 2012 0.98
21 Rectal administration of artemisinin derivatives for the treatment of malaria. JAMA 2007 0.97
22 In vitro interactions between piperaquine, dihydroartemisinin, and other conventional and novel antimalarial drugs. Antimicrob Agents Chemother 2006 0.96
23 Pseudoephedrine: effects on milk production in women and estimation of infant exposure via breastmilk. Br J Clin Pharmacol 2003 0.96
24 Transfer of methylamphetamine and amphetamine into breast milk following recreational use of methylamphetamine. Br J Clin Pharmacol 2009 0.95
25 Safety and therapeutic efficacy of artesunate suppositories for treatment of malaria in children in Papua New Guinea. Pediatr Infect Dis J 2003 0.94
26 Transfer of olanzapine into breast milk, calculation of infant drug dose, and effect on breast-fed infants. Am J Psychiatry 2003 0.93
27 Dose-effect study of domperidone as a galactagogue in preterm mothers with insufficient milk supply, and its transfer into milk. Br J Clin Pharmacol 2008 0.93
28 Transfer of lamotrigine into breast milk. Ann Pharmacother 2006 0.93
29 Transfer of chloroquine and desethylchloroquine across the placenta and into milk in Melanesian mothers. Br J Clin Pharmacol 2008 0.91
30 A pilot study of newer antidepressant concentrations in cord and maternal serum and possible effects in the neonate. Int J Neuropsychopharmacol 2004 0.91
31 Pharmacokinetics and pharmacodynamics of piperaquine in a murine malaria model. Antimicrob Agents Chemother 2007 0.90
32 Pharmacokinetics of dihydroartemisinin in a murine malaria model. Am J Trop Med Hyg 2008 0.89
33 Protein binding and alpha : beta anomer ratio of dihydroartemisinin in vivo. Br J Clin Pharmacol 2004 0.89
34 Assessment of the effect of mefloquine on artesunate pharmacokinetics in healthy male volunteers. Antimicrob Agents Chemother 2006 0.87
35 Methylphenidate and breast-feeding. Ann Pharmacother 2006 0.87
36 Determination of olanzapine in plasma by high-performance liquid chromatography using ultraviolet absorbance detection. J Chromatogr B Analyt Technol Biomed Life Sci 2002 0.86
37 Development of a pharmacodynamic model of murine malaria and antimalarial treatment with dihydroartemisinin. Int J Parasitol 2007 0.86
38 Transfer of the antidepressant mirtazapine into breast milk. Br J Clin Pharmacol 2006 0.85
39 Role of P glycoprotein in absorption of novel antimalarial drugs. Antimicrob Agents Chemother 2006 0.85
40 Potential chemoprotective effects of the coffee components kahweol and cafestol palmitates via modification of hepatic N-acetyltransferase and glutathione S-transferase activities. Environ Mol Mutagen 2004 0.85
41 Development of a sublingual/oral formulation of ketamine for use in neuropathic pain: Preliminary findings from a three-way randomized, crossover study. Clin Drug Investig 2009 0.84
42 Population pharmacokinetic modeling of tramadol and its O-desmethyl metabolite in plasma and breast milk. Eur J Clin Pharmacol 2011 0.84
43 Penetration of dihydroartemisinin into cerebrospinal fluid after administration of intravenous artesunate in severe falciparum malaria. Antimicrob Agents Chemother 2003 0.83
44 Evaluation of a deuterium-labeled internal standard for the measurement of sirolimus by high-throughput HPLC electrospray ionization tandem mass spectrometry. Clin Chem 2008 0.83
45 Investigation of reproductive toxicity of piperaquine in mice. Reprod Toxicol 2009 0.83
46 Estimation of desvenlafaxine transfer into milk and infant exposure during its use in lactating women with postnatal depression. Arch Womens Ment Health 2010 0.83
47 Hepatocellular bioactivation and cytotoxicity of the synthetic endoperoxide antimalarial arteflene. Chem Biol Interact 2004 0.82
48 Cyclosporin monitoring in Australasia: 2002 update of consensus guidelines. Ther Drug Monit 2002 0.82
49 CYP2D6 and CYP2C19 in Papua New Guinea: High frequency of previously uncharacterized CYP2D6 alleles and heterozygote excess. Int J Mol Epidemiol Genet 2010 0.82
50 Comparison of gentamicin dose estimates derived from manual calculations, the Australian 'Therapeutic Guidelines: Antibiotic' nomogram and the SeBA-GEN and DoseCalc software programs. Br J Clin Pharmacol 2004 0.82
51 The amount of fluvoxamine in milk is unlikely to be a cause of adverse effects in breastfed infants. J Hum Lact 2002 0.81
52 The wellbeing of infants exposed to buprenorphine via breast milk at 4 weeks of age. J Hum Lact 2014 0.81
53 Simultaneous determination of primaquine and carboxyprimaquine in plasma using solid phase extraction and LC-MS assay. J Chromatogr B Analyt Technol Biomed Life Sci 2012 0.81
54 Transfer of escitalopram and its metabolite demethylescitalopram into breastmilk. Br J Clin Pharmacol 2006 0.80
55 Pharmacokinetic properties of conventional and double-dose sulfadoxine-pyrimethamine given as intermittent preventive treatment in infancy. Antimicrob Agents Chemother 2011 0.80
56 Transfer of parecoxib and its primary active metabolite valdecoxib via transitional breastmilk following intravenous parecoxib use after cesarean delivery: a comparison of naive pooled data analysis and nonlinear mixed-effects modeling. Anesth Analg 2012 0.80
57 Use of duloxetine in pregnancy and lactation. Ann Pharmacother 2009 0.79
58 Measurement of nicotine and cotinine in human milk by high-performance liquid chromatography with ultraviolet absorbance detection. J Chromatogr B Analyt Technol Biomed Life Sci 2003 0.79
59 Piperaquine pharmacodynamics and parasite viability in a murine malaria model. Antimicrob Agents Chemother 2009 0.79
60 Toxicity related to chloroquine treatment of resistant vivax malaria. Ann Pharmacother 2003 0.79
61 Pharmacokinetics and pharmacodynamics of methadone enantiomers in hospice patients with cancer pain. Ther Drug Monit 2006 0.79
62 The selective pulmonary vasodilatory effect of inhaled DETA/NO, a novel nitric oxide donor, in ARDS-a pilot human trial. J Crit Care 2004 0.79
63 Transfer of reboxetine into breastmilk, its plasma concentrations and lack of adverse effects in the breastfed infant. Eur J Clin Pharmacol 2006 0.78
64 Investigation of target plasma concentration-effect relationships for olanzapine in schizophrenia. Ther Drug Monit 2003 0.78
65 Disposition and clinical outcome after intraperitoneal meperidine and ropivacaine administration during laparoscopic surgery. Anesth Analg 2008 0.78
66 Buprenorphine exposure in infants of opioid-dependent mothers at birth. Aust N Z J Obstet Gynaecol 2012 0.78
67 Two aerosolized nitric oxide adducts as selective pulmonary vasodilators for acute pulmonary hypertension. Chest 2003 0.77
68 The safety of aerosolized diethylenetriamine nitric oxide adduct after single-dose administration to anesthetized piglets and multiple-dose administration to conscious rats. Toxicol Appl Pharmacol 2003 0.77
69 Population PK modelling and simulation based on fluoxetine and norfluoxetine concentrations in milk: a milk concentration-based prediction model. Br J Clin Pharmacol 2014 0.77
70 Gabapentin and breastfeeding: a case report. J Hum Lact 2006 0.77
71 Optimizing the hydrolysis of codeine and morphine glucuronides in urine. Ther Drug Monit 2002 0.77
72 Olanzapine excretion in human breast milk: estimation of infant exposure. Int J Neuropsychopharmacol 2002 0.77
73 Development of a population pharmacokinetic model for parecoxib and its active metabolite valdecoxib after parenteral parecoxib administration in children. Anesthesiology 2012 0.77
74 Toxicology and pharmacokinetics of piperaquine in mice. Toxicology 2008 0.76
75 Duloxetine transfer across the placenta during pregnancy and into milk during lactation. Arch Womens Ment Health 2011 0.76
76 Inhaled diazeniumdiolates (NONOates) as selective pulmonary vasodilators. Expert Opin Investig Drugs 2002 0.76
77 Quetiapine and breast feeding. Ann Pharmacother 2007 0.76
78 Tramadol withdrawal in a neonate: only one of the clinical presentations to be anticipated... Eur J Clin Pharmacol 2009 0.75
79 Transfer of naltrexone and its metabolite 6,beta-naltrexol into human milk. J Hum Lact 2004 0.75
80 Prediction of milk/plasma concentration ratio of drugs. Ann Pharmacother 2004 0.75
81 Diethylenetriamine nitric oxide adduct relaxes precontracted mouse tracheal smooth muscle. Clin Exp Pharmacol Physiol 2003 0.75
82 Estimation of rac-amisulpride transfer into milk and of infant dose via milk during its use in a lactating woman with bipolar disorder and schizophrenia. Breastfeed Med 2010 0.75
83 Transfer of metyrapone and its metabolite, rac-metyrapol, into breast milk. J Hum Lact 2009 0.75
84 Effective clearance of Ara-U the major metabolite of cytosine arabinoside (Ara-C) by hemodialysis in a patient with lymphoma and end-stage renal failure. Cancer Chemother Pharmacol 2010 0.75
85 The ratio of polymorphonuclear leucocytes (PMN) to non-PMN cells--a novel method of assessing acute lung inflammation. Exp Toxicol Pathol 2002 0.75
86 Blood concentrations of enflurane before, during, and after hypothermic cardiopulmonary bypass. J Cardiothorac Vasc Anesth 2006 0.75
87 Therapeutic drug monitoring for busulfan in plasma during conditioning chemotherapy for autologous stem cell transplantation in relapsed primary cerebral lymphoma. Ther Drug Monit 2010 0.75