Richard L Jarvest

Author PubWeight™ 10.64^‹?›

Top papers

Rank	Title	Journal	Year	PubWeight™‹?›
1	Nanomolar inhibitors of Staphylococcus aureus methionyl tRNA synthetase with potent antibacterial activity against gram-positive pathogens.	J Med Chem	2002	1.42
2	Variable sensitivity to bacterial methionyl-tRNA synthetase inhibitors reveals subpopulations of Streptococcus pneumoniae with two distinct methionyl-tRNA synthetase genes.	Antimicrob Agents Chemother	2003	1.21
3	The antimicrobial natural product chuangxinmycin and some synthetic analogues are potent and selective inhibitors of bacterial tryptophanyl tRNA synthetase.	Bioorg Med Chem Lett	2002	0.88
4	Concise synthesis, preparative resolution, absolute configuration determination, and applications of an atropisomeric biaryl catalyst for asymmetric acylation.	J Org Chem	2003	0.87
5	Synthesis and biological evaluations of P4-benzoxaborole-substituted macrocyclic inhibitors of HCV NS3 protease.	Bioorg Med Chem Lett	2010	0.85
6	Optimization of novel acyl pyrrolidine inhibitors of hepatitis C virus RNA-dependent RNA polymerase leading to a development candidate.	J Med Chem	2007	0.83
7	Synthesis and evaluation of novel alpha-amino cyclic boronates as inhibitors of HCV NS3 protease.	Bioorg Med Chem Lett	2010	0.81
8	Synthesis and SAR of acyclic HCV NS3 protease inhibitors with novel P4-benzoxaborole moieties.	Bioorg Med Chem Lett	2011	0.80
9	Synthesis of new acylsulfamoyl benzoxaboroles as potent inhibitors of HCV NS3 protease.	Bioorg Med Chem Lett	2010	0.78
10	Discovery of novel urea-based hepatitis C protease inhibitors with high potency against protease-inhibitor-resistant mutants.	J Med Chem	2012	0.76
11	6-Alkylquinolone-3-carboxylic acid tethered to macrolides synthesis and antimicrobial profile.	Bioorg Med Chem	2010	0.76
12	Novel macrocyclic HCV NS3 protease inhibitors derived from α-amino cyclic boronates.	Bioorg Med Chem Lett	2010	0.76
13	Synthesis and antiviral activity of novel HCV NS3 protease inhibitors with P4 capping groups.	Bioorg Med Chem Lett	2012	0.75