1
|
MicroRNA signatures in human cancers.
|
Nat Rev Cancer
|
2006
|
46.29
|
2
|
A microRNA expression signature of human solid tumors defines cancer gene targets.
|
Proc Natl Acad Sci U S A
|
2006
|
40.09
|
3
|
Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia.
|
Proc Natl Acad Sci U S A
|
2002
|
32.26
|
4
|
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers.
|
Proc Natl Acad Sci U S A
|
2004
|
28.29
|
5
|
MicroRNA gene expression deregulation in human breast cancer.
|
Cancer Res
|
2005
|
27.56
|
6
|
A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemia.
|
N Engl J Med
|
2005
|
26.02
|
7
|
Unique microRNA molecular profiles in lung cancer diagnosis and prognosis.
|
Cancer Cell
|
2006
|
23.59
|
8
|
miR-15 and miR-16 induce apoptosis by targeting BCL2.
|
Proc Natl Acad Sci U S A
|
2005
|
21.51
|
9
|
MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias.
|
Proc Natl Acad Sci U S A
|
2004
|
14.59
|
10
|
An oligonucleotide microchip for genome-wide microRNA profiling in human and mouse tissues.
|
Proc Natl Acad Sci U S A
|
2004
|
13.66
|
11
|
MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma.
|
JAMA
|
2008
|
12.26
|
12
|
MicroRNA-133 controls cardiac hypertrophy.
|
Nat Med
|
2007
|
11.68
|
13
|
Pre-B cell proliferation and lymphoblastic leukemia/high-grade lymphoma in E(mu)-miR155 transgenic mice.
|
Proc Natl Acad Sci U S A
|
2006
|
10.65
|
14
|
MicroRNA expression patterns to differentiate pancreatic adenocarcinoma from normal pancreas and chronic pancreatitis.
|
JAMA
|
2007
|
9.97
|
15
|
MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B.
|
Proc Natl Acad Sci U S A
|
2007
|
9.82
|
16
|
MicroRNA signatures in human ovarian cancer.
|
Cancer Res
|
2007
|
9.45
|
17
|
MicroRNAs in Cancer.
|
Annu Rev Med
|
2009
|
9.37
|
18
|
Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures.
|
Cell Stem Cell
|
2009
|
8.62
|
19
|
The role of microRNA genes in papillary thyroid carcinoma.
|
Proc Natl Acad Sci U S A
|
2005
|
8.60
|
20
|
E2F1-regulated microRNAs impair TGFbeta-dependent cell-cycle arrest and apoptosis in gastric cancer.
|
Cancer Cell
|
2008
|
7.56
|
21
|
A microRNA signature of hypoxia.
|
Mol Cell Biol
|
2006
|
7.24
|
22
|
A microRNA DNA methylation signature for human cancer metastasis.
|
Proc Natl Acad Sci U S A
|
2008
|
7.14
|
23
|
Interferon modulation of cellular microRNAs as an antiviral mechanism.
|
Nature
|
2007
|
7.04
|
24
|
MicroRNA expression and function in cancer.
|
Trends Mol Med
|
2006
|
7.02
|
25
|
ALL-1 is a histone methyltransferase that assembles a supercomplex of proteins involved in transcriptional regulation.
|
Mol Cell
|
2002
|
6.72
|
26
|
MicroRNA expression, survival, and response to interferon in liver cancer.
|
N Engl J Med
|
2009
|
6.13
|
27
|
Targeting microRNAs in cancer: rationale, strategies and challenges.
|
Nat Rev Drug Discov
|
2010
|
6.07
|
28
|
MicroRNAs in cancer: small molecules with a huge impact.
|
J Clin Oncol
|
2009
|
5.92
|
29
|
MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1.
|
Blood
|
2009
|
5.87
|
30
|
Knockdown of ALR (MLL2) reveals ALR target genes and leads to alterations in cell adhesion and growth.
|
Mol Cell Biol
|
2006
|
5.74
|
31
|
Tcl1 expression in chronic lymphocytic leukemia is regulated by miR-29 and miR-181.
|
Cancer Res
|
2006
|
5.72
|
32
|
Relation between microRNA expression and progression and prognosis of gastric cancer: a microRNA expression analysis.
|
Lancet Oncol
|
2009
|
5.56
|
33
|
MicroRNAs 221 and 222 inhibit normal erythropoiesis and erythroleukemic cell growth via kit receptor down-modulation.
|
Proc Natl Acad Sci U S A
|
2005
|
5.54
|
34
|
Global and Hox-specific roles for the MLL1 methyltransferase.
|
Proc Natl Acad Sci U S A
|
2005
|
5.53
|
35
|
MicroRNA dysregulation in cancer: diagnostics, monitoring and therapeutics. A comprehensive review.
|
EMBO Mol Med
|
2012
|
5.46
|
36
|
Ultraconserved regions encoding ncRNAs are altered in human leukemias and carcinomas.
|
Cancer Cell
|
2007
|
5.40
|
37
|
MicroRNA expression abnormalities in pancreatic endocrine and acinar tumors are associated with distinctive pathologic features and clinical behavior.
|
J Clin Oncol
|
2006
|
5.40
|
38
|
Cyclin G1 is a target of miR-122a, a microRNA frequently down-regulated in human hepatocellular carcinoma.
|
Cancer Res
|
2007
|
5.40
|
39
|
MicroRNA signatures associated with cytogenetics and prognosis in acute myeloid leukemia.
|
Blood
|
2008
|
5.23
|
40
|
Crystal structures of Tcl1 family oncoproteins and their conserved surface features.
|
ScientificWorldJournal
|
2002
|
5.20
|
41
|
Genomic profiling of microRNA and messenger RNA reveals deregulated microRNA expression in prostate cancer.
|
Cancer Res
|
2008
|
5.16
|
42
|
MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response.
|
Proc Natl Acad Sci U S A
|
2012
|
5.07
|
43
|
MicroRNA expression in cytogenetically normal acute myeloid leukemia.
|
N Engl J Med
|
2008
|
4.91
|
44
|
Human chronic lymphocytic leukemia modeled in mouse by targeted TCL1 expression.
|
Proc Natl Acad Sci U S A
|
2002
|
4.86
|
45
|
Genomic and epigenetic alterations deregulate microRNA expression in human epithelial ovarian cancer.
|
Proc Natl Acad Sci U S A
|
2008
|
4.79
|
46
|
NF-kappaB-YY1-miR-29 regulatory circuitry in skeletal myogenesis and rhabdomyosarcoma.
|
Cancer Cell
|
2008
|
4.57
|
47
|
Identification of metastasis-related microRNAs in hepatocellular carcinoma.
|
Hepatology
|
2008
|
4.50
|
48
|
Micro-RNA profiling in kidney and bladder cancers.
|
Urol Oncol
|
2007
|
4.35
|
49
|
MiR-15a and miR-16-1 cluster functions in human leukemia.
|
Proc Natl Acad Sci U S A
|
2008
|
4.33
|
50
|
Distinctive microRNA signature of acute myeloid leukemia bearing cytoplasmic mutated nucleophosmin.
|
Proc Natl Acad Sci U S A
|
2008
|
4.26
|
51
|
miR-221 overexpression contributes to liver tumorigenesis.
|
Proc Natl Acad Sci U S A
|
2009
|
4.15
|
52
|
MicroRNA signatures in tissues and plasma predict development and prognosis of computed tomography detected lung cancer.
|
Proc Natl Acad Sci U S A
|
2011
|
4.11
|
53
|
The detection of differentially expressed microRNAs from the serum of ovarian cancer patients using a novel real-time PCR platform.
|
Gynecol Oncol
|
2008
|
4.10
|
54
|
miR-328 functions as an RNA decoy to modulate hnRNP E2 regulation of mRNA translation in leukemic blasts.
|
Cell
|
2010
|
4.07
|
55
|
CD34+ hematopoietic stem-progenitor cell microRNA expression and function: a circuit diagram of differentiation control.
|
Proc Natl Acad Sci U S A
|
2007
|
4.06
|
56
|
MicroRNAs 17-5p-20a-106a control monocytopoiesis through AML1 targeting and M-CSF receptor upregulation.
|
Nat Cell Biol
|
2007
|
4.02
|
57
|
Genetic and epigenetic silencing of microRNA-203 enhances ABL1 and BCR-ABL1 oncogene expression.
|
Cancer Cell
|
2008
|
4.01
|
58
|
Identification of microRNA-181 by genome-wide screening as a critical player in EpCAM-positive hepatic cancer stem cells.
|
Hepatology
|
2009
|
3.92
|
59
|
Clinical response and miR-29b predictive significance in older AML patients treated with a 10-day schedule of decitabine.
|
Proc Natl Acad Sci U S A
|
2010
|
3.86
|
60
|
MicroRNA fingerprints during human megakaryocytopoiesis.
|
Proc Natl Acad Sci U S A
|
2006
|
3.80
|
61
|
MicroRNAs regulate critical genes associated with multiple myeloma pathogenesis.
|
Proc Natl Acad Sci U S A
|
2008
|
3.77
|
62
|
MiR-21 is an EGFR-regulated anti-apoptotic factor in lung cancer in never-smokers.
|
Proc Natl Acad Sci U S A
|
2009
|
3.64
|
63
|
Biological functions of miR-29b contribute to positive regulation of osteoblast differentiation.
|
J Biol Chem
|
2009
|
3.62
|
64
|
Downregulation of p53-inducible microRNAs 192, 194, and 215 impairs the p53/MDM2 autoregulatory loop in multiple myeloma development.
|
Cancer Cell
|
2010
|
3.52
|
65
|
MicroRNAs in cancer.
|
Annu Rev Pathol
|
2013
|
3.50
|
66
|
MiRNAs and cancer.
|
Am J Pathol
|
2009
|
3.42
|
67
|
Familial cancer associated with a polymorphism in ARLTS1.
|
N Engl J Med
|
2005
|
3.35
|
68
|
MicroRNA expression profiling of human metastatic cancers identifies cancer gene targets.
|
J Pathol
|
2009
|
3.29
|
69
|
A microRNA signature for a BMP2-induced osteoblast lineage commitment program.
|
Proc Natl Acad Sci U S A
|
2008
|
3.29
|
70
|
MicroRNA 29b functions in acute myeloid leukemia.
|
Blood
|
2009
|
3.19
|
71
|
Akt induces enhanced myocardial contractility and cell size in vivo in transgenic mice.
|
Proc Natl Acad Sci U S A
|
2002
|
3.18
|
72
|
Methylation mediated silencing of MicroRNA-1 gene and its role in hepatocellular carcinogenesis.
|
Cancer Res
|
2008
|
3.16
|
73
|
Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia.
|
JAMA
|
2011
|
3.16
|
74
|
MicroRNAs modulate the chemosensitivity of tumor cells.
|
Mol Cancer Ther
|
2008
|
3.06
|
75
|
MicroRNA expression in squamous cell carcinoma and adenocarcinoma of the esophagus: associations with survival.
|
Clin Cancer Res
|
2009
|
3.03
|
76
|
The miR-17/92 polycistron is up-regulated in sonic hedgehog-driven medulloblastomas and induced by N-myc in sonic hedgehog-treated cerebellar neural precursors.
|
Cancer Res
|
2009
|
3.03
|
77
|
Emerging role of miR-106b-25/miR-17-92 clusters in the control of transforming growth factor beta signaling.
|
Cancer Res
|
2008
|
3.01
|
78
|
microRNA involvement in human cancer.
|
Carcinogenesis
|
2012
|
2.98
|
79
|
MicroRNAs 221 and 222 bypass quiescence and compromise cell survival.
|
Cancer Res
|
2008
|
2.97
|
80
|
Pancreatic endocrine tumors: expression profiling evidences a role for AKT-mTOR pathway.
|
J Clin Oncol
|
2009
|
2.94
|
81
|
p53 regulates epithelial-mesenchymal transition through microRNAs targeting ZEB1 and ZEB2.
|
J Exp Med
|
2011
|
2.93
|
82
|
Stem cell-like micro-RNA signature driven by Myc in aggressive liver cancer.
|
Proc Natl Acad Sci U S A
|
2010
|
2.91
|
83
|
Single-nucleotide polymorphisms inside microRNA target sites influence tumor susceptibility.
|
Cancer Res
|
2010
|
2.82
|
84
|
Reprogramming of miRNA networks in cancer and leukemia.
|
Genome Res
|
2010
|
2.65
|
85
|
Preclinical activity of a novel CRM1 inhibitor in acute myeloid leukemia.
|
Blood
|
2012
|
2.65
|
86
|
miR-155: on the crosstalk between inflammation and cancer.
|
Int Rev Immunol
|
2009
|
2.64
|
87
|
Mammalian microRNAs: a small world for fine-tuning gene expression.
|
Mamm Genome
|
2006
|
2.64
|
88
|
Stromal control of cystine metabolism promotes cancer cell survival in chronic lymphocytic leukaemia.
|
Nat Cell Biol
|
2012
|
2.59
|
89
|
Downregulation of microRNA expression in the lungs of rats exposed to cigarette smoke.
|
FASEB J
|
2008
|
2.58
|
90
|
microRNA-205 regulates HER3 in human breast cancer.
|
Cancer Res
|
2009
|
2.53
|
91
|
MicroRNA expression profiles for the NCI-60 cancer cell panel.
|
Mol Cancer Ther
|
2007
|
2.53
|
92
|
Concern
Parkin, a gene implicated in autosomal recessive juvenile parkinsonism, is a candidate tumor suppressor gene on chromosome 6q25-q27.
|
Proc Natl Acad Sci U S A
|
2003
|
2.52
|
93
|
miRNA signatures associate with pathogenesis and progression of osteosarcoma.
|
Cancer Res
|
2012
|
2.52
|
94
|
EGFR and MET receptor tyrosine kinase-altered microRNA expression induces tumorigenesis and gefitinib resistance in lung cancers.
|
Nat Med
|
2011
|
2.46
|
95
|
MicroRNA expression profiling using microarrays.
|
Nat Protoc
|
2008
|
2.44
|
96
|
Aberrant chromatin at genes encoding stem cell regulators in human mixed-lineage leukemia.
|
Genes Dev
|
2008
|
2.41
|
97
|
mRNA/microRNA gene expression profile in microsatellite unstable colorectal cancer.
|
Mol Cancer
|
2007
|
2.40
|
98
|
MicroRNA-29a regulates intestinal membrane permeability in patients with irritable bowel syndrome.
|
Gut
|
2009
|
2.39
|
99
|
Targeted deletion of Wwox reveals a tumor suppressor function.
|
Proc Natl Acad Sci U S A
|
2007
|
2.37
|
100
|
Sp1/NFkappaB/HDAC/miR-29b regulatory network in KIT-driven myeloid leukemia.
|
Cancer Cell
|
2010
|
2.37
|
101
|
MicroRNA microarray identifies Let-7i as a novel biomarker and therapeutic target in human epithelial ovarian cancer.
|
Cancer Res
|
2008
|
2.35
|
102
|
Mechanisms of microRNA deregulation in human cancer.
|
Cell Cycle
|
2008
|
2.30
|
103
|
Oncogenic role of miR-483-3p at the IGF2/483 locus.
|
Cancer Res
|
2010
|
2.30
|
104
|
A network connecting Runx2, SATB2, and the miR-23a~27a~24-2 cluster regulates the osteoblast differentiation program.
|
Proc Natl Acad Sci U S A
|
2010
|
2.29
|
105
|
MicroRNAs.
|
Cancer J
|
2008
|
2.28
|
106
|
In hepatocellular carcinoma miR-519d is up-regulated by p53 and DNA hypomethylation and targets CDKN1A/p21, PTEN, AKT3 and TIMP2.
|
J Pathol
|
2012
|
2.27
|
107
|
MicroRNAs in normal and malignant hematopoiesis.
|
Curr Opin Hematol
|
2008
|
2.23
|
108
|
Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing.
|
Proc Natl Acad Sci U S A
|
2011
|
2.21
|
109
|
MicroRNAs in the pathogenesis of cancer.
|
Semin Oncol
|
2011
|
2.15
|
110
|
SnapShot: MicroRNAs in Cancer.
|
Cell
|
2009
|
2.10
|
111
|
17-DMAG targets the nuclear factor-kappaB family of proteins to induce apoptosis in chronic lymphocytic leukemia: clinical implications of HSP90 inhibition.
|
Blood
|
2010
|
2.07
|
112
|
Breast cancer signatures for invasiveness and prognosis defined by deep sequencing of microRNA.
|
Proc Natl Acad Sci U S A
|
2012
|
2.07
|
113
|
A program of microRNAs controls osteogenic lineage progression by targeting transcription factor Runx2.
|
Proc Natl Acad Sci U S A
|
2011
|
2.05
|
114
|
Modulation of mismatch repair and genomic stability by miR-155.
|
Proc Natl Acad Sci U S A
|
2010
|
2.05
|
115
|
microRNAs: Master regulators as potential therapeutics in cancer.
|
Annu Rev Pharmacol Toxicol
|
2011
|
2.02
|
116
|
The E3 ubiquitin ligase Itch controls the protein stability of p63.
|
Proc Natl Acad Sci U S A
|
2006
|
2.01
|
117
|
MicroRNAs in human cancer: from research to therapy.
|
J Cell Sci
|
2007
|
2.00
|
118
|
MicroRNA involvement in hepatocellular carcinoma.
|
J Cell Mol Med
|
2008
|
1.99
|
119
|
MicroRNA-21 induces resistance to 5-fluorouracil by down-regulating human DNA MutS homolog 2 (hMSH2).
|
Proc Natl Acad Sci U S A
|
2010
|
1.99
|
120
|
miRNA profiling of cancer.
|
Curr Opin Genet Dev
|
2013
|
1.99
|
121
|
Overexpression of the HMGA2 gene in transgenic mice leads to the onset of pituitary adenomas.
|
Oncogene
|
2002
|
1.99
|
122
|
Mutator activity induced by microRNA-155 (miR-155) links inflammation and cancer.
|
Proc Natl Acad Sci U S A
|
2011
|
1.96
|
123
|
Chronic lymphocytic leukemia modeled in mouse by targeted miR-29 expression.
|
Proc Natl Acad Sci U S A
|
2010
|
1.94
|
124
|
MicroRNA cluster 221-222 and estrogen receptor alpha interactions in breast cancer.
|
J Natl Cancer Inst
|
2010
|
1.94
|
125
|
Characterization of the TCL-1 transgenic mouse as a preclinical drug development tool for human chronic lymphocytic leukemia.
|
Blood
|
2006
|
1.92
|
126
|
WW domain-containing proteins, WWOX and YAP, compete for interaction with ErbB-4 and modulate its transcriptional function.
|
Cancer Res
|
2005
|
1.91
|
127
|
Functional association between Wwox tumor suppressor protein and p73, a p53 homolog.
|
Proc Natl Acad Sci U S A
|
2004
|
1.91
|
128
|
MicroRNA genes are frequently located near mouse cancer susceptibility loci.
|
Proc Natl Acad Sci U S A
|
2007
|
1.90
|
129
|
Roles of small RNAs in tumor formation.
|
Trends Mol Med
|
2010
|
1.89
|
130
|
NOTCH1 mutations in CLL associated with trisomy 12.
|
Blood
|
2011
|
1.88
|
131
|
Expression and functional role of a transcribed noncoding RNA with an ultraconserved element in hepatocellular carcinoma.
|
Proc Natl Acad Sci U S A
|
2010
|
1.87
|
132
|
Epstein-Barr virus-induced miR-155 attenuates NF-kappaB signaling and stabilizes latent virus persistence.
|
J Virol
|
2008
|
1.86
|
133
|
Expression of microRNAs and protein-coding genes associated with perineural invasion in prostate cancer.
|
Prostate
|
2008
|
1.86
|
134
|
A methodology for the combined in situ analyses of the precursor and mature forms of microRNAs and correlation with their putative targets.
|
Nat Protoc
|
2009
|
1.85
|
135
|
Concern
WWOX gene restoration prevents lung cancer growth in vitro and in vivo.
|
Proc Natl Acad Sci U S A
|
2005
|
1.84
|
136
|
MiR-34a/c-Dependent PDGFR-α/β Downregulation Inhibits Tumorigenesis and Enhances TRAIL-Induced Apoptosis in Lung Cancer.
|
PLoS One
|
2013
|
1.82
|
137
|
Epigenetically deregulated microRNA-375 is involved in a positive feedback loop with estrogen receptor alpha in breast cancer cells.
|
Cancer Res
|
2010
|
1.82
|
138
|
13q14 deletions in CLL involve cooperating tumor suppressors.
|
Blood
|
2010
|
1.79
|
139
|
Physical and functional interactions between the Wwox tumor suppressor protein and the AP-2gamma transcription factor.
|
Cancer Res
|
2004
|
1.74
|
140
|
Chromosomal rearrangements and microRNAs: a new cancer link with clinical implications.
|
J Clin Invest
|
2007
|
1.72
|
141
|
PP2A-activating drugs selectively eradicate TKI-resistant chronic myeloid leukemic stem cells.
|
J Clin Invest
|
2013
|
1.72
|
142
|
Alterations of the tumor suppressor gene ARLTS1 in ovarian cancer.
|
Cancer Res
|
2006
|
1.71
|
143
|
Karyotype-specific microRNA signature in chronic lymphocytic leukemia.
|
Blood
|
2009
|
1.70
|
144
|
Association of inflammation-related and microRNA gene expression with cancer-specific mortality of colon adenocarcinoma.
|
Clin Cancer Res
|
2009
|
1.67
|
145
|
The WWOX tumor suppressor is essential for postnatal survival and normal bone metabolism.
|
J Biol Chem
|
2008
|
1.67
|
146
|
WWOX in biological control and tumorigenesis.
|
J Cell Physiol
|
2007
|
1.66
|
147
|
MicroRNAs as therapeutic targets in cancer.
|
Transl Res
|
2011
|
1.64
|
148
|
Lack of the architectural factor HMGA1 causes insulin resistance and diabetes in humans and mice.
|
Nat Med
|
2005
|
1.64
|
149
|
Genetic alterations of the tumor suppressor gene WWOX in esophageal squamous cell carcinoma.
|
Cancer Res
|
2002
|
1.62
|
150
|
Tcl1 functions as a transcriptional regulator and is directly involved in the pathogenesis of CLL.
|
Proc Natl Acad Sci U S A
|
2008
|
1.62
|
151
|
Akt phosphorylates and regulates Pdcd4 tumor suppressor protein.
|
Cancer Res
|
2005
|
1.61
|
152
|
E(mu)-TCL1 mice represent a model for immunotherapeutic reversal of chronic lymphocytic leukemia-induced T-cell dysfunction.
|
Proc Natl Acad Sci U S A
|
2009
|
1.61
|
153
|
At least ten genes define the imprinted Dlk1-Dio3 cluster on mouse chromosome 12qF1.
|
PLoS One
|
2009
|
1.60
|
154
|
MicroRNAs play a central role in molecular dysfunctions linking inflammation with cancer.
|
Immunol Rev
|
2013
|
1.60
|
155
|
The down-regulation of miR-125b in chronic lymphocytic leukemias leads to metabolic adaptation of cells to a transformed state.
|
Blood
|
2012
|
1.60
|
156
|
MicroRNAs, the immune system and rheumatic disease.
|
Nat Clin Pract Rheumatol
|
2008
|
1.55
|
157
|
Loss of WWOX expression in gastric carcinoma.
|
Clin Cancer Res
|
2004
|
1.55
|
158
|
B cell receptors in TCL1 transgenic mice resemble those of aggressive, treatment-resistant human chronic lymphocytic leukemia.
|
Proc Natl Acad Sci U S A
|
2006
|
1.55
|
159
|
Prognostic microRNA/mRNA signature from the integrated analysis of patients with invasive breast cancer.
|
Proc Natl Acad Sci U S A
|
2013
|
1.54
|
160
|
Transgenic mice overexpressing the wild-type form of the HMGA1 gene develop mixed growth hormone/prolactin cell pituitary adenomas and natural killer cell lymphomas.
|
Oncogene
|
2005
|
1.53
|
161
|
Resveratrol decreases the levels of miR-155 by upregulating miR-663, a microRNA targeting JunB and JunD.
|
Carcinogenesis
|
2010
|
1.52
|
162
|
MiR-494 is regulated by ERK1/2 and modulates TRAIL-induced apoptosis in non-small-cell lung cancer through BIM down-regulation.
|
Proc Natl Acad Sci U S A
|
2012
|
1.52
|
163
|
miR-221 silencing blocks hepatocellular carcinoma and promotes survival.
|
Cancer Res
|
2011
|
1.51
|
164
|
Causes and consequences of microRNA dysregulation.
|
Cancer J
|
2012
|
1.51
|
165
|
miR-155 regulates IFN-γ production in natural killer cells.
|
Blood
|
2012
|
1.47
|
166
|
Is miR-29 an oncogene or tumor suppressor in CLL?
|
Oncotarget
|
2010
|
1.46
|
167
|
A role for the WWOX gene in prostate cancer.
|
Cancer Res
|
2006
|
1.45
|
168
|
The tumor suppressor gene WWOX at FRA16D is involved in pancreatic carcinogenesis.
|
Clin Cancer Res
|
2004
|
1.45
|
169
|
A microRNA signature defines chemoresistance in ovarian cancer through modulation of angiogenesis.
|
Proc Natl Acad Sci U S A
|
2013
|
1.44
|
170
|
miR-181b is a biomarker of disease progression in chronic lymphocytic leukemia.
|
Blood
|
2011
|
1.44
|
171
|
Integrated microRNA and mRNA signatures associated with survival in triple negative breast cancer.
|
PLoS One
|
2013
|
1.43
|
172
|
MicroRNA profiling as a tool to understand prognosis, therapy response and resistance in breast cancer.
|
Eur J Cancer
|
2008
|
1.42
|
173
|
WW domain containing oxidoreductase gene expression is altered in non-small cell lung cancer.
|
Cancer Res
|
2003
|
1.42
|
174
|
Interplay between microRNAs and the epigenetic machinery: an intricate network.
|
Biochim Biophys Acta
|
2010
|
1.41
|
175
|
miR-218 directs a Wnt signaling circuit to promote differentiation of osteoblasts and osteomimicry of metastatic cancer cells.
|
J Biol Chem
|
2012
|
1.39
|
176
|
Long-range interaction and correlation between MYC enhancer and oncogenic long noncoding RNA CARLo-5.
|
Proc Natl Acad Sci U S A
|
2014
|
1.39
|
177
|
MicroRNA-1 is a candidate tumor suppressor and prognostic marker in human prostate cancer.
|
Nucleic Acids Res
|
2011
|
1.39
|
178
|
Isoform-specific monoubiquitination, endocytosis, and degradation of alternatively spliced ErbB4 isoforms.
|
Proc Natl Acad Sci U S A
|
2008
|
1.39
|
179
|
Epigenetic changes during disease progression in a murine model of human chronic lymphocytic leukemia.
|
Proc Natl Acad Sci U S A
|
2009
|
1.39
|
180
|
Identification of differentially expressed microRNAs by microarray: a possible role for microRNA genes in pituitary adenomas.
|
J Cell Physiol
|
2007
|
1.37
|
181
|
Association of Wwox with ErbB4 in breast cancer.
|
Cancer Res
|
2007
|
1.37
|
182
|
Altered Runx1 subnuclear targeting enhances myeloid cell proliferation and blocks differentiation by activating a miR-24/MKP-7/MAPK network.
|
Cancer Res
|
2009
|
1.37
|
183
|
miR-29ab1 deficiency identifies a negative feedback loop controlling Th1 bias that is dysregulated in multiple sclerosis.
|
J Immunol
|
2012
|
1.35
|
184
|
Regulation of acute graft-versus-host disease by microRNA-155.
|
Blood
|
2012
|
1.35
|
185
|
Allele loss and promoter hypermethylation of VHL, RAR-beta, RASSF1A, and FHIT tumor suppressor genes on chromosome 3p in esophageal squamous cell carcinoma.
|
Cancer Res
|
2003
|
1.34
|
186
|
Haploinsufficiency of the Hmga1 gene causes cardiac hypertrophy and myelo-lymphoproliferative disorders in mice.
|
Cancer Res
|
2006
|
1.34
|
187
|
The role of microRNA and other non-coding RNA in the pathogenesis of chronic lymphocytic leukemia.
|
Best Pract Res Clin Haematol
|
2007
|
1.34
|
188
|
Retracted
Unique microRNA profile in end-stage heart failure indicates alterations in specific cardiovascular signaling networks.
|
J Biol Chem
|
2009
|
1.33
|
189
|
Chronic lymphocytic leukemia of Emu-TCL1 transgenic mice undergoes rapid cell turnover that can be offset by extrinsic CD257 to accelerate disease progression.
|
Blood
|
2009
|
1.32
|
190
|
Expression of FRA16D/WWOX and FRA3B/FHIT genes in hematopoietic malignancies.
|
Mol Cancer Res
|
2003
|
1.32
|
191
|
Insulin growth factor signaling is regulated by microRNA-486, an underexpressed microRNA in lung cancer.
|
Proc Natl Acad Sci U S A
|
2013
|
1.32
|
192
|
Relationships of microRNA expression in mouse lung with age and exposure to cigarette smoke and light.
|
FASEB J
|
2009
|
1.31
|
193
|
Comprehensive miRNA profiling of surgically staged endometrial cancer.
|
Am J Obstet Gynecol
|
2010
|
1.30
|
194
|
Aberrant regulation of pVHL levels by microRNA promotes the HIF/VEGF axis in CLL B cells.
|
Blood
|
2009
|
1.29
|
195
|
Resveratrol modulates the levels of microRNAs targeting genes encoding tumor-suppressors and effectors of TGFβ signaling pathway in SW480 cells.
|
Biochem Pharmacol
|
2010
|
1.28
|
196
|
microRNA expression profiling identifies a four microRNA signature as a novel diagnostic and prognostic biomarker in triple negative breast cancers.
|
Oncotarget
|
2014
|
1.28
|
197
|
Oncogenic All1 fusion proteins target Drosha-mediated microRNA processing.
|
Proc Natl Acad Sci U S A
|
2007
|
1.27
|
198
|
Restoration of fragile histidine triad (FHIT) expression induces apoptosis and suppresses tumorigenicity in lung and cervical cancer cell lines.
|
Proc Natl Acad Sci U S A
|
2002
|
1.27
|
199
|
Molecular basis of CLL.
|
Semin Cancer Biol
|
2010
|
1.26
|
200
|
Disrupted microRNA expression caused by Mecp2 loss in a mouse model of Rett syndrome.
|
Epigenetics
|
2010
|
1.26
|
201
|
Effect of rapamycin on mouse chronic lymphocytic leukemia and the development of nonhematopoietic malignancies in Emu-TCL1 transgenic mice.
|
Cancer Res
|
2006
|
1.26
|
202
|
Cross-talk between MET and EGFR in non-small cell lung cancer involves miR-27a and Sprouty2.
|
Proc Natl Acad Sci U S A
|
2013
|
1.24
|
203
|
Estrogen mediated-activation of miR-191/425 cluster modulates tumorigenicity of breast cancer cells depending on estrogen receptor status.
|
PLoS Genet
|
2013
|
1.24
|
204
|
Microvesicles containing miRNAs promote muscle cell death in cancer cachexia via TLR7.
|
Proc Natl Acad Sci U S A
|
2014
|
1.24
|
205
|
Liver tumorigenicity promoted by microRNA-221 in a mouse transgenic model.
|
Hepatology
|
2012
|
1.23
|
206
|
Non-codingRNA sequence variations in human chronic lymphocytic leukemia and colorectal cancer.
|
Carcinogenesis
|
2009
|
1.23
|
207
|
Protective role of miR-155 in breast cancer through RAD51 targeting impairs homologous recombination after irradiation.
|
Proc Natl Acad Sci U S A
|
2014
|
1.22
|
208
|
MicroRNA expression profiling of male breast cancer.
|
Breast Cancer Res
|
2009
|
1.22
|
209
|
Fhit interaction with ferredoxin reductase triggers generation of reactive oxygen species and apoptosis of cancer cells.
|
J Biol Chem
|
2008
|
1.22
|
210
|
Role of microRNAs in lymphoid biology and disease.
|
Curr Opin Hematol
|
2011
|
1.22
|
211
|
Physical association with WWOX suppresses c-Jun transcriptional activity.
|
Cancer Res
|
2006
|
1.21
|
212
|
Chronic lymphocytic leukemia: interplay between noncoding RNAs and protein-coding genes.
|
Blood
|
2009
|
1.21
|
213
|
Fhit tumor suppressor: guardian of the preneoplastic genome.
|
Future Oncol
|
2008
|
1.21
|
214
|
Negative regulation of BRCA1 gene expression by HMGA1 proteins accounts for the reduced BRCA1 protein levels in sporadic breast carcinoma.
|
Mol Cell Biol
|
2003
|
1.20
|
215
|
Animal models for chronic lymphocytic leukemia.
|
J Cell Biochem
|
2007
|
1.19
|
216
|
The Nedd4-binding partner 1 (N4BP1) protein is an inhibitor of the E3 ligase Itch.
|
Proc Natl Acad Sci U S A
|
2007
|
1.19
|
217
|
FHIT: from gene discovery to cancer treatment and prevention.
|
Lancet Oncol
|
2002
|
1.19
|
218
|
Targeted ablation of the WW domain-containing oxidoreductase tumor suppressor leads to impaired steroidogenesis.
|
Endocrinology
|
2008
|
1.19
|
219
|
Inactivation of the Wwox gene accelerates forestomach tumor progression in vivo.
|
Cancer Res
|
2007
|
1.19
|
220
|
Non-coding RNAs in cancer initiation and progression and as novel biomarkers.
|
Mol Oncol
|
2011
|
1.18
|
221
|
MicroRNAs/TP53 feedback circuitry in glioblastoma multiforme.
|
Proc Natl Acad Sci U S A
|
2012
|
1.18
|
222
|
Adenoviral transduction of TESTIN gene into breast and uterine cancer cell lines promotes apoptosis and tumor reduction in vivo.
|
Clin Cancer Res
|
2005
|
1.18
|
223
|
MicroRNAs: fundamental facts and involvement in human diseases.
|
Birth Defects Res C Embryo Today
|
2006
|
1.17
|
224
|
MicroRNA expression profiling in human Barrett's carcinogenesis.
|
Int J Cancer
|
2011
|
1.17
|
225
|
MicroRNA-31 predicts the presence of lymph node metastases and survival in patients with lung adenocarcinoma.
|
Clin Cancer Res
|
2013
|
1.17
|
226
|
Dysregulation of miR-31 and miR-21 induced by zinc deficiency promotes esophageal cancer.
|
Carcinogenesis
|
2012
|
1.16
|
227
|
Functional implications of microRNAs in acute myeloid leukemia by integrating microRNA and messenger RNA expression profiling.
|
Cancer
|
2011
|
1.16
|
228
|
MicroRNA profiling for the identification of cancers with unknown primary tissue-of-origin.
|
J Pathol
|
2011
|
1.15
|
229
|
Designed FHIT alleles establish that Fhit-induced apoptosis in cancer cells is limited by substrate binding.
|
Proc Natl Acad Sci U S A
|
2003
|
1.14
|
230
|
Chemoprevention of cigarette smoke-induced alterations of MicroRNA expression in rat lungs.
|
Cancer Prev Res (Phila)
|
2010
|
1.13
|
231
|
Fez1/Lzts1 absence impairs Cdk1/Cdc25C interaction during mitosis and predisposes mice to cancer development.
|
Cancer Cell
|
2007
|
1.13
|
232
|
In vivo NCL targeting affects breast cancer aggressiveness through miRNA regulation.
|
J Exp Med
|
2013
|
1.13
|
233
|
FHIT as tumor suppressor: mechanisms and therapeutic opportunities.
|
Cancer Biol Ther
|
2002
|
1.11
|
234
|
MicroRNAs in the ontogeny of leukemias and lymphomas.
|
Leuk Lymphoma
|
2009
|
1.11
|
235
|
The novel deacetylase inhibitor AR-42 demonstrates pre-clinical activity in B-cell malignancies in vitro and in vivo.
|
PLoS One
|
2010
|
1.11
|
236
|
MicroRNAs as therapeutic targets in chemoresistance.
|
Drug Resist Updat
|
2013
|
1.11
|
237
|
Regulation of BRCA1 transcription by specific single-stranded DNA binding factors.
|
Mol Cell Biol
|
2003
|
1.10
|
238
|
Fhit is a physiological target of the protein kinase Src.
|
Proc Natl Acad Sci U S A
|
2004
|
1.10
|
239
|
Fragile site orthologs FHIT/FRA3B and Fhit/Fra14A2: evolutionarily conserved but highly recombinogenic.
|
Proc Natl Acad Sci U S A
|
2003
|
1.09
|
240
|
Micro-RNAs in gastrointestinal and liver disease.
|
Gastroenterology
|
2008
|
1.09
|
241
|
Mutated beta-catenin evades a microRNA-dependent regulatory loop.
|
Proc Natl Acad Sci U S A
|
2011
|
1.08
|
242
|
The Role of microRNAs in the Tumorigenesis of Ovarian Cancer.
|
Front Oncol
|
2013
|
1.08
|
243
|
Oncosuppressive role of p53-induced miR-205 in triple negative breast cancer.
|
Mol Oncol
|
2012
|
1.07
|
244
|
Contact inhibition modulates intracellular levels of miR-223 in a p27kip1-dependent manner.
|
Oncotarget
|
2014
|
1.07
|
245
|
WW-domain-containing oxidoreductase is associated with low plasma HDL-C levels.
|
Am J Hum Genet
|
2008
|
1.06
|
246
|
microRNA involvement in hepatocellular carcinoma.
|
Anticancer Agents Med Chem
|
2011
|
1.06
|
247
|
B-cell malignancies in microRNA Eμ-miR-17~92 transgenic mice.
|
Proc Natl Acad Sci U S A
|
2013
|
1.06
|
248
|
Characterization of a new chronic lymphocytic leukemia cell line for mechanistic in vitro and in vivo studies relevant to disease.
|
PLoS One
|
2013
|
1.06
|
249
|
Regression of upper gastric cancer in mice by FHIT gene delivery.
|
FASEB J
|
2003
|
1.06
|
250
|
MicroRNA-375 and MicroRNA-221: Potential Noncoding RNAs Associated with Antiproliferative Activity of Benzyl Isothiocyanate in Pancreatic Cancer.
|
Genes Cancer
|
2011
|
1.06
|
251
|
ROR1 can interact with TCL1 and enhance leukemogenesis in Eμ-TCL1 transgenic mice.
|
Proc Natl Acad Sci U S A
|
2013
|
1.05
|
252
|
miR-155 targets histone deacetylase 4 (HDAC4) and impairs transcriptional activity of B-cell lymphoma 6 (BCL6) in the Eμ-miR-155 transgenic mouse model.
|
Proc Natl Acad Sci U S A
|
2012
|
1.05
|
253
|
IRF4 mutations in chronic lymphocytic leukemia.
|
Blood
|
2011
|
1.05
|
254
|
Collecting duct carcinoma of the kidney: an immunohistochemical study of 11 cases.
|
BMC Urol
|
2004
|
1.05
|
255
|
Reduced FEZ1/LZTS1 expression and outcome prediction in lung cancer.
|
Cancer Res
|
2005
|
1.04
|
256
|
Tcl1 protein functions as an inhibitor of de novo DNA methylation in B-cell chronic lymphocytic leukemia (CLL).
|
Proc Natl Acad Sci U S A
|
2012
|
1.04
|
257
|
Intramitochondrial calcium regulation by the FHIT gene product sensitizes to apoptosis.
|
Proc Natl Acad Sci U S A
|
2009
|
1.04
|
258
|
Knockout mice reveal a tumor suppressor function for Testin.
|
Proc Natl Acad Sci U S A
|
2005
|
1.04
|
259
|
FEZ1/LZTS1 is down-regulated in high-grade bladder cancer, and its restoration suppresses tumorigenicity in transitional cell carcinoma cells.
|
Am J Pathol
|
2002
|
1.03
|
260
|
Fragile gene product, Fhit, in oxidative and replicative stress responses.
|
Cancer Sci
|
2009
|
1.03
|
261
|
miR-29 acts as a decoy in sarcomas to protect the tumor suppressor A20 mRNA from degradation by HuR.
|
Sci Signal
|
2013
|
1.02
|
262
|
Loss of Hmga1 gene function affects embryonic stem cell lympho-hematopoietic differentiation.
|
FASEB J
|
2003
|
1.02
|
263
|
Biological functions of mammalian Nit1, the counterpart of the invertebrate NitFhit Rosetta stone protein, a possible tumor suppressor.
|
J Biol Chem
|
2006
|
1.02
|
264
|
Selected microRNAs define cell fate determination of murine central memory CD8 T cells.
|
PLoS One
|
2010
|
1.02
|
265
|
Zinc replenishment reverses overexpression of the proinflammatory mediator S100A8 and esophageal preneoplasia in the rat.
|
Gastroenterology
|
2008
|
1.02
|
266
|
Transcription signatures encoded by ultraconserved genomic regions in human prostate cancer.
|
Mol Cancer
|
2013
|
1.01
|
267
|
Overexpression of TCL1 activates the endoplasmic reticulum stress response: a novel mechanism of leukemic progression in mice.
|
Blood
|
2012
|
1.00
|
268
|
Identification of a risk dependent microRNA expression signature in myelodysplastic syndromes.
|
Br J Haematol
|
2011
|
1.00
|
269
|
Correlation of fragile histidine triad (Fhit) protein structural features with effector interactions and biological functions.
|
J Biol Chem
|
2008
|
1.00
|
270
|
Restoration of receptor-type protein tyrosine phosphatase eta function inhibits human pancreatic carcinoma cell growth in vitro and in vivo.
|
Carcinogenesis
|
2004
|
1.00
|
271
|
Down-regulation of homeobox genes MEIS1 and HOXA in MLL-rearranged acute leukemia impairs engraftment and reduces proliferation.
|
Proc Natl Acad Sci U S A
|
2011
|
1.00
|
272
|
p53 deficiency accelerates induction and progression of esophageal and forestomach tumors in zinc-deficient mice.
|
Cancer Res
|
2003
|
0.99
|
273
|
MicroRNA regulation of tumorigenesis, cancer progression and interpatient heterogeneity: towards clinical use.
|
Genome Biol
|
2014
|
0.99
|
274
|
Allelic loss on chromosome 3p21.3 and promoter hypermethylation of semaphorin 3B in non-small cell lung cancer.
|
Cancer Res
|
2003
|
0.99
|
275
|
Genetic ablation of Ptprj, a mouse cancer susceptibility gene, results in normal growth and development and does not predispose to spontaneous tumorigenesis.
|
DNA Cell Biol
|
2006
|
0.99
|
276
|
Restoration of fragile histidine triad (FHIT) expression induces apoptosis and suppresses tumorigenicity in breast cancer cell lines.
|
Cancer Res
|
2003
|
0.98
|
277
|
Overexpression of miR-155 causes expansion, arrest in terminal differentiation and functional activation of mouse natural killer cells.
|
Blood
|
2013
|
0.98
|
278
|
Suppression of microRNA-9 by mutant EGFR signaling upregulates FOXP1 to enhance glioblastoma tumorigenicity.
|
Cancer Res
|
2014
|
0.98
|
279
|
MicroRNA in cancer: new hopes for antineoplastic chemotherapy.
|
Ups J Med Sci
|
2012
|
0.98
|
280
|
ALL1 fusion proteins induce deregulation of EphA7 and ERK phosphorylation in human acute leukemias.
|
Proc Natl Acad Sci U S A
|
2007
|
0.97
|
281
|
Autoantigen can promote progression to a more aggressive TCL1 leukemia by selecting variants with enhanced B-cell receptor signaling.
|
Proc Natl Acad Sci U S A
|
2013
|
0.97
|
282
|
Tcl1 interacts with Atm and enhances NF-κB activation in hematologic malignancies.
|
Blood
|
2011
|
0.96
|
283
|
Inflammation regulates microRNA expression in cooperation with p53 and nitric oxide.
|
Int J Cancer
|
2011
|
0.96
|
284
|
A new role for microRNAs, as ligands of Toll-like receptors.
|
RNA Biol
|
2013
|
0.96
|
285
|
The BCSC-1 locus at chromosome 11q23-q24 is a candidate tumor suppressor gene.
|
Proc Natl Acad Sci U S A
|
2003
|
0.95
|
286
|
Identification of microRNA activity by Targets' Reverse EXpression.
|
Bioinformatics
|
2009
|
0.95
|
287
|
MiR-181b: new perspective to evaluate disease progression in chronic lymphocytic leukemia.
|
Oncotarget
|
2012
|
0.95
|
288
|
Retracted
POZ-, AT-hook-, and zinc finger-containing protein (PATZ) interacts with human oncogene B cell lymphoma 6 (BCL6) and is required for its negative autoregulation.
|
J Biol Chem
|
2012
|
0.95
|
289
|
Pathogenetic and clinical relevance of microRNAs in colorectal cancer.
|
Cancer Genomics Proteomics
|
2009
|
0.95
|
290
|
A differential microRNA profile distinguishes cholangiocarcinoma from pancreatic adenocarcinoma.
|
Ann Surg Oncol
|
2013
|
0.93
|
291
|
Lung cancer susceptibility in Fhit-deficient mice is increased by Vhl haploinsufficiency.
|
Cancer Res
|
2005
|
0.93
|
292
|
Zinc deficiency activates S100A8 inflammation in the absence of COX-2 and promotes murine oral-esophageal tumor progression.
|
Int J Cancer
|
2010
|
0.93
|
293
|
Retracted
Targeted disruption of the murine homeodomain-interacting protein kinase-2 causes growth deficiency in vivo and cell cycle arrest in vitro.
|
DNA Cell Biol
|
2009
|
0.93
|
294
|
Apoptomirs: small molecules have gained the license to kill.
|
Endocr Relat Cancer
|
2010
|
0.93
|
295
|
A mouse model of the fragile gene FHIT: From carcinogenesis to gene therapy and cancer prevention.
|
Mutat Res
|
2005
|
0.93
|
296
|
Therapy of human pancreatic carcinoma based on suppression of HMGA1 protein synthesis in preclinical models.
|
Cancer Gene Ther
|
2004
|
0.92
|
297
|
Cleavage of the transactivation-inhibitory domain of p63 by caspases enhances apoptosis.
|
Proc Natl Acad Sci U S A
|
2007
|
0.92
|
298
|
MicroRNAs and lung cancer: from markers to targets.
|
Cell Cycle
|
2011
|
0.92
|
299
|
Frag1, a homolog of alternative replication factor C subunits, links replication stress surveillance with apoptosis.
|
Proc Natl Acad Sci U S A
|
2005
|
0.92
|
300
|
Hypoxia induces the overexpression of microRNA-21 in pancreatic cancer cells.
|
J Surg Res
|
2013
|
0.92
|
301
|
Toll-like receptor 3 (TLR3) activation induces microRNA-dependent reexpression of functional RARβ and tumor regression.
|
Proc Natl Acad Sci U S A
|
2013
|
0.92
|
302
|
Mechanism of human Hb switching: a possible role of the kit receptor/miR 221-222 complex.
|
Haematologica
|
2010
|
0.91
|
303
|
MicroRNAs in the pathogeny of chronic lymphocytic leukaemia.
|
Br J Haematol
|
2007
|
0.91
|
304
|
Modulation of gene expression in precancerous rat esophagus by dietary zinc deficit and replenishment.
|
Cancer Res
|
2005
|
0.91
|
305
|
MicroRNA expression profiling in acute myeloid and chronic lymphocytic leukaemias.
|
Best Pract Res Clin Haematol
|
2009
|
0.91
|
306
|
GAM/ZFp/ZNF512B is central to a gene sensor circuitry involving cell-cycle regulators, TGF{beta} effectors, Drosha and microRNAs with opposite oncogenic potentials.
|
Nucleic Acids Res
|
2010
|
0.91
|
307
|
BRCA1 5083del19 mutant allele selectively up-regulates periostin expression in vitro and in vivo.
|
Clin Cancer Res
|
2008
|
0.91
|
308
|
Zinc supplementation suppresses 4-nitroquinoline 1-oxide-induced rat oral carcinogenesis.
|
Carcinogenesis
|
2011
|
0.91
|
309
|
Akt regulates drug-induced cell death through Bcl-w downregulation.
|
PLoS One
|
2008
|
0.91
|
310
|
Fez1/Lzts1-deficient mice are more susceptible to N-butyl-N-(4-hydroxybutil) nitrosamine (BBN) carcinogenesis.
|
Carcinogenesis
|
2008
|
0.90
|
311
|
MicroRNAs in mouse models of lymphoid malignancies.
|
J Nucleic Acids Investig
|
2010
|
0.90
|
312
|
Micro-RNA Expression and Function in Lymphomas.
|
Adv Hematol
|
2011
|
0.90
|
313
|
MicroRNAs in diagnosis and prognosis in cancer: what does the future hold?
|
Pharmacogenomics
|
2010
|
0.89
|
314
|
Fhit modulates the DNA damage checkpoint response.
|
Cancer Res
|
2006
|
0.89
|
315
|
Promoter hypermethylation of RASSF1A in esophageal squamous cell carcinoma.
|
Clin Cancer Res
|
2003
|
0.89
|
316
|
MicroRNA dysregulation in cancer: opportunities for the development of microRNA-based drugs.
|
IDrugs
|
2010
|
0.89
|
317
|
miR-EdiTar: a database of predicted A-to-I edited miRNA target sites.
|
Bioinformatics
|
2012
|
0.89
|
318
|
MicroRNAs in cancer: personalizing diagnosis and therapy.
|
Ann N Y Acad Sci
|
2010
|
0.88
|
319
|
Genome wide identification of recessive cancer genes by combinatorial mutation analysis.
|
PLoS One
|
2008
|
0.88
|
320
|
Tal1 transgenic expression reveals absence of B lymphocytes.
|
Cancer Res
|
2006
|
0.88
|
321
|
TNF-alpha signal transduction in rat neonatal cardiac myocytes: definition of pathways generating from the TNF-alpha receptor.
|
FASEB J
|
2002
|
0.88
|
322
|
Isolation and characterization of a novel gene, hRFI, preferentially expressed in esophageal cancer.
|
Oncogene
|
2002
|
0.88
|
323
|
HMGA1 protein expression sensitizes cells to cisplatin-induced cell death.
|
Oncogene
|
2005
|
0.87
|
324
|
Tumor suppressor functions of ARLTS1 in lung cancers.
|
Cancer Res
|
2007
|
0.87
|
325
|
Synthetic microRNA cassette dosing: pharmacokinetics, tissue distribution and bioactivity.
|
Mol Pharm
|
2012
|
0.87
|
326
|
The High Mobility Group A2 gene is amplified and overexpressed in human prolactinomas.
|
Cancer Res
|
2002
|
0.87
|
327
|
Phosphorylation of the human Fhit tumor suppressor on tyrosine 114 in Escherichia coli and unexpected steady state kinetics of the phosphorylated forms.
|
Biochemistry
|
2005
|
0.87
|
328
|
Transcription factor-mediated epigenetic regulation of cell growth and phenotype for biological control and cancer.
|
Adv Enzyme Regul
|
2009
|
0.87
|
329
|
Implications of the miR-10 family in chemotherapy response of NPM1-mutated AML.
|
Blood
|
2014
|
0.87
|
330
|
DLX genes as targets of ALL-1: DLX 2,3,4 down-regulation in t(4;11) acute lymphoblastic leukemias.
|
J Leukoc Biol
|
2003
|
0.86
|
331
|
Surface expression of Bcl-2 in chronic lymphocytic leukemia and other B-cell leukemias and lymphomas without a breakpoint t(14;18).
|
Mol Med
|
2008
|
0.86
|
332
|
miRNAs in precancerous lesions of the gastrointestinal tract.
|
World J Gastroenterol
|
2011
|
0.86
|
333
|
AP-1 elements and TCL1 protein regulate expression of the gene encoding protein tyrosine phosphatase PTPROt in leukemia.
|
Blood
|
2011
|
0.86
|
334
|
Influence of FHIT on benzo[a]pyrene-induced tumors and alopecia in mice: chemoprevention by budesonide and N-acetylcysteine.
|
Proc Natl Acad Sci U S A
|
2006
|
0.86
|
335
|
The self-assembly of anticancer camptothecin-dipeptide nanotubes: a minimalistic and high drug loading approach to increased efficacy.
|
Chemistry
|
2014
|
0.85
|
336
|
Early loss of Fhit in the respiratory tract of rodents exposed to environmental cigarette smoke.
|
Cancer Res
|
2006
|
0.85
|
337
|
A Sleeping Beauty screen reveals NF-kB activation in CLL mouse model.
|
Blood
|
2013
|
0.85
|
338
|
Molecular and cytogenetical alterations induced by environmental cigarette smoke in mice heterozygous for Fhit.
|
Cancer Res
|
2007
|
0.84
|
339
|
Take your "M" time.
|
Cell Cycle
|
2007
|
0.84
|
340
|
Fhit delocalizes annexin a4 from plasma membrane to cytosol and sensitizes lung cancer cells to paclitaxel.
|
PLoS One
|
2013
|
0.84
|
341
|
Novel insights in molecular mechanisms of CLL.
|
Curr Pharm Des
|
2012
|
0.83
|
342
|
Role of PTPRJ genotype in papillary thyroid carcinoma risk.
|
Endocr Relat Cancer
|
2010
|
0.83
|
343
|
Discovery of PTPRJ agonist peptides that effectively inhibit in vitro cancer cell proliferation and tube formation.
|
ACS Chem Biol
|
2013
|
0.83
|
344
|
Isolation and functional characterization of peptide agonists of PTPRJ, a tyrosine phosphatase receptor endowed with tumor suppressor activity.
|
ACS Chem Biol
|
2012
|
0.83
|
345
|
A novel ultrasensitive hybridization-based ELISA method for 2-methoxyphosphorothiolate microRNAs and its in vitro and in vivo application.
|
AAPS J
|
2010
|
0.83
|
346
|
Tcl1 as a model for lymphomagenesis.
|
Hematol Oncol Clin North Am
|
2004
|
0.83
|
347
|
MicroRNA in chronic lymphocytic leukemia: transitioning from laboratory-based investigation to clinical application.
|
Cancer Genet Cytogenet
|
2010
|
0.82
|
348
|
MicroRNA Expression Profiling in the Histological Subtypes of Barrett's Metaplasia.
|
Clin Transl Gastroenterol
|
2013
|
0.82
|
349
|
Cancer prevention and therapy in a preclinical mouse model: impact of FHIT viruses.
|
Curr Gene Ther
|
2004
|
0.81
|
350
|
Coordinate loss of fragile gene expression in pancreatobiliary cancers: correlations among markers and clinical features.
|
Ann Surg Oncol
|
2009
|
0.81
|
351
|
Fez1/Lzts1 a new mitotic regulator implicated in cancer development.
|
Cell Div
|
2007
|
0.81
|
352
|
MicroRNAs and cancer: introduction.
|
Semin Oncol
|
2011
|
0.81
|
353
|
MicroRNA dysregulation in acute myeloid leukemia.
|
J Clin Oncol
|
2013
|
0.81
|
354
|
Akt phosphorylates Tal1 oncoprotein and inhibits its repressor activity.
|
Cancer Res
|
2005
|
0.81
|
355
|
Effect of zinc supplementation on N-nitrosomethylbenzylamine-induced forestomach tumor development and progression in tumor suppressor-deficient mouse strains.
|
Carcinogenesis
|
2010
|
0.81
|
356
|
Correction: MiR-34a/c-Dependent PDGFR-α/β Downregulation Inhibits Tumorigenesis and Enhances TRAIL-Induced Apoptosis in Lung Cancer.
|
PLoS One
|
2015
|
0.80
|
357
|
Preclinical assessment of FHIT gene replacement therapy in human leukemia using a chimeric adenovirus, Ad5/F35.
|
Clin Cancer Res
|
2006
|
0.80
|
358
|
MicroRNA profiling in ovarian cancer.
|
Methods Mol Biol
|
2013
|
0.80
|
359
|
Inactivation of the FHIT gene favors bladder cancer development.
|
Clin Cancer Res
|
2004
|
0.80
|
360
|
LZTS1 downregulation confers paclitaxel resistance and is associated with worse prognosis in breast cancer.
|
Oncotarget
|
2014
|
0.80
|
361
|
"ApoptomiRs" in vascular cells: their role in physiological and pathological angiogenesis.
|
Vascul Pharmacol
|
2011
|
0.80
|
362
|
Differentially expressed genes execute zinc-induced apoptosis in precancerous esophageal epithelium of zinc-deficient rats.
|
Oncogene
|
2004
|
0.80
|
363
|
miR deregulation in CLL.
|
Adv Exp Med Biol
|
2013
|
0.79
|
364
|
NCCN task force report: molecular markers in leukemias and lymphomas.
|
J Natl Compr Canc Netw
|
2009
|
0.79
|
365
|
MicroRNA-29b mediates altered innate immune development in acute leukemia.
|
J Clin Invest
|
2016
|
0.78
|
366
|
Retracted
Expression of a truncated Hmga1b gene induces gigantism, lipomatosis and B-cell lymphomas in mice.
|
Eur J Cancer
|
2010
|
0.78
|
367
|
microRNA-mediated survivin control of pluripotency.
|
J Cell Physiol
|
2015
|
0.78
|
368
|
Prevention of urinary bladder cancer in the FHIT knock-out mouse with Rofecoxib, a Cox-2 inhibitor.
|
Urol Oncol
|
2009
|
0.78
|
369
|
Extracellular circulating viral microRNAs: current knowledge and perspectives.
|
Front Genet
|
2013
|
0.78
|
370
|
Pleiotropic antitumor effects of the pan-HDAC inhibitor ITF2357 against c-Myc-overexpressing human B-cell non-Hodgkin lymphomas.
|
Int J Cancer
|
2014
|
0.78
|
371
|
Compatible solutes from hyperthermophiles improve the quality of DNA microarrays.
|
BMC Biotechnol
|
2007
|
0.78
|
372
|
Targeting mature T cell leukemia: new understanding of molecular pathways.
|
Am J Pharmacogenomics
|
2003
|
0.78
|
373
|
Functional assays for specific targeting and delivery of RNA nanoparticles to brain tumor.
|
Methods Mol Biol
|
2015
|
0.77
|
374
|
LINCing chromatin remodeling to metastasis.
|
Nat Biotechnol
|
2010
|
0.77
|
375
|
MicroRNA dysregulation in cancer: diagnostics, monitoring and therapeutics. A comprehensive review.
|
EMBO Mol Med
|
2017
|
0.76
|
376
|
The long journey of TCL1 transgenic mice: lessons learned in the last 15 years.
|
Gene Expr
|
2015
|
0.76
|
377
|
Purification and biochemical properties of the Drosophila TAC1 complex.
|
Methods Enzymol
|
2004
|
0.76
|
378
|
Heat shock protein 70 regulates Tcl1 expression in leukemia and lymphomas.
|
Blood
|
2012
|
0.76
|
379
|
Downregulation of p53-inducible microRNAs 192, 194, and 215 Impairs the p53/MDM2 Autoregulatory Loop in Multiple Myeloma Development.
|
Cancer Cell
|
2016
|
0.76
|
380
|
Chronic lymphocytic leukaemia.
|
Nat Rev Dis Prim
|
2017
|
0.76
|
381
|
Self-assembly of a 5-fluorouracil-dipeptide hydrogel.
|
Chem Commun (Camb)
|
2016
|
0.76
|
382
|
Hmga1 null mice are less susceptible to chemically induced skin carcinogenesis.
|
Eur J Cancer
|
2007
|
0.75
|
383
|
Correction: In vivo NCL targeting affects breast cancer aggressiveness through miRNA regulation.
|
J Exp Med
|
2017
|
0.75
|
384
|
Retraction: Are circRNAs involved in cancer pathogenesis?
|
Nat Rev Clin Oncol
|
2016
|
0.75
|
385
|
Preface.
|
Adv Cancer Res
|
2017
|
0.75
|
386
|
Genetic and Epigenetic Silencing of MicroRNA-203 Enhances ABL1 and BCR-ABL1 Oncogene Expression.
|
Cancer Cell
|
2016
|
0.75
|
387
|
POZ-, AT-hook-, and zinc finger-containing protein (PATZ) interacts with the human oncogene B cell lymphoma 6 (BCL6) and is required for its negative autoregulation.
|
J Biol Chem
|
2017
|
0.75
|
388
|
Fhit interaction with ferredoxin reductase triggers generation of reactive oxygen species and apoptosis of cancer cells.
|
J Biol Chem
|
2017
|
0.75
|
389
|
A unique microRNA profile in end-stage heart failure indicates alterations in specific cardiovascular signaling networks.
|
J Biol Chem
|
2016
|
0.75
|
390
|
BRCA1 IVS2-2delA: a deleterious mutation in a family of Asian descent.
|
Cancer Genet Cytogenet
|
2004
|
0.75
|
391
|
Foreword.
|
Adv Exp Med Biol
|
2015
|
0.75
|