Reversine, a 2,6-disubstituted purine, as an anti-cancer agent in differentiated and undifferentiated thyroid cancer cells.

PubWeight™: 0.87‹?›

🔗 View Article (PMID 22477067)

Published in Pharm Res on April 04, 2012

Authors

Shih-Che Hua1, Tien-Chun Chang, Hau-Ren Chen, Chieh-Hsiang Lu, Yi-Wen Liu, Shu-Hsin Chen, Hui-I Yu, Yi-Ping Chang, Ying-Ray Lee

Author Affiliations

1: Division of Endocrinology & Metabolism, Department of Internal Medicine, Chiayi Christian Hospital, Chiayi, Taiwan.

Articles by these authors

A genome-wide association study identifies susceptibility variants for type 2 diabetes in Han Chinese. PLoS Genet (2010) 3.25

A prospective, multicentre study to investigate the efficacy, safety and tolerability of octreotide LAR (long-acting repeatable octreotide) in the primary therapy of patients with acromegaly. Clin Endocrinol (Oxf) (2007) 2.01

Functional and physical interactions between components of the Prp19p-associated complex. Nucleic Acids Res (2002) 1.59

Lovastatin, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, induces apoptosis and differentiation in human anaplastic thyroid carcinoma cells. J Clin Endocrinol Metab (2003) 1.47

Mutational spectrum of multiple endocrine neoplasia type 2 and sporadic medullary thyroid carcinoma in taiwan. J Formos Med Assoc (2009) 1.40

Phosphorylation by c-Jun NH2-terminal kinase 1 regulates the stability of transcription factor Sp1 during mitosis. Mol Biol Cell (2008) 1.31

Lovastatin induces apoptosis of anaplastic thyroid cancer cells via inhibition of protein geranylgeranylation and de novo protein synthesis. Endocrinology (2003) 1.09

Lower urinary tract symptoms and urinary flow rates in female patients with hyperthyroidism. Urology (2011) 1.09

Results and predictability of fat-removal orbital decompression for disfiguring graves exophthalmos in an Asian patient population. Am J Ophthalmol (2008) 1.07

Wideband acoustic-reflex test in a test battery to predict middle-ear dysfunction. Hear Res (2009) 1.06

6-shogaol (alkanone from ginger) induces apoptotic cell death of human hepatoma p53 mutant Mahlavu subline via an oxidative stress-mediated caspase-dependent mechanism. J Agric Food Chem (2007) 1.04

Sound-conduction effects on distortion-product otoacoustic emission screening outcomes in newborn infants: test performance of wideband acoustic transfer functions and 1-kHz tympanometry. Ear Hear (2009) 1.03

Serine protease inhibitor (SERPIN) B1 promotes oral cancer cell motility and is over-expressed in invasive oral squamous cell carcinoma. Oral Oncol (2009) 1.02

Characterization of immunological activities of peanut stilbenoids, arachidin-1, piceatannol, and resveratrol on lipopolysaccharide-induced inflammation of RAW 264.7 macrophages. J Agric Food Chem (2007) 1.02

A small-molecule metastasis inhibitor, norcantharidin, downregulates matrix metalloproteinase-9 expression by inhibiting Sp1 transcriptional activity in colorectal cancer cells. Chem Biol Interact (2009) 1.02

Diabetes and thyroid cancer risk: literature review. Exp Diabetes Res (2012) 1.02

Ultrasound-guided fine needle aspiration cytology of parathyroid lesions. A review of 72 cases. Acta Cytol (2002) 1.01

Nodavirus RNA replication protein a induces membrane association of genomic RNA. J Virol (2007) 0.99

Chemical characterization and anti-inflammatory effect of polysaccharides fractionated from submerge-cultured Antrodia camphorata mycelia. J Agric Food Chem (2007) 0.99

Associations between subclinical thyroid disease and metabolic syndrome. Endocr J (2012) 0.98

Combretastatin A-4 inhibits cell growth and metastasis in bladder cancer cells and retards tumour growth in a murine orthotopic bladder tumour model. Br J Pharmacol (2010) 0.97

Associations of remission status and lanreotide treatment with quality of life in patients with treated acromegaly. Eur J Endocrinol (2006) 0.95

Comprehensive genotyping in two homogeneous Graves' disease samples reveals major and novel HLA association alleles. PLoS One (2011) 0.95

Heat shock protein 90 is important for Sp1 stability during mitosis. J Mol Biol (2009) 0.93

Enigmatic ectopic fat: prevalence of nonalcoholic fatty pancreas disease and its associated factors in a Chinese population. J Am Heart Assoc (2014) 0.93

Arecoline downregulates levels of p21 and p27 through the reactive oxygen species/mTOR complex 1 pathway and may contribute to oral squamous cell carcinoma. Cancer Sci (2012) 0.93

Ras-related tumorigenesis is suppressed by BNIP3-mediated autophagy through inhibition of cell proliferation. Neoplasia (2011) 0.92

Estimates of relative risks for cancers in a population after prolonged low-dose-rate radiation exposure: a follow-up assessment from 1983 to 2005. Radiat Res (2008) 0.92

Follicular variant of papillary thyroid carcinoma: diagnostic limitations of fine needle aspiration cytology. Acta Cytol (2005) 0.91

Reversine suppresses oral squamous cell carcinoma via cell cycle arrest and concomitantly apoptosis and autophagy. J Biomed Sci (2012) 0.91

Src family kinases mediate betel quid-induced oral cancer cell motility and could be a biomarker for early invasion in oral squamous cell carcinoma. Neoplasia (2008) 0.91

Involvement of microtubule-associated protein 2 (MAP2) in oral cancer cell motility: a novel biological function of MAP2 in non-neuronal cells. Biochem Biophys Res Commun (2007) 0.90

Glycerol degradation in single-chamber microbial fuel cells. Bioresour Technol (2010) 0.89

Antitumor activity of histone deacetylase inhibitor trichostatin A in osteosarcoma cells. Asian Pac J Cancer Prev (2012) 0.89

Curcumin inhibits HCV replication by induction of heme oxygenase-1 and suppression of AKT. Int J Mol Med (2012) 0.89

A single-nucleotide polymorphism of the DAZL gene promoter confers susceptibility to spermatogenic failure in the Taiwanese Han. Hum Reprod (2012) 0.89

Diabetic ketoacidosis in a patient with acromegaly. J Formos Med Assoc (2007) 0.88

Biological synthesis of gold and silver nanoparticles mediated by the bacteria Bacillus subtilis. J Nanosci Nanotechnol (2010) 0.87

Calreticulin, an endoplasmic reticulum-resident protein, is highly expressed and essential for cell proliferation and migration in oral squamous cell carcinoma. Oral Oncol (2013) 0.87

Proteomics-based identification of plasma biomarkers in oral squamous cell carcinoma. J Pharm Biomed Anal (2012) 0.87

Cortex Moutan Induces Bladder Cancer Cell Death via Apoptosis and Retards Tumor Growth in Mouse Bladders. Evid Based Complement Alternat Med (2013) 0.86

Wogonin, a bioactive flavonoid in herbal tea, inhibits inflammatory cyclooxygenase-2 gene expression in human lung epithelial cancer cells. Mol Nutr Food Res (2008) 0.85

Lovastatin inhibits proliferation of anaplastic thyroid cancer cells through up-regulation of p27 by interfering with the Rho/ROCK-mediated pathway. Biochem Pharmacol (2011) 0.85

Interrenal organogenesis in the zebrafish model. Organogenesis (2007) 0.85

SUMOylated CPAP is required for IKK-mediated NF-κB activation and enhances HBx-induced NF-κB signaling in HCC. J Hepatol (2013) 0.85

Secondary infection and ischemic necrosis after fine needle aspiration for a painful papillary thyroid carcinoma: a case report. Acta Cytol (2006) 0.84

Epigenetic deregulation of the anaplastic lymphoma kinase gene modulates mesenchymal characteristics of oral squamous cell carcinomas. Carcinogenesis (2013) 0.84

Direct interaction of C/EBPdelta and Sp1 at the GC-enriched promoter region synergizes the IL-10 gene transcription in mouse macrophage. J Biomed Sci (2006) 0.84

Translational up-regulation of Aurora-A in EGFR-overexpressed cancer. J Cell Mol Med (2009) 0.84

Role of macrophage infiltration in the orbital fat of patients with Graves' ophthalmopathy. Clin Endocrinol (Oxf) (2008) 0.84

CCAR1 is required for Ngn3-mediated endocrine differentiation. Biochem Biophys Res Commun (2012) 0.84

Observing pretibial myxedema in patients with Graves' disease using digital infrared thermal imaging and high-resolution ultrasonography: for better records, early detection, and further investigation. Eur J Endocrinol (2011) 0.83

Genotype analysis based on intergenic spacer 1 sequences of Trichosporon asahii collected in Taiwan. Med Mycol (2013) 0.83

Multinucleated giant cells in fine needle aspirates. Can they help differentiate papillary thyroid cancer from benign nodular goiter? Acta Cytol (2002) 0.83

Enterovirus 71-induced autophagy increases viral replication and pathogenesis in a suckling mouse model. J Biomed Sci (2014) 0.83

In vivo evidence of duality effects for lovastatin in a nude mouse cancer model. Int J Cancer (2010) 0.83

Reversine induces cell cycle arrest, polyploidy, and apoptosis in human breast cancer cells. Breast Cancer (2012) 0.83

Cytotoxic constituents of the stems of Cinnamomum subavenium. J Nat Prod (2007) 0.82

The molecular mechanism of gypenosides-induced G1 growth arrest of rat hepatic stellate cells. J Ethnopharmacol (2008) 0.82

Betel quid extract promotes oral cancer cell migration by activating a muscarinic M4 receptor-mediated signaling cascade involving SFKs and ERK1/2. Biochem Biophys Res Commun (2010) 0.82

Cytologic features of metastatic papillary thyroid carcinoma in cervical lymph nodes. Acta Cytol (2002) 0.82

Proteomic identification of plasma biomarkers in uterine leiomyoma. Mol Biosyst (2011) 0.82

Decreased GRP78 protein expression is a potential prognostic marker of oral squamous cell carcinoma in Taiwan. J Formos Med Assoc (2010) 0.82

Biosynthesis enhancement and antioxidant and anti-inflammatory activities of peanut (Arachis hypogaea L.) arachidin-1, arachidin-3, and isopentadienylresveratrol. J Agric Food Chem (2006) 0.82

Non-HDL cholesterol level is reliable to be an early predictor for vascular inflammation in type 2 diabetes mellitus. J Clin Endocrinol Metab (2004) 0.82

The application of temperature measurement of the eyes by digital infrared thermal imaging as a prognostic factor of methylprednisolone pulse therapy for Graves' ophthalmopathy. Acta Ophthalmol (2010) 0.81

Plasma proteomic analysis of the critical limb ischemia markers in diabetic patients with hemodialysis. Mol Biosyst (2011) 0.81

Association of TLR7 and TSHR copy number variation with Graves' disease and Graves' ophthalmopathy in Chinese population in Taiwan. BMC Ophthalmol (2014) 0.81

Development and fibronectin signaling requirements of the zebrafish interrenal vessel. PLoS One (2012) 0.81

Rbms3, an RNA-binding protein, mediates the expression of Ptf1a by binding to its 3'UTR during mouse pancreas development. DNA Cell Biol (2012) 0.81

Genomic diversity and molecular differentiation of Riemerella anatipestifer associated with eight outbreaks in five farms. Avian Pathol (2008) 0.81

Characterization of porcine arterial endothelial cells cultured on amniotic membrane, a potential matrix for vascular tissue engineering. Biochem Biophys Res Commun (2007) 0.81

Factors affecting long-term survival of Taiwanese patients with medullary thyroid carcinoma. J Formos Med Assoc (2003) 0.81

Impacts of elevated glycaemic haemoglobin and disease duration on the sensorimotor control of hands in diabetes patients. Diabetes Metab Res Rev (2015) 0.81

Anti-Bladder-Tumor Effect of Baicalein from Scutellaria baicalensis Georgi and Its Application In Vivo. Evid Based Complement Alternat Med (2013) 0.81

Synthesis of gold nanoparticles via an environmentally benign route using a biosurfactant. J Nanosci Nanotechnol (2009) 0.80

Synthesis and biological evaluation of novel C(6) modified baicalein derivatives as antioxidative agents. J Agric Food Chem (2008) 0.80

Autophagy is enhanced and floral development is impaired in AtHVA22d RNA interference Arabidopsis. Plant Physiol (2009) 0.80

Serum C-reactive protein levels correlates better to metabolic syndrome defined by International Diabetes Federation than by NCEP ATP III in men. Diabetes Res Clin Pract (2007) 0.80

Lysosome-related genes are regulated in the orbital fat of patients with graves' ophthalmopathy. Invest Ophthalmol Vis Sci (2008) 0.80

Ionizing radiation induces autophagy in human oral squamous cell carcinoma. J BUON (2014) 0.80

Curcumin-induced heme oxygenase-1 expression plays a negative role for its anti-cancer effect in bladder cancers. Food Chem Toxicol (2012) 0.80

The correlation between TWIST, E-cadherin, and beta-catenin in human bladder cancer. J BUON (2012) 0.80

Hemopexin is up-regulated in plasma from type 1 diabetes mellitus patients: Role of glucose-induced ROS. J Proteomics (2012) 0.80

Areca nut extract induces pyknotic necrosis in serum-starved oral cells via increasing reactive oxygen species and inhibiting GSK3β: an implication for cytopathic effects in betel quid chewers. PLoS One (2013) 0.80

Ossification of the auricles: a forgotten sign in adrenal insufficiency. J Otolaryngol (2002) 0.80

Overexpression of Rho GDP-dissociation inhibitor alpha predicts poor survival in oral squamous cell carcinoma. Oral Oncol (2011) 0.79

Linkage of Graves' disease to the human leucocyte antigen region in the Chinese-Han population in Taiwan. Clin Endocrinol (Oxf) (2007) 0.79

Autophagy induction of reversine on human follicular thyroid cancer cells. Biomed Pharmacother (2012) 0.79

Images in clinical medicine. Lingual thyroid. N Engl J Med (2012) 0.79