Published in Biochim Biophys Acta on April 01, 2012
Standardization of sample collection, isolation and analysis methods in extracellular vesicle research. J Extracell Vesicles (2013) 4.05
Exosomes in cancer development, metastasis, and drug resistance: a comprehensive review. Cancer Metastasis Rev (2013) 2.46
Characterization of human plasma-derived exosomal RNAs by deep sequencing. BMC Genomics (2013) 2.27
Label-free detection and molecular profiling of exosomes with a nano-plasmonic sensor. Nat Biotechnol (2014) 2.15
Cardiomyocytes mediate anti-angiogenesis in type 2 diabetic rats through the exosomal transfer of miR-320 into endothelial cells. J Mol Cell Cardiol (2014) 1.94
Circulating microRNAs as novel biomarkers for diabetes mellitus. Nat Rev Endocrinol (2013) 1.69
Exosomes as intercellular signaling organelles involved in health and disease: basic science and clinical applications. Int J Mol Sci (2013) 1.50
miRNA-26b Overexpression in Ulcerative Colitis-associated Carcinogenesis. Inflamm Bowel Dis (2015) 1.47
Vasopressin Regulates Extracellular Vesicle Uptake by Kidney Collecting Duct Cells. J Am Soc Nephrol (2016) 1.47
The Potential of HLA-G-Bearing Extracellular Vesicles as a Future Element in HLA-G Immune Biology. Front Immunol (2016) 1.45
Exosomes derived from mesenchymal stem cells. Int J Mol Sci (2014) 1.43
Exosomal microRNA miR-92a concentration in serum reflects human brown fat activity. Nat Commun (2016) 1.40
Exosomes derived from hypoxic leukemia cells enhance tube formation in endothelial cells. J Biol Chem (2013) 1.40
Cell based therapies for ischemic stroke: from basic science to bedside. Prog Neurobiol (2013) 1.39
Emerging roles of exosomes in normal and pathological conditions: new insights for diagnosis and therapeutic applications. Front Immunol (2015) 1.37
Isolation of biologically-active exosomes from human plasma. J Immunol Methods (2014) 1.35
Optimized exosome isolation protocol for cell culture supernatant and human plasma. J Extracell Vesicles (2015) 1.32
Exosomes: mediators of neurodegeneration, neuroprotection and therapeutics. Mol Neurobiol (2013) 1.32
Extracellular vesicles as an emerging mechanism of cell-to-cell communication. Endocrine (2012) 1.32
Isolation and quantification of microRNAs from urinary exosomes/microvesicles for biomarker discovery. Int J Biol Sci (2013) 1.26
FedExosomes: Engineering Therapeutic Biological Nanoparticles that Truly Deliver. Pharmaceuticals (Basel) (2013) 1.24
Effect of exosomes derived from multipluripotent mesenchymal stromal cells on functional recovery and neurovascular plasticity in rats after traumatic brain injury. J Neurosurg (2015) 1.22
Soluble ligands for NK cell receptors promote evasion of chronic lymphocytic leukemia cells from NK cell anti-tumor activity. Blood (2013) 1.22
Exosomes are natural carriers of exogenous siRNA to human cells in vitro. Cell Commun Signal (2013) 1.20
Exosome uptake through clathrin-mediated endocytosis and macropinocytosis and mediating miR-21 delivery. J Biol Chem (2014) 1.17
Exosomes as drug delivery vehicles for Parkinson's disease therapy. J Control Release (2015) 1.17
Conserved and host-specific features of influenza virion architecture. Nat Commun (2014) 1.15
Exosomal HIF1α supports invasive potential of nasopharyngeal carcinoma-associated LMP1-positive exosomes. Oncogene (2014) 1.14
Host matrix modulation by tumor exosomes promotes motility and invasiveness. Neoplasia (2013) 1.14
Exosomes in the pathogenesis, diagnostics and therapeutics of liver diseases. J Hepatol (2013) 1.12
Extracellular microRNAs in urologic malignancies: chances and challenges. Int J Mol Sci (2013) 1.11
Comparative analysis of discrete exosome fractions obtained by differential centrifugation. J Extracell Vesicles (2014) 1.11
Exosomes: novel biomarkers for clinical diagnosis. ScientificWorldJournal (2015) 1.11
The complete exosome workflow solution: from isolation to characterization of RNA cargo. Biomed Res Int (2013) 1.10
Neuronal exosomal miRNA-dependent translational regulation of astroglial glutamate transporter GLT1. J Biol Chem (2013) 1.10
Analysis of the RNA content of the exosomes derived from blood serum and urine and its potential as biomarkers. Philos Trans R Soc Lond B Biol Sci (2014) 1.10
Polarization of prostate cancer-associated macrophages is induced by milk fat globule-EGF factor 8 (MFG-E8)-mediated efferocytosis. J Biol Chem (2014) 1.08
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Proteomics (2013) 1.06
Pathologic function and therapeutic potential of exosomes in cardiovascular disease. Biochim Biophys Acta (2014) 1.06
Exosomes and tumor-mediated immune suppression. J Clin Invest (2016) 1.06
Do circulating tumor cells, exosomes, and circulating tumor nucleic acids have clinical utility? A report of the association for molecular pathology. J Mol Diagn (2015) 1.04
Tumor-derived exosomes in oncogenic reprogramming and cancer progression. Cell Mol Life Sci (2014) 1.02
Mesenchymal Stem Cell Exosomes Induce Proliferation and Migration of Normal and Chronic Wound Fibroblasts, and Enhance Angiogenesis In Vitro. Stem Cells Dev (2015) 1.02
Exosomes serve as tumour markers for personalized diagnostics owing to their important role in cancer metastasis. J Extracell Vesicles (2015) 1.02
Exosome in tumour microenvironment: overview of the crosstalk between normal and cancer cells. Biomed Res Int (2014) 1.01
Expression of serum exosomal microRNA-21 in human hepatocellular carcinoma. Biomed Res Int (2014) 1.01
Exosomes in Plasma of Patients with Ovarian Carcinoma: Potential Biomarkers of Tumor Progression and Response to Therapy. Gynecol Obstet (Sunnyvale) (2013) 1.01
Release of luminal exosomes contributes to TLR4-mediated epithelial antimicrobial defense. PLoS Pathog (2013) 1.01
Decreased amyloid-β pathologies by intracerebral loading of glycosphingolipid-enriched exosomes in Alzheimer model mice. J Biol Chem (2014) 1.01
Methods for extracellular vesicles isolation in a hospital setting. Front Immunol (2015) 1.00
Profiling circulating microRNA expression in experimental sepsis using cecal ligation and puncture. PLoS One (2013) 0.99
Exosome delivered anticancer drugs across the blood-brain barrier for brain cancer therapy in Danio rerio. Pharm Res (2015) 0.99
Serum exosomal microRNAs as novel biomarkers for hepatocellular carcinoma. Exp Mol Med (2015) 0.99
Secretion of microvesicular miRNAs in cellular and organismal aging. Exp Gerontol (2012) 0.98
Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein. J Biol Chem (2014) 0.98
Ciliated micropillars for the microfluidic-based isolation of nanoscale lipid vesicles. Lab Chip (2013) 0.98
Active macropinocytosis induction by stimulation of epidermal growth factor receptor and oncogenic Ras expression potentiates cellular uptake efficacy of exosomes. Sci Rep (2015) 0.98
Methods for the extraction and RNA profiling of exosomes. World J Methodol (2013) 0.97
Detection of tumor cell-specific mRNA and protein in exosome-like microvesicles from blood and saliva. PLoS One (2014) 0.95
Exosomal miR-223 Contributes to Mesenchymal Stem Cell-Elicited Cardioprotection in Polymicrobial Sepsis. Sci Rep (2015) 0.94
Exosomes secreted by cortical neurons upon glutamatergic synapse activation specifically interact with neurons. J Extracell Vesicles (2014) 0.94
Tumor-derived exosomes in cancer progression and treatment failure. Oncotarget (2015) 0.94
Bovine milk-derived exosomes for drug delivery. Cancer Lett (2015) 0.93
BMP-regulated exosomes from Drosophila male reproductive glands reprogram female behavior. J Cell Biol (2014) 0.93
Circulating microRNAs, miR-939, miR-595, miR-519d and miR-494, Identify Cirrhotic Patients with HCC. PLoS One (2015) 0.93
The exosomes in tumor immunity. Oncoimmunology (2015) 0.92
Exosomes and microvesicles: identification and targeting by particle size and lipid chemical probes. Chembiochem (2014) 0.91
Exosome proteomics reveals transcriptional regulator proteins with potential to mediate downstream pathways. Cancer Sci (2014) 0.91
Microvesicles as mediators of tissue regeneration. Transl Res (2013) 0.91
Extravillous trophoblast cells-derived exosomes promote vascular smooth muscle cell migration. Front Pharmacol (2014) 0.91
Exosomes from IL-1β stimulated synovial fibroblasts induce osteoarthritic changes in articular chondrocytes. Arthritis Res Ther (2014) 0.90
Transcriptome of extracellular vesicles released by hepatocytes. PLoS One (2013) 0.90
No more monkeying around: primate malaria model systems are key to understanding Plasmodium vivax liver-stage biology, hypnozoites, and relapses. Front Microbiol (2015) 0.90
Non-coding RNAs in saliva: emerging biomarkers for molecular diagnostics. Int J Mol Sci (2015) 0.90
Future microfluidic and nanofluidic modular platforms for nucleic acid liquid biopsy in precision medicine. Biomicrofluidics (2016) 0.90
Exosomes Function in Pro- and Anti-Angiogenesis. Curr Angiogenes (2013) 0.90
Long noncoding RNA dysregulation in ischemic heart failure. J Transl Med (2016) 0.89
Microparticle analysis in disorders of hemostasis and thrombosis. Cytometry A (2015) 0.89
The use of Nanotrap particles technology in capturing HIV-1 virions and viral proteins from infected cells. PLoS One (2014) 0.89
The tetraspanins CD151 and Tspan8 are essential exosome components for the crosstalk between cancer initiating cells and their surrounding. Oncotarget (2015) 0.89
Detection and isolation of circulating exosomes and microvesicles for cancer monitoring and diagnostics using micro-/nano-based devices. Analyst (2016) 0.89
Pancreatic cancer diagnosis by free and exosomal miRNA. World J Gastrointest Pathophysiol (2013) 0.89
Bringing single-molecule spectroscopy to macromolecular protein complexes. Trends Biochem Sci (2012) 0.88
Increased bisecting N-acetylglucosamine and decreased branched chain glycans of N-linked glycoproteins in expressed prostatic secretions associated with prostate cancer progression. Proteomics Clin Appl (2013) 0.87
The emerging roles of tumor-derived exosomes in hematological malignancies. Leukemia (2017) 0.87
Extracellular vesicles and their synthetic analogues in aging and age-associated brain diseases. Biogerontology (2014) 0.87
Suppression of fibrogenic signaling in hepatic stellate cells by Twist1-dependent microRNA-214 expression: Role of exosomes in horizontal transfer of Twist1. Am J Physiol Gastrointest Liver Physiol (2015) 0.87
Proteomic studies of urinary biomarkers for prostate, bladder and kidney cancers. Nat Rev Urol (2013) 0.87
A comparison of the ability of levels of urinary biomarker proteins and exosomal mRNA to predict outcomes after renal transplantation. PLoS One (2014) 0.86
The endocytic receptor megalin and its associated proteins in proximal tubule epithelial cells. Membranes (Basel) (2014) 0.86
Exosomal Proteome Profiling: A Potential Multi-Marker Cellular Phenotyping Tool to Characterize Hypoxia-Induced Radiation Resistance in Breast Cancer. Proteomes (2013) 0.86
Small but mighty: microparticles as mediators of tumor progression. Cancer Microenviron (2014) 0.86
MicroRNA expression signatures determine prognosis and survival in glioblastoma multiforme--a systematic overview. Mol Neurobiol (2014) 0.85
Osteoprotegerin in exosome-like vesicles from human cultured tubular cells and urine. PLoS One (2013) 0.85
Systemic administration of cell-free exosomes generated by human bone marrow derived mesenchymal stem cells cultured under 2D and 3D conditions improves functional recovery in rats after traumatic brain injury. Neurochem Int (2016) 0.85
Human aqueous humor exosomes. Exp Eye Res (2015) 0.85
HLA-G as a tolerogenic molecule in transplantation and pregnancy. J Immunol Res (2014) 0.85
Isolation of extracellular vesicles: Determining the correct approach (Review). Int J Mol Med (2015) 0.85
Isolation of exosomes by differential centrifugation: Theoretical analysis of a commonly used protocol. Sci Rep (2015) 0.85
Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1(+/-)p53(-/-) mice. Cancer Cell (2004) 5.95
Radial glia cells are candidate stem cells of ependymoma. Cancer Cell (2005) 5.21
The tumor suppressors Ink4c and p53 collaborate independently with Patched to suppress medulloblastoma formation. Genes Dev (2005) 2.14
Early embryonic lethality in mice with targeted deletion of the CTP:phosphocholine cytidylyltransferase alpha gene (Pcyt1a). Mol Cell Biol (2005) 1.34
Binding of purified Reelin to ApoER2 and VLDLR mediates tyrosine phosphorylation of Disabled-1. Brain Res Mol Brain Res (2003) 1.23
The complete exosome workflow solution: from isolation to characterization of RNA cargo. Biomed Res Int (2013) 1.10
Selection of hyperfunctional siRNAs with improved potency and specificity. Nucleic Acids Res (2009) 1.09
Cyclin-dependent kinase 5 phosphorylates disabled 1 independently of Reelin signaling. J Neurosci (2002) 1.05
Stem-loop RT-PCR quantification of siRNAs in vitro and in vivo. Oligonucleotides (2009) 1.05
Tyrosine phosphorylated Disabled 1 recruits Crk family adapter proteins. Biochem Biophys Res Commun (2004) 1.03
Interaction of Disabled-1 and the GTPase activating protein Dab2IP in mouse brain. Brain Res Mol Brain Res (2003) 0.97
A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res (2004) 0.96
The human salivary RNA transcriptome revealed by massively parallel sequencing. Clin Chem (2012) 0.95
Gene expression profiles of mouse retinas during the second and third postnatal weeks. Brain Res (2006) 0.91
LNA incorporated siRNAs exhibit lower off-target effects compared to 2'-OMethoxy in cell phenotypic assays and microarray analysis. Nucleic Acids Symp Ser (Oxf) (2008) 0.87
An arrayed RNA interference genome-wide screen identifies candidate genes involved in the MicroRNA 21 biogenesis pathway. Assay Drug Dev Technol (2012) 0.85
Ectopic expression of reelin alters migration of sympathetic preganglionic neurons in the spinal cord. J Comp Neurol (2009) 0.84
Components of the reelin signaling pathway are expressed in the spinal cord. J Comp Neurol (2004) 0.83
Temporal gene expression analysis of human coronary artery endothelial cells treated with Simvastatin. Gene Expr (2008) 0.78
Optimization of transfection conditions and analysis of siRNA potency using real-time PCR. Methods Mol Biol (2011) 0.77
Quantification of siRNAs in vitro and in vivo. Methods Mol Biol (2011) 0.76
MicroSEQ Salmonella spp. Detection Kit using the Pathatrix 10-Pooling Salmonella spp. Kit linked protocol method modification. Performance Tested Method 031001. J AOAC Int (2014) 0.75