Recognition of sialylated poly-N-acetyllactosamine chains on N- and O-linked glycans by human and avian influenza A virus hemagglutinins.

PubWeight™: 1.23‹?› | Rank: Top 10%

🔗 View Article (PMC 3517101)

Published in Angew Chem Int Ed Engl on April 13, 2012

Authors

Corwin M Nycholat1, Ryan McBride, Damian C Ekiert, Rui Xu, Janani Rangarajan, Wenjie Peng, Nahid Razi, Michel Gilbert, Warren Wakarchuk, Ian A Wilson, James C Paulson

Author Affiliations

1: Department of Chemical Physiology, The Scripps Research Institute, La Jolla, CA 92037, USA.

Articles citing this

Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans. PLoS Pathog (2013) 2.66

Glycomic analysis of human respiratory tract tissues and correlation with influenza virus infection. PLoS Pathog (2013) 1.62

Combining 3D structure with glycan array data provides insight into the origin of glycan specificity. Glycobiology (2016) 1.13

H5N1 receptor specificity as a factor in pandemic risk. Virus Res (2013) 1.11

Hemagglutinin receptor specificity and structural analyses of respiratory droplet-transmissible H5N1 viruses. J Virol (2013) 1.08

Human H3N2 Influenza Viruses Isolated from 1968 To 2012 Show Varying Preference for Receptor Substructures with No Apparent Consequences for Disease or Spread. PLoS One (2013) 1.07

Infection of swine ex vivo tissues with avian viruses including H7N9 and correlation with glycomic analysis. Influenza Other Respir Viruses (2013) 0.95

Global comparisons of lectin-glycan interactions using a database of analyzed glycan array data. Mol Cell Proteomics (2013) 0.87

Determining lectin specificity from glycan array data using motif segregation and GlycoSearch software. Curr Protoc Chem Biol (2013) 0.85

Helicobacter pylori β1,3-N-acetylglucosaminyltransferase for versatile synthesis of type 1 and type 2 poly-LacNAcs on N-linked, O-linked and I-antigen glycans. Glycobiology (2012) 0.85

Synthesis of biologically active N- and O-linked glycans with multisialylated poly-N-acetyllactosamine extensions using P. damsela α2-6 sialyltransferase. J Am Chem Soc (2013) 0.84

Structure and receptor binding specificity of hemagglutinin H13 from avian influenza A virus H13N6. J Virol (2013) 0.83

Investigating virus-glycan interactions using glycan microarrays. Curr Opin Virol (2014) 0.83

An ultrasensitive impedimetric glycan biosensor with controlled glycan density for detection of lectins and influenza hemagglutinins. Chem Commun (Camb) (2015) 0.83

Recent H3N2 Viruses Have Evolved Specificity for Extended, Branched Human-type Receptors, Conferring Potential for Increased Avidity. Cell Host Microbe (2016) 0.81

Amino acid residues at positions 222 and 227 of the hemagglutinin together with the neuraminidase determine binding of H5 avian influenza viruses to sialyl Lewis X. Arch Virol (2015) 0.81

Glycan fingerprints: calculating diversity in glycan libraries. ACS Chem Biol (2012) 0.81

Unmasking of CD22 Co-receptor on Germinal Center B-cells Occurs by Alternative Mechanisms in Mouse and Man. J Biol Chem (2015) 0.79

The detection and discovery of glycan motifs in biological samples using lectins and antibodies: new methods and opportunities. Adv Cancer Res (2015) 0.79

Donor substrate promiscuity of bacterial β1-3-N-acetylglucosaminyltransferases and acceptor substrate flexibility of β1-4-galactosyltransferases. Bioorg Med Chem (2016) 0.78

A Siglec-like sialic-acid-binding motif revealed in an adenovirus capsid protein. Glycobiology (2012) 0.78

Glycosylation changes in the globular head of H3N2 influenza hemagglutinin modulate receptor binding without affecting virus virulence. Sci Rep (2016) 0.78

Characterizing Protein Glycosylation through On-Chip Glycan Modification and Probing. Anal Chem (2016) 0.77

Identification of Stabilizing Mutations in an H5 Hemagglutinin Influenza Virus Protein. J Virol (2015) 0.75

Articles cited by this

Structure and receptor specificity of the hemagglutinin from an H5N1 influenza virus. Science (2006) 10.04

Transmission and pathogenesis of swine-origin 2009 A(H1N1) influenza viruses in ferrets and mice. Science (2009) 8.61

Receptor specificity in human, avian, and equine H2 and H3 influenza virus isolates. Virology (1994) 8.06

Glycan microarray analysis of the hemagglutinins from modern and pandemic influenza viruses reveals different receptor specificities. J Mol Biol (2005) 6.17

Glycan topology determines human adaptation of avian H5N1 virus hemagglutinin. Nat Biotechnol (2008) 4.37

Host range restriction and pathogenicity in the context of influenza pandemic. Emerg Infect Dis (2006) 3.27

Receptor-binding specificity of pandemic influenza A (H1N1) 2009 virus determined by carbohydrate microarray. Nat Biotechnol (2009) 3.07

Glycan microarray technologies: tools to survey host specificity of influenza viruses. Nat Rev Microbiol (2006) 2.83

Evolving complexities of influenza virus and its receptors. Trends Microbiol (2008) 2.49

The influenza virus enigma. Cell (2009) 2.48

X-ray structure of the hemagglutinin of a potential H3 avian progenitor of the 1968 Hong Kong pandemic influenza virus. Virology (2003) 2.23

Glycan analysis and influenza A virus infection of primary swine respiratory epithelial cells: the importance of NeuAc{alpha}2-6 glycans. J Biol Chem (2010) 1.53

Glycans as receptors for influenza pathogenesis. Glycoconj J (2010) 1.38

Expression cloning of cDNA encoding a human beta-1,3-N-acetylglucosaminyltransferase that is essential for poly-N-acetyllactosamine synthesis. Proc Natl Acad Sci U S A (1997) 1.29

Chemoenzymatic synthesis of glycan libraries. Methods Enzymol (2006) 1.10

Efficient preparation of natural and synthetic galactosides with a recombinant beta-1,4-galactosyltransferase-/UDP-4'-gal epimerase fusion protein. J Org Chem (2001) 1.00

Chemo-enzymatic synthesis of poly-N-acetyllactosamine (poly-LacNAc) structures and their characterization for CGL2-galectin-mediated binding of ECM glycoproteins to biomaterial surfaces. Glycoconj J (2008) 0.97

Complementary acceptor and site specificities of Fuc-TIV and Fuc-TVII allow effective biosynthesis of sialyl-TriLex and related polylactosamines present on glycoprotein counterreceptors of selectins. J Biol Chem (1998) 0.94

A new reactivity-based one-pot synthesis of N-acetyllactosamine oligomers. J Org Chem (2003) 0.91

Articles by these authors

Antibody recognition of a highly conserved influenza virus epitope. Science (2009) 11.26

Broad neutralization coverage of HIV by multiple highly potent antibodies. Nature (2011) 11.07

Structure and receptor specificity of the hemagglutinin from an H5N1 influenza virus. Science (2006) 10.04

HIV vaccine design and the neutralizing antibody problem. Nat Immunol (2004) 9.48

Siglecs and their roles in the immune system. Nat Rev Immunol (2007) 7.98

The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of alpha1-->2 mannose residues on the outer face of gp120. J Virol (2002) 7.82

Structure of a V3-containing HIV-1 gp120 core. Science (2005) 7.69

How TCRs bind MHCs, peptides, and coreceptors. Annu Rev Immunol (2006) 7.57

Printed covalent glycan array for ligand profiling of diverse glycan binding proteins. Proc Natl Acad Sci U S A (2004) 7.55

Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9. Nature (2011) 7.20

Structure of the uncleaved human H1 hemagglutinin from the extinct 1918 influenza virus. Science (2004) 6.70

Antibody domain exchange is an immunological solution to carbohydrate cluster recognition. Science (2003) 6.68

Glycan microarray analysis of the hemagglutinins from modern and pandemic influenza viruses reveals different receptor specificities. J Mol Biol (2005) 6.17

Structural basis of preexisting immunity to the 2009 H1N1 pandemic influenza virus. Science (2010) 6.10

Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline. Proc Natl Acad Sci U S A (2002) 6.00

A highly conserved neutralizing epitope on group 2 influenza A viruses. Science (2011) 5.66

Fine mapping of the interaction of neutralizing and nonneutralizing monoclonal antibodies with the CD4 binding site of human immunodeficiency virus type 1 gp120. J Virol (2003) 5.59

Crystal structure of a soluble cleaved HIV-1 envelope trimer. Science (2013) 5.53

Natural killer T cells recognize diacylglycerol antigens from pathogenic bacteria. Nat Immunol (2006) 5.51

A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield. Science (2011) 5.44

A single amino acid substitution in 1918 influenza virus hemagglutinin changes receptor binding specificity. J Virol (2005) 4.71

Cryo-EM structure of a fully glycosylated soluble cleaved HIV-1 envelope trimer. Science (2013) 4.61

Computational design of proteins targeting the conserved stem region of influenza hemagglutinin. Science (2011) 4.42

Structures of the CCR5 N terminus and of a tyrosine-sulfated antibody with HIV-1 gp120 and CD4. Science (2007) 4.35

Broadly neutralizing anti-HIV antibody 4E10 recognizes a helical conformation of a highly conserved fusion-associated motif in gp41. Immunity (2005) 4.26

A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies. PLoS Pathog (2013) 4.23

Recapitulation of IVIG anti-inflammatory activity with a recombinant IgG Fc. Science (2008) 4.11

New world bats harbor diverse influenza A viruses. PLoS Pathog (2013) 4.10

Protein production and purification. Nat Methods (2008) 3.97

Crystal structure of human toll-like receptor 3 (TLR3) ectodomain. Science (2005) 3.72

Characterization of H7N9 influenza A viruses isolated from humans. Nature (2013) 3.71

Antibody vs. HIV in a clash of evolutionary titans. Proc Natl Acad Sci U S A (2005) 3.57

Rational HIV immunogen design to target specific germline B cell receptors. Science (2013) 3.55

Broadly neutralizing antibodies present new prospects to counter highly antigenically diverse viruses. Science (2012) 3.53

Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors. Nature (2008) 3.47

Highly conserved protective epitopes on influenza B viruses. Science (2012) 3.47

Contemporary North American influenza H7 viruses possess human receptor specificity: Implications for virus transmissibility. Proc Natl Acad Sci U S A (2008) 3.45

Exploration of uncharted regions of the protein universe. PLoS Biol (2009) 3.41

Structural rationale for the broad neutralization of HIV-1 by human monoclonal antibody 447-52D. Structure (2004) 3.31

A Blueprint for HIV Vaccine Discovery. Cell Host Microbe (2012) 3.27

Vaccination with a synthetic peptide from the influenza virus hemagglutinin provides protection against distinct viral subtypes. Proc Natl Acad Sci U S A (2010) 3.24

A dynamic knockout reveals that conformational fluctuations influence the chemical step of enzyme catalysis. Science (2011) 3.19

In vitro evolution of H5N1 avian influenza virus toward human-type receptor specificity. Virology (2011) 3.19

Structure and function of a potent agonist for the semi-invariant natural killer T cell receptor. Nat Immunol (2005) 3.12

Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120. Nat Struct Mol Biol (2013) 3.11

Crystal structure of a bacterial cocaine esterase. Nat Struct Biol (2002) 3.06

Recent avian H5N1 viruses exhibit increased propensity for acquiring human receptor specificity. J Mol Biol (2008) 3.00

Asymmetric recognition of the HIV-1 trimer by broadly neutralizing antibody PG9. Proc Natl Acad Sci U S A (2013) 2.96

Beta2 adrenergic receptor activation. Modulation of the proline kink in transmembrane 6 by a rotamer toggle switch. J Biol Chem (2002) 2.87

Replication and transmission of H9N2 influenza viruses in ferrets: evaluation of pandemic potential. PLoS One (2008) 2.86

Glycan microarray technologies: tools to survey host specificity of influenza viruses. Nat Rev Microbiol (2006) 2.83

Genetic and phenotypic analyses of human immunodeficiency virus type 1 escape from a small-molecule CCR5 inhibitor. J Virol (2004) 2.80

HIV-1 and influenza antibodies: seeing antigens in new ways. Nat Immunol (2009) 2.80

Structure and function of broadly reactive antibody PG16 reveal an H3 subdomain that mediates potent neutralization of HIV-1. Proc Natl Acad Sci U S A (2010) 2.77

Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans. PLoS Pathog (2013) 2.66

Structural characterization of the 1918 influenza virus H1N1 neuraminidase. J Virol (2008) 2.63

T cell activation by lipopeptide antigens. Science (2004) 2.59

Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12. Proc Natl Acad Sci U S A (2005) 2.50

A general strategy for the chemoenzymatic synthesis of asymmetrically branched N-glycans. Science (2013) 2.49

High-efficiency labeling of sialylated glycoproteins on living cells. Nat Methods (2009) 2.46

Cross-neutralization of influenza A viruses mediated by a single antibody loop. Nature (2012) 2.44

Electron tomography at 2.4-ångström resolution. Nature (2012) 2.39

Trimeric HIV-1 glycoprotein gp140 immunogens and native HIV-1 envelope glycoproteins display the same closed and open quaternary molecular architectures. Proc Natl Acad Sci U S A (2011) 2.38

An affinity-enhanced neutralizing antibody against the membrane-proximal external region of human immunodeficiency virus type 1 gp41 recognizes an epitope between those of 2F5 and 4E10. J Virol (2007) 2.35

Three-dimensional structural view of the central metabolic network of Thermotoga maritima. Science (2009) 2.33

Effect of receptor binding domain mutations on receptor binding and transmissibility of avian influenza H5N1 viruses. Virology (2011) 2.28

Tafamidis, a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade. Proc Natl Acad Sci U S A (2012) 2.27

XtalPred: a web server for prediction of protein crystallizability. Bioinformatics (2007) 2.26

The molecular interaction of CAR and JAML recruits the central cell signal transducer PI3K. Science (2010) 2.26

The crucial role of Campylobacter jejuni genes in anti-ganglioside antibody induction in Guillain-Barre syndrome. J Clin Invest (2004) 2.25

Homomultimeric complexes of CD22 in B cells revealed by protein-glycan cross-linking. Nat Chem Biol (2005) 2.22

Crystal structure of CD1a in complex with a sulfatide self antigen at a resolution of 2.15 A. Nat Immunol (2003) 2.20

Structural basis for CD1d presentation of a sulfatide derived from myelin and its implications for autoimmunity. J Exp Med (2005) 2.18

In vivo targeting of B-cell lymphoma with glycan ligands of CD22. Blood (2010) 2.17

Optimization of affinity, specificity and function of designed influenza inhibitors using deep sequencing. Nat Biotechnol (2012) 2.14

Comparative efficacy of neutralizing antibodies elicited by recombinant hemagglutinin proteins from avian H5N1 influenza virus. J Virol (2008) 2.14

Structural basis of steroid hormone perception by the receptor kinase BRI1. Nature (2011) 2.12