PubRank

Hidefumi Fukushima

Author PubWeight™ 35.99‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Selective inhibition of NF-kappa B blocks osteoclastogenesis and prevents inflammatory bone destruction in vivo. Nat Med 2004 2.94
2 mTOR drives its own activation via SCF(βTrCP)-dependent degradation of the mTOR inhibitor DEPTOR. Mol Cell 2011 2.03
3 Cdh1 regulates osteoblast function through an APC/C-independent modulation of Smurf1. Mol Cell 2011 1.87
4 Tumor suppressor functions of FBW7 in cancer development and progression. FEBS Lett 2012 1.64
5 Acetylation-dependent regulation of Skp2 function. Cell 2012 1.40
6 Tumor necrosis factor alpha represses bone morphogenetic protein (BMP) signaling by interfering with the DNA binding of Smads through the activation of NF-kappaB. J Biol Chem 2009 1.24
7 Skp2: a novel potential therapeutic target for prostate cancer. Biochim Biophys Acta 2011 1.21
8 SCF(β-TRCP) suppresses angiogenesis and thyroid cancer cell migration by promoting ubiquitination and destruction of VEGF receptor 2. J Exp Med 2012 1.18
9 Mcl-1 ubiquitination and destruction. Oncotarget 2011 1.17
10 The Fbw7 and betaTRCP E3 ubiquitin ligases and their roles in tumorigenesis. Front Biosci (Landmark Ed) 2012 1.12
11 The two faces of FBW7 in cancer drug resistance. Bioessays 2011 1.08
12 Emerging roles of the FBW7 tumour suppressor in stem cell differentiation. EMBO Rep 2011 1.00
13 Novel insights into the molecular mechanisms governing Mdm2 ubiquitination and destruction. Oncotarget 2010 0.98
14 Skp2 is a promising therapeutic target in breast cancer. Front Oncol 2012 0.95
15 Processing of the NF-kappa B2 precursor p100 to p52 is critical for RANKL-induced osteoclast differentiation. J Bone Miner Res 2010 0.93
16 Disruption of NF-κB1 prevents bone loss caused by mechanical unloading. J Bone Miner Res 2013 0.89
17 DNA damage-induced activation of ATM promotes β-TRCP-mediated Mdm2 ubiquitination and destruction. Oncotarget 2012 0.88
18 Mechanism and role of high-potassium-induced reduction of intracellular Ca2+ concentration in rat osteoclasts. Am J Physiol Cell Physiol 2003 0.87
19 Low-level laser irradiation enhances BMP-induced osteoblast differentiation by stimulating the BMP/Smad signaling pathway. J Cell Biochem 2010 0.85
20 RANKL-stimulated TNFalpha production in osteoclast precursor cells promotes osteoclastogenesis by modulating RANK signaling pathways. Biochem Biophys Res Commun 2007 0.84
21 The current and future therapies of bone regeneration to repair bone defects. Int J Dent 2012 0.84
22 Regulation of APC(Cdh1) E3 ligase activity by the Fbw7/cyclin E signaling axis contributes to the tumor suppressor function of Fbw7. Cell Res 2013 0.83
23 Lactacystin, a proteasome inhibitor, enhances BMP-induced osteoblastic differentiation by increasing active Smads. Biochem Biophys Res Commun 2011 0.83
24 Accumulation of p100, a precursor of NF-κB2, enhances osteoblastic differentiation in vitro and bone formation in vivo in aly/aly mice. Mol Endocrinol 2012 0.82
25 Oral squamous cell carcinoma cells modulate osteoclast function by RANKL-dependent and -independent mechanisms. Cancer Lett 2008 0.82
26 Prostaglandin E2 activates outwardly rectifying Cl(-) channels via a cAMP-dependent pathway and reduces cell motility in rat osteoclasts. Am J Physiol Cell Physiol 2004 0.82
27 p130Cas, Crk-associated substrate, plays important roles in osteoclastic bone resorption. J Bone Miner Res 2013 0.81
28 RelB-induced expression of Cot, an MAP3K family member, rescues RANKL-induced osteoclastogenesis in alymphoplasia mice by promoting NF-κB2 processing by IKKα. J Biol Chem 2014 0.81
29 Inhibition of BMP2-induced bone formation by the p65 subunit of NF-κB via an interaction with Smad4. Mol Endocrinol 2014 0.80
30 The inhibition of RANKL/RANK signaling by osteoprotegerin suppresses bone invasion by oral squamous cell carcinoma cells. Carcinogenesis 2011 0.80
31 Calcitonin in human odontoclasts regulates root resorption activity via protein kinase A. J Bone Miner Metab 2004 0.80
32 Characteristics of ClC7 Cl- channels and their inhibition in mutant (G215R) associated with autosomal dominant osteopetrosis type II in native osteoclasts and hClcn7 gene-expressing cells. Pflugers Arch 2009 0.78
33 Calcitonin inhibits proton extrusion in resorbing rat osteoclasts via protein kinase A. Pflugers Arch 2003 0.76
34 SCFβ-TRCP regulates osteoclastogenesis via promoting CYLD ubiquitination. Oncotarget 2014 0.75
35 Occlusal guidance of two Kabuki make-up syndrome patients: case reports. J Clin Pediatr Dent 2004 0.75
36 Mineral trioxide aggregate solution inhibits osteoclast differentiation through the maintenance of osteoprotegerin expression in osteoblasts. J Biomed Mater Res A 2010 0.75