Published in J Innate Immun on April 11, 2012
Phenotypic transitions of macrophages orchestrate tissue repair. Am J Pathol (2013) 1.36
Macrophage phenotype controls long-term AKI outcomes--kidney regeneration versus atrophy. J Am Soc Nephrol (2013) 1.31
Blocking interleukin-1β induces a healing-associated wound macrophage phenotype and improves healing in type 2 diabetes. Diabetes (2013) 1.22
Astragalus membranaceus inhibits inflammation via phospho-P38 mitogen-activated protein kinase (MAPK) and nuclear factor (NF)-κB pathways in advanced glycation end product-stimulated macrophages. Int J Mol Sci (2012) 0.99
Recombinant human interleukin-1 receptor antagonist in severe traumatic brain injury: a phase II randomized control trial. J Cereb Blood Flow Metab (2014) 0.97
LRIG1 inhibits STAT3-dependent inflammation to maintain corneal homeostasis. J Clin Invest (2013) 0.96
Disclosure of the Culprits: Macrophages-Versatile Regulators of Wound Healing. Adv Wound Care (New Rochelle) (2013) 0.94
Macrophage activation and skeletal muscle healing following traumatic injury. J Pathol (2014) 0.91
Quantitative expression of C-type lectin receptors in humans and mice. Int J Mol Sci (2012) 0.91
Stroma as an Active Player in the Development of the Tumor Microenvironment. Cancer Microenviron (2014) 0.89
Immune cascades in human intervertebral disc: the pros and cons. Int J Clin Exp Pathol (2013) 0.88
Macrophages: plastic solutions to environmental heterogeneity. Inflamm Res (2013) 0.87
Four danger response programs determine glomerular and tubulointerstitial kidney pathology: clotting, inflammation, epithelial and mesenchymal healing. Organogenesis (2012) 0.86
The impact of breed and tissue compartment on the response of pig macrophages to lipopolysaccharide. BMC Genomics (2013) 0.83
Danger control programs cause tissue injury and remodeling. Int J Mol Sci (2013) 0.82
Epigenetics and the overhealing wound: the role of DNA methylation in fibrosis. Fibrogenesis Tissue Repair (2015) 0.81
Addressing the Global Burden of Trauma in Major Surgery. Front Surg (2015) 0.79
Alveolar macrophages of GM-CSF knockout mice exhibit mixed M1 and M2 phenotypes. BMC Immunol (2013) 0.79
The autodigestion hypothesis for shock and multi-organ failure. Ann Biomed Eng (2013) 0.78
The Immune System in Tissue Environments Regaining Homeostasis after Injury: Is "Inflammation" Always Inflammation? Mediators Inflamm (2016) 0.78
Recombinant human interleukin-1 receptor antagonist promotes M1 microglia biased cytokines and chemokines following human traumatic brain injury. J Cereb Blood Flow Metab (2015) 0.78
Expression of folate receptors alpha and beta in normal and cancerous gynecologic tissues: correlation of expression of the beta isoform with macrophage markers. J Ovarian Res (2015) 0.77
Links between coagulation, inflammation, regeneration, and fibrosis in kidney pathology. Lab Invest (2016) 0.77
Photobiomodulation with 660-nm and 780-nm laser on activated J774 macrophage-like cells: Effect on M1 inflammatory markers. J Photochem Photobiol B (2015) 0.76
Trypsin, Tryptase, and Thrombin Polarize Macrophages towards a Pro-Fibrotic M2a Phenotype. PLoS One (2015) 0.75
CSF-1 regulates the function of monocytes in Crohn's disease patients in remission. Sci Rep (2017) 0.75
Cleavage of Type I Collagen by Fibroblast Activation Protein-α Enhances Class A Scavenger Receptor Mediated Macrophage Adhesion. PLoS One (2016) 0.75
S1P Provokes Tumor Lymphangiogenesis via Macrophage-Derived Mediators Such as IL-1β or Lipocalin-2. Mediators Inflamm (2017) 0.75
Mechanisms that determine nanocarrier targeting to healthy versus inflamed lung regions. Nanomedicine (2017) 0.75
Calcium oxalate crystals induce renal inflammation by NLRP3-mediated IL-1β secretion. J Clin Invest (2012) 1.91
Ligands to nucleic acid-specific toll-like receptors and the onset of lupus nephritis. J Am Soc Nephrol (2006) 1.80
The immune system and kidney disease: basic concepts and clinical implications. Nat Rev Immunol (2013) 1.76
MDM2 (murine double minute-2) links inflammation and tubular cell healing during acute kidney injury in mice. Kidney Int (2012) 1.74
Histones from dying renal cells aggravate kidney injury via TLR2 and TLR4. J Am Soc Nephrol (2012) 1.73
Uromodulin triggers IL-1β-dependent innate immunity via the NLRP3 inflammasome. J Am Soc Nephrol (2012) 1.72
Viral double-stranded RNA aggravates lupus nephritis through Toll-like receptor 3 on glomerular mesangial cells and antigen-presenting cells. J Am Soc Nephrol (2005) 1.69
Inhibition of Toll-like receptor-7 (TLR-7) or TLR-7 plus TLR-9 attenuates glomerulonephritis and lung injury in experimental lupus. J Am Soc Nephrol (2007) 1.68
Histones trigger sterile inflammation by activating the NLRP3 inflammasome. Eur J Immunol (2013) 1.65
Beyond the LUNAR trial. Efficacy of rituximab in refractory lupus nephritis. Nephrol Dial Transplant (2012) 1.58
Expression and regulation of Toll-like receptors in lupus-like immune complex glomerulonephritis of MRL-Fas(lpr) mice. Nephrol Dial Transplant (2006) 1.55
Nrf2 signalling promotes ex vivo tubular epithelial cell survival and regeneration via murine double minute (MDM)-2. Nephrol Dial Transplant (2013) 1.46
Spiegelmer inhibition of CCL2/MCP-1 ameliorates lupus nephritis in MRL-(Fas)lpr mice. J Am Soc Nephrol (2007) 1.44
Lymphotoxin β receptor signaling promotes development of autoimmune pancreatitis. Gastroenterology (2012) 1.43
Chemokine receptor CCR1 but not CCR5 mediates leukocyte recruitment and subsequent renal fibrosis after unilateral ureteral obstruction. J Am Soc Nephrol (2004) 1.41
Chemokine receptors Ccr1, Ccr2, and Ccr5 mediate neutrophil migration to postischemic tissue. J Leukoc Biol (2005) 1.40
Toll-like receptor-4: renal cells and bone marrow cells signal for neutrophil recruitment during pyelonephritis. Kidney Int (2005) 1.35
G-rich DNA suppresses systemic lupus. J Am Soc Nephrol (2005) 1.35
The pathogenesis of lupus nephritis. J Am Soc Nephrol (2013) 1.33
Toll-like receptor-7 modulates immune complex glomerulonephritis. J Am Soc Nephrol (2005) 1.32
Macrophage phenotype controls long-term AKI outcomes--kidney regeneration versus atrophy. J Am Soc Nephrol (2013) 1.31
Molecular mechanisms of crystal-related kidney inflammation and injury. Implications for cholesterol embolism, crystalline nephropathies and kidney stone disease. Nephrol Dial Transplant (2013) 1.30
TIR8/SIGIRR: an IL-1R/TLR family member with regulatory functions in inflammation and T cell polarization. Trends Immunol (2009) 1.30
Resident dendritic cells prevent postischemic acute renal failure by help of single Ig IL-1 receptor-related protein. J Immunol (2009) 1.28
Macrophages and fibrosis: How resident and infiltrating mononuclear phagocytes orchestrate all phases of tissue injury and repair. Biochim Biophys Acta (2012) 1.27
The role of interstitial macrophages in nephropathy of type 2 diabetic db/db mice. Am J Pathol (2007) 1.27
Quantitative expression of RIG-like helicase, NOD-like receptor and inflammasome-related mRNAs in humans and mice. Int Immunol (2010) 1.26
Tir8/Sigirr prevents murine lupus by suppressing the immunostimulatory effects of lupus autoantigens. J Exp Med (2008) 1.24
CCR1 blockade reduces interstitial inflammation and fibrosis in mice with glomerulosclerosis and nephrotic syndrome. Kidney Int (2004) 1.24
Late onset of Ccl2 blockade with the Spiegelmer mNOX-E36-3'PEG prevents glomerulosclerosis and improves glomerular filtration rate in db/db mice. Am J Pathol (2008) 1.24
Requirement of Toll-like receptor 7 for pristane-induced production of autoantibodies and development of murine lupus nephritis. Arthritis Rheum (2008) 1.20
Delayed chemokine receptor 1 blockade prolongs survival in collagen 4A3-deficient mice with Alport disease. J Am Soc Nephrol (2005) 1.19
Systematic analysis of a novel human renal glomerulus-enriched gene expression dataset. PLoS One (2010) 1.18
Therapeutic efficacy of bifunctional siRNA combining TGF-β1 silencing with RIG-I activation in pancreatic cancer. Cancer Res (2013) 1.17
Extracellular histones in tissue injury and inflammation. J Mol Med (Berl) (2014) 1.17
Functional consequences of integrin-linked kinase activation in podocyte damage. Kidney Int (2005) 1.14
The contribution of B cells to renal interstitial inflammation. Am J Pathol (2007) 1.14
Loss of Roquin induces early death and immune deregulation but not autoimmunity. J Exp Med (2011) 1.11
Cutting edge: cyclic polypeptide and aminoglycoside antibiotics trigger IL-1β secretion by activating the NLRP3 inflammasome. J Immunol (2011) 1.09
Bacterial lipopeptide triggers massive albuminuria in murine lupus nephritis by activating Toll-like receptor 2 at the glomerular filtration barrier. Immunology (2008) 1.09
Anti-GBM glomerulonephritis involves IL-1 but is independent of NLRP3/ASC inflammasome-mediated activation of caspase-1. PLoS One (2011) 1.08
An orally active chemokine receptor CCR2 antagonist prevents glomerulosclerosis and renal failure in type 2 diabetes. Kidney Int (2011) 1.07
Stem cell therapy for Alport syndrome: the hope beyond the hype. Nephrol Dial Transplant (2008) 1.07
Phenotyping renal leukocyte subsets by four-color flow cytometry: characterization of chemokine receptor expression. Nephron Exp Nephrol (2003) 1.06
The role of innate immunity in autoimmune tissue injury. Curr Opin Rheumatol (2008) 1.06
Canonical and non-canonical effects of the NLRP3 inflammasome in kidney inflammation and fibrosis. Nephrol Dial Transplant (2013) 1.06
B-cell-attracting chemokine CXCL13 as a marker of disease activity and renal involvement in systemic lupus erythematosus (SLE). Nephrol Dial Transplant (2009) 1.06
Dual blockade of the homeostatic chemokine CXCL12 and the proinflammatory chemokine CCL2 has additive protective effects on diabetic kidney disease. Am J Pathol (2011) 1.05
Progressive glomerulosclerosis in type 2 diabetes is associated with renal histone H3K9 and H3K23 acetylation, H3K4 dimethylation and phosphorylation at serine 10. Nephrol Dial Transplant (2010) 1.05
Viral RNA and DNA trigger common antiviral responses in mesangial cells. J Am Soc Nephrol (2009) 1.04
Ischemia reperfusion induces IFN regulatory factor 4 in renal dendritic cells, which suppresses postischemic inflammation and prevents acute renal failure. J Immunol (2010) 1.02
p53-independent roles of MDM2 in NF-κB signaling: implications for cancer therapy, wound healing, and autoimmune diseases. Neoplasia (2012) 1.01
A novel pathogenetic concept-antiviral immunity in lupus nephritis. Nat Rev Nephrol (2012) 1.01
Endogenous and exogenous pentraxin-3 limits postischemic acute and chronic kidney injury. Kidney Int (2013) 1.00
Double-stranded DNA activates glomerular endothelial cells and enhances albumin permeability via a toll-like receptor-independent cytosolic DNA recognition pathway. Am J Pathol (2009) 1.00
Viral 5'-triphosphate RNA and non-CpG DNA aggravate autoimmunity and lupus nephritis via distinct TLR-independent immune responses. Eur J Immunol (2008) 1.00
Anti-Ccl2 Spiegelmer permits 75% dose reduction of cyclophosphamide to control diffuse proliferative lupus nephritis and pneumonitis in MRL-Fas(lpr) mice. J Pharmacol Exp Ther (2008) 0.99
Targeting the recruitment of monocytes and macrophages in renal disease. Semin Nephrol (2010) 0.99
Mdm2 promotes systemic lupus erythematosus and lupus nephritis. J Am Soc Nephrol (2011) 0.99
Tissues use resident dendritic cells and macrophages to maintain homeostasis and to regain homeostasis upon tissue injury: the immunoregulatory role of changing tissue environments. Mediators Inflamm (2012) 0.96
Coactivation of Toll-like receptor-3 and -7 in immune complex glomerulonephritis. J Autoimmun (2007) 0.96
Lack of SIGIRR/TIR8 aggravates hydrocarbon oil-induced lupus nephritis. J Pathol (2010) 0.96
Plasma leakage through glomerular basement membrane ruptures triggers the proliferation of parietal epithelial cells and crescent formation in non-inflammatory glomerular injury. J Pathol (2012) 0.95
Glomerular parietal epithelial cells in kidney physiology, pathology, and repair. Curr Opin Nephrol Hypertens (2013) 0.95
Chemokines in lupus nephritis. Front Biosci (2008) 0.95
Viral RNA induces type I interferon-dependent cytokine release and cell death in mesangial cells via melanoma-differentiation-associated gene-5: Implications for viral infection-associated glomerulonephritis. Am J Pathol (2009) 0.95
Trif is not required for immune complex glomerulonephritis: dying cells activate mesangial cells via Tlr2/Myd88 rather than Tlr3/Trif. Am J Physiol Renal Physiol (2009) 0.94
Toll-like receptor signaling and SIGIRR in renal fibrosis upon unilateral ureteral obstruction. PLoS One (2011) 0.94
Bacterial CpG-DNA accelerates Alport glomerulosclerosis by inducing an M1 macrophage phenotype and tumor necrosis factor-α-mediated podocyte loss. Kidney Int (2010) 0.94
New insights into the pathology of podocyte loss: mitotic catastrophe. Am J Pathol (2013) 0.94
Polyene macrolide antifungal drugs trigger interleukin-1β secretion by activating the NLRP3 inflammasome. PLoS One (2011) 0.93
The antiviral cytokines IFN-α and IFN-β modulate parietal epithelial cells and promote podocyte loss: implications for IFN toxicity, viral glomerulonephritis, and glomerular regeneration. Am J Pathol (2013) 0.92
Tumour necrosis factor-α drives Alport glomerulosclerosis in mice by promoting podocyte apoptosis. J Pathol (2011) 0.92
Quantitative expression of C-type lectin receptors in humans and mice. Int J Mol Sci (2012) 0.91
The danger control concept in kidney disease: mesangial cells. J Nephrol (2013) 0.91
Lupus nephritis: update on mechanisms of systemic autoimmunity and kidney immunopathology. Curr Opin Nephrol Hypertens (2014) 0.91
Podocyte loss involves MDM2-driven mitotic catastrophe. J Pathol (2013) 0.91
Lack of the long pentraxin PTX3 promotes autoimmune lung disease but not glomerulonephritis in murine systemic lupus erythematosus. PLoS One (2011) 0.90
Interleukin-1 receptor-associated kinase-M suppresses systemic lupus erythematosus. Ann Rheum Dis (2011) 0.89
4SC-101, a novel small molecule dihydroorotate dehydrogenase inhibitor, suppresses systemic lupus erythematosus in MRL-(Fas)lpr mice. Am J Pathol (2010) 0.88
Renal failure increases cardiac histone h3 acetylation, dimethylation, and phosphorylation and the induction of cardiomyopathy-related genes in type 2 diabetes. Am J Pathol (2010) 0.88
Ccl2/Mcp-1 blockade reduces glomerular and interstitial macrophages but does not ameliorate renal pathology in collagen4A3-deficient mice with autosomal recessive Alport nephropathy. J Pathol (2009) 0.87
IRF4 deficiency abrogates lupus nephritis despite enhancing systemic cytokine production. J Am Soc Nephrol (2011) 0.87
Chemokines and chemokine receptors as therapeutic targets in lupus nephritis. Semin Nephrol (2007) 0.87
Double-stranded RNA activates type I interferon secretion in glomerular endothelial cells via retinoic acid-inducible gene (RIG)-1. Nephrol Dial Transplant (2009) 0.87
Recombinant chaperonin 10 suppresses cutaneous lupus and lupus nephritis in MRL-(Fas)lpr mice. Nephrol Dial Transplant (2011) 0.86
Toll-like receptor and accessory molecule mRNA expression in humans and mice as well as in murine autoimmunity, transient inflammation, and progressive fibrosis. Int J Mol Sci (2013) 0.86
Chemokine receptor CCR1: a new target for progressive kidney disease. Am J Nephrol (2005) 0.85
Evidence of new risk genetic factor to systemic lupus erythematosus: the UBASH3A gene. PLoS One (2013) 0.84
Postischemic vascular permeability requires both TLR-2 and TLR-4, but only TLR-2 mediates the transendothelial migration of leukocytes. Shock (2009) 0.83
What can tubular progenitor cultures teach us about kidney regeneration? Kidney Int (2013) 0.83
Interstitial inflammation in Alport syndrome. Hum Pathol (2009) 0.83
Kidney disease in lupus is not always 'lupus nephritis'. Arthritis Res Ther (2013) 0.82
Danger control programs cause tissue injury and remodeling. Int J Mol Sci (2013) 0.82
Activated protein C attenuates systemic lupus erythematosus and lupus nephritis in MRL-Fas(lpr) mice. J Immunol (2011) 0.82
Innate versus adaptive immunity in kidney immunopathology. BMC Nephrol (2013) 0.82
Pattern-recognition receptor signaling regulator mRNA expression in humans and mice, and in transient inflammation or progressive fibrosis. Int J Mol Sci (2013) 0.81
Efficient renal recruitment of macrophages and T cells in mice lacking the duffy antigen/receptor for chemokines. Am J Pathol (2009) 0.81
Pentraxins in nephrology: C-reactive protein, serum amyloid P and pentraxin-3. Nephrol Dial Transplant (2012) 0.81
Lupus nephritis: from pathogenesis to targets for biologic treatment. Nephron Clin Pract (2014) 0.81