What is the clinical benefit of preoperative chemoradiotherapy with 5FU/leucovorin for T3-4 rectal cancer in a pooled analysis of EORTC 22921 and FFCD 9203 trials: surrogacy in question?

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🔗 View Article (PMID 22507892)

Published in Eur J Cancer on April 14, 2012

Authors

F Bonnetain1, J F Bosset, J P Gerard, G Calais, T Conroy, L Mineur, O Bouché, P Maingon, O Chapet, L Radosevic-Jelic, N Methy, L Collette

Author Affiliations

1: Biostatistics and Epidemiology Department, EA 4184 Centre Georges François Leclerc & FFCD, Dijon, France. fbonnetain@cgfl.fr

Associated clinical trials:

Radiation Therapy, Surgery, and Chemotherapy in Treating Patients With Rectal Cancer That Can Be Surgically Removed | NCT00002523

Radiation Therapy With or Without Chemotherapy Before Surgery in Treating Patients With Stage II or Stage III Rectal Cancer | NCT00296608

Preoperative Chemoradiotherapy With CApecitabine and Temozolomide in MGMT Silenced, MSS, Locally Advanced RecTal Cancer (CATARTIC) | NCT05136326

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