Published in J Mol Med (Berl) on April 21, 2012
The age-related changes in cartilage and osteoarthritis. Biomed Res Int (2013) 1.04
PBMC and exosome-derived Hotair is a critical regulator and potent marker for rheumatoid arthritis. Clin Exp Med (2014) 0.95
MicroRNAs in cartilage development, homeostasis, and disease. Curr Osteoporos Rep (2014) 0.89
Transcriptome analysis of ageing in uninjured human Achilles tendon. Arthritis Res Ther (2015) 0.88
Reduced MiR-675 in exosome in H19 RNA-related melanogenesis via MITF as a direct target. J Invest Dermatol (2013) 0.87
Could lncRNAs be the missing links in control of mesenchymal stem cell differentiation? J Cell Physiol (2015) 0.85
Quantitative allele-specific expression and DNA methylation analysis of H19, IGF2 and IGF2R in the human placenta across gestation reveals H19 imprinting plasticity. PLoS One (2012) 0.83
Imprinted and X-linked non-coding RNAs as potential regulators of human placental function. Epigenetics (2013) 0.82
miR-675-5p enhances tumorigenesis and metastasis of esophageal squamous cell carcinoma by targeting REPS2. Oncotarget (2016) 0.81
MicroRNA-411 inhibited matrix metalloproteinase 13 expression in human chondrocytes. Am J Transl Res (2015) 0.79
-----Insulin-Like Growth Factor II (IGF-II) Inhibits IL-1β-Induced Cartilage Matrix Loss and Promotes Cartilage Integrity in Experimental Osteoarthritis. J Cell Biochem (2015) 0.79
The Role of MicroRNAs and Their Targets in Osteoarthritis. Curr Rheumatol Rep (2016) 0.79
Long Non-coding RNAs and Their Roles in Non-small-cell Lung Cancer. Genomics Proteomics Bioinformatics (2016) 0.78
Significance of epigenetic landscape in cartilage regeneration from the cartilage development and pathology perspective. Stem Cells Dev (2014) 0.78
Differentially expressed microRNAs in chondrocytes from distinct regions of developing human cartilage. PLoS One (2013) 0.78
Global molecular changes in a tibial compression induced ACL rupture model of post-traumatic osteoarthritis. J Orthop Res (2016) 0.77
Review: Long Noncoding RNAs in the Regulation of Inflammatory Pathways in Rheumatoid Arthritis and Osteoarthritis. Arthritis Rheumatol (2016) 0.76
Expression of intronic miRNAs and their host gene Igf2 in a murine unilateral ureteral obstruction model. Braz J Med Biol Res (2015) 0.75
A novel regulatory network among LncRpa, CircRar1, MiR-671 and apoptotic genes promotes lead-induced neuronal cell apoptosis. Arch Toxicol (2016) 0.75
H19 gene methylation status is associated with male infertility. Exp Ther Med (2016) 0.75
Osteoarthritis in the Knee Joints of Göttingen Minipigs after Resection of the Anterior Cruciate Ligament? Missing Correlation of MRI, Gene and Protein Expression with Histological Scoring. PLoS One (2016) 0.75
Differential expression of TGF-β superfamily members and role of Smad1/5/9-signalling in chondral versus endochondral chondrocyte differentiation. Sci Rep (2016) 0.75
Emerging roles for long noncoding RNAs in skeletal biology and disease. Connect Tissue Res (2016) 0.75
Transcriptional profiling identifies differential expression of long non-coding RNAs in Jo-1 associated and inclusion body myositis. Sci Rep (2017) 0.75
Premature induction of hypertrophy during in vitro chondrogenesis of human mesenchymal stem cells correlates with calcification and vascular invasion after ectopic transplantation in SCID mice. Arthritis Rheum (2006) 4.16
Cartilage-like gene expression in differentiated human stem cell spheroids: a comparison of bone marrow-derived and adipose tissue-derived stromal cells. Arthritis Rheum (2003) 1.84
Induction of intervertebral disc-like cells from adult mesenchymal stem cells. Stem Cells (2005) 1.80
Reduced chondrogenic potential of adipose tissue derived stromal cells correlates with an altered TGFbeta receptor and BMP profile and is overcome by BMP-6. J Cell Physiol (2007) 1.79
Comparison of mesenchymal stem cells from bone marrow and adipose tissue for bone regeneration in a critical size defect of the sheep tibia and the influence of platelet-rich plasma. Biomaterials (2010) 1.58
Vascular endothelial growth factor gene-activated matrix (VEGF165-GAM) enhances osteogenesis and angiogenesis in large segmental bone defects. J Bone Miner Res (2005) 1.57
Calcification or dedifferentiation: requirement to lock mesenchymal stem cells in a desired differentiation stage. J Cell Physiol (2009) 1.42
The use of mesenchymal stem cells for chondrogenesis. Injury (2008) 1.38
New in vivo animal model to create intervertebral disc degeneration and to investigate the effects of therapeutic strategies to stimulate disc regeneration. Spine (Phila Pa 1976) (2002) 1.34
Porosity and pore size of beta-tricalcium phosphate scaffold can influence protein production and osteogenic differentiation of human mesenchymal stem cells: an in vitro and in vivo study. Acta Biomater (2008) 1.34
Enhanced expression of the human chitinase 3-like 2 gene (YKL-39) but not chitinase 3-like 1 gene (YKL-40) in osteoarthritic cartilage. Biochem Biophys Res Commun (2002) 1.27
Septal and lateral wall localization of PBP5, the major D,D-carboxypeptidase of Escherichia coli, requires substrate recognition and membrane attachment. Mol Microbiol (2010) 1.25
Autologous chondrocyte implantation using the original periosteum-cover technique versus matrix-associated autologous chondrocyte implantation: a randomized clinical trial. Am J Sports Med (2009) 1.19
Telomere length and telomerase activity during expansion and differentiation of human mesenchymal stem cells and chondrocytes. J Mol Med (Berl) (2003) 1.18
Ectopic bone formation associated with mesenchymal stem cells in a resorbable calcium deficient hydroxyapatite carrier. Biomaterials (2005) 1.17
Osteoarthritis: cellular and molecular changes in degenerating cartilage. Prog Histochem Cytochem (2006) 1.17
Platelet-rich plasma improves expansion of human mesenchymal stem cells and retains differentiation capacity and in vivo bone formation in calcium phosphate ceramics. Platelets (2006) 1.14
Chondrogenesis of mesenchymal stem cells: role of tissue source and inducing factors. Stem Cell Res Ther (2010) 1.14
Adenovirus-mediated gene transfer of growth and differentiation factor-5 into tenocytes and the healing rat Achilles tendon. Connect Tissue Res (2005) 1.13
Stimulation of gene expression and loss of anular architecture caused by experimental disc degeneration--an in vivo animal study. Spine (Phila Pa 1976) (2005) 1.11
Early and stable upregulation of collagen type II, collagen type I and YKL40 expression levels in cartilage during early experimental osteoarthritis occurs independent of joint location and histological grading. Arthritis Res Ther (2004) 1.09
Reduced reactivation from dormancy but maintained lineage choice of human mesenchymal stem cells with donor age. PLoS One (2011) 1.08
Chondrogenesis of mesenchymal stem cells in gel-like biomaterials in vitro and in vivo. Front Biosci (2008) 1.07
Release of active and depot GDF-5 after adenovirus-mediated overexpression stimulates rabbit and human intervertebral disc cells. J Mol Med (Berl) (2003) 1.07
Mesenchymal stem cell differentiation in an experimental cartilage defect: restriction of hypertrophy to bone-close neocartilage. Stem Cells Dev (2009) 1.05
The short stature homeodomain protein SHOX induces cellular growth arrest and apoptosis and is expressed in human growth plate chondrocytes. J Biol Chem (2004) 1.05
Correlation of COL10A1 induction during chondrogenesis of mesenchymal stem cells with demethylation of two CpG sites in the COL10A1 promoter. Arthritis Rheum (2008) 1.04
An in vivo study of a growth-factor enhanced, cell free, two-layered collagen-tricalcium phosphate in deep osteochondral defects. Biomaterials (2006) 1.04
Replicative aging of human articular chondrocytes during ex vivo expansion. Arthritis Rheum (2002) 1.03
Disc distraction shows evidence of regenerative potential in degenerated intervertebral discs as evaluated by protein expression, magnetic resonance imaging, and messenger ribonucleic acid expression analysis. Spine (Phila Pa 1976) (2006) 1.02
Chondrogenic pre-induction of human mesenchymal stem cells on beta-TCP: enhanced bone quality by endochondral heterotopic bone formation. Acta Biomater (2010) 1.02
Chondrogenesis of human mesenchymal stem cells by local transforming growth factor-beta delivery in a biphasic resorbable carrier. Tissue Eng Part A (2010) 0.98
Changes in gene expression and protein distribution at different stages of mechanically induced disc degeneration--an in vivo study on the New Zealand white rabbit. J Orthop Res (2006) 0.98
Sensitivity of notochordal disc cells to mechanical loading: an experimental animal study. Eur Spine J (2009) 0.98
A new porcine in vivo animal model of disc degeneration: response of anulus fibrosus cells, chondrocyte-like nucleus pulposus cells, and notochordal nucleus pulposus cells to partial nucleotomy. Spine (Phila Pa 1976) (2009) 0.97
Stiff-person syndromes: motor cortex hyperexcitability correlates with anti-GAD autoimmunity. Neurology (2004) 0.96
Influence of platelet-rich plasma on osteogenic differentiation of mesenchymal stem cells and ectopic bone formation in calcium phosphate ceramics. Cells Tissues Organs (2006) 0.95
Proliferation as a requirement for in vitro chondrogenesis of human mesenchymal stem cells. Stem Cells Dev (2012) 0.94
Tissue distribution of a human Ca v 1.2 alpha1 subunit splice variant with a 75 bp insertion. Cell Calcium (2005) 0.94
Molecular analysis of expansion, differentiation, and growth factor treatment of human chondrocytes identifies differentiation markers and growth-related genes. Biochem Biophys Res Commun (2002) 0.94
Chondrocyte secreted CRTAC1: a glycosylated extracellular matrix molecule of human articular cartilage. Matrix Biol (2006) 0.94
Occurrence and regional distribution of apoptosis in scoliotic discs. Spine (Phila Pa 1976) (2005) 0.93
The course of high-sensitive C-reactive protein in correlation with pain and clinical function in patients with acute lumbosciatic pain and chronic low back pain - a 6 months prospective longitudinal study. Eur J Pain (2006) 0.93
Rapid regulation of collagen but not metalloproteinase 1, 3, 13, 14 and tissue inhibitor of metalloproteinase 1, 2, 3 expression in response to mechanical loading of cartilage explants in vitro. Arch Biochem Biophys (2003) 0.93
Methods to monitor distribution and metabolic activity of mesenchymal stem cells following in vivo injection into nucleotomized porcine intervertebral discs. Eur Spine J (2009) 0.93
Enhanced early tissue regeneration after matrix-assisted autologous mesenchymal stem cell transplantation in full thickness chondral defects in a minipig model. Cell Transplant (2009) 0.92
Correlation of hypoxic signalling to histological grade and outcome in cartilage tumours. Histopathology (2010) 0.89
Different culture media affect growth characteristics, surface marker distribution and chondrogenic differentiation of human bone marrow-derived mesenchymal stromal cells. BMC Musculoskelet Disord (2013) 0.89
Enhanced ITM2A expression inhibits chondrogenic differentiation of mesenchymal stem cells. Differentiation (2009) 0.89
The collagen component of biological bone graft substitutes promotes ectopic bone formation by human mesenchymal stem cells. Acta Biomater (2013) 0.88
Secretion of matrix metalloproteinase 3 by expanded articular chondrocytes as a predictor of ectopic cartilage formation capacity in vivo. Arthritis Rheum (2008) 0.88
Accelerated intervertebral disc degeneration in scoliosis versus physiological ageing develops against a background of enhanced anabolic gene expression. Biochem Biophys Res Commun (2006) 0.87
Highly sensitive and selective measurement of underivatized methylmalonic acid in serum and plasma by liquid chromatography-tandem mass spectrometry. Anal Bioanal Chem (2012) 0.87
Matrix metalloprotease inhibitors suppress initiation and progression of chondrogenic differentiation of mesenchymal stromal cells in vitro. Stem Cells Dev (2009) 0.86
CD4⁺CD25⁺/highCD127low/⁻ regulatory T cells are enriched in rheumatoid arthritis and osteoarthritis joints--analysis of frequency and phenotype in synovial membrane, synovial fluid and peripheral blood. Arthritis Res Ther (2014) 0.85
BMP and TGFbeta pathways in human central chondrosarcoma: enhanced endoglin and Smad 1 signaling in high grade tumors. BMC Cancer (2012) 0.84
OA in 2011: Age-related OA--a concept emerging from infancy? Nat Rev Rheumatol (2012) 0.84
Enhanced reconstruction of long bone architecture by a growth factor mutant combining positive features of GDF-5 and BMP-2. Biomaterials (2013) 0.83
Discrimination between cells of murine and human origin in xenotransplants by species specific genomic in situ hybridization. Xenotransplantation (2010) 0.83
Matrix-assisted cell transfer for intervertebral disc cell therapy. Biochem Biophys Res Commun (2005) 0.83
Intermittent PTHrP(1-34) exposure augments chondrogenesis and reduces hypertrophy of mesenchymal stromal cells. Stem Cells Dev (2014) 0.82
Interplay between local versus soluble transforming growth factor-beta and fibrin scaffolds: role of cells and impact on human mesenchymal stem cell chondrogenesis. Tissue Eng Part A (2012) 0.81
Engineering hydrophobin DewA to generate surfaces that enhance adhesion of human but not bacterial cells. Acta Biomater (2011) 0.81
Influence of depression symptoms on serum tumor necrosis factor-α of patients with chronic low back pain. Arthritis Res Ther (2010) 0.81
Enhanced biochemical and biomechanical properties of scaffolds generated by flock technology for cartilage tissue engineering. Tissue Eng Part A (2010) 0.80
Long-term mechanical loading of chondrocyte-chitosan biocomposites in vitro enhanced their proteoglycan and collagen content. Biorheology (2006) 0.80
Stiff-man syndrome: identification of 17 beta-hydroxysteroid dehydrogenase type 4 as a novel 80-kDa antineuronal antigen. J Neuroimmunol (2002) 0.80
Molecular characterization of spontaneous and growth-factor-augmented chondrogenesis in periosteum-bone tissue transferred into a joint. Histochem Cell Biol (2005) 0.79
Local application of a collagen type I/hyaluronate matrix and growth and differentiation factor 5 influences the closure of osteochondral defects in a minipig model by enchondral ossification. Growth Factors (2006) 0.78
cis-9,trans-11 and trans-10,cis-12 CLA affect lipid metabolism differently in primary white and brown adipocytes of Djungarian hamsters. Lipids (2003) 0.78
The effect of two point mutations in GDF-5 on ectopic bone formation in a beta-tricalciumphosphate scaffold. Biomaterials (2010) 0.78
Xenogeneic transplantation of articular chondrocytes into full-thickness articular cartilage defects in minipigs: fate of cells and the role of macrophages. Cell Tissue Res (2014) 0.77
Design and characterization of a rotating bed system bioreactor for tissue engineering applications. Biotechnol Prog (2008) 0.77
A rotating bed system bioreactor enables cultivation of primary osteoblasts on well-characterized Sponceram regarding structural and flow properties. Biotechnol Prog (2010) 0.77
The impact of pain spread on the outcome of multidisciplinary therapy in patients with chronic musculoskeletal pain - a prospective clinical study in 389 patients. Eur J Pain (2010) 0.77
No effect of subperiosteal growth factor application on periosteal neo-chondrogenesis in osteoperiosteal bone grafts for osteochondral defect repair. Int Orthop (2013) 0.76
Complete subchondral bone defect regeneration with a tricalcium phosphate collagen implant and osteoinductive growth factors: a randomized controlled study in Göttingen minipigs. J Biomed Mater Res B Appl Biomater (2013) 0.75
Quantitative measurement of plasma free metanephrines by ion-pairing solid phase extraction and liquid chromatography-tandem mass spectrometry with porous graphitic carbon column. J Chromatogr B Analyt Technol Biomed Life Sci (2011) 0.75
Effects of local application of growth and differentiation factor-5 (GDF-5) in a full-thickness cartilage defect model. Growth Factors (2004) 0.75
A study on the influence of biocompatible composites with bioactive ligands toward their effect on cell adhesion and growth for the application in bone tissue engineering. J Biomed Mater Res B Appl Biomater (2009) 0.75
A simple and robust LC-MS/MS method for measuring sirolimus and everolimus in whole blood. Bioanalysis (2014) 0.75
Is Total Disk Replacement a Cost-effective Treatment for Cervical Degenerative Disk Disease? Clin Spine Surg (2017) 0.75
Detection of apoptotic cartilage cells in symptomatic central tears of the triangular fibrocartilage. J Hand Surg Am (2007) 0.75
Multicenter evaluation of the thermo scientific prelude for measurement of immunosuppressant drugs using sample preparation liquid chromatography-tandem mass spectrometry. Ther Drug Monit (2015) 0.75
Regulating chondrogenesis of human mesenchymal stromal cells with a retinoic Acid receptor-Beta inhibitor: differential sensitivity of chondral versus osteochondral development. Cell Physiol Biochem (2014) 0.75