Published in Eur J Immunol on May 01, 2012
Sustained effector function of IL-12/15/18-preactivated NK cells against established tumors. J Exp Med (2012) 1.86
Robust Anti-viral Immunity Requires Multiple Distinct T Cell-Dendritic Cell Interactions. Cell (2015) 1.28
Aptamer-targeted inhibition of mTOR in T cells enhances antitumor immunity. J Clin Invest (2014) 1.22
Revealing the role of CD4(+) T cells in viral immunity. J Exp Med (2012) 1.17
FoxO1 controls effector-to-memory transition and maintenance of functional CD8 T cell memory. J Immunol (2013) 1.09
T cell exhaustion during persistent viral infections. Virology (2015) 1.00
T-cell therapies for HIV. Immunotherapy (2013) 0.99
Cellular and population plasticity of helper CD4(+) T cell responses. Front Physiol (2013) 0.96
Cerebrospinal fluid (CSF) CD8+ T-cells that express interferon-gamma contribute to HIV associated neurocognitive disorders (HAND). PLoS One (2015) 0.94
Competition for antigen between Th1 and Th2 responses determines the timing of the immune response switch during Mycobaterium avium subspecies paratuberulosis infection in ruminants. PLoS Comput Biol (2014) 0.91
The multifaceted role of CD4(+) T cells in CD8(+) T cell memory. Nat Rev Immunol (2016) 0.90
T-Bet and Eomes Regulate the Balance between the Effector/Central Memory T Cells versus Memory Stem Like T Cells. PLoS One (2013) 0.90
Therapeutic Vaccine Strategies against Human Papillomavirus. Vaccines (Basel) (2014) 0.89
CD8 T cell tolerance to a tumor-associated self-antigen is reversed by CD4 T cells engineered to express the same T cell receptor. J Immunol (2014) 0.88
Longitudinal requirement for CD4+ T cell help for adenovirus vector-elicited CD8+ T cell responses. J Immunol (2014) 0.87
Vitamin D receptor expression controls proliferation of naïve CD8+ T cells and development of CD8 mediated gastrointestinal inflammation. BMC Immunol (2014) 0.86
Oncolytic virus-mediated reversal of impaired tumor antigen presentation. Front Oncol (2014) 0.85
CD4+ T cell help is dispensable for protective CD8+ T cell memory against mousepox virus following vaccinia virus immunization. J Virol (2014) 0.85
Hantaan virus infection induces both Th1 and ThGranzyme B+ cell immune responses that associated with viral control and clinical outcome in humans. PLoS Pathog (2015) 0.82
CD4+ T-cell help is required for effective CD8+ T cell-mediated resolution of acute viral hepatitis in mice. PLoS One (2014) 0.82
Early IFN-gamma production after YF 17D vaccine virus immunization in mice and its association with adaptive immune responses. PLoS One (2013) 0.82
Lipidoid Nanoparticles Containing PD-L1 siRNA Delivered In Vivo Enter Kupffer Cells and Enhance NK and CD8(+) T Cell-mediated Hepatic Antiviral Immunity. Mol Ther Nucleic Acids (2013) 0.82
Expansion of Inefficient HIV-Specific CD8 T Cells during Acute Infection. J Virol (2016) 0.81
Influenza T-cell epitope-loaded virosomes adjuvanted with CpG as a potential influenza vaccine. Pharm Res (2014) 0.81
Regulatory CD8+ T cells associated with erosion of immune surveillance in persistent virus infection suppress in vitro and have a reversible proliferative defect. J Immunol (2013) 0.79
Orchestration of CD4 T cell epitope preferences after multipeptide immunization. J Immunol (2013) 0.78
Induction of WT1-specific human CD8+ T cells from human HSCs in HLA class I Tg NOD/SCID/IL2rgKO mice. Blood (2015) 0.77
CD4 T cell responses in latent and chronic viral infections. Front Immunol (2013) 0.77
Immediate Dysfunction of Vaccine-Elicited CD8+ T Cells Primed in the Absence of CD4+ T Cells. J Immunol (2016) 0.77
Strategic Priming with Multiple Antigens can Yield Memory Cell Phenotypes Optimized for Infection with Mycobacterium tuberculosis: A Computational Study. Front Microbiol (2016) 0.76
Blimp-1-mediated CD4 T cell exhaustion causes CD8 T cell dysfunction during chronic toxoplasmosis. J Exp Med (2016) 0.75
B-Cell-Deficient and CD8 T-Cell-Depleted Gnotobiotic Pigs for the Study of Human Rotavirus Vaccine-Induced Protective Immune Responses. Viral Immunol (2016) 0.75
T-cell therapies for HIV: Preclinical successes and current clinical strategies. Cytotherapy (2016) 0.75
Peracetic Acid Treatment Generates Potent Inactivated Oral Vaccines from a Broad Range of Culturable Bacterial Species. Front Immunol (2016) 0.75
Rapid Functional Decline of Activated and Memory Graft-versus-Host-Reactive T Cells Encountering Host Antigens in the Absence of Inflammation. J Immunol (2015) 0.75
CD4(+) T-cell dependence of primary CD8(+) T-cell response against vaccinia virus depends upon route of infection and viral dose. Cell Mol Immunol (2014) 0.75
CD8+ T cell immunity in an encephalitis model of Toxoplasma gondii infection. Semin Immunopathol (2015) 0.75
Effect of entinostat on NK cell-mediated cytotoxicity against osteosarcoma cells and osteosarcoma lung metastasis. Oncoimmunology (2017) 0.75
Co-delivery of the NKT agonist α-galactosylceramide and tumor antigens to cross-priming dendritic cells breaks tolerance to self-antigens and promotes antitumor responses. Oncoimmunology (2017) 0.75
HIV preferentially infects HIV-specific CD4+ T cells. Nature (2002) 9.28
Delay of HIV-1 rebound after cessation of antiretroviral therapy through passive transfer of human neutralizing antibodies. Nat Med (2005) 5.68
IL-21R on T cells is critical for sustained functionality and control of chronic viral infection. Science (2009) 3.90
Disseminated and sustained HIV infection in CD34+ cord blood cell-transplanted Rag2-/-gamma c-/- mice. Proc Natl Acad Sci U S A (2006) 3.07
Memory inflation: continuous accumulation of antiviral CD8+ T cells over time. J Immunol (2003) 3.02
Functional properties and lineage relationship of CD8+ T cell subsets identified by expression of IL-7 receptor alpha and CD62L. J Immunol (2005) 2.80
Immediate cytotoxicity but not degranulation distinguishes effector and memory subsets of CD8+ T cells. J Exp Med (2004) 2.59
Quantifiable cytotoxic T lymphocyte responses and HLA-related risk of progression to AIDS. Proc Natl Acad Sci U S A (2004) 1.97
Differential role of IL-2R signaling for CD8+ T cell responses in acute and chronic viral infections. Eur J Immunol (2007) 1.92
Emergence of polyfunctional CD8+ T cells after prolonged suppression of human immunodeficiency virus replication by antiretroviral therapy. J Virol (2008) 1.79
Recall proliferation potential of memory CD8+ T cells and antiviral protection. J Immunol (2005) 1.73
Entry and transcription as key determinants of differences in CD4 T-cell permissiveness to human immunodeficiency virus type 1 infection. J Virol (2004) 1.68
Failure to detect xenotropic murine leukemia virus-related virus in blood of individuals at high risk of blood-borne viral infections. J Infect Dis (2010) 1.62
Nonhematopoietic cells are key players in innate control of bacterial airway infection. J Immunol (2011) 1.61
Expansion of protective CD8+ T-cell responses driven by recombinant cytomegaloviruses. J Virol (2004) 1.55
Long-lived memory CD8+ T cells are programmed by prolonged antigen exposure and low levels of cellular activation. Eur J Immunol (2006) 1.52
Impaired NFAT nuclear translocation results in split exhaustion of virus-specific CD8+ T cell functions during chronic viral infection. Proc Natl Acad Sci U S A (2007) 1.51
A prospective trial of structured treatment interruptions in human immunodeficiency virus infection. Arch Intern Med (2003) 1.44
Inflammasome activation and IL-1β target IL-1α for secretion as opposed to surface expression. Proc Natl Acad Sci U S A (2011) 1.33
Interleukin 2: from immunostimulation to immunoregulation and back again. EMBO Rep (2007) 1.31
MyD88-dependent IFN-gamma production by NK cells is key for control of Legionella pneumophila infection. J Immunol (2006) 1.29
Programmed death 1 protects from fatal circulatory failure during systemic virus infection of mice. J Exp Med (2012) 1.29
A novel role for neutrophils as critical activators of NK cells. J Immunol (2008) 1.22
Cutting edge: distinct roles for T help and CD40/CD40 ligand in regulating differentiation of proliferation-competent memory CD8+ T cells. J Immunol (2004) 1.21
Systemic antibody responses to gut commensal bacteria during chronic HIV-1 infection. Gut (2011) 1.18
A novel Th cell epitope of Candida albicans mediates protection from fungal infection. J Immunol (2012) 1.17
Antigen-dependent and -independent mechanisms of T and B cell hyperactivation during chronic HIV-1 infection. J Virol (2011) 1.17
Non-hematopoietic cells in lymph nodes drive memory CD8 T cell inflation during murine cytomegalovirus infection. PLoS Pathog (2011) 1.17
HIV-1-specific CD4+ T lymphocyte turnover and activation increase upon viral rebound. J Clin Invest (2005) 1.15
On the role of the inhibitory receptor LAG-3 in acute and chronic LCMV infection. Int Immunol (2009) 1.15
Humoral immunity to HIV-1: kinetics of antibody responses in chronic infection reflects capacity of immune system to improve viral set point. Blood (2004) 1.14
Immune senescence: relative contributions of age and cytomegalovirus infection. PLoS Pathog (2012) 1.13
Batf3 transcription factor-dependent DC subsets in murine CMV infection: differential impact on T-cell priming and memory inflation. Eur J Immunol (2011) 1.12
Peroxiredoxin 6 is required for blood vessel integrity in wounded skin. J Cell Biol (2007) 1.12
How chronic viral infections impact on antigen-specific T-cell responses. Eur J Immunol (2010) 1.12
NK cells regulating T cell responses: mechanisms and outcome. Trends Immunol (2015) 1.09
Antibodies protect against intracellular bacteria by Fc receptor-mediated lysosomal targeting. Proc Natl Acad Sci U S A (2010) 1.07
O Mannosylation of alpha-dystroglycan is essential for lymphocytic choriomeningitis virus receptor function. J Virol (2005) 1.06
Virus-specific CD8 T cells: activation, differentiation and memory formation. APMIS (2009) 1.05
Virological and immunological effects of short-course antiretroviral therapy in primary HIV infection. AIDS (2002) 1.05
IL-21 restricts virus-driven Treg cell expansion in chronic LCMV infection. PLoS Pathog (2013) 1.03
Type-I IFN drives the differentiation of short-lived effector CD8+ T cells in vivo. Eur J Immunol (2011) 1.03
The dynamics of mouse cytomegalovirus-specific CD4 T cell responses during acute and latent infection. J Immunol (2008) 1.03
Type I IFN substitutes for T cell help during viral infections. J Immunol (2010) 1.02
Th cells act via two synergistic pathways to promote antiviral CD8+ T cell responses. J Immunol (2010) 1.01
Direct activation of antigen-presenting cells is required for CD8+ T-cell priming and tumor vaccination. Proc Natl Acad Sci U S A (2011) 1.00
Absence of cross-presenting cells in the salivary gland and viral immune evasion confine cytomegalovirus immune control to effector CD4 T cells. PLoS Pathog (2011) 1.00
Antigen amount dictates CD8+ T-cell exhaustion during chronic viral infection irrespective of the type of antigen presenting cell. Eur J Immunol (2012) 1.00
Macrophage and T cell produced IL-10 promotes viral chronicity. PLoS Pathog (2013) 0.98
Differential survival of cytotoxic T cells and memory cell precursors. J Immunol (2007) 0.96
CD8+ T cells are activated in an antigen-independent manner in HIV-infected individuals. J Immunol (2014) 0.96
Relevance of HIV-1-specific CD4+ helper T-cell responses during structured treatment interruptions in patients with CD4+ T-cell nadir above 400/mm3. J Acquir Immune Defic Syndr (2004) 0.95
IL-10 suppression of NK/DC crosstalk leads to poor priming of MCMV-specific CD4 T cells and prolonged MCMV persistence. PLoS Pathog (2012) 0.94
Defective T helper response of hepatocyte-stimulated CD4 T cells impairs antiviral CD8 response and viral clearance. Gastroenterology (2007) 0.94
Discordant outcomes following failure of antiretroviral therapy are associated with substantial differences in human immunodeficiency virus-specific cellular immunity. J Virol (2003) 0.92
Comparing the kinetics of NK cells, CD4, and CD8 T cells in murine cytomegalovirus infection. J Immunol (2011) 0.91
T-cell help permits memory CD8(+) T-cell inflation during cytomegalovirus latency. Eur J Immunol (2011) 0.91
Kinetic and mechanistic requirements for helping CD8 T cells. J Immunol (2008) 0.91
Systemic antibody responses to gut microbes in health and disease. Gut Microbes (2012) 0.90
Comparison of cytotoxic T lymphocyte efficacy in acute and persistent lymphocytic choriomeningitis virus infection. Proc Biol Sci (2011) 0.89
HIV-1 replication activates CD4+ T cells with specificities for persistent herpes viruses. EMBO Mol Med (2010) 0.88
Novel CD8+ T cell antagonists based on beta 2-microglobulin. J Biol Chem (2002) 0.87
Functional and biophysical characterization of an HLA-A*6801-restricted HIV-specific T cell receptor. Eur J Immunol (2007) 0.87
Antibody-Fc receptor interactions in protection against intracellular pathogens. Eur J Immunol (2011) 0.87
Non-neutralizing antibodies protect from chronic LCMV infection independently of activating FcγR or complement. Eur J Immunol (2013) 0.86
Post-translational modification of {alpha}-dystroglycan is not critical for lymphocytic choriomeningitis virus receptor function in vivo. J Gen Virol (2008) 0.85
Superior induction and maintenance of protective CD8 T cells in mice infected with mouse cytomegalovirus vector expressing RAE-1γ. Proc Natl Acad Sci U S A (2013) 0.85
Induction and protective role of antibodies in Legionella pneumophila infection. Eur J Immunol (2007) 0.85
Adoptive transfer of cytomegalovirus-specific effector CD4+ T cells provides antiviral protection from murine CMV infection. Eur J Immunol (2013) 0.85
A controlled trial of granulocyte macrophage-colony stimulating factor during interruption of HAART. AIDS (2003) 0.85
VSV-GP: a potent viral vaccine vector that boosts the immune response upon repeated applications. J Virol (2014) 0.83
The risks of targeting co-inhibitory pathways to modulate pathogen-directed T cell responses. Trends Immunol (2013) 0.83
Reversal of chronic to resolved infection by IL-10 blockade is LCMV strain dependent. Eur J Immunol (2013) 0.82
HIV replication elicits little cytopathic effects in vivo: analysis of surrogate markers for virus production, cytotoxic T cell response and infected cell death. J Med Virol (2006) 0.82
Impact of antigen specificity on CD4+ T cell activation in chronic HIV-1 infection. BMC Infect Dis (2013) 0.81
T cell memory in the context of persistent herpes viral infections. Viruses (2012) 0.80
T-cell help dependence of memory CD8+ T-cell expansion upon vaccinia virus challenge relies on CD40 signaling. Eur J Immunol (2013) 0.80
Innate instruction of CD4+ T cell immunity in respiratory bacterial infection. J Immunol (2012) 0.79
No evidence for competition between cytotoxic T-lymphocyte responses in HIV-1 infection. Proc Biol Sci (2009) 0.79
T lymphocyte responses against human parvovirus B19: small virus, big response. Pathol Biol (Paris) (2002) 0.78
CD4 T cell responses in latent and chronic viral infections. Front Immunol (2013) 0.77
Salivary gland resident APCs are Flt3L- and CCR2-independent macrophage-like cells incapable of cross-presentation. Eur J Immunol (2013) 0.77
Identification of protective B cell antigens of Legionella pneumophila. J Immunol (2012) 0.77
Assessment of legionella-specific immunity in mice. Methods Mol Biol (2013) 0.75
Immunofluorescence imaging of legionella infection in vitro. Methods Mol Biol (2013) 0.75