Neuroprotection of early and short-time applying berberine in the acute phase of cerebral ischemia: up-regulated pAkt, pGSK and pCREB, down-regulated NF-κB expression, ameliorated BBB permeability.

PubWeight™: 0.95‹?› | Rank: Top 15%

🔗 View Article (PMID 22560097)

Published in Brain Res on April 04, 2012

Authors

Xiaolin Zhang1, Xiangjian Zhang, Chaohui Wang, Yanhua Li, Lipeng Dong, Lili Cui, Lina Wang, Zongjie Liu, Huimin Qiao, Chunhua Zhu, Yinxue Xing, Xiaoyun Cao, Ye Ji, Kang Zhao

Author Affiliations

1: Department of Neurology, Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, 050000, China.

Articles citing this

Berberine protects against neuronal damage via suppression of glia-mediated inflammation in traumatic brain injury. PLoS One (2014) 0.85

Berberine exerts an anticonvulsant effect and ameliorates memory impairment and oxidative stress in a pilocarpine-induced epilepsy model in the rat. Neuropsychiatr Dis Treat (2014) 0.84

One-Compound-Multi-Target: Combination Prospect of Natural Compounds with Thrombolytic Therapy in Acute Ischemic Stroke. Curr Neuropharmacol (2017) 0.84

Therapeutic Effect of Berberine on Huntington's Disease Transgenic Mouse Model. PLoS One (2015) 0.79

Protection of Gastrointestinal Mucosa from Acute Heavy Alcohol Consumption: The Effect of Berberine and Its Correlation with TLR2, 4/IL1β-TNFα Signaling. PLoS One (2015) 0.79

An effective solution to discover synergistic drugs for anti-cerebral ischemia from traditional Chinese medicinal formulae. PLoS One (2013) 0.79

Progesterone alleviates hypoxic-ischemic brain injury via the Akt/GSK-3β signaling pathway. Exp Ther Med (2014) 0.78

Neuroprotective effect of interleukin-6 in a rat model of cerebral ischemia. Exp Ther Med (2015) 0.78

Berberine protects against 6-OHDA-induced neurotoxicity in PC12 cells and zebrafish through hormetic mechanisms involving PI3K/AKT/Bcl-2 and Nrf2/HO-1 pathways. Redox Biol (2016) 0.75

Role of berberine in Alzheimer's disease. Neuropsychiatr Dis Treat (2016) 0.75

Neuroprotective and Anti-Apoptotic Effects of CSP-1103 in Primary Cortical Neurons Exposed to Oxygen and Glucose Deprivation. Int J Mol Sci (2017) 0.75

Therapeutic effect of berberine on TDP-43-related pathogenesis in FTLD and ALS. J Biomed Sci (2016) 0.75

Effect of progesterone intervention on the dynamic changes of AQP-4 in hypoxic-ischaemic brain damage. Int J Clin Exp Med (2015) 0.75

Diabetes Worsens Ischemia-Reperfusion Brain Injury in Rats Through GSK-3β. Am J Med Sci (2015) 0.75

Treatment of acute cerebral ischemia using animal models: a meta-analysis. Transl Neurosci (2015) 0.75

Articles by these authors

Lethally hot temperatures during the Early Triassic greenhouse. Science (2012) 5.28

Synthesis of N-substituted indole derivatives via PIFA-mediated intramolecular cyclization. Org Lett (2006) 3.37

Cancer survival in China, 2003-2005: a population-based study. Int J Cancer (2014) 3.32

Physics. Learning and scientific reasoning. Science (2009) 2.49

Generation of induced pluripotent stem cells from urine. J Am Soc Nephrol (2011) 2.36

Syphilis among female sex workers in southwestern China: potential for HIV transmission. Sex Transm Dis (2006) 2.34

Glaucoma-like optic neuropathy in patients with intracranial tumours. Acta Ophthalmol (2011) 2.08

Two novel adeno-associated viruses from cynomolgus monkey: pseudotyping characterization of capsid protein. Virology (2004) 1.88

The 30-amino-acid deletion in the Nsp2 of highly pathogenic porcine reproductive and respiratory syndrome virus emerging in China is not related to its virulence. J Virol (2009) 1.77

Generation of human induced pluripotent stem cells from urine samples. Nat Protoc (2012) 1.76

Activation of peroxisome proliferator-activated receptor-γ coactivator 1α ameliorates mitochondrial dysfunction and protects podocytes from aldosterone-induced injury. Kidney Int (2012) 1.75

Brain edema after intracerebral hemorrhage in rats: the role of inflammation. Neurol India (2006) 1.69

Salicylic acid based small molecule inhibitor for the oncogenic Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2). J Med Chem (2010) 1.63

SOX2 gene regulates the transcriptional network of oncogenes and affects tumorigenesis of human lung cancer cells. PLoS One (2012) 1.55

The MTA family proteins as novel histone H3 binding proteins. Cell Biosci (2013) 1.52

Small molecule Me6TREN mobilizes hematopoietic stem/progenitor cells by activating MMP-9 expression and disrupting SDF-1/CXCR4 axis. Blood (2013) 1.49

Curcumin upregulates transcription factor Nrf2, HO-1 expression and protects rat brains against focal ischemia. Brain Res (2009) 1.49

SDF-1 promotes endochondral bone repair during fracture healing at the traumatic brain injury condition. PLoS One (2013) 1.47

Retracted Triptolide ameliorates lipopolysaccharide-induced acute lung injury in rats. Eur J Med Res (2013) 1.43

No TRAP, no invasion. Trends Parasitol (2008) 1.41

Maternal separation produces lasting changes in cortisol and behavior in rhesus monkeys. Proc Natl Acad Sci U S A (2011) 1.31

Arithmetic processing in the brain shaped by cultures. Proc Natl Acad Sci U S A (2006) 1.31

High prevalence of myopia and high myopia in 5060 Chinese university students in Shanghai. Invest Ophthalmol Vis Sci (2012) 1.28

Methylation of SUV39H1 by SET7/9 results in heterochromatin relaxation and genome instability. Proc Natl Acad Sci U S A (2013) 1.24

Efficient -2 frameshifting by mammalian ribosomes to synthesize an additional arterivirus protein. Proc Natl Acad Sci U S A (2012) 1.22

The sequential processing of visual feature conjunction mismatches in the human brain. Psychophysiology (2004) 1.20

Methyltransferase Set7/9 regulates p53 activity by interacting with Sirtuin 1 (SIRT1). Proc Natl Acad Sci U S A (2011) 1.17

Data-driven robust approximate optimal tracking control for unknown general nonlinear systems using adaptive dynamic programming method. IEEE Trans Neural Netw (2011) 1.17

Taste masking microspheres for orally disintegrating tablets. Int J Pharm (2008) 1.15

Determinants of arterial wall remodeling during lipid-lowering therapy: serial intravascular ultrasound observations from the Reversal of Atherosclerosis with Aggressive Lipid Lowering Therapy (REVERSAL) trial. Circulation (2006) 1.14

Tumor-like stem cells derived from human keloid are governed by the inflammatory niche driven by IL-17/IL-6 axis. PLoS One (2009) 1.12

Apical location of a novel EGF-like domain-containing protein of Plasmodium falciparum. Mol Biochem Parasitol (2003) 1.11

Development of nanomaterials for bone repair and regeneration. J Biomed Mater Res B Appl Biomater (2012) 1.11

Time trends in oral clefts in Chinese newborns: data from the Chinese National Birth Defects Monitoring Network. Birth Defects Res A Clin Mol Teratol (2010) 1.10

Formation of N-alkoxyindole framework: intramolecular heterocyclization of 3-alkoxyimino-2-arylalkylnitriles mediated by ferric chloride. J Org Chem (2008) 1.08

Generation of induced pluripotent stem cell lines from 3 distinct laminopathies bearing heterogeneous mutations in lamin A/C. Aging (Albany NY) (2011) 1.08

Nonstructural protein 2 of porcine reproductive and respiratory syndrome virus inhibits the antiviral function of interferon-stimulated gene 15. J Virol (2012) 1.07

FOXO3 induces FOXO1-dependent autophagy by activating the AKT1 signaling pathway. Autophagy (2012) 1.05

SOX2 regulates apoptosis through MAP4K4-survivin signaling pathway in human lung cancer cells. Carcinogenesis (2013) 1.05

Oxymatrine downregulates TLR4, TLR2, MyD88, and NF-kappaB and protects rat brains against focal ischemia. Mediators Inflamm (2010) 1.04

Limitations of encapsidation of recombinant self-complementary adeno-associated viral genomes in different serotype capsids and their quantitation. Hum Gene Ther Methods (2012) 1.04

Can tamsulosin facilitate expulsion of ureteral stones? A meta-analysis of randomized controlled trials. Int J Urol (2012) 1.03

Variant alleles of TGFB1 and TGFBR2 are associated with a decreased risk of gastric cancer in a Chinese population. Int J Cancer (2007) 1.02

Genome wide transcriptional profile analysis of Vitis amurensis and Vitis vinifera in response to cold stress. PLoS One (2013) 1.01

Vpr14-88-Apobec3G fusion protein is efficiently incorporated into Vif-positive HIV-1 particles and inhibits viral infection. PLoS One (2008) 1.01

Targeting the shift from M1 to M2 macrophages in experimental autoimmune encephalomyelitis mice treated with fasudil. PLoS One (2013) 1.01

The β2-adrenergic receptor and Her2 comprise a positive feedback loop in human breast cancer cells. Breast Cancer Res Treat (2010) 1.01

Modeling abnormal early development with induced pluripotent stem cells from aneuploid syndromes. Hum Mol Genet (2011) 1.00

Discovery of retroviral homologs in bats: implications for the origin of mammalian gammaretroviruses. J Virol (2012) 1.00

Discovery and evaluation of novel inhibitors of mycobacterium protein tyrosine phosphatase B from the 6-Hydroxy-benzofuran-5-carboxylic acid scaffold. J Med Chem (2013) 1.00

Mitochondrial dysfunction accounts for aldosterone-induced epithelial-to-mesenchymal transition of renal proximal tubular epithelial cells. Free Radic Biol Med (2012) 1.00

Event-related potentials evoked by multi-feature conflict under different attentive conditions. Exp Brain Res (2002) 0.99

Hypoxia-induced HIF-1 alpha accumulation is augmented in a co-culture of keloid fibroblasts and human mast cells: involvement of ERK1/2 and PI-3K/Akt. Exp Cell Res (2005) 0.98

Cathepsin D is secreted from M-BE cells: its potential role as a biomarker of lung cancer. J Proteome Res (2007) 0.98

SHP2 is a target of the immunosuppressant tautomycetin. Chem Biol (2011) 0.98

XBP-1u suppresses autophagy by promoting the degradation of FoxO1 in cancer cells. Cell Res (2013) 0.98

Structural and mechanistic insights into LEOPARD syndrome-associated SHP2 mutations. J Biol Chem (2013) 0.97

High density lipoprotein (HDL) promotes glucose uptake in adipocytes and glycogen synthesis in muscle cells. PLoS One (2011) 0.97

An improved method of sample preparation on AnchorChip targets for MALDI-MS and MS/MS and its application in the liver proteome project. Proteomics (2007) 0.96

Overexpression of SPINDLIN1 induces cellular senescence, multinucleation and apoptosis. Gene (2007) 0.96

Atorvastatin protects rat brains against permanent focal ischemia and downregulates HMGB1, HMGB1 receptors (RAGE and TLR4), NF-kappaB expression. Neurosci Lett (2010) 0.96

Theory, experiment, and application of optical fiber etching. Appl Opt (2012) 0.96

A rhodium(I)-catalyzed demethylation-cyclization of o-anisole-substituted ynamides in the synthesis of chiral 2-amido benzofurans. Org Lett (2007) 0.96

Green tea extract and (-)-epigallocatechin-3-gallate inhibit mast cell-stimulated type I collagen expression in keloid fibroblasts via blocking PI-3K/AkT signaling pathways. J Invest Dermatol (2006) 0.96

Development of a fluorescent microsphere immunoassay for detection of antibodies against porcine reproductive and respiratory syndrome virus using oral fluid samples as an alternative to serum-based assays. Clin Vaccine Immunol (2011) 0.95

Baicalein is neuroprotective in rat MCAO model: role of 12/15-lipoxygenase, mitogen-activated protein kinase and cytosolic phospholipase A2. Pharmacol Biochem Behav (2010) 0.95

Tanshinone II A down-regulates HMGB1, RAGE, TLR4, NF-kappaB expression, ameliorates BBB permeability and endothelial cell function, and protects rat brains against focal ischemia. Brain Res (2010) 0.95

Understanding topics and sentiment in an online cancer survivor community. J Natl Cancer Inst Monogr (2013) 0.94

Inhibitory antibodies specific for the 19-kilodalton fragment of merozoite surface protein 1 do not correlate with delayed appearance of infection with Plasmodium falciparum in semi-immune individuals in Vietnam. Infect Immun (2009) 0.94

Polymorphisms of miRNAs genes are associated with the risk and prognosis of coronary artery disease. Clin Res Cardiol (2011) 0.94

Genome-wide identification of WRKY family genes and their response to cold stress in Vitis vinifera. BMC Plant Biol (2014) 0.94

Ursolic acid promotes the neuroprotection by activating Nrf2 pathway after cerebral ischemia in mice. Brain Res (2012) 0.94

TCTP promotes glioma cell proliferation in vitro and in vivo via enhanced β-catenin/TCF-4 transcription. Neuro Oncol (2013) 0.93

Exogenous hydrogen sulfide prevents cardiomyocyte apoptosis from cardiac hypertrophy induced by isoproterenol. Mol Cell Biochem (2013) 0.93

MicroRNA array and microarray evaluation of endometrial receptivity in patients with high serum progesterone levels on the day of hCG administration. Reprod Biol Endocrinol (2011) 0.93

High-performance rechargeable lithium-iodine batteries using triiodide/iodide redox couples in an aqueous cathode. Nat Commun (2013) 0.93

Synthesis of alpha-keto-imides via oxidation of ynamides. J Org Chem (2008) 0.93

Age-related changes in tissue macrophages precede cardiac functional impairment. Aging (Albany NY) (2014) 0.93

Synthesis of oxazoles from enamides via phenyliodine diacetate-mediated intramolecular oxidative cyclization. J Org Chem (2012) 0.92

An Efficient Route to beta-D-Isoxazolidinyl Nucleosides via Diastereoselective Michael Addition of Hydroxylamine to Unsaturated Esters. J Org Chem (1997) 0.92

Tibia tumor-induced cancer pain involves spinal p38 mitogen-activated protein kinase activation via TLR4-dependent mechanisms. Brain Res (2010) 0.92

The protection by octreotide against experimental ischemic stroke: up-regulated transcription factor Nrf2, HO-1 and down-regulated NF-κB expression. Brain Res (2012) 0.92

Salvianolic Acid B Attenuates Rat Hepatic Fibrosis via Downregulating Angiotensin II Signaling. Evid Based Complement Alternat Med (2012) 0.92

Luteolin downregulates TLR4, TLR5, NF-κB and p-p38MAPK expression, upregulates the p-ERK expression, and protects rat brains against focal ischemia. Brain Res (2012) 0.92