Use of crossover trials to obtain antihypertensive dose-response curves and to study combination therapy during the development of benazepril.

PubWeight™: 0.76‹?›

🔗 View Article (PMID 2258783)

Published in J Hypertens Suppl on September 01, 1990

Authors

M Bellet1, J J Whalen, F Bodin, D Serrurier, K Tanner, J Ménard

Author Affiliations

1: Ciba-Geigy Ltd, Basle, Switzerland.

Articles by these authors

(truncated to the top 100)

Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial. HOT Study Group. Lancet (1998) 26.64

Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: a randomised placebo-controlled study. Lancet (2001) 6.88

Premature discontinuation of clinical trial for reasons not related to efficacy, safety, or feasibility. BMJ (2001) 2.74

Converting enzyme inhibition and kidney function in normotensive diabetic patients with persistent microalbuminuria. Br Med J (Clin Res Ed) (1987) 2.67

Acute angiotensin-converting enzyme inhibition increases the plasma level of the natural stem cell regulator N-acetyl-seryl-aspartyl-lysyl-proline. J Clin Invest (1996) 2.20

[Recurrence of unipolar depression and efficacy of maprotiline]. Encephale (1990) 2.04

The 1993 guidelines for the management of mild hypertension: memorandum from a WHO/ISH meeting. Blood Press (1993) 2.03

High plasma level of N-acetyl-seryl-aspartyl-lysyl-proline: a new marker of chronic angiotensin-converting enzyme inhibition. Hypertension (1997) 1.71

Paraoxonase 1 (PON1) gene variants are not associated with clopidogrel response. Clin Pharmacol Ther (2011) 1.69

Home self blood pressure measurement in general practice. The SMART study. Self-measurement for the Assessment of the Response to Trandolapril. Am J Hypertens (1996) 1.66

[Characteristics of smokers seeking smoking cessation services: the CDT programme]. Rev Mal Respir (2005) 1.47

Effectiveness of oral diclofenac in the acute treatment of common migraine attacks: a double-blind study versus placebo. Cephalalgia (1991) 1.40

Additive effects of combined angiotensin-converting enzyme inhibition and angiotensin II antagonism on blood pressure and renin release in sodium-depleted normotensives. Circulation (1995) 1.38

Vascular damage without hypertension in transgenic rats expressing prorenin exclusively in the liver. J Clin Invest (1996) 1.32

Mild hypertension: the mysterious viability of a faulty concept. J Hypertens (1995) 1.31

Reproducibility of the 6-minute walk test in obese adults. Int J Sports Med (2009) 1.28

Determinants of angiotensin II generation during converting enzyme inhibition. Hypertension (1990) 1.23

[Screening for phaeochromocytoma : in which hypertensive patients? A semiological study of 2585 patients, including 11 with phaeochromocytoma (author's transl)]. Nouv Presse Med (1981) 1.22

Dietary sources and correlates of sodium and potassium intakes in the French general population. Eur J Clin Nutr (2009) 1.18

Angiotensinogen: an attractive and underrated participant in hypertension and inflammation. Hypertension (1991) 1.16

Distribution of Salmonella in swine herds in Québec. Vet Microbiol (1999) 1.16

Angiotensinogen concentrations and renin clearance : implications for blood pressure regulation. Hypertension (2000) 1.12

Cardiovascular abnormalities with normal blood pressure in tissue kallikrein-deficient mice. Proc Natl Acad Sci U S A (2001) 1.11

A micromethod for measurement of renin in the plasma and kidney of rats. Can J Physiol Pharmacol (1967) 1.07

Ligase-free subcloning: a versatile method to subclone polymerase chain reaction (PCR) products in a single day. Anal Biochem (1991) 1.06

Cardiac weight in hypertension induced by nitric oxide synthase blockade. Hypertension (1993) 1.05

The international database of self-recorded blood pressures in normotensive and untreated hypertensive subjects. Blood Press Monit (1999) 1.03

High human renin hypertension in transgenic rats. Hypertension (1997) 1.00

RNA template-specific PCR: an improved method that dramatically reduces false positives in RT-PCR. Biotechniques (1991) 1.00

Pharmacokinetics and erythropoietic response to human recombinant erythropoietin in healthy men. Clin Pharmacol Ther (1990) 0.99

Computer-assisted techniques for evaluation and treatment of hypertensive patients. Am J Hypertens (1990) 0.99

Campylobacter enteritis in British Columbia--a 30 month study. Can J Public Health (1986) 0.97

Local angiotensin II generation in the rat heart: role of renin uptake. Circ Res (1998) 0.94

Mendelian randomization supports causality between maternal hyperglycemia and epigenetic regulation of leptin gene in newborns. Epigenetics (2015) 0.94

Atypical mycobacterial disease in British Columbia, 1960-1967. Can Med Assoc J (1969) 0.94

Decision to treat mild hypertension after assessment by ambulatory monitoring and World Health Organisation recommendations. BMJ (1992) 0.94

Calcium blockade versus ACE inhibition in clipped and unclipped kidneys of 2K-1C rats. Kidney Int (1994) 0.94

M235T variant of the human angiotensinogen gene in unselected hypertensive patients. J Hypertens Suppl (1993) 0.93

Transrectal high-intensity focused ultrasound (HIFU) treatment of localized prostate cancer: review of technical incidents and morbidity after 5 years of use. Prostate Cancer Prostatic Dis (2010) 0.92

Valsartan, a new angiotensin II antagonist for the treatment of essential hypertension: a comparative study of the efficacy and safety against amlodipine. Clin Pharmacol Ther (1996) 0.92

Survival after a first episode of spontaneous bacterial peritonitis. Prognosis of potential candidates for orthotopic liver transplantation. J Gastroenterol Hepatol (1995) 0.91

Vascular angiotensin-converting enzyme expression regulates local angiotensin II. Hypertension (1997) 0.91

Angiotensin-converting enzyme gene polymorphism has no influence on the circulating renin-angiotensin-aldosterone system or blood pressure in normotensive subjects. Circulation (1995) 0.91

[Tienilic acid-induced hepatitis associated with liver/kidney microsomal antibody (author's transl)]. Nouv Presse Med (1980) 0.89

Bradykinin pathway is involved in acute hemodynamic effects of enalaprilat in dogs with heart failure. Am J Physiol (1996) 0.88

Mechanical sensitization of cutaneous C-fiber nociceptors by prostaglandin E2 in the rat. Neurosci Lett (1999) 0.88

Identity of angiotensinogen precursors of rat brain and liver. Nature (1984) 0.88

Amoxicillin-clavulanic acid therapy of spontaneous bacterial peritonitis: a prospective study of twenty-seven cases in cirrhotic patients. Hepatology (1990) 0.88

Additive effects of losartan and enalapril on blood pressure and plasma active renin. Hypertension (1997) 0.87

Studies on the contact sensitization of man with simple chemicals. III. Quantitative relationships between specific lymphocyte transformation, skin sensitivity, and lymphokine activity in response to dinitrochlorobenzene. J Invest Dermatol (1975) 0.87

Treating the individual hypertensive patient: considerations on dose, sequential monotherapy and drug combinations. J Hypertens (1990) 0.86

Active immunization against renin in normotensive marmoset. Proc Natl Acad Sci U S A (1987) 0.86

The absolute risk as a guide to influence the treatment decision-making process in mild hypertension. J Hypertens (1997) 0.86

Effects of estrogens on renin substrate and uterine weights in rats. Endocrinology (1973) 0.86

Valsartan, a new angiotensin II antagonist for the treatment of essential hypertension: efficacy and safety compared with placebo and enalapril. J Hypertens (1996) 0.86

Immunologic approaches to blockade of the renin-angiotensin system: a review. Am Heart J (1989) 0.86

Valsartan: long-term efficacy and tolerability compared to lisinopril in elderly patients with essential hypertension. Clin Exp Hypertens (1997) 0.86

Mouse and rat plasma renin concentration and gene expression in (mRen2)27 transgenic rats. Am J Physiol (1998) 0.85

Effects of the dual endothelin receptor antagonist bosentan in patients with pulmonary hypertension: a placebo-controlled study. J Heart Lung Transplant (2001) 0.85

Molecular scanning for mutations in the insulin receptor substrate-1 (IRS-1) gene in Mexican Americans with Type 2 diabetes mellitus. Diabetes Metab Res Rev (2000) 0.85

[Poland's syndrome in women: Therapeutic indications according to the grade. Apropos of 11 cases and review of the literature]. Ann Chir Plast Esthet (2011) 0.85

Prevalence, treatment, and control of hypertension in the French population: data from a survey on high blood pressure in general practice, 1994. Am J Hypertens (1998) 0.84

[Endoscopic aspects and results of controlled biopsy in 165 cases of stomach cancer]. Arch Fr Mal App Dig (1972) 0.84

Pharmacodynamic effects of dual neutral endopeptidase-angiotensin-converting enzyme inhibition versus angiotensin-converting enzyme inhibition in humans. Clin Pharmacol Ther (1999) 0.84

[Detection, diagnosis and localization of pheochromocytoma. 77 cases in a population of 21,420 hypertensive patients]. Presse Med (1987) 0.84

Hemodynamic and biochemical consequences of renin inhibition by infusion of CGP 38560A in normal volunteers. Hypertension (1989) 0.83

Plasma angiotensins, renin, and blood pressure during acute renin inhibition by CGP 38 560A in hypertensive patients. Am J Hypertens (1989) 0.83

Contrasting effects of selective T- and L-type calcium channel blockade on glomerular damage in DOCA hypertensive rats. Hypertension (1999) 0.83

[Upper gastrointestinal haemorrhage in the patients aged over 65 years. The contribution of endoscopy (author's transl)]. Nouv Presse Med (1979) 0.83

Direct radioimmunoassay and immunocytochemical localization of renin in human kidneys. Clin Sci (Lond) (1979) 0.83

Letter: Sperm-induced lymphocyte transformation. Lancet (1974) 0.83

A study of the renin inhibitor H142 in man. J Hypertens (1985) 0.83

Effect of bradykinin and kininogens in isolated rat kidney vasoconstricted by angiotensin II. Am J Physiol (1990) 0.83

Valsartan, a new angiotensin II antagonist for the treatment of essential hypertension: efficacy and safety compared to hydrochlorothiazide. Eur J Clin Pharmacol (1997) 0.82

Enalaprilat: an intravenous substitute for oral enalapril therapy. Humoral and pharmacokinetic effects. J Clin Hypertens (1986) 0.82

Vascular effects and metabolism of angiotensins and their metabolites in the isolated perfused rat kidney. Clin Exp Hypertens A (1983) 0.82

Pilot study of combined blockade of the renin-angiotensin system in essential hypertensive patients. J Hypertens (2000) 0.82

Renal and metabolic clearance of N-acetyl-seryl-aspartyl-lysyl-proline (AcSDKP) during angiotensin-converting enzyme inhibition in humans. Hypertension (1999) 0.82

Influence of sodium diet on L-NAME effects on renin release and renal vasoconstriction. Am J Physiol (1994) 0.82

Testosterone replacement treatment options for HIV-infected men. J Acquir Immune Defic Syndr Hum Retrovirol (1997) 0.82

Seven lessons from seven renin secreting tumors. Kidney Int Suppl (1988) 0.82

Systemic hypertension after cardiac transplantation: effect of cyclosporine on the renin-angiotensin-aldosterone system. Am J Cardiol (1985) 0.82

Immunocytochemical localization of renin in juxtaglomerular cells. J Histochem Cytochem (1985) 0.82

Mixed cultures of sperm and leukocytes as a measure of histcompatibility in man. Science (1976) 0.82

[Campylobacter pylori, gastritis and ulcer disease. Microbiological, histological and serological studies]. Schweiz Med Wochenschr (1988) 0.82

Biochemical similarity of partially purified inactive renins from human plasma and kidney. Hypertension (1982) 0.82

Developmental studies demonstrate age-dependent elevation of renin activity in TGR(mRen2)27 rats. Am J Hypertens (1995) 0.82

Open rhinoplasty: influence of incisions, alar resection, and columellar strut on final appearance of the tip. Aesthetic Plast Surg (2014) 0.82

Long-term metabolic effects of spironolactone and thiazides combined with potassium-sparing agents for treatment of essential hypertension. Am J Cardiol (1988) 0.81

[Cyclic idiopathic edema syndrome. I. Clinical study]. J Urol Nephrol (Paris) (1971) 0.81

[Demonstration of differences in the effect of 2 antihypertensive agents by self blood pressure measurement: comparison of trandolapril and perindopril]. Therapie (1997) 0.81

[Decentralization of the ARTEMIS system in a nephrology service in a general hospital]. Arch Mal Coeur Vaiss (1987) 0.81

Studies on the contact sensitization of man with simple chemicals. IV. Timing of skin reactivity, lymphokine production, and blastogenesis following rechallenge with dinitrochlorobenzene using an automated microassay. J Invest Dermatol (1975) 0.81

Assessment of drug efficacy using home self-blood pressure measurement: the SMART study. Self Measurement for the Assessment of the Response to Trandolapril. J Hum Hypertens (1996) 0.81

High plasma aldosterone and low renin predict blood pressure increase and hypertension in middle-aged Caucasian populations. J Hum Hypertens (2008) 0.80

Need for plasma angiotensin measurements to investigate converting-enzyme inhibition in humans. Am Heart J (1989) 0.80

Human renin-dependent hypertension in rats transgenic for human angiotensinogen. Hypertension (1996) 0.80

Antialdosterones: incidence and prevention of sexual side effects. J Steroid Biochem (1989) 0.80

[Validation of Oscillomat, a device for self-measurement of blood pressure. Comparison with mercury sphygmomanometers]. Presse Med (1991) 0.80

Body fluid spaces and blood pressure in hemodialysis patients during amelioration of anemia with erythropoietin. Am J Kidney Dis (1990) 0.80