Published in Food Addit Contam on January 01, 1990
Premature discontinuation of clinical trial for reasons not related to efficacy, safety, or feasibility. BMJ (2001) 2.74
The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence. Pharmacogenetics (1997) 2.55
Diet, antioxidant status, and smoking habits in French men. Am J Clin Nutr (1998) 2.41
A multilocus genotyping assay for candidate markers of cardiovascular disease risk. Genome Res (1999) 2.13
Segregation analysis and variance components analysis of bone mineral density in healthy families. J Bone Miner Res (1995) 1.55
Association of the G-2548A polymorphism in the 5' region of the LEP gene with overweight. Ann Hum Genet (2000) 1.53
Pharmacogenomics education: International Society of Pharmacogenomics recommendations for medical, pharmaceutical, and health schools deans of education. Pharmacogenomics J (2005) 1.53
Biological variability of superoxide dismutase, glutathione peroxidase, and catalase in blood. Clin Chem (1991) 1.42
Aspartate aminotransferase and alanine aminotransferase activities in plasma: statistical distributions, individual variations, and reference values. Clin Chem (1975) 1.39
An insertion deletion polymorphism in the signal peptide of the human apolipoprotein B gene. Hum Genet (1990) 1.36
The UDP glucuronosyltransferase gene superfamily: suggested nomenclature based on evolutionary divergence. DNA Cell Biol (1991) 1.35
Interleukin-1beta down-regulates the expression of glucuronosyltransferase I, a key enzyme priming glycosaminoglycan biosynthesis: influence of glucosamine on interleukin-1beta-mediated effects in rat chondrocytes. Arthritis Rheum (2001) 1.35
Intima-media thickness and diameter of carotid and femoral arteries in children, adolescents and adults from the Stanislas cohort: effect of age, sex, anthropometry and blood pressure. J Hypertens (1998) 1.29
Determination of serum cystatin C: biological variation and reference values. Clin Chem Lab Med (2001) 1.26
gamma-Glutamyltransferase dependent generation of reactive oxygen species from a glutathione/transferrin system. Free Radic Biol Med (1998) 1.26
Decreased high-density lipoprotein cholesterol and serum apolipoprotein AI concentrations are highly correlated with the severity of Alzheimer's disease. Neurobiol Aging (2000) 1.24
Blood and plasma glutathione measured in healthy subjects by HPLC: relation to sex, aging, biological variables, and life habits. Clin Chem (1995) 1.24
Glucosamine modulates IL-1-induced activation of rat chondrocytes at a receptor level, and by inhibiting the NF-kappa B pathway. FEBS Lett (2002) 1.21
Allele frequency distribution of the (TG)n(AG)m microsatellite in the apolipoprotein C-II gene. Genomics (1992) 1.20
Total bone and liver alkaline phosphatases in plasma: biological variations and reference limits. Clin Chem (1983) 1.16
UDP-glucuronosyltransferase activities. Guidelines for consistent interim terminology and assay conditions. Biochem Pharmacol (1983) 1.14
Increased levels of apolipoprotein D in cerebrospinal fluid and hippocampus of Alzheimer's patients. J Neurochem (1998) 1.11
Apolipoprotein E serum concentration and polymorphism in six European countries: the ApoEurope Project. Atherosclerosis (2000) 1.06
Glucuronidation of drugs by hepatic microsomes derived from healthy and cirrhotic human livers. J Pharmacol Exp Ther (1999) 1.06
Stimulation of proteoglycan synthesis by glucuronosyltransferase-I gene delivery: a strategy to promote cartilage repair. Proc Natl Acad Sci U S A (2004) 1.05
Need for revisiting the concept of reference values. Clin Chem Lab Med (2000) 1.04
Subcellular distribution of cytochrome P-450 in the brain. Brain Res (1986) 1.04
Dietary intakes, eating style and overweight in the Stanislas Family Study. Int J Obes Relat Metab Disord (2000) 1.03
Human aminopeptidases: a review of the literature. J Clin Chem Clin Biochem (1988) 1.03
Wine, beer, and mortality in middle-aged men from eastern France. Arch Intern Med (1999) 1.03
Glucuronidation of hyodeoxycholic acid in human liver. Evidence for a selective role of UDP-glucuronosyltransferase 2B4. J Biol Chem (1993) 1.03
A multilocus genotyping assay for cardiovascular disease. Clin Chem Lab Med (1998) 1.01
Drug metabolizing enzymes in the brain and cerebral microvessels. Brain Res Brain Res Rev (1991) 1.01
Activation of the mouse TATA-less and human TATA-containing UDP-glucuronosyltransferase 1A1 promoters by hepatocyte nuclear factor 1. Mol Pharmacol (1999) 1.01
Multivariate genetic analysis of high density lipoprotein particles. Atherosclerosis (1992) 1.00
Subcellular localization of cytochrome P450, and activities of several enzymes responsible for drug metabolism in the human brain. Biochem Pharmacol (1993) 0.98
High sensitivity C-reactive protein: biological variations and reference limits. Clin Chem Lab Med (2000) 0.98
Localization of drug-metabolizing enzyme activities to blood-brain interfaces and circumventricular organs. J Neurochem (1994) 0.98
Genetics strongly determines the wall thickness of the left and right carotid arteries. Hum Genet (1998) 0.98
Increased protein glycation in cerebrospinal fluid of Alzheimer's disease. Neurobiol Aging (2001) 0.97
Serum myeloperoxidase concentration in a healthy population: biological variations, familial resemblance and new genetic polymorphisms. Eur J Hum Genet (2001) 0.97
Effect of alcohol consumption on blood antioxidant nutrients and oxidative stress indicators. Am J Clin Nutr (1994) 0.97
Expression of multiple gamma-glutamyltransferase genes in man. Biochem J (1994) 0.96
[Side effects of fenamates]. Therapie (1977) 0.96
An analysis of genotype effects and their interactions by using the apolipoprotein E polymorphism and longitudinal data. Am J Hum Genet (1989) 0.95
Blood activity of Cu/Zn superoxide dismutase, glutathione peroxidase and catalase in Alzheimer's disease: a case-control study. Gerontology (1990) 0.95
Metabolic determinants are much more important than genetic polymorphisms in determining the PAI-1 activity and antigen plasma concentrations: a family study with part of the Stanislas Cohort. Arterioscler Thromb Vasc Biol (1998) 0.94
Five-year alterations in BMI are associated with clustering of changes in cardiovascular risk factors in a gender-dependant way: the Stanislas study. Int J Obes (Lond) (2008) 0.94
Biological variations and genetic reference values for apolipoprotein E serum concentrations: results from the STANISLAS cohort study. Clin Chem (1998) 0.93
In vitro N-glucuronidation of a novel antiepileptic drug, lamotrigine, by human liver microsomes. J Pharmacol Exp Ther (1992) 0.92
Relations between reported alcohol consumption and certain biological variables in an "unselected" population. Clin Chem (1979) 0.92
Association of a functional 5-HT transporter gene polymorphism with anorexia nervosa and food intake. Mol Psychiatry (2001) 0.92
Conformation of apolipoprotein E both in free and in lipid-bound form may determine the avidity of triglyceride-rich lipoproteins to the LDL receptor: structural and kinetic study. Biochim Biophys Acta (2000) 0.91
Family study of lipoprotein lipase gene polymorphisms and plasma triglyceride levels. Genet Epidemiol (1996) 0.91
ELISA of 6-beta-hydroxycortisol in human urine: diurnal variations and effects of antiepileptic therapy. Clin Chim Acta (1986) 0.90
Structure/function of the human Ga1beta1,3-glucuronosyltransferase. Dimerization and functional activity are mediated by two crucial cysteine residues. J Biol Chem (2000) 0.90
Apolipoprotein E, transthyretin and actin in the CSF of Alzheimer's patients: relation with the senile plaques and cytoskeleton biochemistry. FEBS Lett (1998) 0.90
The chemical modification of human liver UDP-glucuronosyltransferase UGT1*6 reveals the involvement of a carboxyl group in catalysis. FEBS Lett (1994) 0.89
An improved method for phenotyping individuals for the human serum paraoxonase arylesterase polymorphism. Ann Biol Clin (Paris) (1986) 0.89
Gamma-glutamyltransferase: nucleotide sequence of the human pancreatic cDNA. Evidence for a ubiquitous gamma-glutamyltransferase polypeptide in human tissues. Biochem Pharmacol (1992) 0.89
Comparison of cytochrome P-450 content and activities in liver microsomes of seven animal species, including man. Xenobiotica (1986) 0.89
Effect of cigarette smoke on UDP-glucuronosyltransferase activity and cytochrome P450 content in liver, lung and kidney microsomes in mice. Pharmacol Toxicol (1998) 0.89
Reversal of hyperlipidaemia in apolipoprotein C1 transgenic mice by adenovirus-mediated gene delivery of the low-density-lipoprotein receptor, but not by the very-low-density-lipoprotein receptor. Biochem J (1999) 0.88
Apolipoprotein (apo) E genotype and apoE concentration determine binding of normal very low density lipoproteins to HepG2 cell surface receptors. J Lipid Res (1996) 0.88
Comparative effects of flavonoids and model inducers on drug-metabolizing enzymes in rat liver. Toxicology (1996) 0.88
Factors modulating the catalytic specificity of a pure form of UDP-glucuronyltransferase. J Biol Chem (1982) 0.88
Genetic Polymorphism of CYP2C19 gene in the Stanislas cohort. A link with inflammation. Ann Hum Genet (2008) 0.88
5-HT2A receptor gene polymorphism is associated with food and alcohol intake in obese people. Int J Obes Relat Metab Disord (2000) 0.88
Electrophoretic mobility, rosette formation and surface immunoglobulins of gradient fractionated human blood lymphocytes. Biomedicine (1974) 0.88
Glucuronidation of 3'-azido-3'-deoxythymidine in human liver microsomes: enzyme inhibition by drugs and steroid hormones. Biochim Biophys Acta (1992) 0.88
Importance of histidine residues for the function of the human liver UDP-glucuronosyltransferase UGT1A6: evidence for the catalytic role of histidine 370. Mol Pharmacol (2000) 0.87
Rat olfactory bulb and epithelium UDP-glucuronosyltransferase 2A1 (UGT2A1) expression: in situ mRNA localization and quantitative analysis. Brain Res Mol Brain Res (2001) 0.87
Soluble transferrin receptor (sTfR): biological variations and reference limits. Clin Chem Lab Med (2001) 0.87
Stable expression of two human UDP-glucuronosyltransferase cDNAs in V79 cell cultures. Mol Pharmacol (1991) 0.87
The human colonic microflora influences the alterations of xenobiotic-metabolizing enzymes by catechins in male F344 rats. Food Chem Toxicol (2003) 0.87
Genetic influences on lipid metabolism trait variability within the Stanislas Cohort. J Lipid Res (2001) 0.87
Frequencies of five genetic polymorphisms in coronarographed patients and effects on lipid levels in a supposedly healthy population. Clin Genet (1996) 0.86
Weights at birth and in early infancy, systolic pressure, and left ventricular structure in subjects aged 8 to 24 years. Hypertension (1996) 0.86
LEPR gene polymorphisms: associations with overweight, fat mass and response to diet in women. Eur J Clin Invest (2001) 0.86
An internal signal sequence mediates the targeting and retention of the human UDP-glucuronosyltransferase 1A6 to the endoplasmic reticulum. J Biol Chem (1999) 0.86
Total cholinesterase in plasma: biological variations and reference limits. Clin Chem (1985) 0.86
Biological variations in hyperlipidemic children and adolescents treated with fenofibrate. Clin Chim Acta (1981) 0.86
Induction of cytochrome P450 and/or detoxication enzymes by various extracts of rosemary: description of specific patterns. Food Chem Toxicol (2001) 0.86
Cerebrospinal fluid apolipoprotein E level is increased in late-onset Alzheimer's disease. J Neurol Sci (1997) 0.85
Arginine 52 and histidine 54 located in a conserved amino-terminal hydrophobic region (LX2-R52-G-H54-X3-V-L) are important amino acids for the functional and structural integrity of the human liver UDP-glucuronosyltransferase UGT1*6. Mol Pharmacol (1997) 0.85
A recombinant phenobarbital-inducible rat liver UDP-glucuronosyltransferase (UDP-glucuronosyltransferase 2B1) stably expressed in V79 cells catalyzes the glucuronidation of morphine, phenols, and carboxylic acids. Mol Pharmacol (1994) 0.85
Differential oxidation of apolipoprotein E isoforms and interaction with phospholipids. Free Radic Biol Med (2000) 0.85
Regioselective and stereospecific glucuronidation of trans- and cis-resveratrol in human. Arch Biochem Biophys (2001) 0.85
The glucuronosyltransferases: what progress can pharmacologists expect from molecular biology and cellular enzymology? Biochem Pharmacol (1987) 0.85
Albendazole sulfonation by rat liver cytochrome P-450c. J Pharmacol Exp Ther (1988) 0.85
Evidence for the pro-oxidant effect of gamma-glutamyltranspeptidase-related enzyme. Free Radic Biol Med (2000) 0.85
A novel UDP-Glc-specific glucosyltransferase catalyzing the biosynthesis of 6-O-glucosides of bile acids in human liver microsomes. J Biol Chem (1993) 0.85