Atsushi Enomoto

Author PubWeight™ 77.27‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Regulation of VEGF-mediated angiogenesis by the Akt/PKB substrate Girdin. Nat Cell Biol 2008 2.39
2 Clinical and molecular analysis of patients with renal hypouricemia in Japan-influence of URAT1 gene on urinary urate excretion. J Am Soc Nephrol 2004 1.87
3 An actin-binding protein Girdin regulates the motility of breast cancer cells. Cancer Res 2008 1.82
4 Up-regulation of DNA-dependent protein kinase activity and Sp1 in colorectal cancer. Int J Oncol 2004 1.42
5 The multivalent PDZ domain-containing protein PDZK1 regulates transport activity of renal urate-anion exchanger URAT1 via its C terminus. J Biol Chem 2004 1.40
6 Cell biology of the movement of breast cancer cells: intracellular signalling and the actin cytoskeleton. Cancer Lett 2009 1.40
7 Behavioral alterations associated with targeted disruption of exons 2 and 3 of the Disc1 gene in the mouse. Hum Mol Genet 2011 1.36
8 Interactions of human organic anion transporters with diuretics. J Pharmacol Exp Ther 2003 1.25
9 Indoxyl sulfate upregulates expression of ICAM-1 and MCP-1 by oxidative stress-induced NF-kappaB activation. Am J Nephrol 2010 1.22
10 Targeted mutation of serine 697 in the Ret tyrosine kinase causes migration defect of enteric neural crest cells. Development 2006 1.20
11 Indoxyl sulphate induces oxidative stress and the expression of osteoblast-specific proteins in vascular smooth muscle cells. Nephrol Dial Transplant 2009 1.14
12 Girding for migratory cues: roles of the Akt substrate Girdin in cancer progression and angiogenesis. Cancer Sci 2010 1.13
13 Function and localization of urate transporter 1 in mouse kidney. J Am Soc Nephrol 2004 1.11
14 Novel liver-specific organic anion transporter OAT7 that operates the exchange of sulfate conjugates for short chain fatty acid butyrate. Hepatology 2007 1.09
15 The human T-type amino acid transporter-1: characterization, gene organization, and chromosomal location. Genomics 2002 1.07
16 The actin-binding protein Girdin and its Akt-mediated phosphorylation regulate neointima formation after vascular injury. Circ Res 2011 1.06
17 Sprouty2 regulates growth and differentiation of human neuroblastoma cells through RET tyrosine kinase. Cancer Sci 2007 1.03
18 Girdin is an intrinsic regulator of neuroblast chain migration in the rostral migratory stream of the postnatal brain. J Neurosci 2011 1.02
19 NF-κB plays an important role in indoxyl sulfate-induced cellular senescence, fibrotic gene expression, and inhibition of proliferation in proximal tubular cells. Am J Physiol Cell Physiol 2011 1.02
20 Functional characterization of rat organic anion transporter 5 (Slc22a19) at the apical membrane of renal proximal tubules. J Pharmacol Exp Ther 2005 1.02
21 Characterization of the HDAC1 complex that regulates the sensitivity of cancer cells to oxidative stress. Cancer Res 2009 1.01
22 Indoxyl sulfate promotes vascular smooth muscle cell senescence with upregulation of p53, p21, and prelamin A through oxidative stress. Am J Physiol Cell Physiol 2012 1.00
23 Dok-4 regulates GDNF-dependent neurite outgrowth through downstream activation of Rap1 and mitogen-activated protein kinase. J Cell Sci 2006 1.00
24 Interactions of human organic anion transporters and human organic cation transporters with nonsteroidal anti-inflammatory drugs. J Pharmacol Exp Ther 2002 0.99
25 GDNF-mediated signaling via RET tyrosine 1062 is essential for maintenance of spermatogonial stem cells. Genes Cells 2008 0.99
26 RET receptor signaling: dysfunction in thyroid cancer and Hirschsprung's disease. Pathol Int 2006 0.98
27 Human organic anion transporters and human organic cation transporters mediate renal transport of prostaglandins. J Pharmacol Exp Ther 2002 0.98
28 Involvement of Girdin in the determination of cell polarity during cell migration. PLoS One 2012 0.98
29 NMDA receptor regulates migration of newly generated neurons in the adult hippocampus via Disrupted-In-Schizophrenia 1 (DISC1). J Neurochem 2011 0.97
30 CD109 expression in basal-like breast carcinoma. Pathol Int 2008 0.95
31 Indoxyl sulfate downregulates renal expression of Klotho through production of ROS and activation of nuclear factor-ĸB. Am J Nephrol 2011 0.95
32 Renal urate handling: clinical relevance of recent advances. Curr Rheumatol Rep 2005 0.95
33 Interaction of human and rat organic anion transporter 2 with various cephalosporin antibiotics. Eur J Pharmacol 2003 0.94
34 Interactions of urate transporter URAT1 in human kidney with uricosuric drugs. Nephrology (Carlton) 2011 0.93
35 Senescence and dysfunction of proximal tubular cells are associated with activated p53 expression by indoxyl sulfate. Am J Physiol Cell Physiol 2010 0.92
36 The REV7 subunit of DNA polymerase ζ is essential for primordial germ cell maintenance in the mouse. J Biol Chem 2013 0.92
37 Girdin locates in centrosome and midbody and plays an important role in cell division. Cancer Sci 2012 0.91
38 The Dishevelled-associating protein Daple controls the non-canonical Wnt/Rac pathway and cell motility. Nat Commun 2012 0.91
39 Girdin and its phosphorylation dynamically regulate neonatal vascular development and pathological neovascularization in the retina. Am J Pathol 2012 0.91
40 The W258X mutation in SLC22A12 is the predominant cause of Japanese renal hypouricemia. Pediatr Nephrol 2004 0.90
41 Interactions of human- and rat-organic anion transporters with pravastatin and cimetidine. J Pharmacol Sci 2004 0.89
42 Indoxyl sulfate-induced activation of (pro)renin receptor is involved in expression of TGF-β1 and α-smooth muscle actin in proximal tubular cells. Endocrinology 2014 0.88
43 Indoxyl sulfate promotes cardiac fibrosis with enhanced oxidative stress in hypertensive rats. Life Sci 2013 0.88
44 Indoxyl sulfate promotes proliferation of human aortic smooth muscle cells by inducing oxidative stress. J Ren Nutr 2009 0.88
45 Adiponectin promotes migration activities of endothelial progenitor cells via Cdc42/Rac1. FEBS Lett 2009 0.85
46 Src tyrosine kinase inhibitor PP2 suppresses ERK1/2 activation and epidermal growth factor receptor transactivation by X-irradiation. Biochem Biophys Res Commun 2006 0.85
47 A novel GDNF-inducible gene, BMZF3, encodes a transcriptional repressor associated with KAP-1. Biochem Biophys Res Commun 2007 0.85
48 Anti-tumor activity of olaparib, a poly (ADP-ribose) polymerase (PARP) inhibitor, in cultured endometrial carcinoma cells. BMC Cancer 2014 0.85
49 Sodium orthovanadate inhibits p53-mediated apoptosis. Cancer Res 2010 0.84
50 Similar phenotypes of Girdin germ-line and conditional knockout mice indicate a crucial role for Girdin in the nestin lineage. Biochem Biophys Res Commun 2012 0.84
51 Expression of Ret finger protein correlates with outcomes in endometrial cancer. Cancer Sci 2009 0.83
52 Identification of a novel organic anion transporter mediating carnitine transport in mouse liver and kidney. Cell Physiol Biochem 2010 0.83
53 Suppression of anchorage-independent growth by expression of the ataxia-telangiectasia group D complementing gene, ATDC. Biochem Biophys Res Commun 2006 0.83
54 Protective role of Gipie, a Girdin family protein, in endoplasmic reticulum stress responses in endothelial cells. Mol Biol Cell 2011 0.83
55 Accumulation of indoxyl sulfate in OAT1/3-positive tubular cells in kidneys of patients with chronic renal failure. J Ren Nutr 2006 0.83
56 Epidermal hyperplasia and appendage abnormalities in mice lacking CD109. Am J Pathol 2012 0.82
57 Free radical scavenger edaravone suppresses x-ray-induced apoptosis through p53 inhibition in MOLT-4 cells. J Radiat Res 2007 0.82
58 Radiosensitization by hyperthermia in the chicken B-lymphocyte cell line DT40 and its derivatives lacking nonhomologous end joining and/or homologous recombination pathways of DNA double-strand break repair. Radiat Res 2004 0.81
59 Potentiality of DNA-dependent protein kinase to phosphorylate Ser46 of human p53. Biochem Biophys Res Commun 2004 0.81
60 Significance of cancer-associated fibroblasts in the regulation of gene expression in the leading cells of invasive lung cancer. J Cancer Res Clin Oncol 2012 0.81
61 A novel Drosophila Girdin-like protein is involved in Akt pathway control of cell size. Exp Cell Res 2009 0.81
62 Role of human organic anion transporter 4 in the transport of ochratoxin A. Biochim Biophys Acta 2002 0.81
63 Expression of RET finger protein predicts chemoresistance in epithelial ovarian cancer. Cancer Med 2012 0.80
64 Loss of Sprouty2 partially rescues renal hypoplasia and stomach hypoganglionosis but not intestinal aganglionosis in Ret Y1062F mutant mice. Dev Biol 2010 0.80
65 Inhibition of DNA-dependent protein kinase promotes ultrasound-induced cell death including apoptosis in human leukemia cells. Cancer Lett 2012 0.80
66 Degeneration of retinal on bipolar cells induced by serum including autoantibody against TRPM1 in mouse model of paraneoplastic retinopathy. PLoS One 2013 0.80
67 GDNF-inducible zinc finger protein 1 is a sequence-specific transcriptional repressor that binds to the HOXA10 gene regulatory region. Nucleic Acids Res 2005 0.79
68 Effects of oral adsorbent on gene expression profile in uremic rat kidney: cDNA array analysis. Am J Kidney Dis 2003 0.79
69 Analysis of DOK-6 function in downstream signaling of RET in human neuroblastoma cells. Cancer Sci 2010 0.78
70 Human organic cation transporter 3 mediates the transport of antiarrhythmic drugs. Eur J Pharmacol 2004 0.78
71 Cycloheximide suppresses radiation-induced apoptosis in MOLT-4 cells with Arg72 variant of p53 through translational inhibition of p53 accumulation. J Radiat Res 2011 0.78
72 The transcription factor FoxB mediates temporal loss of cellular competence for notochord induction in ascidian embryos. Development 2011 0.78
73 Evaluation of zinc (II) chelators for inhibiting p53-mediated apoptosis. Oncotarget 2013 0.78
74 Nucleolin modulates the subcellular localization of GDNF-inducible zinc finger protein 1 and its roles in transcription and cell proliferation. Exp Cell Res 2007 0.77
75 Evaluation of osteopontin as a potential biomarker for central nervous system embryonal tumors. J Neurooncol 2014 0.77
76 Metamorphosis of mesothelial cells with active horizontal motility in tissue culture. Sci Rep 2013 0.77
77 Suppression of REV7 enhances cisplatin sensitivity in ovarian clear cell carcinoma cells. Cancer Sci 2014 0.77
78 Identification of the novel autoantigen candidate Rab GDP dissociation inhibitor alpha in isolated adrenocorticotropin deficiency. Endocr J 2014 0.77
79 Suramin sensitizing cells to ionizing radiation by inactivating DNA-dependent protein kinase. Radiat Res 2004 0.77
80 Proteomic analysis of Girdin-interacting proteins in migrating new neurons in the postnatal mouse brain. Biochem Biophys Res Commun 2013 0.77
81 Autoantibodies to transient receptor potential cation channel, subfamily M, member 1 in a Japanese patient with melanoma-associated retinopathy. Jpn J Ophthalmol 2014 0.76
82 An inhibitor of advanced glycation end product formation reduces N epsilon-(carboxymethyl)lysine accumulation in glomeruli of diabetic rats. Am J Kidney Dis 2003 0.76
83 Molecular mechanism linking BDNF/TrkB signaling with the NMDA receptor in memory: the role of Girdin in the CNS. Rev Neurosci 2016 0.75
84 Activation of c-Jun amino-terminal kinase by GDNF induces G2/M cell cycle delay linked with actin reorganization. Genes Cells 2005 0.75
85 [Urate transport in human kidney]. Nihon Rinsho 2003 0.75
86 [Molecular mechanisms for collective cell migration--perspectives and approaches from the studies on the actin-binding protein Girdin]. Nihon Rinsho 2016 0.75
87 [Mechanisms for the differentiation of postnatal and adult neural stem cells: new insights and pathological issues based on the analysis of Girdin]. Nihon Yakurigaku Zasshi 2014 0.75
88 Wortmannin-enhanced X-ray-induced apoptosis of human T-cell leukemia MOLT-4 cells possibly through the JNK/SAPK pathway. Radiat Res 2003 0.75
89 Analysis of glial cell line-derived neurotrophic factor-inducible zinc finger protein 1 expression in human diseased kidney. Hum Pathol 2011 0.75