Regina Goetz

Author PubWeight™ 53.32‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Endocrine regulation of the fasting response by PPARalpha-mediated induction of fibroblast growth factor 21. Cell Metab 2007 9.62
2 The parathyroid is a target organ for FGF23 in rats. J Clin Invest 2007 4.47
3 Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21. J Biol Chem 2007 4.42
4 BetaKlotho is required for metabolic activity of fibroblast growth factor 21. Proc Natl Acad Sci U S A 2007 4.00
5 FGF21 induces PGC-1alpha and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response. Proc Natl Acad Sci U S A 2009 3.99
6 A homozygous missense mutation in human KLOTHO causes severe tumoral calcinosis. J Clin Invest 2007 2.79
7 Inhibition of growth hormone signaling by the fasting-induced hormone FGF21. Cell Metab 2008 2.76
8 Research resource: Comprehensive expression atlas of the fibroblast growth factor system in adult mouse. Mol Endocrinol 2010 2.67
9 Analysis of the biochemical mechanisms for the endocrine actions of fibroblast growth factor-23. Endocrinology 2005 2.46
10 Fibroblast growth factor 21 promotes bone loss by potentiating the effects of peroxisome proliferator-activated receptor γ. Proc Natl Acad Sci U S A 2012 2.38
11 In vivo genetic evidence for klotho-dependent, fibroblast growth factor 23 (Fgf23) -mediated regulation of systemic phosphate homeostasis. FASEB J 2008 2.03
12 FGF23 decreases renal NaPi-2a and NaPi-2c expression and induces hypophosphatemia in vivo predominantly via FGF receptor 1. Am J Physiol Renal Physiol 2009 1.70
13 A protein canyon in the FGF-FGF receptor dimer selects from an à la carte menu of heparan sulfate motifs. Curr Opin Struct Biol 2005 1.69
14 FGF-23-Klotho signaling stimulates proliferation and prevents vitamin D-induced apoptosis. J Cell Biol 2008 1.53
15 Pregnane X receptor activation induces FGF19-dependent tumor aggressiveness in humans and mice. J Clin Invest 2011 1.27
16 Arterial klotho expression and FGF23 effects on vascular calcification and function. PLoS One 2013 1.09
17 Regulation of serum 1,25(OH)2 vitamin D3 levels by fibroblast growth factor 23 is mediated by FGF receptors 3 and 4. Am J Physiol Renal Physiol 2011 1.08
18 FGF23 acts directly on renal proximal tubules to induce phosphaturia through activation of the ERK1/2-SGK1 signaling pathway. Bone 2012 0.99
19 FGF23 promotes renal calcium reabsorption through the TRPV5 channel. EMBO J 2014 0.97
20 The alternatively spliced acid box region plays a key role in FGF receptor autoinhibition. Structure 2012 0.85
21 FGF23-induced hypophosphatemia persists in Hyp mice deficient in the WNT coreceptor Lrp6. Contrib Nephrol 2013 0.83
22 Corrigendum: Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer. Nature 2015 0.75