Published in Immunol Cell Biol on May 01, 2012
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Targeting polyIC to EGFR over-expressing cells using a dsRNA binding protein domain tethered to EGF. PLoS One (2016) 0.75
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Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation. Nat Immunol (2006) 3.94
STAT3 and STAT1 mediate IL-11-dependent and inflammation-associated gastric tumorigenesis in gp130 receptor mutant mice. J Clin Invest (2008) 2.95
Silencing of Irf7 pathways in breast cancer cells promotes bone metastasis through immune escape. Nat Med (2012) 2.66
Blocking monoclonal antibodies specific for mouse IFN-alpha/beta receptor subunit 1 (IFNAR-1) from mice immunized by in vivo hydrodynamic transfection. J Interferon Cytokine Res (2006) 2.56
Analysis of microRNA turnover in mammalian cells following Dicer1 ablation. Nucleic Acids Res (2011) 2.39
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Type I interferon receptors: biochemistry and biological functions. J Biol Chem (2007) 2.14
Interferome v2.0: an updated database of annotated interferon-regulated genes. Nucleic Acids Res (2012) 2.08
Suppressor of cytokine signaling 1 regulates the immune response to infection by a unique inhibition of type I interferon activity. Nat Immunol (2005) 2.01
GM-CSF- and M-CSF-dependent macrophage phenotypes display differential dependence on type I interferon signaling. J Leukoc Biol (2009) 2.00
Bacterial membrane vesicles deliver peptidoglycan to NOD1 in epithelial cells. Cell Microbiol (2009) 1.87
Interferon-ε protects the female reproductive tract from viral and bacterial infection. Science (2013) 1.73
Ets1 is required for p53 transcriptional activity in UV-induced apoptosis in embryonic stem cells. EMBO J (2002) 1.73
Type I-IFNs control GVHD and GVL responses after transplantation. Blood (2011) 1.54
Elf5 is essential for early embryogenesis and mammary gland development during pregnancy and lactation. EMBO J (2005) 1.52
The ETS transcription factor GABPalpha is essential for early embryogenesis. Mol Cell Biol (2004) 1.46
Structural basis of a unique interferon-β signaling axis mediated via the receptor IFNAR1. Nat Immunol (2013) 1.41
Functional crosstalk between type I and II interferon through the regulated expression of STAT1. PLoS Biol (2010) 1.40
IL-6 trans-signaling modulates TLR4-dependent inflammatory responses via STAT3. J Immunol (2010) 1.39
The role of type I interferons in TLR responses. Immunol Cell Biol (2007) 1.38
Characterization of the type I interferon locus and identification of novel genes. Genomics (2004) 1.36
MyD88 adapter-like (Mal)/TIRAP interaction with TRAF6 is critical for TLR2- and TLR4-mediated NF-kappaB proinflammatory responses. J Biol Chem (2009) 1.34
Mal interacts with tumor necrosis factor receptor-associated factor (TRAF)-6 to mediate NF-kappaB activation by toll-like receptor (TLR)-2 and TLR4. J Biol Chem (2004) 1.33
Suppressor of cytokine signaling (SOCS) 1 inhibits type I interferon (IFN) signaling via the interferon alpha receptor (IFNAR1)-associated tyrosine kinase Tyk2. J Biol Chem (2011) 1.17
Macrophage activation and differentiation signals regulate schlafen-4 gene expression: evidence for Schlafen-4 as a modulator of myelopoiesis. PLoS One (2011) 1.08
Type I interferon receptor controls B-cell expression of nucleic acid-sensing Toll-like receptors and autoantibody production in a murine model of lupus. Arthritis Res Ther (2009) 1.07
Macrophage lineage phenotypes and osteoclastogenesis--complexity in the control by GM-CSF and TGF-beta. Bone (2006) 1.00
Cutting edge: pulmonary Legionella pneumophila is controlled by plasmacytoid dendritic cells but not type I IFN. J Immunol (2010) 1.00
Potential contribution of NF-kappaB in neuronal cell death in the glutathione peroxidase-1 knockout mouse in response to ischemia-reperfusion injury. Stroke (2006) 0.99
An imbalance in antioxidant defense affects cellular function: the pathophysiological consequences of a reduction in antioxidant defense in the glutathione peroxidase-1 (Gpx1) knockout mouse. Redox Rep (2003) 0.98
A major site of expression of the ets transcription factor Elf5 is epithelia of exocrine glands. Histochem Cell Biol (2004) 0.97
A conserved IFN-alpha receptor tyrosine motif directs the biological response to type I IFNs. J Immunol (2008) 0.96
Type I IFN signaling in CD8- DCs impairs Th1-dependent malaria immunity. J Clin Invest (2014) 0.96
Ets2 is expressed during morphogenesis of the somite and limb in the mouse embryo. Mech Dev (2002) 0.95
The role of Ets2 transcription factor in the induction of microRNA-155 (miR-155) by lipopolysaccharide and its targeting by interleukin-10. J Biol Chem (2013) 0.93
TGF-betaRII rescues development of small intestinal epithelial cells in Elf3-deficient mice. Gastroenterology (2007) 0.92
Neonatal calyceal dilation and renal fibrosis resulting from loss of Adamts-1 in mouse kidney is due to a developmental dysgenesis. Nephrol Dial Transplant (2004) 0.90
The genomic profile of the cerebral cortex after closed head injury in mice: effects of minocycline. J Neural Transm (Vienna) (2008) 0.87
Absence of glutathione peroxidase-1 exacerbates cerebral ischemia-reperfusion injury by reducing post-ischemic microvascular perfusion. J Neurochem (2008) 0.86
Characterization and transcriptional analysis of the mouse Chromosome 16 cytokine receptor gene cluster. Mamm Genome (2003) 0.86
Targeting of the ETS factor GABPalpha disrupts neuromuscular junction synaptic function. Mol Cell Biol (2007) 0.86
Tissue-specific overexpression of the HSA21 gene GABPalpha: implications for DS. Biochim Biophys Acta (2004) 0.84
LPS hypersensitivity of gp130 mutant mice is independent of elevated haemopoietic TLR4 signaling. Immunol Cell Biol (2011) 0.84
Akt phosphorylation and NFkappaB activation are counterregulated under conditions of oxidative stress. Exp Cell Res (2004) 0.82
A human CD2 minigene directs CRE-mediated recombination in T cells in vivo. Genesis (2002) 0.81
RNA-eXpress annotates novel transcript features in RNA-seq data. Bioinformatics (2013) 0.81
Interferons as biomarkers and effectors: lessons learned from animal models. Biomark Med (2012) 0.81
Mitochondrially localised MUL1 is a novel modulator of antiviral signaling. Immunol Cell Biol (2013) 0.80
Multiple regions within the promoter of the murine Ifnar-2 gene confer basal and inducible expression. Biochem J (2002) 0.80
The early monocytic response to cytomegalovirus infection is MyD88 dependent but occurs independently of common inflammatory cytokine signals. Eur J Immunol (2013) 0.79
The Ets transcription factor ELF5 functions as a tumor suppressor in the kidney. Twin Res Hum Genet (2011) 0.79
Non-essential role for TLR2 and its signaling adaptor Mal/TIRAP in preserving normal lung architecture in mice. PLoS One (2013) 0.78
Identification and expression analysis of alternative transcripts of the mouse GA-binding protein (Gabp) subunits alpha and beta1. Gene (2004) 0.78
Constitutive activation of gp130 leads to neuroendocrine differentiation in vitro and in vivo. Prostate (2005) 0.78
The role of Type I interferons in immunoregulation of breast cancer metastasis to the bone. Oncoimmunology (2013) 0.77
CpG pretreatment enhances antiviral T-cell immunity against cytomegalovirus. Blood (2013) 0.77
Spatiotemporal requirements for IRF7 in mediating type I IFN-dependent susceptibility to blood-stage Plasmodium infection. Eur J Immunol (2014) 0.77
Transcript profiling of Elf5+/- mammary glands during pregnancy identifies novel targets of Elf5. PLoS One (2010) 0.76
Soluble IFN receptor potentiates in vivo type I IFN signaling and exacerbates TLR4-mediated septic shock. J Immunol (2014) 0.76
Endogenous interferon-alpha production by differentiating human monocytes regulates expression and function of the IL-2/IL-4 receptor gamma chain. Cytokine (2002) 0.76
Ultraviolet-induced apoptosis in embryonic stem cells in vitro. Methods Mol Biol (2006) 0.76
Chemokine receptor CCR5 is not required for development of experimental autoimmune gastritis. Clin Immunol (2003) 0.75
Comparison of mice born after intracytoplasmic sperm injection with in vitro fertilization and natural mating. Mol Reprod Dev (2007) 0.75