Published in Methods Mol Biol on January 01, 2012
Adenovirus serotype 5 hexon mediates liver gene transfer. Cell (2008) 5.00
IL-33 reduces the development of atherosclerosis. J Exp Med (2008) 3.59
Multiple vitamin K-dependent coagulation zymogens promote adenovirus-mediated gene delivery to hepatocytes. Blood (2006) 2.67
Identification of coagulation factor (F)X binding sites on the adenovirus serotype 5 hexon: effect of mutagenesis on FX interactions and gene transfer. Blood (2009) 2.55
Dynamic changes in lung microRNA profiles during the development of pulmonary hypertension due to chronic hypoxia and monocrotaline. Arterioscler Thromb Vasc Biol (2010) 2.44
Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension. PLoS Genet (2010) 2.24
Deregulation of microRNA-503 contributes to diabetes mellitus-induced impairment of endothelial function and reparative angiogenesis after limb ischemia. Circulation (2011) 1.99
Derivation of endothelial cells from human embryonic stem cells by directed differentiation: analysis of microRNA and angiogenesis in vitro and in vivo. Arterioscler Thromb Vasc Biol (2010) 1.63
A role for miR-145 in pulmonary arterial hypertension: evidence from mouse models and patient samples. Circ Res (2012) 1.61
The influence of adenovirus fiber structure and function on vector development for gene therapy. Mol Ther (2005) 1.54
Targeted gene delivery to vascular tissue in vivo by tropism-modified adeno-associated virus vectors. Circulation (2004) 1.50
Effect of adenovirus serotype 5 fiber and penton modifications on in vivo tropism in rats. Mol Ther (2004) 1.50
Vascular bed-targeted in vivo gene delivery using tropism-modified adeno-associated viruses. Mol Ther (2006) 1.49
Identification of novel small molecule inhibitors of adenovirus gene transfer using a high throughput screening approach. J Control Release (2013) 1.48
Tissue inhibitor of metalloproteinases-2 improves antitumor efficacy of a replicating adenovirus in vivo. Cancer Biol Ther (2006) 1.42
Heterogeneous effects of tissue inhibitors of matrix metalloproteinases on cardiac fibroblasts. Am J Physiol Heart Circ Physiol (2005) 1.40
Tissue inhibitor of metalloproteinases-3 induces apoptosis in melanoma cells by stabilization of death receptors. Oncogene (2003) 1.40
Suppression of atherosclerotic plaque progression and instability by tissue inhibitor of metalloproteinase-2: involvement of macrophage migration and apoptosis. Circulation (2006) 1.36
Heparan sulfate proteoglycan binding properties of adeno-associated virus retargeting mutants and consequences for their in vivo tropism. J Virol (2006) 1.35
Targeting of adenovirus serotype 5 (Ad5) and 5/47 pseudotyped vectors in vivo: fundamental involvement of coagulation factors and redundancy of CAR binding by Ad5. J Virol (2007) 1.29
Biodistribution and retargeting of FX-binding ablated adenovirus serotype 5 vectors. Blood (2010) 1.25
Tissue inhibitor of metalloproteinase-3 induces a Fas-associated death domain-dependent type II apoptotic pathway. J Biol Chem (2002) 1.22
Membrane-type 1-matrix metalloproteinase regulates intracellular adhesion molecule-1 (ICAM-1)-mediated monocyte transmigration. J Biol Chem (2007) 1.22
Development of efficient viral vectors selective for vascular smooth muscle cells. Mol Ther (2004) 1.20
Requirements for receptor engagement during infection by adenovirus complexed with blood coagulation factor X. PLoS Pathog (2010) 1.19
Role of microRNAs 99b, 181a, and 181b in the differentiation of human embryonic stem cells to vascular endothelial cells. Stem Cells (2012) 1.18
Tropism-modification strategies for targeted gene delivery using adenoviral vectors. Viruses (2010) 1.17
MicroRNA and vascular remodelling in acute vascular injury and pulmonary vascular remodelling. Cardiovasc Res (2011) 1.15
Adenovirus 5 fibers mutated at the putative HSPG-binding site show restricted retargeting with targeting peptides in the HI loop. Mol Ther (2007) 1.15
Lentivirus-mediated reprogramming of somatic cells in the absence of transgenic transcription factors. Mol Ther (2010) 1.13
Oxidation-sensitive mechanisms, vascular apoptosis and atherosclerosis. Trends Mol Med (2003) 1.10
miR-21 and miR-214 are consistently modulated during renal injury in rodent models. Am J Pathol (2011) 1.10
Influence of coagulation factor zymogens on the infectivity of adenoviruses pseudotyped with fibers from subgroup D. J Virol (2007) 1.09
Tissue inhibitor of metalloproteinase 1 inhibits excitotoxic cell death in neurons. Mol Cell Neurosci (2003) 1.05
Pluripotent stem cell differentiation into vascular cells: a novel technology with promises for vascular re(generation). Pharmacol Ther (2010) 1.05
In vivo modulation of Nogo-B attenuates neointima formation. Mol Ther (2008) 1.02
Images in cardiovascular medicine. Multiphoton microscopy for 3-dimensional imaging of lymphocyte recruitment into apolipoprotein-E-deficient mouse carotid artery. Circulation (2007) 1.02
Effect of neutralizing sera on factor x-mediated adenovirus serotype 5 gene transfer. J Virol (2008) 1.02
MicroRNAs in pulmonary arterial remodeling. Cell Mol Life Sci (2013) 0.99
Inhibition of urokinase-type plasminogen activator or matrix metalloproteinases prevents cardiac injury and dysfunction during viral myocarditis. Circulation (2006) 0.99
MicroRNA-214 antagonism protects against renal fibrosis. J Am Soc Nephrol (2013) 0.99
Sustained reduction of vein graft neointima formation by ex vivo TIMP-3 gene therapy. Circulation (2011) 0.98
Onset of experimental severe cardiac fibrosis is mediated by overexpression of Angiotensin-converting enzyme 2. Hypertension (2009) 0.97
Serotonin transporter, sex, and hypoxia: microarray analysis in the pulmonary arteries of mice identifies genes with relevance to human PAH. Physiol Genomics (2011) 0.97
Tropism-modified adenoviral and adeno-associated viral vectors for gene therapy. Curr Gene Ther (2002) 0.96
A cluster of basic amino acids in the factor X serine protease mediates surface attachment of adenovirus/FX complexes. J Virol (2011) 0.96
AAV-based gene transfer. Curr Opin Mol Ther (2003) 0.96
miRNA-21 is dysregulated in response to vein grafting in multiple models and genetic ablation in mice attenuates neointima formation. Eur Heart J (2013) 0.95
Angiotensin-(1-9) attenuates cardiac fibrosis in the stroke-prone spontaneously hypertensive rat via the angiotensin type 2 receptor. Hypertension (2011) 0.95
Influence of coagulation factor x on in vitro and in vivo gene delivery by adenovirus (Ad) 5, Ad35, and chimeric Ad5/Ad35 vectors. Mol Ther (2009) 0.95
Interactions of adenovirus vectors with blood: implications for intravascular gene therapy applications. Curr Opin Mol Ther (2008) 0.95
Arteriolar genesis and angiogenesis induced by endothelial nitric oxide synthase overexpression results in a mature vasculature. Arterioscler Thromb Vasc Biol (2008) 0.94
In vitro susceptibility to the pro-apoptotic effects of TIMP-3 gene delivery translates to greater in vivo efficacy versus gene delivery for TIMPs-1 or -2. Lung Cancer (2006) 0.94
Luciferin detection after intranasal vector delivery is improved by intranasal rather than intraperitoneal luciferin administration. Hum Gene Ther (2008) 0.94
Cell-selective viral gene delivery vectors for the vasculature. Exp Physiol (2004) 0.93
Ad5:Ad48 hexon hypervariable region substitutions lead to toxicity and increased inflammatory responses following intravenous delivery. Mol Ther (2012) 0.92
Stroma formation and angiogenesis by overexpression of growth factors, cytokines, and proteolytic enzymes in human skin grafted to SCID mice. J Invest Dermatol (2003) 0.92
Canonical transforming growth factor-β signaling regulates disintegrin metalloprotease expression in experimental renal fibrosis via miR-29. Am J Pathol (2013) 0.92
Overexpression of p53 increases lumen size and blocks neointima formation in porcine interposition vein grafts. Mol Ther (2004) 0.91
Collagenase-3 (MMP-13) enhances remodeling of three-dimensional collagen and promotes survival of human skin fibroblasts. J Invest Dermatol (2006) 0.90
An analysis of the function and expression of D6 on lymphatic endothelial cells. Blood (2013) 0.90
Adenovirus mediated gene delivery of tissue inhibitor of metalloproteinases-3 induces death in retinal pigment epithelial cells. Br J Ophthalmol (2002) 0.89
Antagonists of GPR35 display high species ortholog selectivity and varying modes of action. J Pharmacol Exp Ther (2012) 0.88
DRG-targeted helper-dependent adenoviruses mediate selective gene delivery for therapeutic rescue of sensory neuronopathies in mice. J Clin Invest (2009) 0.88
Antitumor activity and bystander effect of adenovirally delivered tissue inhibitor of metalloproteinases-3. Mol Ther (2002) 0.88
Biodistribution and inflammatory profiles of novel penton and hexon double-mutant serotype 5 adenoviruses. J Control Release (2012) 0.88
Third-generation lentivirus vectors efficiently transduce and phenotypically modify vascular cells: implications for gene therapy. J Mol Cell Cardiol (2003) 0.88
Adenoviral serotype 5 vectors pseudotyped with fibers from subgroup D show modified tropism in vitro and in vivo. Hum Gene Ther (2004) 0.88
Profiling of transcriptional and epigenetic changes during directed endothelial differentiation of human embryonic stem cells identifies FOXA2 as a marker of early mesoderm commitment. Stem Cell Res Ther (2013) 0.87
TIMP-3 promotes apoptosis in nonadherent small cell lung carcinoma cells lacking functional death receptor pathway. Int J Cancer (2011) 0.86
Inhibition of in-stent stenosis by oral administration of bindarit in porcine coronary arteries. Arterioscler Thromb Vasc Biol (2011) 0.86
Sorsby's fundus dystrophy mutant tissue inhibitors of metalloproteinase-3 induce apoptosis of retinal pigment epithelial and MCF-7 cells. FEBS Lett (2002) 0.86
In vitro and in vivo characterisation of endothelial cell selective adenoviral vectors. J Gene Med (2004) 0.86
Adenoviral delivery of angiotensin-(1-7) or angiotensin-(1-9) inhibits cardiomyocyte hypertrophy via the mas or angiotensin type 2 receptor. PLoS One (2012) 0.85
Targeting endothelial cells with adenovirus expressing nitric oxide synthase prevents elevation of blood pressure in stroke-prone spontaneously hypertensive rats. Mol Ther (2005) 0.85
Combined therapeutic benefit of mitochondria-targeted antioxidant, MitoQ10, and angiotensin receptor blocker, losartan, on cardiovascular function. J Hypertens (2014) 0.85