Published in BMC Med on June 07, 2012
The effect of omeprazole on the development of experimental autoimmune encephalomyelitis in C57BL/6J and SJL/J mice. BMC Res Notes (2014) 0.85
MRI findings of elevated intracranial pressure in cerebral venous thrombosis versus idiopathic intracranial hypertension with transverse sinus stenosis. Neuroophthalmology (2013) 0.81
Histamine H₂ receptor signaling × environment interactions determine susceptibility to experimental allergic encephalomyelitis. FASEB J (2013) 0.76
Acid suppression therapy and allergic reactions. Allergo J Int (2015) 0.75
Dendritic cells and the control of immunity. Nature (1998) 56.54
Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain. Nature (2003) 22.89
A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosis. N Engl J Med (2006) 11.29
Interleukin-17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis. Am J Pathol (2007) 5.27
Recognition of peptidoglycan from the microbiota by Nod1 enhances systemic innate immunity. Nat Med (2010) 4.98
Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosis. Mult Scler (1999) 4.91
Mechanisms of fingolimod's efficacy and adverse effects in multiple sclerosis. Ann Neurol (2011) 2.85
T-helper 17 cells expand in multiple sclerosis and are inhibited by interferon-beta. Ann Neurol (2009) 2.65
Inflammatory mediators and modulation of blood-brain barrier permeability. Cell Mol Neurobiol (2000) 2.64
Brain dendritic cells and macrophages/microglia in central nervous system inflammation. J Immunol (2001) 2.38
Inhibition of histamine release by histamine controlled by H2 receptor. Nature (1973) 2.19
The Th17-ELR+ CXC chemokine pathway is essential for the development of central nervous system autoimmune disease. J Exp Med (2008) 2.15
Omeprazole treatment diminishes intra- and extracellular neutrophil reactive oxygen production and bactericidal activity. Crit Care Med (2002) 2.14
Decreased interleukin-10 and increased interleukin-12p40 mRNA are associated with disease activity and characterize different disease stages in multiple sclerosis. Ann Neurol (1999) 1.99
Role of gut commensal microflora in the development of experimental autoimmune encephalomyelitis. J Immunol (2009) 1.99
Review article: proton pump inhibitors and bacterial overgrowth. Aliment Pharmacol Ther (2006) 1.94
Potential anti-inflammatory effects of proton pump inhibitors: a review and discussion of the clinical implications. Dig Dis Sci (2009) 1.91
Diversity in the contribution of interleukin-10 to T-cell-mediated immune regulation. Immunol Rev (2008) 1.88
Two subsets of dendritic cells are present in human cerebrospinal fluid. Brain (2001) 1.78
IL-23 is increased in dendritic cells in multiple sclerosis and down-regulation of IL-23 by antisense oligos increases dendritic cell IL-10 production. J Immunol (2006) 1.72
Histamine potently suppresses human IL-12 and stimulates IL-10 production via H2 receptors. J Immunol (1998) 1.59
T helper cell type 1 (Th1), Th2 and Th17 responses to myelin basic protein and disease activity in multiple sclerosis. Immunology (2008) 1.59
Anti-ulcer drugs promote IgE formation toward dietary antigens in adult patients. FASEB J (2005) 1.50
A new mechanism for anti-inflammatory actions of proton pump inhibitors--inhibitory effects on neutrophil-endothelial cell interactions. Aliment Pharmacol Ther (2000) 1.48
TGF-β: the sword, the wand, and the shield of FOXP3(+) regulatory T cells. J Mol Cell Biol (2011) 1.47
A 3-year magnetic resonance imaging study of cortical lesions in relapse-onset multiple sclerosis. Ann Neurol (2010) 1.46
The immunoregulatory abilities of polymorphonuclear neutrophils in the course of multiple sclerosis. Mediators Inflamm (1998) 1.45
Histamine regulates cytokine production in maturing dendritic cells, resulting in altered T cell polarization. J Clin Invest (2001) 1.43
Role of the innate immune system in the pathogenesis of multiple sclerosis. J Neuroimmunol (2010) 1.42
Initiation and progression of axonopathy in experimental autoimmune encephalomyelitis. J Neurosci (2009) 1.41
Gastric acid is the key modulator in the pathogenesis of non-steroidal anti-inflammatory drug-induced ulceration in rats. Clin Exp Pharmacol Physiol (2010) 1.39
Antacid medication inhibits digestion of dietary proteins and causes food allergy: a fish allergy model in BALB/c mice. J Allergy Clin Immunol (2003) 1.38
Molecular mechanisms involved in anti-inflammatory effects of proton pump inhibitors. Inflamm Res (2006) 1.37
C5a receptor-deficient dendritic cells promote induction of Treg and Th17 cells. Eur J Immunol (2010) 1.34
Cimetidine-associated exacerbation of cutaneous lupus erythematosus. Arch Intern Med (1982) 1.34
Meningeal mast cells affect early T cell central nervous system infiltration and blood-brain barrier integrity through TNF: a role for neutrophil recruitment? J Immunol (2010) 1.31
Activated microglia mediate axoglial disruption that contributes to axonal injury in multiple sclerosis. J Neuropathol Exp Neurol (2010) 1.27
Inhibition of T suppressor cell expression by histamine type 2 (H2) receptor antagonists. J Immunol (1984) 1.25
The role of iron in the pathogenesis of experimental allergic encephalomyelitis and multiple sclerosis. Ann N Y Acad Sci (2004) 1.25
Pharmacology of proton pump inhibitors. Curr Gastroenterol Rep (2008) 1.25
A case-control study on adverse effects: H2 blocker or proton pump inhibitor use and risk of vitamin B12 deficiency in older adults. J Clin Epidemiol (2004) 1.23
Multiple elements of the allergic arm of the immune response modulate autoimmune demyelination. Proc Natl Acad Sci U S A (2003) 1.23
Histamine polarizes human dendritic cells into Th2 cell-promoting effector dendritic cells. J Immunol (2001) 1.22
Tumor necrosis factor-alpha messenger RNA expression in patients with relapsing-remitting multiple sclerosis is associated with disease activity. Ann Neurol (1995) 1.20
Histamine inhibits the production of interleukin-12 through interaction with H2 receptors. J Clin Invest (1998) 1.20
Evidence of persistent blood-brain barrier abnormalities in chronic-progressive multiple sclerosis. Acta Neuropathol (1995) 1.20
EFNS guideline on treatment of multiple sclerosis relapses: report of an EFNS task force on treatment of multiple sclerosis relapses. Eur J Neurol (2005) 1.20
Vitamin B12, demyelination, remyelination and repair in multiple sclerosis. J Neurol Sci (2005) 1.18
Antiulcer drugs promote oral sensitization and hypersensitivity to hazelnut allergens in BALB/c mice and humans. Am J Clin Nutr (2005) 1.18
Patterns of cytokine secretion by autoreactive proteolipid protein-specific T cell clones during the course of multiple sclerosis. J Immunol (1995) 1.16
IL-10-dependent infectious tolerance after the treatment of experimental allergic encephalomyelitis with redirected CD4+CD25+ T lymphocytes. Proc Natl Acad Sci U S A (2005) 1.16
Cimetidine-induced augmentation of human lymphocyte blastogenesis by mitogen, bacterial antigen, and alloantigen. Transplantation (1980) 1.15
Omeprazole attenuates oxygen-derived free radical production from human neutrophils. Free Radic Biol Med (1996) 1.11
Interleukin-6 promotes post-traumatic healing in the central nervous system. Brain Res (2001) 1.11
Histamine and prostaglandin E up-regulate the production of Th2-attracting chemokines (CCL17 and CCL22) and down-regulate IFN-gamma-induced CXCL10 production by immature human dendritic cells. Immunology (2006) 1.10
Hypergastrinemia induced by glucocorticoid and corticotropin treatment in man. Am J Dig Dis (1976) 1.09
Histamine and histamine receptors in pathogenesis and treatment of multiple sclerosis. Neuropharmacology (2010) 1.07
Neutrophils in multiple sclerosis are characterized by a primed phenotype. J Neuroimmunol (2011) 1.07
Histamine suppresses gene expression and synthesis of tumor necrosis factor alpha via histamine H2 receptors. J Exp Med (1991) 1.06
Possible roles of microglial cells for neurotoxicity in clinical neurodegenerative diseases and experimental animal models. Inflamm Allergy Drug Targets (2009) 1.05
Relapsing-remitting multiple sclerosis: sequential enhanced MR imaging vs clinical findings in determining disease activity. AJR Am J Roentgenol (1992) 1.05
Neutrophils that infiltrate the central nervous system regulate T cell responses. J Immunol (2005) 1.05
Ranitidine, diarrhoea, and lymphocytic colitis. Gut (1995) 1.04
Corticosteroids inhibit the production of inflammatory mediators in immature monocyte-derived DC and induce the development of tolerogenic DC3. J Leukoc Biol (1999) 1.03
Histamine in allergic inflammation and immune modulation. Int Arch Allergy Immunol (2005) 1.03
Anti-ulcer treatment during pregnancy induces food allergy in mouse mothers and a Th2-bias in their offspring. FASEB J (2007) 1.03
Histamine and histamine-N-methyltransferase in the CSF of patients with multiple sclerosis. Agents Actions (1983) 1.03
Inhibition of suppressor T lymphocytes (Ts) by cimetidine. J Immunol (1987) 0.99
Conventional dose of omeprazole alters gastric flora. Dig Dis Sci (1995) 0.98
Multiple sclerosis is associated with high levels of circulating dendritic cells secreting pro-inflammatory cytokines. J Neuroimmunol (1999) 0.96
Lansoprazole decreases peripheral blood monocytes and intercellular adhesion molecule-1-positive mononuclear cells. Dig Dis Sci (1999) 0.96
A key regulatory role for histamine in experimental autoimmune encephalomyelitis: disease exacerbation in histidine decarboxylase-deficient mice. J Immunol (2006) 0.95
Histamine induces IL-6 production by human endothelial cells. Clin Exp Immunol (1994) 0.95
Histamine inhibits interleukin 1 production by lipopolysaccharide-stimulated human peripheral blood monocytes. Scand J Immunol (1988) 0.95
Ranitidine improves postoperative monocyte and neutrophil function. Arch Surg (1994) 0.94
Enhancement of neutrophil infiltration in histidine decarboxylase-deficient mice. Immunology (2002) 0.94
Meta-analysis of the relationship between homocysteine, vitamin B₁₂, folate, and multiple sclerosis. J Clin Neurosci (2011) 0.94
The impact of aluminium in acid-suppressing drugs on the immune response of BALB/c mice. Clin Exp Allergy (2007) 0.93
Methylprednisolone therapy in multiple sclerosis: a profile of adverse effects. J Neurol Neurosurg Psychiatry (1988) 0.93
Neutrophils secreting tumor necrosis factor alpha infiltrate the central nervous system of BALB/c mice with experimental autoimmune encephalomyelitis. J Neuroimmunol (1998) 0.93
Histamine inhibits tumor necrosis factor alpha release by mast cells through H2 and H3 receptors. Am J Respir Cell Mol Biol (1996) 0.91
Effects of acid suppression on microbial flora of upper gut. Dig Dis Sci (1995) 0.90
Activation of histamine H2 receptors ameliorates experimental allergic encephalomyelitis. Neuroreport (2002) 0.89
IL-6 deficiency causes enhanced pathology in Twitcher (globoid cell leukodystrophy) mice. Exp Neurol (1999) 0.89
Adherent dendritic cells expressing high levels of interleukin-10 and low levels of interleukin-12 induce antigen-specific tolerance to experimental autoimmune encephalomyelitis. Immunology (2000) 0.89
Cytokine shifts and tolerance in experimental autoimmune encephalomyelitis. Immunol Res (2003) 0.88
The T-cell pool is anergized in patients with multiple sclerosis in remission. Immunology (2008) 0.88
Corticosteroids for multiple sclerosis: I. Application for treating exacerbations. Neurotherapeutics (2007) 0.88
Histamine-induced inhibition of neutrophil chemotaxis and T-lymphocyte proliferation in man. Allergy (1992) 0.88
Exacerbated experimental autoimmune encephalomyelitis in mast-cell-deficient Kit W-sh/W-sh mice. Lab Invest (2011) 0.87
Histamine content of the cerebrospinal fluid in multiple sclerosis. A preliminary communication. Acta Med Acad Sci Hung (1966) 0.87
Aluminium per se and in the anti-acid drug sucralfate promotes sensitization via the oral route. Allergy (2009) 0.86
Histamine regulates autoreactive T cell activation and adhesiveness in inflamed brain microcirculation. J Leukoc Biol (2010) 0.85
Proton pump inhibitors exert anti-inflammatory effects and decrease human microglial and monocytic THP-1 cell neurotoxicity. Exp Neurol (2009) 0.84
Histamine modulates multiple functional activities of monocyte-derived dendritic cell subsets via histamine receptor 2. Int Immunol (2012) 0.84
Cimetidine enhances immune response of HBV DNA vaccination via impairment of the regulatory function of regulatory T cells. Biochem Biophys Res Commun (2008) 0.84
Histamine acts directly on human T cells to inhibit interleukin-2 and interferon-gamma production. Cell Immunol (1987) 0.83
Cutting edge: resistance to Bacillus anthracis infection mediated by a lethal toxin sensitive allele of Nalp1b/Nlrp1b. J Immunol (2009) 1.63
The prevalence of multiple sclerosis in 3 US communities. Prev Chronic Dis (2009) 1.36
Statistical analysis of data from studies on experimental autoimmune encephalomyelitis. J Neuroimmunol (2005) 1.35
Pathophysiological manifestations in mice exposed to anthrax lethal toxin. Infect Immun (2005) 1.19
Objective adherence monitoring in multiple sclerosis: initial validation and association with self-report. Mult Scler (2009) 1.16
Pathogenic implications of iron accumulation in multiple sclerosis. J Neurochem (2011) 1.16
The relationship between perceived and objective cognitive functioning in multiple sclerosis. Arch Clin Neuropsychol (2006) 1.15
Substrate-reduction therapy enhances the benefits of bone marrow transplantation in young mice with globoid cell leukodystrophy. Pediatr Res (2002) 1.08
Stimulation through intercellular adhesion molecule-1 provides a second signal for T cell activation. J Immunol (2002) 1.07
Post-acute pathological changes in the thalamus and internal capsule in aged mice following controlled cortical impact injury: a magnetic resonance imaging, iron histochemical, and glial immunohistochemical study. Neurosci Lett (2009) 0.97
Experimental allergic encephalomyelitis is exacerbated in mice deficient for 12/15-lipoxygenase or 5-lipoxygenase. Brain Res (2004) 0.97
Recombinant T-Cell Receptor Ligand (RTL) for Treatment of Multiple Sclerosis: A Double-Blind, Placebo-Controlled, Phase 1, Dose-Escalation Study. Autoimmune Dis (2012) 0.93
Immunohistochemical localization of phosphorylated protein kinase R and phosphorylated eukaryotic initiation factor-2 alpha in the central nervous system of SJL mice with experimental allergic encephalomyelitis. J Neurosci Res (2004) 0.93
Cognitive impairment in three subtypes of multiple sclerosis. Arch Clin Neuropsychol (2005) 0.91
Activation of histamine H2 receptors ameliorates experimental allergic encephalomyelitis. Neuroreport (2002) 0.89
Multiple sclerosis: MS treatment adherence--how to keep patients on medication? Nat Rev Neurol (2011) 0.88
The Salmonella type III secretion system inner rod protein PrgJ is partially folded. J Biol Chem (2012) 0.88
Enhancing the ability of experimental autoimmune encephalomyelitis to serve as a more rigorous model of multiple sclerosis through refinement of the experimental design. Comp Med (2009) 0.87
The impact of multiple sclerosis on patients' performance on the Stroop Test: processing speed versus interference. J Int Neuropsychol Soc (2009) 0.87
Cognitive impairment in relapsing and primary progressive multiple sclerosis: mostly a matter of speed. J Int Neuropsychol Soc (2004) 0.87
The cognitive performance of patients with multiple sclerosis during periods of high and low fatigue. Mult Scler (2003) 0.86
Costimulation of naive human CD4 T cells through intercellular adhesion molecule-1 promotes differentiation to a memory phenotype that is not strictly the result of multiple rounds of cell division. Immunology (2006) 0.86
Allelic variation on murine chromosome 11 modifies host inflammatory responses and resistance to Bacillus anthracis. PLoS Pathog (2011) 0.85
Personality traits in multiple sclerosis: association with mood and anxiety disorders. J Psychosom Res (2011) 0.85
Iron deposition is independent of cellular inflammation in a cerebral model of multiple sclerosis. BMC Neurosci (2011) 0.85
Substrate reduction intervention by L-cycloserine in twitcher mice (globoid cell leukodystrophy) on a B6;CAST/Ei background. Neurosci Lett (2003) 0.83
The outcome of T-cell costimulation through intercellular adhesion molecule-1 differs from costimulation through leucocyte function-associated antigen-1. Immunology (2003) 0.83
A 3-year longitudinal study of cognitive impairment in patients with primary progressive multiple sclerosis: speed matters. J Neurol Sci (2007) 0.82
Inflammatory mediators and immune function are altered in home parenteral nutrition patients. Nutrition (2006) 0.81
Processing speed and working memory training in multiple sclerosis: a double-blind randomized controlled pilot study. J Clin Exp Neuropsychol (2015) 0.81
Individual variability in speed of information processing: an index of cognitive impairment in multiple sclerosis. Neuropsychology (2012) 0.81
Quantifying immunohistochemical staining of phospho-eIF2alpha, heme oxygenase-2 and NADPH cytochrome P450 reductase in oligodendrocytes during experimental autoimmune encephalomyelitis. J Neurosci Methods (2005) 0.80
Deficits in processing speed in patients with multiple sclerosis: evidence from explicit and covert measures. Arch Clin Neuropsychol (2011) 0.79
Anthrax toxin delivers a one-two punch. Cell Host Microbe (2010) 0.79
MIP-1alpha induces differential MAP kinase activation and IkappaB gene expression in human B lymphocytes. J Interferon Cytokine Res (2004) 0.79
Variations in rodent models of type 1 diabetes: islet morphology. J Diabetes Res (2013) 0.79
Choice of resident costimulatory molecule can influence cell fate in human naïve CD4+ T cell differentiation. Cell Immunol (2011) 0.78
Omega-3 fatty acids and multiple sclerosis: relationship to depression. J Behav Med (2008) 0.78
Delayed clinical and pathological signs in twitcher (globoid cell leukodystrophy) mice on a C57BL/6 x CAST/Ei background. Neurobiol Dis (2002) 0.78
Reaction time and rapid serial processing measures of information processing speed in multiple sclerosis: complexity, compounding, and augmentation. J Int Neuropsychol Soc (2011) 0.77
Iron accumulation in multiple sclerosis: an early pathogenic event. Expert Rev Neurother (2013) 0.77
Rapid serial processing in patients with multiple sclerosis: the role of peripheral deficits. J Int Neuropsychol Soc (2008) 0.76
Information processing speed and attention in multiple sclerosis: Reconsidering the Attention Network Test (ANT). J Clin Exp Neuropsychol (2015) 0.76
Deferiprone modulates in vitro responses by peripheral blood T cells from control and relapsing-remitting multiple sclerosis subjects. Int Immunopharmacol (2011) 0.76
Deficits in planning time but not performance in patients with multiple sclerosis. Arch Clin Neuropsychol (2011) 0.76
Influence of carbohydrate ingestion on cytokine responses following acute resistance exercise. Int J Sport Nutr Exerc Metab (2003) 0.76
Exacerbation history is associated with medication and appointment adherence in MS. J Behav Med (2011) 0.76
Difficulties in planning among patients with multiple sclerosis: a relative consequence of deficits in information processing speed. J Int Neuropsychol Soc (2013) 0.76
Rapid vascular responses to anthrax lethal toxin in mice containing a segment of chromosome 11 from the CAST/Ei strain on a C57BL/6 genetic background. PLoS One (2012) 0.75
Elimination of T cell reactivity to pancreatic β cells and partial preservation of β cell activity by peptide blockade of LFA-1:ICAM-1 interaction in the NOD mouse model. Clin Immunol (2013) 0.75
Two different modes of costimulation predispose human T lymphocytes to differential responses in the presence of HDL or oxidized LDL. Atherosclerosis (2006) 0.75
Procedural Variations in the Stroop and the Symbol Digit Modalities Test: impact on patients with multiple sclerosis. Arch Clin Neuropsychol (2013) 0.75
Cognitive aging in patients with multiple sclerosis: a cross-sectional analysis of speeded processing. Arch Clin Neuropsychol (2009) 0.75