John E Pearson

Author PubWeight™ 17.62^‹?›

Top papers

Rank	Title	Journal	Year	PubWeight™‹?›
1	Using independent open-to-closed transitions to simplify aggregated Markov models of ion channel gating kinetics.	Proc Natl Acad Sci U S A	2005	1.87
2	Phi-value analysis of a linear, sequential reaction mechanism: theory and application to ion channel gating.	Biophys J	2005	1.80
3	A kinetic model of single and clustered IP3 receptors in the absence of Ca2+ feedback.	Biophys J	2007	1.48
4	On imposing detailed balance in complex reaction mechanisms.	Biophys J	2006	1.28
5	Rapid ligand-regulated gating kinetics of single inositol 1,4,5-trisphosphate receptor Ca2+ release channels.	EMBO Rep	2007	1.26
6	Mode switching is the major mechanism of ligand regulation of InsP3 receptor calcium release channels.	J Gen Physiol	2007	1.24
7	A data-driven model of a modal gated ion channel: the inositol 1,4,5-trisphosphate receptor in insect Sf9 cells.	J Gen Physiol	2012	1.07
8	Modeling Ca2+ feedback on a single inositol 1,4,5-trisphosphate receptor and its modulation by Ca2+ buffers.	Biophys J	2008	1.00
9	Multi-scale data-driven modeling and observation of calcium puffs.	Cell Calcium	2012	0.99
10	Messages diffuse faster than messengers.	Proc Natl Acad Sci U S A	2006	0.97
11	Sheet excitability and nonlinear wave propagation.	Phys Rev Lett	2003	0.83
12	Simplification of reversible Markov chains by removal of states with low equilibrium occupancy.	J Theor Biol	2012	0.83
13	Automated maximum likelihood separation of signal from baseline in noisy quantal data.	Biophys J	2013	0.82
14	Permeant calcium ion feed-through regulation of single inositol 1,4,5-trisphosphate receptor channel gating.	J Gen Physiol	2012	0.81
15	Transformations that preserve detailed balance in Markov models.	J Comput Biol	2006	0.78
16	Origins of concentration dependence of waiting times for single-molecule fluorescence binding.	J Chem Phys	2012	0.75