Published in Drug Metab Dispos on June 14, 2012
Epigenetic effects of RRx-001: a possible unifying mechanism of anticancer activity. Oncotarget (2015) 1.08
NO to cancer: The complex and multifaceted role of nitric oxide and the epigenetic nitric oxide donor, RRx-001. Redox Biol (2015) 0.90
Nrf2 activity as a potential biomarker for the pan-epigenetic anticancer agent, RRx-001. Oncotarget (2015) 0.82
A novel hypoxia-selective epigenetic agent RRx-001 triggers apoptosis and overcomes drug resistance in multiple myeloma cells. Leukemia (2016) 0.82
Impact of hemoglobin nitrite to nitric oxide reductase on blood transfusion for resuscitation from hemorrhagic shock. Asian J Transfus Sci (2015) 0.81
From METS to malaria: RRx-001, a multi-faceted anticancer agent with activity in cerebral malaria. Malar J (2015) 0.79
RRx-001, A novel dinitroazetidine radiosensitizer. Invest New Drugs (2016) 0.79
Real time dynamic imaging and current targeted therapies in the war on cancer: a new paradigm. Theranostics (2013) 0.78
Whole Brain Radiotherapy and RRx-001: Two Partial Responses in Radioresistant Melanoma Brain Metastases from a Phase I/II Clinical Trial: A TITE-CRM Phase I/II Clinical Trial. Transl Oncol (2016) 0.77
The implications of hyponitroxia in cancer. Transl Oncol (2014) 0.76
Metabolic disposition of the anti-cancer agent [(14)C]laromustine in male rats. Xenobiotica (2015) 0.75
An overview of second generation biofuel technologies. Bioresour Technol (2009) 2.95
Enhanced locomotion caused by loss of the Drosophila DEG/ENaC protein Pickpocket1. Curr Biol (2003) 2.25
mRNA expression signatures of human skeletal muscle atrophy identify a natural compound that increases muscle mass. Cell Metab (2011) 2.11
Demographically corrected norms for African Americans and Caucasians on the Hopkins Verbal Learning Test-Revised, Brief Visuospatial Memory Test-Revised, Stroop Color and Word Test, and Wisconsin Card Sorting Test 64-Card Version. J Clin Exp Neuropsychol (2011) 2.06
Persistence of HIV-associated cognitive impairment, inflammation, and neuronal injury in era of highly active antiretroviral treatment. AIDS (2011) 2.04
Recovery from chronic factitious disorder (Munchausen's syndrome): a personal account. Personal Ment Health (2013) 2.04
Effectiveness of first-line management strategies for stage I follicular lymphoma: analysis of the National LymphoCare Study. J Clin Oncol (2012) 1.99
Effects of nadir CD4 count and duration of human immunodeficiency virus infection on brain volumes in the highly active antiretroviral therapy era. J Neurovirol (2010) 1.95
Evolution of dithiane-based strategies for the construction of architecturally complex natural products. Acc Chem Res (2004) 1.91
Effects of central nervous system antiretroviral penetration on cognitive functioning in the ALLRT cohort. AIDS (2011) 1.90
p53 rescue through HDM2 antagonism suppresses melanoma growth and potentiates MEK inhibition. J Invest Dermatol (2011) 1.77
Germline BAP1 inactivation is preferentially associated with metastatic ocular melanoma and cutaneous-ocular melanoma families. PLoS One (2012) 1.76
Interventions to improve safe and effective medicines use by consumers: an overview of systematic reviews. Cochrane Database Syst Rev (2014) 1.58
Architecture of an RNA polymerase II transcription pre-initiation complex. Science (2013) 1.52
Disposition of posaconazole following single-dose oral administration in healthy subjects. Antimicrob Agents Chemother (2004) 1.46
Performance and microbial community analysis of the anaerobic reactor with coke oven gas biomethanation and in situ biogas upgrading. Bioresour Technol (2013) 1.45
Electron capture dissociation proceeds with a low degree of intramolecular migration of peptide amide hydrogens. J Am Chem Soc (2008) 1.40
Experimental determination of net protein charge, [A]tot, and Ka of nonvolatile buffers in bird plasma. J Appl Physiol (1985) (2006) 1.39
TOF-SIMS analysis of a 576 micropatterned copolymer array to reveal surface moieties that control wettability. Anal Chem (2007) 1.38
Subunit order of eukaryotic TRiC/CCT chaperonin by cross-linking, mass spectrometry, and combinatorial homology modeling. Proc Natl Acad Sci U S A (2012) 1.36
Atf4 regulates obesity, glucose homeostasis, and energy expenditure. Diabetes (2009) 1.34
Magnetic resonance derived myocardial strain assessment using feature tracking. J Vis Exp (2011) 1.32
Quantification of accuracy and precision of multi-center DTI measurements: a diffusion phantom and human brain study. Neuroimage (2011) 1.30
Three mutations in sterol-sensing domain of SCAP block interaction with insig and render SREBP cleavage insensitive to sterols. Proc Natl Acad Sci U S A (2002) 1.28
HIV suppression by HAART preserves cognitive function in advanced, immune-reconstituted AIDS patients. AIDS (2007) 1.25
Evaluation of a prototype Minified Augmented-View device for patients with impaired night vision. Ophthalmic Physiol Opt (2004) 1.25
Dinitroazetidines are a novel class of anticancer agents and hypoxia-activated radiation sensitizers developed from highly energetic materials. Cancer Res (2012) 1.24
The transcription factor ATF4 promotes skeletal myofiber atrophy during fasting. Mol Endocrinol (2010) 1.23
Cerebral metabolite abnormalities in human immunodeficiency virus are associated with cortical and subcortical volumes. J Neurovirol (2010) 1.22
Conformational instability of the cholera toxin A1 polypeptide. J Mol Biol (2007) 1.22
Functional adaptation skills training (FAST): a pilot psychosocial intervention study in middle-aged and older patients with chronic psychotic disorders. Am J Geriatr Psychiatry (2003) 1.20
Coverage bias and sensitivity of variant calling for four whole-genome sequencing technologies. PLoS One (2013) 1.20
Polymer surface functionalities that control human embryoid body cell adhesion revealed by high throughput surface characterization of combinatorial material microarrays. Biomaterials (2010) 1.18
Electron ionization dissociation of singly and multiply charged peptides. J Am Chem Soc (2009) 1.18
9-[(Furan-2-ylmeth-yl)amino]-5-(3,4,5-trimeth-oxy-phen-yl)-5,5a,8a,9-tetra-hydro-furo[3',4':6,7]naphtho-[2,3-d][1,3]dioxol-6(8H)-one. Acta Crystallogr Sect E Struct Rep Online (2011) 1.17
Skeletal muscle denervation causes skeletal muscle atrophy through a pathway that involves both Gadd45a and HDAC4. Am J Physiol Endocrinol Metab (2013) 1.17
Stress-induced skeletal muscle Gadd45a expression reprograms myonuclei and causes muscle atrophy. J Biol Chem (2012) 1.13
Using chimeric mice with humanized livers to predict human drug metabolism and a drug-drug interaction. J Pharmacol Exp Ther (2012) 1.11
Metabolic activation of nevirapine in human liver microsomes: dehydrogenation and inactivation of cytochrome P450 3A4. Drug Metab Dispos (2009) 1.10
Total synthesis of (+)-13-deoxytedanolide. J Am Chem Soc (2003) 1.07
Episensitization: therapeutic tumor resensitization by epigenetic agents: a review and reassessment. Anticancer Agents Med Chem (2014) 1.07
Early cardiac dysfunction in pediatric patients on maintenance dialysis and post kidney transplant. Pediatr Nephrol (2012) 1.05
Atypical teratoid or rhabdoid tumors: improved outcome with high-dose chemotherapy. J Pediatr Hematol Oncol (2010) 1.05
Mouse liver CYP2C39 is a novel retinoic acid 4-hydroxylase. Its down-regulation offers a molecular basis for liver retinoid accumulation and fibrosis in aryl hydrocarbon receptor-null mice. J Biol Chem (2003) 1.04
Ursolic acid increases skeletal muscle and brown fat and decreases diet-induced obesity, glucose intolerance and fatty liver disease. PLoS One (2012) 1.04
Effects of non-surgical periodontal treatment on clinical response, serum inflammatory parameters, and metabolic control in patients with type 2 diabetes: a randomized study. J Periodontol (2011) 1.04
KARDIA: a Matlab software for the analysis of cardiac interbeat intervals. Comput Methods Programs Biomed (2009) 1.01
Insulin signaling and the general amino acid control response. Two distinct pathways to amino acid synthesis and uptake. J Biol Chem (2008) 1.00
Applications of Augmented Vision Head-Mounted Systems in Vision Rehabilitation. J Soc Inf Disp (2007) 0.99
Stabilization of the tertiary structure of the cholera toxin A1 subunit inhibits toxin dislocation and cellular intoxication. J Mol Biol (2009) 0.99
Hypertrophic cardiomyopathy and dysregulation of cardiac energetics in a mouse model of biliary fibrosis. Hepatology (2010) 0.99
Bifurcating fragmentation behavior of gas-phase tryptic peptide dications in collisional activation. J Am Soc Mass Spectrom (2008) 0.98
In vitro and in vivo antitumor effects of acetylshikonin isolated from Arnebia euchroma (Royle) Johnst (Ruanzicao) cell suspension cultures. Chin Med (2009) 0.98
Microbead-induced ocular hypertensive mouse model for screening and testing of aqueous production suppressants for glaucoma. Invest Ophthalmol Vis Sci (2012) 0.96
2-(Quinazolin-4-ylamino)-[1,4]benzoquinones as covalent-binding, irreversible inhibitors of the kinase domain of vascular endothelial growth factor receptor-2. J Med Chem (2005) 0.96
Establishing Mobility Measures to Assess the Effectiveness of Night Vision Devices: Results of a Pilot Study. J Vis Impair Blind (2005) 0.95
Effects of contour enhancement on low-vision preference and visual search. Optom Vis Sci (2012) 0.95
DNA methyltransferase 1-associated protein (DMAP1) is a co-repressor that stimulates DNA methylation globally and locally at sites of double strand break repair. J Biol Chem (2010) 0.95
Vemurafenib synergizes with nutlin-3 to deplete survivin and suppresses melanoma viability and tumor growth. Clin Cancer Res (2013) 0.95
Progressive cerebral injury in the setting of chronic HIV infection and antiretroviral therapy. J Neurovirol (2013) 0.95
High throughput surface characterization: A review of a new tool for screening prospective biomedical material arrays. J Drug Target (2010) 0.94
Rapamycin (sirolimus) in tuberous sclerosis associated pediatric central nervous system tumors. Pediatr Blood Cancer (2010) 0.94
Contribution of subdomain structure to the thermal stability of the cholera toxin A1 subunit. Biochemistry (2010) 0.93
Telescope aiming point tracking method for bioptic driving surveillance. IEEE Trans Neural Syst Rehabil Eng (2010) 0.93
Downregulation of heparanase by RNA interference inhibits invasion and tumorigenesis of hepatocellular cancer cells in vitro and in vivo. Int J Oncol (2012) 0.93
A unified approach to the tedanolides: total synthesis of (+)-13-deoxytedanolide. Proc Natl Acad Sci U S A (2004) 0.92
Agonists of the follicle stimulating hormone receptor from an encoded thiazolidinone library. J Comb Chem (2004) 0.92
Blood donors' helping behavior is driven by warm glow: more evidence for the blood donor benevolence hypothesis. Transfusion (2012) 0.91
Object detection in the ring scotoma of a monocular bioptic telescope. Arch Ophthalmol (2011) 0.91
Effect of wrinkles on the surface area of graphene: toward the design of nanoelectronics. Nano Lett (2014) 0.91
Metabolomic-derived novel cyst fluid biomarkers for pancreatic cysts: glucose and kynurenine. Gastrointest Endosc (2013) 0.90
Exact epidemic models on graphs using graph-automorphism driven lumping. J Math Biol (2010) 0.90
Gene polymorphisms and periodontitis. Periodontol 2000 (2011) 0.89
Children and television tipovers: a significant and preventable cause of long-term neurological deficits. J Neurosurg (2005) 0.89
Regional areas and widths of the midsagittal corpus callosum among HIV-infected patients on stable antiretroviral therapies. J Neurovirol (2011) 0.88
Dynamic changes in Robo2 and Slit1 expression in adult rat dorsal root ganglion and sciatic nerve after peripheral and central axonal injury. Neurosci Res (2006) 0.88
Mass spectrometry compatible surfactant for optimized in-gel protein digestion. Anal Chem (2013) 0.88
Lipid rafts alter the stability and activity of the cholera toxin A1 subunit. J Biol Chem (2012) 0.87
Bioaugmentation as a solution to increase methane production from an ammonia-rich substrate. Environ Sci Technol (2014) 0.87
Integrated approaches for the public health prioritization of foodborne and zoonotic pathogens. Risk Anal (2009) 0.87
Magnetic resonance spectroscopic studies of alcoholism: from heavy drinking to alcohol dependence and back again. Alcohol Clin Exp Res (2005) 0.87
Tomato TFT1 is required for PAMP-triggered immunity and mutations that prevent T3S effector XopN from binding to TFT1 attenuate Xanthomonas virulence. PLoS Pathog (2012) 0.87
Efficient methods of nanoimprint stamp cleaning based on imprint self-cleaning effect. Nanotechnology (2011) 0.86
Structural and functional interactions between the cholera toxin A1 subunit and ERdj3/HEDJ, a chaperone of the endoplasmic reticulum. Infect Immun (2011) 0.86
Avian bornavirus is present in many tissues of psittacine birds with histopathologic evidence of proventricular dilatation disease. J Vet Diagn Invest (2010) 0.86
Screening and characterization of reactive metabolites using glutathione ethyl ester in combination with Q-trap mass spectrometry. J Mass Spectrom (2009) 0.86
Comparison of in vitro bioactivation of flutamide and its cyano analogue: evidence for reductive activation by human NADPH:cytochrome P450 reductase. Chem Res Toxicol (2008) 0.86
DEVELOPMENT AND EVALUATION OF VISION MULTIPLEXING DEVICES FOR VISION IMPAIRMENTS. Int J Artif Intell Tools (2009) 0.84
ADP-ribosylation factor 6 acts as an allosteric activator for the folded but not disordered cholera toxin A1 polypeptide. Mol Microbiol (2014) 0.84
Effect of the cytokine levels in serum on osteosarcoma. Tumour Biol (2013) 0.84
A benchmark dose analysis for sodium monofluoroacetate (1080) using dichotomous toxicity data. Regul Toxicol Pharmacol (2006) 0.84
Long Non-Coding RNA MEG3 Inhibits Cell Proliferation and Induces Apoptosis in Prostate Cancer. Cell Physiol Biochem (2015) 0.84
Construction of collagen II/hyaluronate/chondroitin-6-sulfate tri-copolymer scaffold for nucleus pulposus tissue engineering and preliminary analysis of its physico-chemical properties and biocompatibility. J Mater Sci Mater Med (2009) 0.83
Tuning inter-dot tunnel coupling of an etched graphene double quantum dot by adjacent metal gates. Sci Rep (2013) 0.83
Gold(III) macrocycles: nucleotide-specific unconventional catalytic inhibitors of human topoisomerase I. J Am Chem Soc (2014) 0.83
Notification and support for people exposed to the risk of Creutzfeldt-Jakob disease (CJD) (or other prion diseases) through medical treatment (iatrogenically). Cochrane Database Syst Rev (2011) 0.83
Breathing frequency bias in fractal analysis of heart rate variability. Biol Psychol (2009) 0.82
Optimization of biohydrogen and methane recovery within a cassava ethanol wastewater/waste integrated management system. Bioresour Technol (2012) 0.82
Efficient Execution Methods of Pivoting for Bulk Extraction of Entity-Attribute-Value-Modeled Data. IEEE J Biomed Health Inform (2015) 0.82