Published in Oncogene on July 02, 2012
Down-regulation of miR-675-5p contributes to tumor progression and development by targeting pro-tumorigenic GPR55 in non-small cell lung cancer. Mol Cancer (2015) 1.01
GPR55, a G-protein coupled receptor for lysophosphatidylinositol, plays a role in motor coordination. PLoS One (2013) 0.90
Identification of the GPR55 antagonist binding site using a novel set of high-potency GPR55 selective ligands. Biochemistry (2013) 0.88
Heteromerization of GPR55 and cannabinoid CB2 receptors modulates signalling. Br J Pharmacol (2014) 0.85
Targeting CB2-GPR55 receptor heteromers modulates cancer cell signaling. J Biol Chem (2014) 0.83
Cannabinoid receptor CB1 regulates STAT3 activity and its expression dictates the responsiveness to SR141716 treatment in human glioma patients' cells. Oncotarget (2015) 0.83
(R,R')-4'-methoxy-1-naphthylfenoterol targets GPR55-mediated ligand internalization and impairs cancer cell motility. Biochem Pharmacol (2013) 0.82
Hunting for the function of orphan GPCRs - beyond the search for the endogenous ligand. Br J Pharmacol (2014) 0.82
Minireview: ubiquitination-regulated G protein-coupled receptor signaling and trafficking. Mol Endocrinol (2013) 0.80
GPR55 promotes migration and adhesion of colon cancer cells indicating a role in metastasis. Br J Pharmacol (2015) 0.79
The therapeutic potential of orphan GPCRs, GPR35 and GPR55. Front Pharmacol (2015) 0.78
CB2 receptor activation inhibits melanoma cell transmigration through the blood-brain barrier. Int J Mol Sci (2014) 0.78
Activation of the orphan receptor GPR55 by lysophosphatidylinositol promotes metastasis in triple-negative breast cancer. Oncotarget (2016) 0.76
Deletion of Gpr55 Results in Subtle Effects on Energy Metabolism, Motor Activity and Thermal Pain Sensation. PLoS One (2016) 0.76
Orphan G protein receptor GPR55 as an emerging target in cancer therapy and management. Cancer Manag Res (2013) 0.76
Lysophosphatidylinositol Signalling and Metabolic Diseases. Metabolites (2016) 0.75
Molecular mechanisms of target recognition by lipid GPCRs: relevance for cancer. Oncogene (2015) 0.75
Design, synthesis, and analysis of antagonists of GPR55: Piperidine-substituted 1,3,4-oxadiazol-2-ones. Bioorg Med Chem Lett (2016) 0.75
G protein-coupled receptor GPR55 promotes colorectal cancer and has opposing effects to cannabinoid receptor 1. Int J Cancer (2017) 0.75
Concurrent activation of β2-adrenergic receptor and blockage of GPR55 disrupts pro-oncogenic signaling in glioma cells. Cell Signal (2017) 0.75
Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis. Nature (1986) 6.14
Vitamin D(3) promotes the differentiation of colon carcinoma cells by the induction of E-cadherin and the inhibition of beta-catenin signaling. J Cell Biol (2001) 3.44
Disease states associated with telomerase deficiency appear earlier in mice with short telomeres. EMBO J (1999) 3.29
Anti-tumoral action of cannabinoids: involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation. Nat Med (2000) 2.85
Increased epidermal tumors and increased skin wound healing in transgenic mice overexpressing the catalytic subunit of telomerase, mTERT, in basal keratinocytes. EMBO J (2001) 2.83
Correlation of E-cadherin expression with differentiation grade and histological type in breast carcinoma. Am J Pathol (1993) 2.74
Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis. Nat Genet (2000) 2.68
Restoration of telomerase activity rescues chromosomal instability and premature aging in Terc-/- mice with short telomeres. EMBO Rep (2001) 2.59
Evaluation of antibodies to hepatitis C virus in a study of transfusion-associated hepatitis. N Engl J Med (1990) 2.50
Tumor susceptibility of p21(Waf1/Cip1)-deficient mice. Cancer Res (2001) 2.37
Escitalopram (S-enantiomer of citalopram): clinical efficacy and onset of action predicted from a rat model. Pharmacol Toxicol (2001) 2.34
Leptin induces mitochondrial superoxide production and monocyte chemoattractant protein-1 expression in aortic endothelial cells by increasing fatty acid oxidation via protein kinase A. J Biol Chem (2001) 2.30
Limited overlapping roles of P15(INK4b) and P18(INK4c) cell cycle inhibitors in proliferation and tumorigenesis. EMBO J (2000) 2.21
A role for the E-cadherin cell-cell adhesion molecule during tumor progression of mouse epidermal carcinogenesis. J Cell Biol (1991) 2.18
[The radiologic manifestations of bronchiolitis obliterans]. Rev Clin Esp (1991) 1.99
v-ras genes from Harvey and BALB murine sarcoma viruses can act as initiators of two-stage mouse skin carcinogenesis. Cell (1986) 1.76
Comparison of the effects of antidepressants and their metabolites on reuptake of biogenic amines and on receptor binding. Cell Mol Neurobiol (1999) 1.56
Epicrania fugax: an ultrabrief paroxysmal epicranial pain. Cephalalgia (2008) 1.55
Identification of PA2.26 antigen as a novel cell-surface mucin-type glycoprotein that induces plasma membrane extensions and increased motility in keratinocytes. J Cell Sci (1999) 1.54
Solid- and vapor-phase antimicrobial activities of six essential oils: susceptibility of selected foodborne bacterial and fungal strains. J Agric Food Chem (2005) 1.51
The AMP-activated protein kinase prevents ceramide synthesis de novo and apoptosis in astrocytes. FEBS Lett (2001) 1.49
Inhibition of glioma growth in vivo by selective activation of the CB(2) cannabinoid receptor. Cancer Res (2001) 1.49
Short telomeres result in organismal hypersensitivity to ionizing radiation in mammals. J Exp Med (2000) 1.49
Skin and wound infection by rapidly growing mycobacteria: an unexpected complication of liposuction and liposculpture. The Venezuelan Collaborative Infectious and Tropical Diseases Study Group. Arch Dermatol (2000) 1.47
The pharmacological effect of citalopram residues in the (S)-(+)-enantiomer. J Neural Transm Gen Sect (1992) 1.47
The cell cycle inhibitor p21 controls T-cell proliferation and sex-linked lupus development. Nat Med (2000) 1.43
Adenosine monophosphate-activated protein kinase mediates the protective effects of ischemic preconditioning on hepatic ischemia-reperfusion injury in the rat. Hepatology (2001) 1.43
Risk factors for gastrointestinal complications in critically ill children with transpyloric enteral nutrition. Eur J Clin Nutr (2007) 1.43
Pharmacological effects of Lu AA21004: a novel multimodal compound for the treatment of major depressive disorder. J Pharmacol Exp Ther (2011) 1.42
Influence of atrial fibrillation on the morbido-mortality of patients on hemodialysis. Am Heart J (2000) 1.41
Snai1 and Snai2 collaborate on tumor growth and metastasis properties of mouse skin carcinoma cell lines. Oncogene (2008) 1.40
Induction of PA2.26, a cell-surface antigen expressed by active fibroblasts, in mouse epidermal keratinocytes during carcinogenesis. Mol Carcinog (1997) 1.38
[Anesthesiology and intensive care medicine]. Rev Esp Anestesiol Reanim (2004) 1.38
[The 2013 Seville Consensus Document on alternatives to allogenic blood transfusion. An update on the Seville Document]. Rev Esp Anestesiol Reanim (2013) 1.37
Delta9-tetrahydrocannabinol induces apoptosis in C6 glioma cells. FEBS Lett (1998) 1.37
Hybrid peptide-polyketide natural products: biosynthesis and prospects toward engineering novel molecules. Metab Eng (2001) 1.35
Early detection of PrPres in BSE-infected bovine PrP transgenic mice. Arch Virol (2003) 1.34
Molecular determinants of Akt-induced keratinocyte transformation. Oncogene (2006) 1.34
Tumorigenic activity of p21Waf1/Cip1 in thymic lymphoma. Oncogene (2006) 1.32
The orphan G protein-coupled receptor GPR55 promotes cancer cell proliferation via ERK. Oncogene (2010) 1.32
Anti-tumoral action of cannabinoids on hepatocellular carcinoma: role of AMPK-dependent activation of autophagy. Cell Death Differ (2011) 1.32
A single amino acid substitution in nonstructural protein 3A can mediate adaptation of foot-and-mouth disease virus to the guinea pig. J Virol (2001) 1.29
Involvement of the cAMP/protein kinase A pathway and of mitogen-activated protein kinase in the anti-proliferative effects of anandamide in human breast cancer cells. FEBS Lett (1999) 1.27
A pilot clinical study of Delta9-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme. Br J Cancer (2006) 1.24
Control of hepatic fatty acid oxidation by 5'-AMP-activated protein kinase involves a malonyl-CoA-dependent and a malonyl-CoA-independent mechanism. Arch Biochem Biophys (1997) 1.24
The CB1 cannabinoid receptor is coupled to the activation of protein kinase B/Akt. Biochem J (2000) 1.19
De novo-synthesized ceramide signals apoptosis in astrocytes via extracellular signal-regulated kinase. FASEB J (2000) 1.19
The CB(1) cannabinoid receptor is coupled to the activation of c-Jun N-terminal kinase. Mol Pharmacol (2000) 1.17
Inhibition of pRb phosphorylation and cell-cycle progression by a 20-residue peptide derived from p16CDKN2/INK4A. Curr Biol (1996) 1.17
Chronic exposure of cultured transformed mouse epidermal cells to transforming growth factor-beta 1 induces an epithelial-mesenchymal transdifferentiation and a spindle tumoral phenotype. Cell Growth Differ (1995) 1.16
Bioisosteres of arecoline: 1,2,3,6-tetrahydro-5-pyridyl-substituted and 3-piperidyl-substituted derivatives of tetrazoles and 1,2,3-triazoles. Synthesis and muscarinic activity. J Med Chem (1994) 1.16
Stability and freeze-drying of cyclosporine loaded poly(D,L lactide-glycolide) carriers. Eur J Pharm Sci (1999) 1.13
The AMP-activated protein kinase is involved in the regulation of ketone body production by astrocytes. J Neurochem (1999) 1.13
Characterization of two polyketide methyltransferases involved in the biosynthesis of the antitumor drug mithramycin by Streptomyces argillaceus. J Biol Chem (2000) 1.13
Up-regulation of vascular endothelial growth factor/vascular permeability factor in mouse skin carcinogenesis correlates with malignant progression state and activated H-ras expression levels. Cancer Res (1996) 1.13
Comparison between Haemophilus parasuis infection in colostrums-deprived and sow-reared piglets. Vet Microbiol (2004) 1.11
SPECT/CT imaging of oncolytic adenovirus propagation in tumours in vivo using the Na/I symporter as a reporter gene. Gene Ther (2007) 1.10
Changes in proteasome localization during the cell cycle. Eur J Cell Biol (1994) 1.10
p27Kip1 represses transcription by direct interaction with p130/E2F4 at the promoters of target genes. Oncogene (2011) 1.09
Dinucleosidasetetraphosphatase in rat liver and Artemia salina. Biochim Biophys Acta (1976) 1.08
Measurement of sigma chi c2 B(chi c2-->J/psi gamma)/sigma chi c1 B(chi c1 -->J/psi gamma) in pp collisions at square root s=1.96 TeV. Phys Rev Lett (2007) 1.07
The R-enantiomer of citalopram counteracts escitalopram-induced increase in extracellular 5-HT in the frontal cortex of freely moving rats. Neuropharmacology (2003) 1.06
Partial and full dopamine D1 receptor agonists in mice and rats: relation between behavioural effects and stimulation of adenylate cyclase activity in vitro. Eur J Pharmacol (1992) 1.05
Immunohistologic detection of estrogen receptor alpha in canine mammary tumors: clinical and pathologic associations and prognostic significance. Vet Pathol (2000) 1.05
Neuropsychological test scores, academic performance, and developmental disorders in Spanish-speaking children. Dev Neuropsychol (2001) 1.05
An oxidation domain in the BlmIII non-ribosomal peptide synthetase probably catalyzing thiazole formation in the biosynthesis of the anti-tumor drug bleomycin in Streptomyces verticillus ATCC15003. FEMS Microbiol Lett (2000) 1.05
[Detection of IgM against the dengue++ virus in whole blood absorbed on filter paper]. Rev Panam Salud Publica (1998) 1.05
Antitumor effectiveness of different amounts of electrical charge in Ehrlich and fibrosarcoma Sa-37 tumors. BMC Cancer (2004) 1.04
Characterisation of three Amerindian populations from Hidalgo State (Mexico) by 15 STR-PCR polymorphisms. Int J Legal Med (2004) 1.04
A new adjuvant improves the immune response to hepatitis B vaccine in hemodialysis patients. Kidney Int (2007) 1.03
Involvement of sphingomyelin hydrolysis and the mitogen-activated protein kinase cascade in the Delta9-tetrahydrocannabinol-induced stimulation of glucose metabolism in primary astrocytes. Mol Pharmacol (1998) 1.03
Carcinoma cell lines become sensitive to DNA-damaging agents by the expression of the adenovirus E1A gene. Oncogene (1996) 1.03
Control of the cell survival/death decision by cannabinoids. J Mol Med (Berl) (2001) 1.01
Involvement of the Ras/MAPK signaling pathway in the modulation of urokinase production and cellular invasiveness by transforming growth factor-beta(1) in transformed keratinocytes. Biochem Biophys Res Commun (2000) 1.00
Neonatal administration of the selective serotonin reuptake inhibitor Lu 10-134-C increases forced swimming-induced immobility in adult rats: a putative animal model of depression? J Pharmacol Exp Ther (1997) 1.00
Intracranial self-stimulation and sucrose intake differ as hedonic measures following chronic mild stress: interstrain and interindividual differences. Behav Brain Res (2000) 1.00
Evidence that the AMP-activated protein kinase stimulates rat liver carnitine palmitoyltransferase I by phosphorylating cytoskeletal components. FEBS Lett (1998) 1.00
Changes in keratin expression during malignant progression of transformed mouse epidermal keratinocytes. Exp Cell Res (1993) 1.00
Down-regulation of E-cadherin in mouse skin carcinoma cells enhances a migratory and invasive phenotype linked to matrix metalloproteinase-9 gelatinase expression. Lab Invest (1998) 1.00
Observation of Bs(0)-Bs(0) oscillations. Phys Rev Lett (2006) 1.00
Expression of simple epithelial cytokeratins in mouse epidermal keratinocytes harboring Harvey ras gene alterations. Cancer Res (1992) 1.00
Immunocytochemical demonstration of p21 ras family oncogene product in normal mucosa and in premalignant and malignant tumours of the colorectum. Br J Cancer (1985) 0.99
Freeze-drying of polycaprolactone and poly(D,L-lactic-glycolic) nanoparticles induce minor particle size changes affecting the oral pharmacokinetics of loaded drugs. Eur J Pharm Biopharm (2000) 0.98
Akt pathway as a target for therapeutic intervention in HNSCC. Histol Histopathol (2008) 0.97
Aberrant expression of the simple epithelial type II keratin 8 by mouse skin carcinomas but not papillomas. Mol Carcinog (1992) 0.96
Kaposi's sarcoma-like lesions and other nodules as cutaneous involvement in AIDS-related visceral leishmaniasis. Br J Dermatol (2000) 0.96
Comparison between cardiac output measured by the pulmonary arterial thermodilution technique and that measured by the femoral arterial thermodilution technique in a pediatric animal model. Pediatr Cardiol (2003) 0.96
Ectopic expression of PA2.26 antigen in epidermal keratinocytes leads to destabilization of adherens junctions and malignant progression. Lab Invest (2000) 0.95
A needleless closed system device (CLAVE) protects from intravascular catheter tip and hub colonization: a prospective randomized study. J Hosp Infect (2003) 0.95
Stimulation of the midkine/ALK axis renders glioma cells resistant to cannabinoid antitumoral action. Cell Death Differ (2011) 0.95
Measurement of the top-quark mass in all-hadronic decays in pp collisions at CDF II. Phys Rev Lett (2007) 0.95
Early neonatal sudden death or near death syndrome. An epidemiological study of 29 cases. Acta Paediatr (1994) 0.94
A porcine cell surface receptor identified by monoclonal antibodies to SWC3 is a member of the signal regulatory protein family and associates with protein-tyrosine phosphatase SHP-1. Tissue Antigens (2000) 0.94
Bovine tuberculosis and the endangered Iberian lynx. Emerg Infect Dis (2000) 0.94
Sigma ligands with subnanomolar affinity and preference for the sigma 2 binding site. 1. 3-(omega-aminoalkyl)-1H-indoles. J Med Chem (1995) 0.94
Recurrent left ventricular pseudoaneurysm: diagnosed by color-flow Doppler echocardiography. Tex Heart Inst J (1990) 0.94