Published in Nat Methods on July 01, 2012
Role of the extracellular matrix in regulating stem cell fate. Nat Rev Mol Cell Biol (2013) 2.09
The cancer glycocalyx mechanically primes integrin-mediated growth and survival. Nature (2014) 1.96
CLASPs link focal-adhesion-associated microtubule capture to localized exocytosis and adhesion site turnover. Nat Cell Biol (2014) 1.30
Force engages vinculin and promotes tumor progression by enhancing PI3K activation of phosphatidylinositol (3,4,5)-triphosphate. Cancer Res (2014) 1.21
Integration of actin dynamics and cell adhesion by a three-dimensional, mechanosensitive molecular clutch. Nat Cell Biol (2015) 1.08
Stressing the limits of focal adhesion mechanosensitivity. Curr Opin Cell Biol (2014) 1.05
Alternative mechanisms for talin to mediate integrin function. Curr Biol (2015) 0.94
Physical biology in cancer. 3. The role of cell glycocalyx in vascular transport of circulating tumor cells. Am J Physiol Cell Physiol (2013) 0.90
Talin determines the nanoscale architecture of focal adhesions. Proc Natl Acad Sci U S A (2015) 0.87
4Pi fluorescence detection and 3D particle localization with a single objective. Opt Express (2013) 0.84
Nanoscale architecture of cadherin-based cell adhesions. Nat Cell Biol (2016) 0.83
Spectrally coded optical nanosectioning (SpecON) with biocompatible metal-dielectric-coated substrates. Proc Natl Acad Sci U S A (2013) 0.81
Topography of Cells Revealed by Variable-Angle Total Internal Reflection Fluorescence Microscopy. Biophys J (2016) 0.77
Actin in action: imaging approaches to study cytoskeleton structure and function. Cells (2013) 0.77
Use of TIRF to Monitor T-Lymphocyte Membrane Dynamics with Submicrometer and Subsecond Resolution. Cell Mol Bioeng (2014) 0.76
Real-time fluorescence imaging with 20 nm axial resolution. Nat Commun (2015) 0.76
Axial super resolution topography of focal adhesion by confocal microscopy. Microsc Res Tech (2013) 0.76
Integrin-mediated traction force enhances paxillin molecular associations and adhesion dynamics that increase the invasiveness of tumor cells into a three-dimensional extracellular matrix. Mol Biol Cell (2017) 0.76
Axial superresolution via multiangle TIRF microscopy with sequential imaging and photobleaching. Proc Natl Acad Sci U S A (2016) 0.75
Visualizing mechanical modulation of nanoscale organization of cell-matrix adhesions. Integr Biol (Camb) (2016) 0.75
The microenvironment matters. Mol Biol Cell (2014) 0.75
Site-Specific Modulation of Charge Controls the Structure and Stimulus Responsiveness of Intrinsically Disordered Peptide Brushes. Langmuir (2016) 0.75
The 4D nucleome project. Nature (2017) 0.75
Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc Natl Acad Sci U S A (1992) 35.45
Cell adhesion: integrating cytoskeletal dynamics and cellular tension. Nat Rev Mol Cell Biol (2010) 7.27
Nanoscale architecture of integrin-based cell adhesions. Nature (2010) 5.88
Breaking the diffraction barrier: super-resolution imaging of cells. Cell (2010) 5.83
Interferometric fluorescent super-resolution microscopy resolves 3D cellular ultrastructure. Proc Natl Acad Sci U S A (2009) 5.31
Balancing forces: architectural control of mechanotransduction. Nat Rev Mol Cell Biol (2011) 3.87
A role for actin arcs in the leading-edge advance of migrating cells. Nat Cell Biol (2011) 2.68
Dual-objective STORM reveals three-dimensional filament organization in the actin cytoskeleton. Nat Methods (2012) 2.67
Stretchy proteins on stretchy substrates: the important elements of integrin-mediated rigidity sensing. Dev Cell (2010) 2.65
Cell-adhesion assays: fabrication of an E-cadherin substratum and isolation of lateral and Basal membrane patches. Methods Mol Biol (2005) 1.40
Variable incidence angle fluorescence interference contrast microscopy for z-imaging single objects. Biophys J (2005) 1.27
Imaging intracellular fluorescent proteins at nanometer resolution. Science (2006) 38.97
Tensional homeostasis and the malignant phenotype. Cancer Cell (2005) 19.30
Matrix crosslinking forces tumor progression by enhancing integrin signaling. Cell (2009) 14.40
Improving the photostability of bright monomeric orange and red fluorescent proteins. Nat Methods (2008) 8.41
A tense situation: forcing tumour progression. Nat Rev Cancer (2009) 7.80
The extracellular matrix: a dynamic niche in cancer progression. J Cell Biol (2012) 6.07
Advances in fluorescent protein technology. J Cell Sci (2007) 5.91
Nanoscale architecture of integrin-based cell adhesions. Nature (2010) 5.88
Rapid three-dimensional isotropic imaging of living cells using Bessel beam plane illumination. Nat Methods (2011) 5.68
Dual-color superresolution imaging of genetically expressed probes within individual adhesion complexes. Proc Natl Acad Sci U S A (2007) 5.36
Interferometric fluorescent super-resolution microscopy resolves 3D cellular ultrastructure. Proc Natl Acad Sci U S A (2009) 5.31
Optimized cassettes for fluorescent protein tagging in Saccharomyces cerevisiae. Yeast (2004) 5.26
The organizing principle: microenvironmental influences in the normal and malignant breast. Differentiation (2002) 4.64
A bright and photostable photoconvertible fluorescent protein. Nat Methods (2009) 4.50
Far-red fluorescent tags for protein imaging in living tissues. Biochem J (2009) 4.38
Mechanics, malignancy, and metastasis: the force journey of a tumor cell. Cancer Metastasis Rev (2009) 4.36
A genetically encoded tag for correlated light and electron microscopy of intact cells, tissues, and organisms. PLoS Biol (2011) 4.07
Balancing forces: architectural control of mechanotransduction. Nat Rev Mol Cell Biol (2011) 3.87
The tension mounts: mechanics meets morphogenesis and malignancy. J Mammary Gland Biol Neoplasia (2004) 3.54
Improving FRET dynamic range with bright green and red fluorescent proteins. Nat Methods (2012) 3.54
The extracellular matrix at a glance. J Cell Sci (2010) 3.37
Extracellular matrix degradation and remodeling in development and disease. Cold Spring Harb Perspect Biol (2011) 3.36
A bright monomeric green fluorescent protein derived from Branchiostoma lanceolatum. Nat Methods (2013) 3.32
Total synthesis of a functional designer eukaryotic chromosome. Science (2014) 3.31
Actomyosin-mediated cellular tension drives increased tissue stiffness and β-catenin activation to induce epidermal hyperplasia and tumor growth. Cancer Cell (2011) 3.19
Dynamic interplay between the collagen scaffold and tumor evolution. Curr Opin Cell Biol (2010) 2.79
Noninvasive imaging beyond the diffraction limit of 3D dynamics in thickly fluorescent specimens. Cell (2012) 2.72
The fluorescent protein palette: tools for cellular imaging. Chem Soc Rev (2009) 2.69
A role for actin arcs in the leading-edge advance of migrating cells. Nat Cell Biol (2011) 2.68
Fluorescent protein FRET pairs for ratiometric imaging of dual biosensors. Nat Methods (2008) 2.56
Three-dimensional context regulation of metastasis. Clin Exp Metastasis (2008) 2.49
Membrane expansion alleviates endoplasmic reticulum stress independently of the unfolded protein response. J Cell Biol (2009) 2.35
Nonlinear structured-illumination microscopy with a photoswitchable protein reveals cellular structures at 50-nm resolution. Proc Natl Acad Sci U S A (2011) 2.34
Video-rate nanoscopy using sCMOS camera-specific single-molecule localization algorithms. Nat Methods (2013) 2.28
Photoconversion in orange and red fluorescent proteins. Nat Methods (2009) 2.23
Mammary epithelial cell: influence of extracellular matrix composition and organization during development and tumorigenesis. Int J Biochem Cell Biol (2007) 2.12
Real-time imaging of discrete exocytic events mediating surface delivery of AMPA receptors. J Neurosci (2007) 2.05
HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype. J Clin Invest (2010) 2.00
MT1-MMP-dependent control of skeletal stem cell commitment via a β1-integrin/YAP/TAZ signaling axis. Dev Cell (2013) 1.95
Genetically encoded biosensors based on engineered fluorescent proteins. Chem Soc Rev (2009) 1.95
An improved cerulean fluorescent protein with enhanced brightness and reduced reversible photoswitching. PLoS One (2011) 1.93
Initial neurite outgrowth in Drosophila neurons is driven by kinesin-powered microtubule sliding. Curr Biol (2013) 1.93
Confined activation and subdiffractive localization enables whole-cell PALM with genetically expressed probes. Nat Methods (2011) 1.85
A neo-substrate that amplifies catalytic activity of parkinson's-disease-related kinase PINK1. Cell (2013) 1.84
A human breast cell model of preinvasive to invasive transition. Cancer Res (2008) 1.79
In situ force mapping of mammary gland transformation. Integr Biol (Camb) (2011) 1.78
Forcing form and function: biomechanical regulation of tumor evolution. Trends Cell Biol (2010) 1.77
Integrin clustering is driven by mechanical resistance from the glycocalyx and the substrate. PLoS Comput Biol (2009) 1.69
Autocrine laminin-5 ligates alpha6beta4 integrin and activates RAC and NFkappaB to mediate anchorage-independent survival of mammary tumors. J Cell Biol (2003) 1.67
Vinculin-actin interaction couples actin retrograde flow to focal adhesions, but is dispensable for focal adhesion growth. J Cell Biol (2013) 1.63
Multiscale modeling of form and function. Science (2009) 1.60
Modeling morphogenesis and oncogenesis in three-dimensional breast epithelial cultures. Annu Rev Pathol (2008) 1.55
Time-lapse two-color 3D imaging of live cells with doubled resolution using structured illumination. Proc Natl Acad Sci U S A (2012) 1.54
Tumor microenvironment and progression. J Surg Oncol (2011) 1.54
An enhanced monomeric blue fluorescent protein with the high chemical stability of the chromophore. PLoS One (2011) 1.51
Fluorescent proteins at a glance. J Cell Sci (2011) 1.51
Filamin A-beta1 integrin complex tunes epithelial cell response to matrix tension. Mol Biol Cell (2009) 1.47
Alpha 6 beta 4 integrin regulates keratinocyte chemotaxis through differential GTPase activation and antagonism of alpha 3 beta 1 integrin. J Cell Sci (2003) 1.45
Hue-shifted monomeric variants of Clavularia cyan fluorescent protein: identification of the molecular determinants of color and applications in fluorescence imaging. BMC Biol (2008) 1.45
Mitochondrial network size scaling in budding yeast. Science (2012) 1.44
Demystifying the effects of a three-dimensional microenvironment in tissue morphogenesis. Methods Cell Biol (2007) 1.43
The ultrastructure of MCF-10A acini. J Cell Physiol (2006) 1.42
A contractile and counterbalancing adhesion system controls the 3D shape of crawling cells. J Cell Biol (2014) 1.36
A physical sciences network characterization of non-tumorigenic and metastatic cells. Sci Rep (2013) 1.33
Selectivity mechanism of the nuclear pore complex characterized by single cargo tracking. Nature (2010) 1.33
Single-molecule superresolution imaging allows quantitative analysis of RAF multimer formation and signaling. Proc Natl Acad Sci U S A (2013) 1.27
Death in the third dimension: apoptosis regulation and tissue architecture. Curr Opin Genet Dev (2004) 1.26
Hypoxia-inducible factor regulates alphavbeta3 integrin cell surface expression. Mol Biol Cell (2005) 1.26
Improved blue, green, and red fluorescent protein tagging vectors for S. cerevisiae. PLoS One (2013) 1.25
Rac-GAP-dependent inhibition of breast cancer cell proliferation by {beta}2-chimerin. J Biol Chem (2005) 1.24
Intracellular protein interaction mapping with FRET hybrids. Proc Natl Acad Sci U S A (2006) 1.24
alpha6beta4 integrin activates Rac-dependent p21-activated kinase 1 to drive NF-kappaB-dependent resistance to apoptosis in 3D mammary acini. J Cell Sci (2007) 1.20
Rac-dependent cyclin D1 gene expression regulated by cadherin- and integrin-mediated adhesion. J Cell Sci (2008) 1.17
Stromally derived lysyl oxidase promotes metastasis of transforming growth factor-β-deficient mouse mammary carcinomas. Cancer Res (2013) 1.16
Collagen architecture in pregnancy-induced protection from breast cancer. J Cell Sci (2013) 1.12
Mechanism of neuronal versus endothelial cell uptake of Alzheimer's disease amyloid beta protein. PLoS One (2009) 1.10
Rapid disorganization of mechanically interacting systems of mammary acini. Proc Natl Acad Sci U S A (2013) 1.10
The fluorescent protein color palette. Curr Protoc Cell Biol (2007) 1.04
The membrane-associated protein, supervillin, accelerates F-actin-dependent rapid integrin recycling and cell motility. Traffic (2010) 1.04
Internalized gap junctions are degraded by autophagy. Autophagy (2012) 1.04
Effect of substrate stiffness and PDGF on the behavior of vascular smooth muscle cells: implications for atherosclerosis. J Cell Physiol (2010) 1.02
Fluorescent protein tracking and detection: fluorescent protein structure and color variants. Cold Spring Harb Protoc (2009) 1.02
G2 phase chromatin lacks determinants of replication timing. J Cell Biol (2010) 1.01
Automated screening of microtubule growth dynamics identifies MARK2 as a regulator of leading edge microtubules downstream of Rac1 in migrating cells. PLoS One (2012) 1.01
A monomeric photoconvertible fluorescent protein for imaging of dynamic protein localization. J Mol Biol (2010) 1.01
Highly stable loading of Mcm proteins onto chromatin in living cells requires replication to unload. J Cell Biol (2011) 1.00
CpG island tumor suppressor promoter methylation in non-BRCA-associated early mammary carcinogenesis. Cancer Epidemiol Biomarkers Prev (2009) 0.99
High-resolution imaging of cardiomyocyte behavior reveals two distinct steps in ventricular trabeculation. Development (2014) 0.99
Fluorescent proteins for FRET microscopy: monitoring protein interactions in living cells. Bioessays (2012) 0.99
SWI/SNF chromatin remodeling enzyme ATPases promote cell proliferation in normal mammary epithelial cells. J Cell Physiol (2010) 0.99
Analysis of protein expression during oxidative stress in breast epithelial cells using a stable isotope labeled proteome internal standard. J Proteome Res (2005) 0.99
Scaffold nucleoporins Nup188 and Nup192 share structural and functional properties with nuclear transport receptors. Elife (2013) 0.98
Growth cone-specific functions of XMAP215 in restricting microtubule dynamics and promoting axonal outgrowth. Neural Dev (2013) 0.96
mMaple: a photoconvertible fluorescent protein for use in multiple imaging modalities. PLoS One (2012) 0.96
Fluorescent protein tracking and detection: applications using fluorescent proteins in living cells. Cold Spring Harb Protoc (2009) 0.95
Monitoring protein interactions in living cells with fluorescence lifetime imaging microscopy. Methods Enzymol (2012) 0.95
Myosin II-mediated focal adhesion maturation is tension insensitive. PLoS One (2013) 0.93
Dual function of CD81 in influenza virus uncoating and budding. PLoS Pathog (2013) 0.92