Published in Comp Med on June 01, 2012
Role of estrogen in diastolic dysfunction. Am J Physiol Heart Circ Physiol (2014) 0.93
Estrogen therapy, independent of timing, improves cardiac structure and function in oophorectomized mRen2.Lewis rats. Menopause (2013) 0.87
Efficacy of female rat models in translational cardiovascular aging research. J Aging Res (2014) 0.77
Decreased bone mineral density in rats rendered follicle-deplete by an ovotoxic chemical correlates with changes in follicle-stimulating hormone and inhibin A. Calcif Tissue Int (2012) 0.76
Modeling menopause: The utility of rodents in translational behavioral endocrinology research. Maturitas (2016) 0.76
Parabens Accelerate Ovarian Dysfunction in a 4-Vinylcyclohexene Diepoxide-Induced Ovarian Failure Model. Int J Environ Res Public Health (2017) 0.75
Cognitive changes across the menopause transition: A longitudinal evaluation of the impact of age and ovarian status on spatial memory. Horm Behav (2016) 0.75
Are changes in cardiovascular disease risk factors in midlife women due to chronological aging or to the menopausal transition? J Am Coll Cardiol (2009) 3.63
The ovariectomized rat model of postmenopausal bone loss. Bone Miner (1991) 3.38
A population-based assessment of rates of bone loss at multiple skeletal sites: evidence for substantial trabecular bone loss in young adult women and men. J Bone Miner Res (2008) 2.76
The rodent estrous cycle: characterization of vaginal cytology and its utility in toxicological studies. Birth Defects Res B Dev Reprod Toxicol (2007) 2.60
Menopause and the metabolic syndrome: the Study of Women's Health Across the Nation. Arch Intern Med (2008) 2.32
Bone turnover across the menopause transition: correlations with inhibins and follicle-stimulating hormone. J Clin Endocrinol Metab (2006) 2.04
Expression of follicle-stimulating hormone receptor in tumor blood vessels. N Engl J Med (2010) 1.92
The effect of ovariectomy and estradiol replacement on brain-derived neurotrophic factor messenger ribonucleic acid expression in cortical and hippocampal brain regions of female Sprague-Dawley rats. Endocrinology (1995) 1.61
Osteoporosis: an age-related and gender-specific disease--a mini-review. Gerontology (2008) 1.57
The follicle-deplete mouse ovary produces androgen. Biol Reprod (2004) 1.45
Risk factors for ovarian cancer: an overview with emphasis on hormonal factors. J Toxicol Environ Health B Crit Rev (2008) 1.22
Ovotoxicity in female Fischer rats and B6 mice induced by low-dose exposure to three polycyclic aromatic hydrocarbons: comparison through calculation of an ovotoxic index. Toxicol Appl Pharmacol (2000) 1.21
Early effects of ovotoxicity induced by 4-vinylcyclohexene diepoxide in rats and mice. Reprod Toxicol (1999) 1.18
Hormonal changes during menopause. Maturitas (2009) 1.18
Efficacy and mechanism of action of turmeric supplements in the treatment of experimental arthritis. Arthritis Rheum (2006) 1.16
Long-term effects of ovarian follicular depletion in rats by 4-vinylcyclohexene diepoxide. Reprod Toxicol (2002) 1.15
Ovarian aging and menopause: current theories, hypotheses, and research models. Exp Biol Med (Maywood) (2005) 1.14
Comparison of skeletal effects of ovariectomy versus chemically induced ovarian failure in mice. J Bone Miner Res (2008) 1.11
Characterization of cyclicity and hormonal profile with impending ovarian failure in a novel chemical-induced mouse model of perimenopause. Comp Med (2005) 1.10
Reproductive senescence in female rats: a longitudinal study of individual differences in estrous cycles and behavior. Biol Reprod (1988) 1.10
Effect of duration of dosing on onset of ovarian failure in a chemical-induced mouse model of perimenopause. Menopause (2006) 1.08
Simultaneous optical coherence tomography and laser induced fluorescence imaging in rat model of ovarian carcinogenesis. Cancer Biol Ther (2010) 0.99
Involvement of the KIT/KITL signaling pathway in 4-vinylcyclohexene diepoxide-induced ovarian follicle loss in rats. Biol Reprod (2008) 0.99
Ovarian toxicity of 4-vinylcyclohexene diepoxide: a mechanistic model. Toxicol Pathol (2001) 0.97
Development of an animal model for ovotoxicity using 4-vinylcyclohexene: a case study. Birth Defects Res B Dev Reprod Toxicol (2007) 0.97
Bone loss across the menopausal transition. Ann N Y Acad Sci (2010) 0.97
Gender-specific characteristics of atherosclerosis in menopausal women: risk factors, clinical course and strategies for prevention. Climacteric (2007) 0.97
Effect of ovariectomy on cardiac gene expression: inflammation and changes in SOCS gene expression. Physiol Genomics (2007) 0.94
The menopausal transition--endocrinology. J Sex Med (2008) 0.94
Ovarian toxicity of 4-vinylcyclohexene and related olefins in B6C3F1 mice: role of diepoxides. Chem Res Toxicol (1996) 0.91
Persistent estrus rat models of polycystic ovary disease: an update. Fertil Steril (2005) 0.91
Implications of recent clinical trials of postmenopausal hormone therapy for management of cardiovascular disease. Ann N Y Acad Sci (2006) 0.89
Recent female mouse models displaying advanced reproductive aging. Exp Gerontol (2005) 0.88
Pattern of follicular growth and steroidogenesis in the ovary of aging cycling rats. Exp Aging Res (1979) 0.87
17beta-estradiol affords protection against 4-vinylcyclohexene diepoxide-induced ovarian follicle loss in Fischer-344 rats. Endocrinology (2002) 0.87
Management of obesity in menopause: diet, exercise, pharmacotherapy and bariatric surgery. Maturitas (2009) 0.86
Reproductive capacity of aging female rats. Neuroendocrinology (1975) 0.84
Effects of 4-vinylcyclohexene diepoxide on peripubertal and adult Sprague-Dawley rats: ovarian, clinical, and pathologic outcomes. Comp Med (2009) 0.79
Activin/follistatin and atherosclerosis--a review. J Atheroscler Thromb (1998) 0.79
TGFβ/activin signaling pathway activation in intimal hyperplasia and atherosclerosis. Diagn Interv Radiol (2010) 0.78
Comparison of the effects of the antiestrogens EM-800 and tamoxifen on the growth of human breast ZR-75-1 cancer xenografts in nude mice. Cancer Res (1998) 0.77
Neuroendocrinology of menopause. Minerva Ginecol (2006) 0.77
Current methods in investigating the development of the female reproductive system. Methods Mol Biol (2009) 0.76
Decreased bone mineral density in rats rendered follicle-deplete by an ovotoxic chemical correlates with changes in follicle-stimulating hormone and inhibin A. Calcif Tissue Int (2012) 0.76
Atherosclerotic lesion development in a novel ovary-intact mouse model of perimenopause. Arterioscler Thromb Vasc Biol (2005) 1.64
Destruction of primordial ovarian follicles in adult cynomolgus macaques after exposure to 4-vinylcyclohexene diepoxide: a nonhuman primate model of the menopausal transition. Fertil Steril (2006) 1.46
The follicle-deplete mouse ovary produces androgen. Biol Reprod (2004) 1.45
Characterization of a rat in vitro ovarian culture system to study the ovarian toxicant 4-vinylcyclohexene diepoxide. Toxicol Appl Pharmacol (2002) 1.29
Activation of mitogen-activated protein kinases and AP-1 transcription factor in ovotoxicity induced by 4-vinylcyclohexene diepoxide in rats. Biol Reprod (2002) 1.17
Long-term effects of ovarian follicular depletion in rats by 4-vinylcyclohexene diepoxide. Reprod Toxicol (2002) 1.15
Comparison of skeletal effects of ovariectomy versus chemically induced ovarian failure in mice. J Bone Miner Res (2008) 1.11
Differences between rats and mice in the involvement of the aryl hydrocarbon receptor in 4-vinylcyclohexene diepoxide-induced ovarian follicle loss. Toxicol Appl Pharmacol (2005) 1.10
Characterization of cyclicity and hormonal profile with impending ovarian failure in a novel chemical-induced mouse model of perimenopause. Comp Med (2005) 1.10
Effect of duration of dosing on onset of ovarian failure in a chemical-induced mouse model of perimenopause. Menopause (2006) 1.08
Skeletal muscle fat content is inversely associated with bone strength in young girls. J Bone Miner Res (2011) 1.06
Dual modality imaging of a novel rat model of ovarian carcinogenesis. J Biomed Opt (2006) 1.05
involvement of microsomal epoxide hydrolase enzyme in ovotoxicity caused by 7,12-dimethylbenz[a]anthracene. Toxicol Sci (2007) 1.03
Effect of phosphatidylinositol-3 kinase inhibition on ovotoxicity caused by 4-vinylcyclohexene diepoxide and 7, 12-dimethylbenz[a]anthracene in neonatal rat ovaries. Toxicol Appl Pharmacol (2009) 1.02
Expression and activity of cytochromes P450 2E1, 2A, and 2B in the mouse ovary: the effect of 4-vinylcyclohexene and its diepoxide metabolite. Toxicol Sci (2003) 1.01
Expression and activity of microsomal epoxide hydrolase in follicles isolated from mouse ovaries. Toxicol Sci (2002) 1.01
Involvement of the KIT/KITL signaling pathway in 4-vinylcyclohexene diepoxide-induced ovarian follicle loss in rats. Biol Reprod (2008) 0.99
Simultaneous optical coherence tomography and laser induced fluorescence imaging in rat model of ovarian carcinogenesis. Cancer Biol Ther (2010) 0.99
Drinking water with uranium below the U.S. EPA water standard causes estrogen receptor-dependent responses in female mice. Environ Health Perspect (2007) 0.98
Hormonal status affects the progression of STZ-induced diabetes and diabetic renal damage in the VCD mouse model of menopause. Am J Physiol Renal Physiol (2007) 0.97
Expression of ovarian microsomal epoxide hydrolase and glutathione S-transferase during onset of VCD-induced ovotoxicity in B6C3F(1) mice. Toxicol Appl Pharmacol (2008) 0.96
Initiation of delayed ovotoxicity by in vitro and in vivo exposures of rat ovaries to 4-vinylcyclohexene diepoxide. Reprod Toxicol (2004) 0.96
Effects of impending ovarian failure induced by 4-vinylcyclohexene diepoxide on fertility in C57BL/6 female mice. Comp Med (2007) 0.95
NTP-CERHR expert panel report on the reproductive and developmental toxicity of genistein. Birth Defects Res B Dev Reprod Toxicol (2006) 0.95
Evaluation of ovotoxicity induced by 7, 12-dimethylbenz[a]anthracene and its 3,4-diol metabolite utilizing a rat in vitro ovarian culture system. Toxicol Appl Pharmacol (2008) 0.94
Analysis of second-harmonic-generation microscopy in a mouse model of ovarian carcinoma. J Biomed Opt (2012) 0.94
Hexavalent chromium-induced apoptosis of granulosa cells involves selective sub-cellular translocation of Bcl-2 members, ERK1/2 and p53. Toxicol Appl Pharmacol (2011) 0.93
Loss of ovarian function in the VCD mouse-model of menopause leads to insulin resistance and a rapid progression into the metabolic syndrome. Am J Physiol Regul Integr Comp Physiol (2009) 0.92
Involvement of CYP 2E1 enzyme in ovotoxicity caused by 4-vinylcyclohexene and its metabolites. Toxicol Appl Pharmacol (2007) 0.92
Xenobiotic effects on ovarian preantral follicles. Biol Reprod (2011) 0.91
NTP-CERHR expert panel report on the reproductive and developmental toxicity of soy formula. Birth Defects Res B Dev Reprod Toxicol (2006) 0.90
Dual protective role for glutathione S-transferase class pi against VCD-induced ovotoxicity in the rat ovary. Toxicol Appl Pharmacol (2010) 0.90
In vitro ovarian tissue and organ culture: a review. Front Biosci (2002) 0.89
Exaggerated neutrophil-mediated reperfusion injury after ischemic stroke in a rodent model of type 2 diabetes. Microcirculation (2011) 0.89
Hibiscus sabdariffa L. in the treatment of hypertension and hyperlipidemia: a comprehensive review of animal and human studies. Fitoterapia (2013) 0.88
The effect of diet and cardiovascular risk on ovarian aging in cynomolgus monkeys (Macaca fascicularis). Menopause (2010) 0.88
Experimental induction of reduced ovarian reserve in a nonhuman primate model (Macaca fascicularis). Comp Med (2010) 0.88
Inhibition of PIK3 signaling pathway members by the ovotoxicant 4-vinylcyclohexene diepoxide in rats. Biol Reprod (2010) 0.87
17beta-estradiol affords protection against 4-vinylcyclohexene diepoxide-induced ovarian follicle loss in Fischer-344 rats. Endocrinology (2002) 0.87
Steroidogenic capacity of residual ovarian tissue in 4-vinylcyclohexene diepoxide-treated mice. Biol Reprod (2008) 0.87
Serum antimüllerian hormone predicts ovarian reserve in a monkey model. Menopause (2009) 0.87
Effect of CYP2E1 gene deletion in mice on expression of microsomal epoxide hydrolase in response to VCD exposure. Toxicol Sci (2008) 0.86
Curcuminoids block TGF-β signaling in human breast cancer cells and limit osteolysis in a murine model of breast cancer bone metastasis. J Nat Prod (2012) 0.85
Behavioral consequences of ovarian atrophy and estrogen replacement in the APPswe mouse. Neurobiol Aging (2007) 0.85
Ovarian expressed microsomal epoxide hydrolase: role in detoxification of 4-vinylcyclohexene diepoxide and regulation by phosphatidylinositol-3 kinase signaling. Toxicol Appl Pharmacol (2011) 0.84
Protection of trabecular bone in ovariectomized rats by turmeric (Curcuma longa L.) is dependent on extract composition. J Agric Food Chem (2010) 0.83
7,12-dimethylbenz[a]anthracene-induced malignancies in a mouse model of menopause. Comp Med (2013) 0.83
4-vinylcyclohexene diepoxide: a model chemical for ovotoxicity. Syst Biol Reprod Med (2012) 0.83
Glutathione S-transferase class μ regulation of apoptosis signal-regulating kinase 1 protein during VCD-induced ovotoxicity in neonatal rat ovaries. Toxicol Appl Pharmacol (2012) 0.82
7,12-dimethylbenz[a]anthracene induces sertoli-leydig-cell tumors in the follicle-depleted ovaries of mice treated with 4-vinylcyclohexene diepoxide. Comp Med (2010) 0.82
Distribution and responsiveness of rat anti-Müllerian hormone during ovarian development and VCD-induced ovotoxicity. Toxicol Appl Pharmacol (2010) 0.81
BAX is involved in regulating follicular growth, but is dispensable for follicle atresia in adult mouse ovaries. Reproduction (2007) 0.80
A longitudinal study of the effect of genistein on bone in two different murine models of diminished estrogen-producing capacity. J Osteoporos (2009) 0.80
Bioactivity of turmeric-derived curcuminoids and related metabolites in breast cancer. Curr Pharm Des (2013) 0.80
Two-photon excited fluorescence imaging of endogenous contrast in a mouse model of ovarian cancer. Lasers Surg Med (2013) 0.80
Inhibition of ovarian KIT phosphorylation by the ovotoxicant 4-vinylcyclohexene diepoxide in rats. Biol Reprod (2011) 0.79
Effects of 4-vinylcyclohexene diepoxide on peripubertal and adult Sprague-Dawley rats: ovarian, clinical, and pathologic outcomes. Comp Med (2009) 0.79
Midkine, a heparin-binding protein, is increased in the diabetic mouse kidney postmenopause. Am J Physiol Renal Physiol (2010) 0.78
4-Vinylcyclohexene diepoxide (VCD) inhibits mammary epithelial differentiation and induces fibroadenoma formation in female Sprague Dawley rats. Reprod Toxicol (2011) 0.77
mdr1a deficiency corrects sterility in Niemann-Pick C1 protein deficient female mice. Mol Reprod Dev (2002) 0.77
Effect of bcl-2 overexpression in mice on ovotoxicity caused by 4-vinylcyclohexene. Toxicol Appl Pharmacol (2006) 0.76
Current methods in investigating the development of the female reproductive system. Methods Mol Biol (2009) 0.76
Multidetector computed tomographic morphology of ovaries in cynomolgus macaques (Macaca fascicularis). J Am Assoc Lab Anim Sci (2007) 0.76
Retaining Residual Ovarian Tissue following Ovarian Failure Has Limited Influence on Bone Loss in Aged Mice. J Osteoporos (2010) 0.75
COMPROMISED FERTILITY IN FREE FEEDING OF WILD-CAUGHT NORWAY RATS (RATTUS NORVEGICUS) WITH A LIQUID BAIT CONTAINING 4-VINYLCYCLOHEXENE DIEPOXIDE AND TRIPTOLIDE. J Zoo Wildl Med (2017) 0.75
17β-Estradiol Affords Protection against 4-Vinylcyclohexene Diepoxide-Induced Ovarian Follicle Loss in Fischer-344 Rats. Endocrinology (2002) 0.75