Serum markers lactate dehydrogenase and S100B predict independently disease outcome in melanoma patients with distant metastasis.

PubWeight™: 1.19‹?› | Rank: Top 10%

🔗 View Article (PMC 3405231)

Published in Br J Cancer on July 10, 2012

Authors

B Weide1, M Elsässer, P Büttner, A Pflugfelder, U Leiter, T K Eigentler, J Bauer, M Witte, F Meier, C Garbe

Author Affiliations

1: Department of Dermatology, Center for Dermatooncology, University Medical Center, Liebermeisterstrasse 25, Tübingen 72076, Germany. benjamin.weide@med.uni-tuebingen.de

Articles citing this

JQ1 suppresses tumor growth through downregulating LDHA in ovarian cancer. Oncotarget (2015) 1.01

Diagnostic and prognostic biomarkers in melanoma. J Clin Aesthet Dermatol (2014) 0.98

Serum S100B, lactate dehydrogenase and brain metastasis are prognostic factors in patients with distant melanoma metastasis and systemic therapy. PLoS One (2013) 0.97

The evolution of S100B inhibitors for the treatment of malignant melanoma. Future Med Chem (2013) 0.91

Prognostic value of pretreatment serum lactate dehydrogenase level in patients with solid tumors: a systematic review and meta-analysis. Sci Rep (2015) 0.89

Phase II trial of vatalanib in patients with advanced or metastatic pancreatic adenocarcinoma after first-line gemcitabine therapy (PCRT O4-001). Cancer Chemother Pharmacol (2014) 0.87

Serum lactate dehydrogenase as an early marker for outcome in patients treated with anti-PD-1 therapy in metastatic melanoma. Br J Cancer (2016) 0.87

Melanoma patients with unknown primary site or nodal recurrence after initial diagnosis have a favourable survival compared to those with synchronous lymph node metastasis and primary tumour. PLoS One (2013) 0.85

The Prognostic and Predictive Value of Melanoma-related MicroRNAs Using Tissue and Serum: A MicroRNA Expression Analysis. EBioMedicine (2015) 0.84

Influence of (18)F-FDG PET/CT on therapy management in patients with stage III/IV malignant melanoma. Eur J Nucl Med Mol Imaging (2015) 0.84

Lactate Dehydrogenase Is an Important Prognostic Indicator for Hepatocellular Carcinoma after Partial Hepatectomy. Transl Oncol (2015) 0.83

Serum lactate dehydrogenase and survival following cancer diagnosis. Br J Cancer (2015) 0.82

Prognostic factors of melanoma patients with satellite or in-transit metastasis at the time of stage III diagnosis. PLoS One (2013) 0.82

Future perspectives in melanoma research: meeting report from the "Melanoma Bridge", Napoli, December 5th-8th 2013. J Transl Med (2014) 0.80

Targeting metabolic flexibility by simultaneously inhibiting respiratory complex I and lactate generation retards melanoma progression. Oncotarget (2015) 0.79

Improvement of overall survival in stage IV melanoma patients during 2011-2014: analysis of real-world data in 441 patients of the German Central Malignant Melanoma Registry (CMMR). J Cancer Res Clin Oncol (2016) 0.78

Chinese Guidelines on the Diagnosis and Treatment of Melanoma (2015 Edition). Ann Transl Med (2015) 0.76

SERPINB1 expression is predictive for sensitivity and outcome of cisplatin-based chemotherapy in melanoma. Oncotarget (2016) 0.75

Serum lactate dehydrogenase predicts prognosis and correlates with systemic inflammatory response in patients with advanced pancreatic cancer after gemcitabine-based chemotherapy. Sci Rep (2017) 0.75

Study protocol for a prospective, non-controlled, multicentre clinical study to evaluate the diagnostic accuracy of a stepwise two-photon excited melanin fluorescence in pigmented lesions suspicious for melanoma (FLIMMA study). BMJ Open (2016) 0.75

Selected patients can benefit more from the management of etoposide and platinum-based chemotherapy and thoracic irradiation-a retrospective analysis of 707 small cell lung cancer patients. Oncotarget (2016) 0.75

The Melanoma MAICare Framework: A Microsimulation Model for the Assessment of Individualized Cancer Care. Cancer Inform (2016) 0.75

Soluble NKG2D ligands are biomarkers associated with the clinical outcome to immune checkpoint blockade therapy of metastatic melanoma patients. Oncoimmunology (2017) 0.75

Impact of (18)F-FDG-PET/CT on surgical management in patients with advanced melanoma: an outcome based analysis. Eur J Nucl Med Mol Imaging (2017) 0.75

Articles cited by this

Final version of 2009 AJCC melanoma staging and classification. J Clin Oncol (2009) 23.08

Final version of the American Joint Committee on Cancer staging system for cutaneous melanoma. J Clin Oncol (2001) 9.68

S100: a multigenic family of calcium-modulated proteins of the EF-hand type with intracellular and extracellular functional roles. Int J Biochem Cell Biol (2001) 5.29

NDR kinases regulate essential cell processes from yeast to humans. Nat Rev Mol Cell Biol (2006) 2.88

Prognostic factors in metastatic melanoma: a pooled analysis of Eastern Cooperative Oncology Group trials. J Clin Oncol (2000) 2.86

Surgical resection for melanoma metastatic to the gastrointestinal tract. Arch Surg (1996) 1.91

A single-institution validation of the AJCC staging system for stage IV melanoma. Ann Surg Oncol (2008) 1.64

Stage-IV melanoma and pulmonary metastases: factors predictive of survival. Ann Surg Oncol (2007) 1.63

Lung metastases from melanoma: when is surgical treatment warranted? Br J Cancer (2000) 1.61

Predicting survival outcome of localized melanoma: an electronic prediction tool based on the AJCC Melanoma Database. Ann Surg Oncol (2010) 1.59

Does complete resection of melanoma metastatic to solid intra-abdominal organs improve survival? Ann Surg Oncol (2001) 1.57

Prognostic factors in patients with metastatic malignant melanoma. A multivariate analysis. Cancer (1993) 1.52

Contemporary surgical treatment of advanced-stage melanoma. Arch Surg (2004) 1.52

S100-Beta, melanoma-inhibiting activity, and lactate dehydrogenase discriminate progressive from nonprogressive American Joint Committee on Cancer stage IV melanoma. J Clin Oncol (1999) 1.49

Complete metastasectomy in patients with stage IV metastatic melanoma. Lancet Oncol (2006) 1.33

Prognostic factors for survival of patients treated systemically for disseminated melanoma. J Clin Oncol (1998) 1.29

Does metastasectomy improve survival in patients with Stage IV melanoma? A cancer registry analysis of outcomes. J Surg Oncol (2011) 1.29

Surgical therapy for distant metastases of malignant melanoma. Cancer (2000) 1.20

Prognostic significance of serum S100B protein in high-risk surgically resected melanoma patients participating in Intergroup Trial ECOG 1694. J Clin Oncol (2008) 1.19

Improvement of overall survival of patients with cutaneous melanoma in Germany, 1976-2001: which factors contributed? Cancer (2007) 1.17

Active secretion of S100B from astrocytes during metabolic stress. Neuroscience (2006) 1.05

Elevated serum levels of the glial marker protein S100B are not specific for schizophrenia or mood disorders. Mol Psychiatry (2009) 1.05

Evidence and interdisciplinary consense-based German guidelines: diagnosis and surveillance of melanoma. Melanoma Res (2007) 1.04

Prognostic significance of serum S100B detection compared with routine blood parameters in advanced metastatic melanoma patients. Melanoma Res (1999) 1.00

Gender and other survival predictors in patients with metastatic melanoma on Southwest Oncology Group trials. Cancer (2001) 0.97

LDH and melanoma. Cancer (1983) 0.96

Evidence and interdisciplinary consensus-based German guidelines: surgical treatment and radiotherapy of melanoma. Melanoma Res (2008) 0.95

Normal values of serum S-100B predict prolonged survival for stage IV melanoma patients. Eur J Cancer (2005) 0.91

Serum S100beta protein as a marker of disease activity in patients with malignant melanoma. Med Oncol (2001) 0.90

S-100 protein-negative malignant melanoma: fact or fiction? A light-microscopic and immunohistochemical study. Am J Dermatopathol (1994) 0.90

Regression analyses of prognostic factors in metastatic malignant melanoma. Eur J Cancer Clin Oncol (1989) 0.89

Tyrosinase messenger RNA in peripheral blood is related to poor survival in patients with metastatic melanoma following interleukin-2-based immunotherapy. Melanoma Res (2005) 0.88

Long-term survival analysis in metastatic melanoma: serum S100B is an independent prognostic marker and superior to LDH. Onkologie (2008) 0.85

Articles by these authors

Inflammation and Alzheimer's disease. Neurobiol Aging (2000) 12.56

Cyclosporine in severe ulcerative colitis refractory to steroid therapy. N Engl J Med (1994) 6.05

Gait speed at usual pace as a predictor of adverse outcomes in community-dwelling older people an International Academy on Nutrition and Aging (IANA) Task Force. J Nutr Health Aging (2009) 5.98

A tunable topological insulator in the spin helical Dirac transport regime. Nature (2009) 4.98

A critical discussion of intraclass correlation coefficients. Stat Med (1995) 4.13

Observation of unconventional quantum spin textures in topological insulators. Science (2009) 3.58

Topological phase transition and texture inversion in a tunable topological insulator. Science (2011) 2.68

Interpreting DNA fingerprint clusters of Mycobacterium tuberculosis. European Concerted Action on Molecular Epidemiology and Control of Tuberculosis. Int J Tuberc Lung Dis (1999) 2.66

Dermcidin: a novel human antibiotic peptide secreted by sweat glands. Nat Immunol (2001) 2.29

Risk of Mycobacterium tuberculosis transmission in a low-incidence country due to immigration from high-incidence areas. J Clin Microbiol (2001) 2.24

Human melanoma progression in skin reconstructs : biological significance of bFGF. Am J Pathol (2000) 2.23

Observation of time-reversal-protected single-dirac-cone topological-insulator states in Bi2Te3 and Sb2Te3. Phys Rev Lett (2009) 2.22

Myopic children show insufficient accommodative response to blur. Invest Ophthalmol Vis Sci (1993) 2.08

Recombinant human B cell stimulatory factor 2 (BSF-2/IFN-beta 2) regulates beta-fibrinogen and albumin mRNA levels in Fao-9 cells. FEBS Lett (1987) 2.04

Successful treatment of severe refractory atopic dermatitis with mycophenolate mofetil. Br J Dermatol (1999) 1.96

Oncogenic GNAQ mutations are not correlated with disease-free survival in uveal melanoma. Br J Cancer (2009) 1.93

T- and B-cell responses to myelin oligodendrocyte glycoprotein in experimental autoimmune encephalomyelitis and multiple sclerosis. Glia (2001) 1.91

Transfusion medicine monitoring practices. A study of the College of American Pathologists/Centers for Disease Control and Prevention Outcomes Working Group. Arch Pathol Lab Med (1995) 1.87

B lymphocytes producing demyelinating autoantibodies: development and function in gene-targeted transgenic mice. J Exp Med (1998) 1.85

Relation of the course of HIV infection in children to the severity of the disease in their mothers at delivery. N Engl J Med (1994) 1.85

IS1245 restriction fragment length polymorphism typing of Mycobacterium avium isolates: proposal for standardization. J Clin Microbiol (1998) 1.80

Awareness and early detection of cutaneous melanoma: an analysis of factors related to delay in treatment. Br J Dermatol (1999) 1.79

Effects of cytokines on the liver. Hepatology (1991) 1.76

Metastatic pathways and time courses in the orderly progression of cutaneous melanoma. Br J Dermatol (2002) 1.71

Problems in defining cutoff points of continuous prognostic factors: example of tumor thickness in primary cutaneous melanoma. J Clin Epidemiol (1997) 1.69

Predictors of MCAT scores for black Americans. J Natl Med Assoc (1987) 1.68

Transverse-momentum and pseudorapidity distributions of charged hadrons in pp collisions at square root of s = 7 TeV. Phys Rev Lett (2010) 1.67

The dermatoscopic pattern of clear-cell acanthoma resembles psoriasis vulgaris. Dermatology (2001) 1.66

Increase of melanocytic nevus counts in children during 5 years of follow-up and analysis of associated factors. Arch Dermatol (1996) 1.65

On the association between valproate and polycystic ovary syndrome. Epilepsia (2001) 1.65

TNF-alpha opens a paracellular route for HIV-1 invasion across the blood-brain barrier. Mol Med (1997) 1.65

Cleavage of zearalenone-glycoside, a "masked" mycotoxin, during digestion in swine. Zentralbl Veterinarmed B (1990) 1.64

Effect of a protein and energy dense N-3 fatty acid enriched oral supplement on loss of weight and lean tissue in cancer cachexia: a randomised double blind trial. Gut (2003) 1.62

Oligodendrocyte apoptosis and primary demyelination induced by local TNF/p55TNF receptor signaling in the central nervous system of transgenic mice: models for multiple sclerosis with primary oligodendrogliopathy. Am J Pathol (1998) 1.62

Metastatic melanoma of unknown primary origin shows prognostic similarities to regional metastatic melanoma: recommendations for initial staging examinations. Cancer (1997) 1.59

Erythrocyte K-Cl cotransport: properties and regulation. Am J Physiol (1992) 1.56

Detection of melanoma cells in sentinel lymph nodes, bone marrow and peripheral blood by a reverse transcription-polymerase chain reaction assay in patients with primary cutaneous melanoma: association with Breslow's tumour thickness. Br J Dermatol (2001) 1.56

Study of the mass and spin-parity of the Higgs boson candidate via its decays to Z boson pairs. Phys Rev Lett (2013) 1.56

Human papillomaviruses are commonly found in normal skin of immunocompetent hosts. J Invest Dermatol (1998) 1.54

The neuropeptide substance P activates transcription factor NF-kappa B and kappa B-dependent gene expression in human astrocytoma cells. J Immunol (1997) 1.52

Urine culture contamination: a College of American Pathologists Q-Probes study of contaminated urine cultures in 906 institutions. Arch Pathol Lab Med (1998) 1.50

Dermoscopic classification of atypical melanocytic nevi (Clark nevi). Arch Dermatol (2001) 1.49

Combined targeting of MAPK and AKT signalling pathways is a promising strategy for melanoma treatment. Br J Dermatol (2007) 1.49

Multidimensional assessment of personality in patients with psychogenic non-epileptic seizures. J Neurol Neurosurg Psychiatry (2004) 1.48

Epidemiologic evidence for the role of melanocytic nevi as risk markers and direct precursors of cutaneous malignant melanoma. Results of a case control study in melanoma patients and nonmelanoma control subjects. J Am Acad Dermatol (1992) 1.47

TNFR1 signalling is critical for the development of demyelination and the limitation of T-cell responses during immune-mediated CNS disease. Brain (2000) 1.47

Diagnostic delay in psychogenic nonepileptic seizures. Neurology (2002) 1.45

Asymmetric repair of bacteriophage T7 heteroduplex DNA. Mol Gen Genet (1981) 1.44

Targeting of an abundant cytosolic form of the protein import receptor at Toc159 to the outer chloroplast membrane. J Cell Biol (2001) 1.44

Basal cell carcinoma: histological classification and body-site distribution. Br J Dermatol (2006) 1.43

Imaging the Fano lattice to 'hidden order' transition in URu(2)Si(2). Nature (2010) 1.42

Determination of the X(3872) meson quantum numbers. Phys Rev Lett (2013) 1.42

Hot topic: Bovine milk samples yielding negative or nonspecific results in bacterial culturing--the possible role of PCR-single strand conformation polymorphism in mastitis diagnosis. J Dairy Sci (2012) 1.42

[Chronic fatigue syndrome. Definition, diagnostic measures and therapeutic possibilities]. Nervenarzt (1996) 1.42

Effects of intralipid infusion on blood viscosity and other haemorheological parameters in neonates and children. Acta Paediatr (2004) 1.41

Interleukin-6-(IL-6) plasma levels in depression and schizophrenia: comparison between the acute state and after remission. Eur Arch Psychiatry Clin Neurosci (1997) 1.41

The greater acceptance and utilization of nurse practitioners. Am J Manag Care (2001) 1.39

[Elective lymph node dissection in primary malignant melanoma]. Hautarzt (1996) 1.39

Increased high-density lipoprotein cholesterol in patients with epilepsy treated with carbamazepine: a gender-related study. Epilepsia (1999) 1.39

Changes in enteric neurone phenotype and intestinal functions in a transgenic mouse model of enteric glia disruption. Gut (2005) 1.39

[Correlation between chronic hyperplastic laryngitis and infection with human papillomaviruses]. HNO (1993) 1.38

[Merkel cell tumor of the skin]. Dtsch Med Wochenschr (1997) 1.38

Oral hairy leukoplakia in 71 HIV-seropositive patients: clinical symptoms, relation to immunologic status, and prognostic significance. J Am Acad Dermatol (1996) 1.38

Effect of educational level, gender and age on the performance in a multi-user computerized psychometric test system for use in clinical pharmacological studies. Arzneimittelforschung (1996) 1.38

High incidence of central nervous system involvement in patients with metastatic or locally advanced breast cancer treated with epirubicin and docetaxel. Ann Oncol (2001) 1.38

Direct binding to and tyrosine phosphorylation of the alpha subunit of the type I interferon receptor by p135tyk2 tyrosine kinase. Mol Cell Biol (1994) 1.37

Perforated appendicitis within an inguinal hernia: case report and review of the literature. Am J Gastroenterol (1997) 1.37

Nationwide linkage analysis in Scotland to assess mortality following hospital admission for Crohn's disease: 1998-2000. Aliment Pharmacol Ther (2011) 1.37

Determinants of survival in patients with brain metastases from cutaneous melanoma. Br J Cancer (2010) 1.37

Outcomes of cryosurgery in keloids and hypertrophic scars. A prospective consecutive trial of case series. Arch Dermatol (1993) 1.36

Prefrontal cortical hypometabolism during low-dose interferon alpha treatment. Psychopharmacology (Berl) (2000) 1.35

Development of a valid and reliable malnutrition screening tool for adult acute hospital patients. Nutrition (1999) 1.34

Monkeypox virus in relation to the ecological features surrounding human settlements in Bumba zone, Zaire. Trop Geogr Med (1987) 1.33

Growth and relaxation processes in Ge nanocrystals on free-standing Si(001) nanopillars. Nanotechnology (2012) 1.32

The scored Patient-generated Subjective Global Assessment (PG-SGA) and its association with quality of life in ambulatory patients receiving radiotherapy. Eur J Clin Nutr (2003) 1.31

Risk factors for developing cutaneous melanoma and criteria for identifying persons at risk: multicenter case-control study of the Central Malignant Melanoma Registry of the German Dermatological Society. J Invest Dermatol (1994) 1.31

Queuosine modification of the wobble base in tRNAHis influences 'in vivo' decoding properties. EMBO J (1985) 1.30

Medical decompression of toxic megacolon by "rolling". A new technique of decompression with favorable long-term follow-up. J Clin Gastroenterol (1988) 1.30

Acral cutaneous melanoma in caucasians: clinical features, histopathology and prognosis in 112 patients. Br J Dermatol (2000) 1.29

Detection of interleukin-6 and alpha 2-macroglobulin immunoreactivity in cortex and hippocampus of Alzheimer's disease patients. Lab Invest (1992) 1.28

Cloning and expression of a long form of the beta subunit of the interferon alpha beta receptor that is required for signaling. J Biol Chem (1995) 1.27

Cocaine enhances monocyte migration across the blood-brain barrier. Cocaine's connection to AIDS dementia and vasculitis? Adv Exp Med Biol (1998) 1.27

Melanocytes in nevi and melanomas synthesize basement membrane and basement membrane-like material. An immunohistochemical and electron microscopic study including immunoelectron microscopy. J Cutan Pathol (2000) 1.27

Induction of an interleukin-1 receptor (IL-1R) on monocytic cells. Evidence that the receptor is not encoded by a T cell-type IL-1R mRNA. J Biol Chem (1990) 1.26

Scatter factor promotes motility of human glioma and neuromicrovascular endothelial cells. Int J Cancer (1998) 1.26

Serotonergic genes modulate amygdala activity in major depression. Genes Brain Behav (2006) 1.25

Amyloid-beta induces chemokine secretion and monocyte migration across a human blood--brain barrier model. Mol Med (1998) 1.25

A dynamic relationship between myopia and blur-driven accommodation in school-aged children. Vision Res (1995) 1.24

Measurement of the electron charge asymmetry in inclusive W production in pp collisions at sqrt[s]=7  TeV. Phys Rev Lett (2012) 1.23

Human herpesvirus 8 (Kaposi's sarcoma-associated herpesvirus) DNA in Kaposi's sarcoma lesions, AIDS Kaposi's sarcoma cell lines, endothelial Kaposi's sarcoma simulators, and the skin of immunosuppressed patients. Am J Pathol (1996) 1.23

Cervical squamous intraepithelial lesions in HIV-infected women: prevalence, incidence and regression. European Study Group on Natural History of HIV Infection in Women. AIDS (2000) 1.22