Derek C Radisky

Author PubWeight™ 81.07‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The organizing principle: microenvironmental influences in the normal and malignant breast. Differentiation 2002 4.64
2 Immune-induced epithelial to mesenchymal transition in vivo generates breast cancer stem cells. Cancer Res 2009 3.30
3 Polarity and proliferation are controlled by distinct signaling pathways downstream of PI3-kinase in breast epithelial tumor cells. J Cell Biol 2004 2.93
4 MYC suppresses cancer metastasis by direct transcriptional silencing of αv and β3 integrin subunits. Nat Cell Biol 2012 2.61
5 Mechanism of Akt1 inhibition of breast cancer cell invasion reveals a protumorigenic role for TSC2. Proc Natl Acad Sci U S A 2006 2.41
6 Mechanisms of disease: epithelial-mesenchymal transition--does cellular plasticity fuel neoplastic progression? Nat Clin Pract Oncol 2008 2.18
7 Matrix metalloproteinase-induced epithelial-mesenchymal transition in breast cancer. J Mammary Gland Biol Neoplasia 2010 2.07
8 Laminin and biomimetic extracellular elasticity enhance functional differentiation in mammary epithelia. EMBO J 2008 1.74
9 Association between mammographic density and age-related lobular involution of the breast. J Clin Oncol 2010 1.70
10 Matrix metalloproteinases stimulate epithelial-mesenchymal transition during tumor development. Clin Exp Metastasis 2008 1.69
11 Matrix metalloproteinase induction of Rac1b, a key effector of lung cancer progression. Sci Transl Med 2012 1.67
12 TGFbeta/TNF(alpha)-mediated epithelial-mesenchymal transition generates breast cancer stem cells with a claudin-low phenotype. Cancer Res 2011 1.65
13 Stromal induction of breast cancer: inflammation and invasion. Rev Endocr Metab Disord 2007 1.51
14 Change in cell shape is required for matrix metalloproteinase-induced epithelial-mesenchymal transition of mammary epithelial cells. J Cell Biochem 2008 1.41
15 Detection of redundant fusion transcripts as biomarkers or disease-specific therapeutic targets in breast cancer. Cancer Res 2012 1.41
16 Clinical characteristics of breast cancers in African-American women with benign breast disease: a comparison to the surveillance, epidemiology, and end results program. Breast J 2014 1.39
17 Microenvironmental influences that drive progression from benign breast disease to invasive breast cancer. J Mammary Gland Biol Neoplasia 2010 1.32
18 Tumor cell-produced matrix metalloproteinase 9 (MMP-9) drives malignant progression and metastasis of basal-like triple negative breast cancer. Oncotarget 2014 1.28
19 Matrix metalloproteinase 3 is a mediator of pulmonary fibrosis. Am J Pathol 2011 1.27
20 Novel breast tissue feature strongly associated with risk of breast cancer. J Clin Oncol 2009 1.23
21 Immune promotion of epithelial-mesenchymal transition and generation of breast cancer stem cells. Cancer Res 2010 1.21
22 Epithelial-mesenchymal transition: general principles and pathological relevance with special emphasis on the role of matrix metalloproteinases. Cold Spring Harb Perspect Biol 2012 1.20
23 Reactivation of suppressed RhoB is a critical step for the inhibition of anaplastic thyroid cancer growth. Cancer Res 2009 1.16
24 Understanding the premalignant potential of atypical hyperplasia through its natural history: a longitudinal cohort study. Cancer Prev Res (Phila) 2014 1.13
25 Host epithelial geometry regulates breast cancer cell invasiveness. Proc Natl Acad Sci U S A 2012 1.09
26 ROS-induced epithelial-mesenchymal transition in mammary epithelial cells is mediated by NF-kB-dependent activation of Snail. Oncotarget 2014 1.07
27 Tissue composition of mammographically dense and non-dense breast tissue. Breast Cancer Res Treat 2011 1.05
28 Matrix metalloproteinase-induced epithelial-mesenchymal transition: tumor progression at Snail's pace. Int J Biochem Cell Biol 2007 1.04
29 Matrix compliance regulates Rac1b localization, NADPH oxidase assembly, and epithelial-mesenchymal transition. Mol Biol Cell 2012 1.04
30 Snail1, Snail2, and E47 promote mammary epithelial branching morphogenesis. EMBO J 2011 1.03
31 Mesotrypsin promotes malignant growth of breast cancer cells through shedding of CD109. Breast Cancer Res Treat 2009 1.00
32 Sclerosing adenosis and risk of breast cancer. Breast Cancer Res Treat 2014 0.99
33 The 19-amino acid insertion in the tumor-associated splice isoform Rac1b confers specific binding to p120 catenin. J Biol Chem 2010 0.99
34 Non-classical export of epimorphin and its adhesion to alphav-integrin in regulation of epithelial morphogenesis. J Cell Sci 2007 0.99
35 Pseudoangiomatous stromal hyperplasia and breast cancer risk. Ann Surg Oncol 2010 0.98
36 NF-kappaB links oestrogen receptor signalling and EMT. Nat Cell Biol 2007 0.97
37 Matrix metalloproteinase-10 (MMP-10) interaction with tissue inhibitors of metalloproteinases TIMP-1 and TIMP-2: binding studies and crystal structure. J Biol Chem 2012 0.97
38 The P(2)' residue is a key determinant of mesotrypsin specificity: engineering a high-affinity inhibitor with anticancer activity. Biochem J 2011 0.95
39 Homology with vesicle fusion mediator syntaxin-1a predicts determinants of epimorphin/syntaxin-2 function in mammary epithelial morphogenesis. J Biol Chem 2009 0.95
40 Extracellular matrix proteins regulate epithelial-mesenchymal transition in mammary epithelial cells. Differentiation 2013 0.94
41 Involvement of hnRNP A1 in the matrix metalloprotease-3-dependent regulation of Rac1 pre-mRNA splicing. J Cell Biochem 2012 0.94
42 Histologic findings in normal breast tissues: comparison to reduction mammaplasty and benign breast disease tissues. Breast Cancer Res Treat 2011 0.94
43 PRSS3/mesotrypsin is a therapeutic target for metastatic prostate cancer. Mol Cancer Res 2012 0.93
44 Growth of lung cancer cells in three-dimensional microenvironments reveals key features of tumor malignancy. Integr Biol (Camb) 2011 0.91
45 miR-200c at the nexus of epithelial-mesenchymal transition, resistance to apoptosis, and the breast cancer stem cell phenotype. Breast Cancer Res 2011 0.89
46 Benign breast disease and the risk of subsequent breast cancer in African American women. Cancer Prev Res (Phila) 2012 0.89
47 Estrogen receptor expression in atypical hyperplasia: lack of association with breast cancer. Cancer Prev Res (Phila) 2011 0.88
48 Malignant mammary cells acquire independence from extracellular context for regulation of estrogen receptor alpha. Clin Cancer Res 2004 0.88
49 Immune cell quantitation in normal breast tissue lobules with and without lobulitis. Breast Cancer Res Treat 2014 0.86
50 Proliferation and polarity in breast cancer: untying the Gordian knot. Cell Cycle 2005 0.86
51 PEGylation extends circulation half-life while preserving in vitro and in vivo activity of tissue inhibitor of metalloproteinases-1 (TIMP-1). PLoS One 2012 0.85
52 An integrated model of the transcriptome of HER2-positive breast cancer. PLoS One 2013 0.84
53 Flat epithelial atypia and risk of breast cancer: A Mayo cohort study. Cancer 2015 0.84
54 Cell plasticity in lung injury and repair: report from an NHLBI workshop, April 19-20, 2010. Proc Am Thorac Soc 2011 0.83
55 Extracellular matrix as a contextual determinant of transforming growth factor-β signaling in epithelial-mesenchymal transition and in cancer. Cell Adh Migr 2014 0.81
56 Extracellular localization of epimorphin/syntaxin-2. Blood 2007 0.80
57 Regulation of mechanical stress by mammary epithelial tissue structure controls breast cancer cell invasion. Oncotarget 2013 0.79
58 Epimorphin is a novel regulator of the progesterone receptor isoform-a. Cancer Res 2013 0.78
59 Separation anxiety: detachment from the extracellular matrix induces metabolic changes that can stimulate tumorigenesis. J Mol Cell Biol 2009 0.77
60 Identifying the stroma as a critical player in radiation-induced mammary tumor development. Cancer Cell 2011 0.77
61 Ki-67 expression in sclerosing adenosis and adjacent normal breast terminal ductal lobular units: a nested case-control study from the Mayo Benign Breast Disease Cohort. Breast Cancer Res Treat 2015 0.77
62 Matrix metalloproteinases as breast cancer drivers and therapeutic targets. Front Biosci (Landmark Ed) 2015 0.76
63 Leading the charge. Nat Cell Biol 2007 0.76
64 The importance of matrix metalloproteinase-3 in respiratory disorders. Expert Rev Respir Med 2014 0.76
65 Gene signature model for breast cancer risk prediction for women with sclerosing adenosis. Breast Cancer Res Treat 2015 0.75
66 Function following form: functional differentiation of mammary epithelial cells requires laminin-induced polarization of PI3-kinase. Cell Cycle 2011 0.75
67 Complex fibroadenoma and breast cancer risk: a Mayo Clinic Benign Breast Disease Cohort Study. Breast Cancer Res Treat 2015 0.75