Published in Biol Pharm Bull on January 01, 2012
Species differences in sinusoidal and canalicular efflux transport of mycophenolic acid 7-O-glucuronide in sandwich-cultured hepatocytes. Pharmacol Res Perspect (2014) 0.75
Fructooligosaccharide raftilose reduces the mycophenolate mofetil-induced complications: Hematological and biochemical alterations. Vet Res Forum (2015) 0.75
Lipid-induced oxidative stress causes steatohepatitis in mice fed an atherogenic diet. Hepatology (2007) 2.74
Circulating FGF-23 is regulated by 1alpha,25-dihydroxyvitamin D3 and phosphorus in vivo. J Biol Chem (2004) 2.72
Essential role of the apoptotic cell engulfment genes draper and ced-6 in programmed axon pruning during Drosophila metamorphosis. Neuron (2006) 2.67
Palmitate induces insulin resistance in H4IIEC3 hepatocytes through reactive oxygen species produced by mitochondria. J Biol Chem (2009) 2.21
Human fibroblast growth factor-23 mutants suppress Na+-dependent phosphate co-transport activity and 1alpha,25-dihydroxyvitamin D3 production. J Biol Chem (2002) 2.12
Growth-related renal type II Na/Pi cotransporter. J Biol Chem (2002) 1.90
CCR5 plays a critical role in obesity-induced adipose tissue inflammation and insulin resistance by regulating both macrophage recruitment and M1/M2 status. Diabetes (2012) 1.56
Genetic polymorphisms of human organic anion transporters OATP-C (SLC21A6) and OATP-B (SLC21A9): allele frequencies in the Japanese population and functional analysis. J Pharmacol Exp Ther (2002) 1.45
Clinicopathological characteristics of follicular lymphoma with peripheral blood involvement. Leuk Lymphoma (2014) 1.39
Expression and functional characterization of the adhesion molecule spermatogenic immunoglobulin superfamily in the mouse testis. Biol Reprod (2002) 1.29
Endoplasmic reticulum stress inhibits STAT3-dependent suppression of hepatic gluconeogenesis via dephosphorylation and deacetylation. Diabetes (2011) 1.10
Type IIc sodium-dependent phosphate transporter regulates calcium metabolism. J Am Soc Nephrol (2008) 1.09
Effect of hydrolysis-resistant FGF23-R179Q on dietary phosphate regulation of the renal type-II Na/Pi transporter. Pflugers Arch (2003) 1.05
Preventive effect of geniposide on metabolic disease status in spontaneously obese type 2 diabetic mice and free fatty acid-treated HepG2 cells. Biol Pharm Bull (2011) 1.01
Reversal of P-glycoprotein-dependent resistance to vinblastine by newly synthesized bisbenzylisoquinoline alkaloids in mouse leukemia P388 cells. Biol Pharm Bull (2005) 1.00
Involvement of carnitine/organic cation transporter OCTN1/SLC22A4 in gastrointestinal absorption of metformin. J Pharm Sci (2013) 0.97
Heterophilic binding of the adhesion molecules poliovirus receptor and immunoglobulin superfamily 4A in the interaction between mouse spermatogenic and Sertoli cells. Biol Reprod (2007) 0.97
Inorganic phosphate homeostasis in sodium-dependent phosphate cotransporter Npt2b⁺/⁻ mice. Am J Physiol Renal Physiol (2011) 0.96
mTORC1 activation triggers the unfolded protein response in podocytes and leads to nephrotic syndrome. Lab Invest (2011) 0.96
Role of amino acid transporter LAT2 in the activation of mTORC1 pathway and the pathogenesis of crescentic glomerulonephritis. Lab Invest (2011) 0.94
Inhibition of epidermal growth factor-induced cell transformation and Akt activation by caffeine. Mol Carcinog (2005) 0.94
Aberrant glycogen synthase kinase 3β is involved in pancreatic cancer cell invasion and resistance to therapy. PLoS One (2013) 0.94
Organic cation/carnitine transporter OCTN2 (Slc22a5) is responsible for carnitine transport across apical membranes of small intestinal epithelial cells in mouse. Mol Pharmacol (2006) 0.93
Predominant contribution of organic anion transporting polypeptide OATP-B (OATP2B1) to apical uptake of estrone-3-sulfate by human intestinal Caco-2 cells. Drug Metab Dispos (2006) 0.93
Characterization of the transdermal transport of flurbiprofen and indomethacin. J Control Release (2005) 0.92
Protecting cisplatin-induced nephrotoxicity with cimetidine does not affect antitumor activity. Biol Pharm Bull (2010) 0.92
Mechanism by which cAMP activates PI3-kinase and increases bile acid secretion in WIF-B9 cells. Am J Physiol Cell Physiol (2002) 0.90
Involvement of multidrug resistance-associated protein 2 in intestinal secretion of grepafloxacin in rats. Antimicrob Agents Chemother (2002) 0.90
Effect of intraperitoneal administration of docetaxel on peritoneal dissemination of gastric cancer. Cancer Lett (2004) 0.90
PDZK1 directly regulates the function of organic cation/carnitine transporter OCTN2. Mol Pharmacol (2004) 0.90
Axonal regeneration of fish optic nerve after injury. Biol Pharm Bull (2004) 0.89
Caveolin-1 in extracellular matrix vesicles secreted from osteoblasts. Bone (2007) 0.89
Wilms' tumor 1 (WT1) peptide immunotherapy for gynecological malignancy. Anticancer Res (2009) 0.88
Contribution of organic anion transporting polypeptide OATP-C to hepatic elimination of the opioid pentapeptide analogue [D-Ala2, D-Leu5]-enkephalin. J Pharm Pharmacol (2003) 0.88
Targeted drug delivery to bone: pharmacokinetic and pharmacological properties of acidic oligopeptide-tagged drugs. Curr Drug Discov Technol (2008) 0.87
Platelet-derived growth factor-BB (PDGF-BB) induces differentiation of bone marrow endothelial progenitor cell-derived cell line TR-BME2 into mural cells, and changes the phenotype. J Cell Physiol (2005) 0.87
Activation of a non-cAMP/PKA signaling pathway downstream of the PTH/PTHrP receptor is essential for a sustained hypophosphatemic response to PTH infusion in male mice. Endocrinology (2013) 0.87
Pharmacokinetics of [6]-shogaol, a pungent ingredient of Zingiber officinale Roscoe (Part I). J Nat Med (2010) 0.86
Antinociceptive effect of methyleugenol on formalin-induced hyperalgesia in mice. Eur J Pharmacol (2006) 0.86
Long-term levothyroxine treatment decreases the oral bioavailability of cyclosporin A by inducing P-glycoprotein in small intestine. Drug Metab Pharmacokinet (2005) 0.86
Functional characterization of human organic cation transporter OCTN1 single nucleotide polymorphisms in the Japanese population. J Pharm Sci (2004) 0.85
Role of membrane microdomains in PTH-mediated down-regulation of NaPi-IIa in opossum kidney cells. Kidney Int (2005) 0.85
Involvement of carnitine/organic cation transporter OCTN2 (SLC22A5) in distribution of its substrate carnitine to the heart. Drug Metab Pharmacokinet (2008) 0.85
PepT1 mRNA expression is induced by starvation and its level correlates with absorptive transport of cefadroxil longitudinally in the rat intestine. Pharm Res (2002) 0.85
Lowered blood concentration of tacrolimus and its recovery with changes in expression of CYP3A and P-glycoprotein after high-dose steroid therapy. Transplantation (2002) 0.85
Acetyl-L-carnitine permeability across the blood-brain barrier and involvement of carnitine transporter OCTN2. Biopharm Drug Dispos (2003) 0.84
Characterization of the uptake mechanism for a novel loop diuretic, M17055, in Caco-2 cells: involvement of organic anion transporting polypeptide (OATP)-B. Pharm Res (2006) 0.84
Involvement of OCTN1 (SLC22A4) in pH-dependent transport of organic cations. Mol Pharm (2004) 0.84
Obesity-induced increase of CYP2E1 activity and its effect on disposition kinetics of chlorzoxazone in Zucker rats. Biochem Pharmacol (2006) 0.84
Dose dependent development of diabetes mellitus and non-alcoholic steatohepatitis in monosodium glutamate-induced obese mice. Life Sci (2009) 0.84
Effects of heavy metals on riverine benthic macroinvertebrate assemblages with reference to potential food availability for drift-feeding fishes. Environ Toxicol Chem (2009) 0.84
Altered expression of basement membrane-related molecules in rat brain pericyte, endothelial, and astrocyte cell lines after transforming growth factor-beta1 treatment. Drug Metab Pharmacokinet (2007) 0.84
Pharmacist-based Donepezil Outpatient Consultation Service to improve medication persistence. Patient Prefer Adherence (2012) 0.83
Marked difference in pathophysiology between tissue factor- and lipopolysaccharide-induced disseminated intravascular coagulation models in rats. Crit Care Med (2002) 0.83
Dietary phosphate restriction ameliorates endothelial dysfunction in adenine-induced kidney disease rats. J Clin Biochem Nutr (2012) 0.83
Mycophenolate mofetil is effective and well tolerated in the treatment of refractory acute and chronic graft-versus-host disease. Int J Hematol (2006) 0.83
Evaluation of blood-brain barrier transporters by co-culture of brain capillary endothelial cells with astrocytes. Drug Metab Pharmacokinet (2002) 0.83
Transport of carnitine and acetylcarnitine by carnitine/organic cation transporter (OCTN) 2 and OCTN3 into epididymal spermatozoa. Reproduction (2007) 0.82
Salacia reticulata inhibits differentiation of 3T3-L1 adipocytes. J Ethnopharmacol (2011) 0.82
Screening of the interaction between xenobiotic transporters and PDZ proteins. Pharm Res (2004) 0.82
GPI-anchor synthesis is indispensable for the germline development of the nematode Caenorhabditis elegans. Mol Biol Cell (2012) 0.82
Experimental demonstration of the unstirred water layer effect on drug transport in Caco-2 cells. J Pharm Sci (2003) 0.82
Selenoprotein P as a diabetes-associated hepatokine that impairs angiogenesis by inducing VEGF resistance in vascular endothelial cells. Diabetologia (2014) 0.82
Studies on functional sites of organic cation/carnitine transporter OCTN2 (SLC22A5) using a Ser467Cys mutant protein. J Pharmacol Exp Ther (2002) 0.82
Vitamin A deficiency induces a decrease in EEG delta power during sleep in mice. Brain Res (2007) 0.82
Mechanism of decrease of oral bioavailability of cyclosporin A during immunotherapy upon coadministration of amphotericin B. Biopharm Drug Dispos (2008) 0.82
Anxiolytic effect of music depends on ovarian steroid in female mice. Behav Brain Res (2007) 0.82
Effect of low-dose Paclitaxel and docetaxel on endothelial progenitor cells. Oncology (2009) 0.82
Thyroid hormones regulate phosphate homoeostasis through transcriptional control of the renal type IIa sodium-dependent phosphate co-transporter (Npt2a) gene. Biochem J (2010) 0.82
[Development of evaluation methods for student performance in National Universities: formative assessment and portfolio]. Yakugaku Zasshi (2012) 0.82
Salacia reticulata has therapeutic effects on obesity. J Nat Med (2014) 0.81
Involvement of multidrug resistance-associated protein 2 (Abcc2) in molecular weight-dependent biliary excretion of beta-lactam antibiotics. Drug Metab Dispos (2008) 0.81
Involvement of ABC transporters in chemosensitivity of human renal cell carcinoma, and regulation of MRP2 expression by conjugated bilirubin. Anticancer Res (2005) 0.81
Functional regions of organic cation/carnitine transporter OCTN2 (SLC22A5): roles in carnitine recognition. Drug Metab Pharmacokinet (2004) 0.80
The genetic polymorphism of drug transporters: functional analysis approaches. Pharmacogenomics (2004) 0.80
Ligand-dependent EphB1 signaling suppresses glioma invasion and correlates with patient survival. Neuro Oncol (2013) 0.80
[Improvement of epirubicin-induced phlebitis to switch from liquid preparation to lyophilized formulation]. Gan To Kagaku Ryoho (2009) 0.80
Requirement of retinoic acid receptor β for genipin derivative-induced optic nerve regeneration in adult rat retina. PLoS One (2013) 0.80
Differential expression of ezrin and CLP36 in the two layers of syncytiotrophoblast in rats. Biol Pharm Bull (2010) 0.80
Toxicity of diazinon and its metabolites increases in diabetic rats. Toxicol Lett (2007) 0.79
Selective drug delivery to bone using acidic oligopeptides. J Bone Miner Metab (2008) 0.79
Preventive effect of pine bark extract (flavangenol) on metabolic disease in Western diet-loaded tsumura suzuki obese diabetes mice. Evid Based Complement Alternat Med (2011) 0.79
Pathophysiology of disseminated intravascular coagulation (DIC) progresses at a different rate in tissue factor-induced and lipopolysaccharide-induced DIC models in rats. Blood Coagul Fibrinolysis (2003) 0.79
Prediction of theophylline clearance in CCl4-treated rats using in vivo CYP1A2 and CYP3A2 contents assessed with the PKCYP test. Drug Metab Pharmacokinet (2005) 0.79
Inhibitory effect of supramolecular polyrotaxane-dipeptide conjugates on digested peptide uptake via intestinal human peptide transporter. Bioconjug Chem (2002) 0.78
Interaction of a farnesylated protein with renal type IIa Na/Pi co-transporter in response to parathyroid hormone and dietary phosphate. Biochem J (2004) 0.78
Multidrug resistance-associated protein 1 functions as an efflux pump of xenobiotics in the skin. Pharm Res (2005) 0.78
Expression, localization, and binding activity of the ezrin/radixin/moesin proteins in the mouse testis. J Histochem Cytochem (2008) 0.78
Na+/H+ exchanger 3 affects transport property of H+/oligopeptide transporter 1. Drug Metab Pharmacokinet (2005) 0.78
Mechanism of nucleoside uptake in rat placenta and induction of placental CNT2 in experimental diabetes. Drug Metab Pharmacokinet (2012) 0.78