H Richard Alexander

Author PubWeight™ 95.86‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Randomized multicenter trial of hyperthermic isolated limb perfusion with melphalan alone compared with melphalan plus tumor necrosis factor: American College of Surgeons Oncology Group Trial Z0020. J Clin Oncol 2006 2.60
2 Prospective molecular profiling of melanoma metastases suggests classifiers of immune responsiveness. Cancer Res 2002 2.21
3 Analysis of factors associated with outcome in patients with malignant peritoneal mesothelioma undergoing surgical debulking and intraperitoneal chemotherapy. J Clin Oncol 2003 2.05
4 Interleukin-1 and cancer progression: the emerging role of interleukin-1 receptor antagonist as a novel therapeutic agent in cancer treatment. J Transl Med 2006 1.98
5 Phase I and pharmacokinetic studies of CYT-6091, a novel PEGylated colloidal gold-rhTNF nanomedicine. Clin Cancer Res 2010 1.87
6 Consequences of adrenal venous sampling in primary hyperaldosteronism and predictors of unilateral adrenal disease. J Am Coll Surg 2010 1.70
7 The role of interleukin 1 in growth and metastasis of human cancer xenografts. Clin Cancer Res 2006 1.68
8 Clinical, genetic and radiographic analysis of 108 patients with von Hippel-Lindau disease (VHL) manifested by pancreatic neuroendocrine neoplasms (PNETs). Surgery 2007 1.67
9 Prospective analysis of circulating endostatin levels in patients with renal cell carcinoma. Cancer 2002 1.65
10 Localization of insulinomas to regions of the pancreas by intraarterial calcium stimulation: the NIH experience. J Clin Endocrinol Metab 2009 1.62
11 Regional treatment options for patients with ocular melanoma metastatic to the liver. Ann Surg Oncol 2004 1.55
12 Reoperation for parathyroid adenoma: a contemporary experience. Surgery 2009 1.50
13 Direct evidence for rapid and selective induction of tumor neovascular permeability by tumor necrosis factor and a novel derivative, colloidal gold bound tumor necrosis factor. Int J Cancer 2007 1.43
14 Comparison of noninvasive fluorescent and bioluminescent small animal optical imaging. Biotechniques 2003 1.36
15 Radiofrequency ablation of adrenal tumors and adrenocortical carcinoma metastases. Cancer 2003 1.36
16 Integration of metabolomics and transcriptomics revealed a fatty acid network exerting growth inhibitory effects in human pancreatic cancer. Clin Cancer Res 2013 1.31
17 DPEP1 inhibits tumor cell invasiveness, enhances chemosensitivity and predicts clinical outcome in pancreatic ductal adenocarcinoma. PLoS One 2012 1.30
18 Combining agents that target the tumor microenvironment improves the efficacy of anticancer therapy. Clin Cancer Res 2008 1.29
19 Successful outcome after surgical management in two cases of the "painful variant" of Hashimoto's thyroiditis. Endocr Pract 2002 1.25
20 Parathyroid gland-specific deletion of the mouse Men1 gene results in parathyroid neoplasia and hypercalcemic hyperparathyroidism. Cancer Res 2003 1.22
21 Using gene expression profiling to differentiate benign versus malignant thyroid tumors. Cancer Res 2004 1.21
22 Oncolytic vaccinia virus expressing the human somatostatin receptor SSTR2: molecular imaging after systemic delivery using 111In-pentetreotide. Mol Ther 2004 1.21
23 Does the use of routine duodenotomy (DUODX) affect rate of cure, development of liver metastases, or survival in patients with Zollinger-Ellison syndrome? Ann Surg 2004 1.20
24 Induction of permeability across endothelial cell monolayers by tumor necrosis factor (TNF) occurs via a tissue factor-dependent mechanism: relationship between the procoagulant and permeability effects of TNF. Blood 2002 1.20
25 Possible primary lymph node gastrinoma: occurrence, natural history, and predictive factors: a prospective study. Ann Surg 2003 1.20
26 A pilot feasibility study of TNFerade™ biologic with capecitabine and radiation therapy followed by surgical resection for the treatment of rectal cancer. Oncology 2011 1.18
27 Malignant insulinoma: spectrum of unusual clinical features. Cancer 2005 1.07
28 Blind distal pancreatectomy for occult insulinoma, an inadvisable procedure. J Am Coll Surg 2002 1.07
29 Surgical treatment of malignant peritoneal mesothelioma: past, present, and future. Ann Surg Oncol 2010 1.07
30 Phase I study of hepatic arterial melphalan infusion and hepatic venous hemofiltration using percutaneously placed catheters in patients with unresectable hepatic malignancies. J Clin Oncol 2005 1.06
31 Current concepts in the evaluation and treatment of patients with diffuse malignant peritoneal mesothelioma. J Natl Compr Canc Netw 2012 1.06
32 A prospective evaluation of laparoscopic exploration with intraoperative ultrasound as a technique for localizing sporadic insulinomas. Surgery 2005 1.06
33 Activation of the phosphoinositide-3-kinase and mammalian target of rapamycin signaling pathways are associated with shortened survival in patients with malignant peritoneal mesothelioma. Cancer 2010 1.02
34 Role of metastasectomy in the management of thyroid carcinoma: the NIH experience. J Surg Oncol 2003 1.01
35 Pseudo-Meigs' syndrome secondary to isolated colorectal metastasis to ovary: a case report and review of the literature. Gynecol Oncol 2004 1.00
36 Microarray gene expression analysis of murine tumor heterogeneity defined by dynamic contrast-enhanced MRI. Mol Imaging 2002 1.00
37 Hyperparathyroidism in hereditary syndromes: special expressions and special managements. J Bone Miner Res 2002 1.00
38 Retroviral gene transfer of interferon-inducible protein 10 inhibits growth of human melanoma xenografts. Int J Cancer 2002 0.99
39 Macrophage migration inhibitory factor induces epithelial to mesenchymal transition, enhances tumor aggressiveness and predicts clinical outcome in resected pancreatic ductal adenocarcinoma. Int J Cancer 2013 0.99
40 Neuroendocrine tumors of the pancreas in von Hippel-Lindau disease: spectrum of appearances at CT and MR imaging with histopathologic comparison. Radiology 2002 0.98
41 Results of initial operation for hyperparathyroidism in patients with multiple endocrine neoplasia type 1. Surgery 2003 0.97
42 A novel nomogram for peritoneal mesothelioma predicts survival. Ann Surg Oncol 2012 0.96
43 Persistent primary hyperparathyroidism caused by adenomas identified in pharyngeal or adjacent structures. World J Surg 2003 0.96
44 Targeting vaccinia to solid tumors with local hyperthermia. Hum Gene Ther 2005 0.95
45 Intravenous and isolated limb perfusion delivery of wild type and a tumor-selective replicating mutant vaccinia virus in nonhuman primates. Hum Gene Ther 2006 0.95
46 Effect of interleukin 1 receptor antagonist gene transduction on human melanoma xenografts in nude mice. Cancer Res 2003 0.95
47 Interferon gamma-inducible protein 10 selectively inhibits proliferation and induces apoptosis in endothelial cells. Ann Surg Oncol 2006 0.94
48 Transarterial perfusion of liver metastases. Semin Oncol 2002 0.93
49 Operative management of Cushing syndrome secondary to micronodular adrenal hyperplasia. Surgery 2008 0.92
50 Site-specific gene expression profiles and novel molecular prognostic factors in patients with lower gastrointestinal adenocarcinoma diffusely metastatic to liver or peritoneum. Ann Surg Oncol 2007 0.92
51 Interleukin-1beta induced vascular permeability is dependent on induction of endothelial tissue factor (TF) activity. J Transl Med 2005 0.91
52 Endothelial monocyte activating polypeptide-II induced gene expression changes in endothelial cells. Cytokine 2005 0.91
53 Cytoreductive surgery and continuous hyperthermic peritoneal perfusion in patients with mesothelioma and peritoneal carcinomatosis: hemodynamic, metabolic, and anesthetic considerations. Ann Surg Oncol 2008 0.90
54 Management and outcome of patients with sporadic gastrinoma arising in the duodenum. Ann Surg 2003 0.90
55 18F-FDG PET/CT in a recurrent diffuse malignant peritoneal mesothelioma. Clin Nucl Med 2012 0.90
56 Utility of rapid intraoperative parathyroid hormone assay to predict severe postoperative hypocalcemia after reoperation for hyperparathyroidism. Surgery 2002 0.89
57 A six-gene model for differentiating benign from malignant thyroid tumors on the basis of gene expression. Surgery 2005 0.89
58 Multipotent cancer stem cells derived from human malignant peritoneal mesothelioma promote tumorigenesis. PLoS One 2012 0.88
59 The past decade of experience with isolated hepatic perfusion. Oncologist 2004 0.88
60 Modulation of tumor-host interactions, angiogenesis, and tumor growth by tissue inhibitor of metalloproteinase 2 via a novel mechanism. Cancer Res 2004 0.87
61 Gland size is associated with changes in gene expression profiles in sporadic parathyroid adenomas. Ann Surg Oncol 2005 0.87
62 The utility of routine transcervical thymectomy for multiple endocrine neoplasia 1-related hyperparathyroidism. Surgery 2008 0.87
63 Percutaneous hepatic perfusion in patients with metastatic liver cancer: anesthetic, hemodynamic, and metabolic considerations. Ann Surg Oncol 2008 0.86
64 A novel technique for quantifying changes in vascular density, endothelial cell proliferation and protein expression in response to modulators of angiogenesis using the chick chorioallantoic membrane (CAM) assay. J Transl Med 2004 0.85
65 Diffuse mesothelioma of the peritoneum: correlation between histological and clinical parameters and survival in 73 patients. Pathology 2014 0.85
66 FOXL1, a novel candidate tumor suppressor, inhibits tumor aggressiveness and predicts outcome in human pancreatic cancer. Cancer Res 2013 0.85
67 Augmentation of endothelial cell monolayer permeability by hyperthermia but not tumor necrosis factor: evidence for disruption of vascular integrity via VE-cadherin down-regulation. Int J Oncol 2003 0.84
68 Diffuse mesothelioma of the peritoneum: a pathological study of 64 tumours treated with cytoreductive therapy. Pathology 2013 0.83
69 Assessment of clinical benefit and quality of life in patients undergoing cytoreduction and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) for management of peritoneal metastases. J Gastrointest Oncol 2013 0.83
70 Isolated hepatic perfusion for the treatment of patients with advanced liver metastases from pancreatic and gastrointestinal neuroendocrine neoplasms. Surgery 2004 0.82
71 von Hippel-Lindau disease-associated solid microcystic serous adenomas masquerading as pancreatic neuroendocrine neoplasms. Surgery 2012 0.82
72 Isolated hepatic perfusion with high-dose melphalan results in immediate alterations in tumor gene expression in patients with metastatic ocular melanoma. Ann Surg Oncol 2010 0.82
73 Limited survival in patients with carcinomatosis from foregut malignancies after cytoreduction and continuous hyperthermic peritoneal perfusion. J Gastrointest Surg 2005 0.81
74 Development of isolated hepatic perfusion for patients who have unresectable hepatic malignancies. Surg Oncol Clin N Am 2008 0.81
75 Treatment of patients with unresectable primary hepatic malignancies using hyperthermic isolated hepatic perfusion. J Gastrointest Surg 2004 0.81
76 Intraperitoneal gemcitabine pharmacokinetics: a pilot and pharmacokinetic study in patients with advanced adenocarcinoma of the pancreas. Cancer Chemother Pharmacol 2007 0.81
77 TNF-based isolated hepatic perfusion. Front Biosci (Landmark Ed) 2009 0.79
78 Porcelain gallbladder and cancer: ethnicity explains a discrepant literature? Am J Med 2007 0.79
79 Isolation perfusion of the liver. Cancer J 2002 0.79
80 Current role of hepatic artery infusion and isolated liver perfusion for the treatment of colorectal cancer liver metastases. Cancer J 2004 0.79
81 The impact of major surgery on blood coagulation factors and thrombin generation. Am J Hematol 2007 0.78
82 Value of surgery in patients with negative imaging and sporadic Zollinger-Ellison syndrome. Ann Surg 2012 0.78
83 Hyperthermia and its modern use in cancer treatment. Cancer 2003 0.77
84 Alterations in tumor necrosis factor-induced endothelial cell procoagulant activity by hyperthermia. Int J Cancer 2004 0.77
85 Development of a melanoma-specific adenovirus. Mol Ther 2002 0.76
86 Palliative interventions in patients with peritoneal metastases and malignant bowel obstruction. J Clin Oncol 2012 0.76
87 Long-term influence of chemotherapy on steatosis-associated advanced hepatic fibrosis. Med Oncol 2014 0.76
88 Gastrinoma: sporadic and familial disease. Surg Oncol Clin N Am 2006 0.75
89 Hyperthermic isolated hepatic perfusion for the treatment of unresectable cancers confined to the liver. J Surg Oncol 2002 0.75
90 Surgery for peritoneal mesothelioma. Curr Treat Options Oncol 2011 0.75
91 A motion for cautious optimism in the treatment of patients with ocular melanoma: the ayes have it. Ann Surg Oncol 2005 0.75
92 Peak stimulated insulin secretion is associated with specific changes in gene expression profiles in sporadic insulinomas. Surgery 2003 0.75
93 Regional therapies for cancer. Ann Surg Oncol 2013 0.75
94 Rapid measurement of insulin using the Abbott IMx: application to the management of insulinoma. Ann Clin Biochem 2002 0.75
95 Isolated hepatic perfusion: treating unresectable liver metastases. Adv Exp Med Biol 2006 0.75