Published in Ophthalmology on July 26, 2012
Nutraceutical Support With Omega-3 | NCT03712670
A Study to Evaluate the Safety and Efficacy of RQC for AMD | NCT05062486
Secondary analyses of the effects of lutein/zeaxanthin on age-related macular degeneration progression: AREDS2 report No. 3. JAMA Ophthalmol (2014) 4.34
Effect of Omega-3 Fatty Acids, Lutein/Zeaxanthin, or Other Nutrient Supplementation on Cognitive Function: The AREDS2 Randomized Clinical Trial. JAMA (2015) 3.88
Identification of a rare coding variant in complement 3 associated with age-related macular degeneration. Nat Genet (2013) 1.39
Quantitative classification of eyes with and without intermediate age-related macular degeneration using optical coherence tomography. Ophthalmology (2013) 1.35
Randomized trial of a home monitoring system for early detection of choroidal neovascularization home monitoring of the Eye (HOME) study. Ophthalmology (2013) 1.26
Microglial aging in the healthy CNS: phenotypes, drivers, and rejuvenation. Front Cell Neurosci (2013) 1.20
Genetic evidence for role of carotenoids in age-related macular degeneration in the Carotenoids in Age-Related Eye Disease Study (CAREDS). Invest Ophthalmol Vis Sci (2014) 0.95
Methods and reproducibility of grading optimized digital color fundus photographs in the Age-Related Eye Disease Study 2 (AREDS2 Report Number 2). Invest Ophthalmol Vis Sci (2013) 0.94
Blue-light reflectance imaging of macular pigment in infants and children. Invest Ophthalmol Vis Sci (2013) 0.92
Long term effects of lutein, zeaxanthin and omega-3-LCPUFAs supplementation on optical density of macular pigment in AMD patients: the LUTEGA study. Graefes Arch Clin Exp Ophthalmol (2013) 0.91
Perspective: A Critical Look at the Ancillary Age-Related Eye Disease Study 2: Nutrition and Cognitive Function Results in Older Individuals with Age-Related Macular Degeneration. Adv Nutr (2016) 0.89
The role of lutein in eye-related disease. Nutrients (2013) 0.89
Age-related Eye Disease Study 2: perspectives, recommendations, and unanswered questions. Curr Opin Ophthalmol (2014) 0.87
Antioxidant drug therapy approaches for neuroprotection in chronic diseases of the retina. Int J Mol Sci (2014) 0.85
Aspirin use and risk of age-related macular degeneration: a meta-analysis. PLoS One (2013) 0.85
Botanical compounds: effects on major eye diseases. Evid Based Complement Alternat Med (2013) 0.84
Retracted Potential role of lampalizumab for treatment of geographic atrophy. Clin Ophthalmol (2015) 0.81
Comparison of Mouse and Human Retinal Pigment Epithelium Gene Expression Profiles: Potential Implications for Age-Related Macular Degeneration. PLoS One (2015) 0.80
Present and possible therapies for age-related macular degeneration. ISRN Ophthalmol (2014) 0.79
Evaluation of Geographic Atrophy from Color Photographs and Fundus Autofluorescence Images: Age-Related Eye Disease Study 2 Report Number 11. Ophthalmology (2016) 0.78
Visual acuity after cataract surgery in patients with age-related macular degeneration: age-related eye disease study 2 report number 5. Ophthalmology (2014) 0.78
Effect of supplemental lutein and zeaxanthin on serum, macular pigmentation, and visual performance in patients with early age-related macular degeneration. Biomed Res Int (2015) 0.78
European survey on the opinion and use of micronutrition in age-related macular degeneration: 10 years on from the Age-Related Eye Disease Study. Clin Ophthalmol (2014) 0.78
Macular xanthophylls, lipoprotein-related genes, and age-related macular degeneration. Am J Clin Nutr (2014) 0.76
Advances in technology helps in early detection of vision disorders. Indian J Ophthalmol (2013) 0.75
The Association of Statin Use with Cataract Progression and Cataract Surgery: The AREDS2 Report Number 8. Ophthalmology (2015) 0.75
Personalized Medicine in Ophthalmology: From Pharmacogenetic Biomarkers to Therapeutic and Dosage Optimization. J Pers Med (2013) 0.75
Bivariate Analysis of Age-Related Macular Degeneration Progression Using Genetic Risk Scores. Genetics (2017) 0.75
The Age-Related Eye Disease 2 Study: Micronutrients in the Treatment of Macular Degeneration. Adv Nutr (2017) 0.75
Optical Coherence Tomography Reflective Drusen Substructures Predict Progression to Geographic Atrophy in Age-related Macular Degeneration. Ophthalmology (2016) 0.75
The Association of Statin Use with Age-Related Macular Degeneration Progression: The Age-Related Eye Disease Study 2 Report Number 9. Ophthalmology (2015) 0.75
ω-3 and ω-6 long-chain PUFAs and their enzymatic metabolites in neovascular eye diseases. Am J Clin Nutr (2017) 0.75
Nutrition, Genes, and Age-Related Macular Degeneration: What Have We Learned from the Trials? Ophthalmologica (2017) 0.75
Risk of Deficiency in Multiple Concurrent Micronutrients in Children and Adults in the United States. Nutrients (2017) 0.75
[Supplements in age-related macular degeneration: recommendations by the German Ophthalmological Society, the German Retina Society and the German Professional Association of Ophthalmologists--October 2014]. Ophthalmologe (2015) 0.75
A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8. Arch Ophthalmol (2001) 21.37
Prevalence of age-related macular degeneration in the United States. Arch Ophthalmol (2004) 18.86
Causes and prevalence of visual impairment among adults in the United States. Arch Ophthalmol (2004) 13.78
Dietary reference intakes: vitamin A, vitamin K, arsenic, boron, chromium, copper, iodine, iron, manganese, molybdenum, nickel, silicon, vanadium, and zinc. J Am Diet Assoc (2001) 11.66
Risk factors for lung cancer and for intervention effects in CARET, the Beta-Carotene and Retinol Efficacy Trial. J Natl Cancer Inst (1996) 5.63
Dietary carotenoids, vitamins A, C, and E, and advanced age-related macular degeneration. Eye Disease Case-Control Study Group. JAMA (1994) 5.43
Chemistry and metabolism of lipids in the vertebrate retina. Prog Lipid Res (1983) 4.07
Prevalence of cataract and pseudophakia/aphakia among adults in the United States. Arch Ophthalmol (2004) 3.78
A simplified severity scale for age-related macular degeneration: AREDS Report No. 18. Arch Ophthalmol (2005) 3.74
Oral zinc in macular degeneration. Arch Ophthalmol (1988) 3.58
A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E and beta carotene for age-related cataract and vision loss: AREDS report no. 9. Arch Ophthalmol (2001) 3.49
The role of omega-3 long-chain polyunsaturated fatty acids in health and disease of the retina. Prog Retin Eye Res (2005) 3.03
The relationship of dietary carotenoid and vitamin A, E, and C intake with age-related macular degeneration in a case-control study: AREDS Report No. 22. Arch Ophthalmol (2007) 3.02
Biologic mechanisms of the protective role of lutein and zeaxanthin in the eye. Annu Rev Nutr (2003) 2.63
Progression of age-related macular degeneration: association with dietary fat, transunsaturated fat, nuts, and fish intake. Arch Ophthalmol (2003) 2.50
Dietary fat and risk for advanced age-related macular degeneration. Arch Ophthalmol (2001) 2.27
Effects of alpha-tocopherol and beta-carotene supplements on cancer incidence in the Alpha-Tocopherol Beta-Carotene Cancer Prevention Study. Am J Clin Nutr (1995) 2.25
Antioxidant status and neovascular age-related macular degeneration. Eye Disease Case-Control Study Group. Arch Ophthalmol (1993) 2.24
Cigarette smoking, fish consumption, omega-3 fatty acid intake, and associations with age-related macular degeneration: the US Twin Study of Age-Related Macular Degeneration. Arch Ophthalmol (2006) 2.21
Lutein, zeaxanthin, and the macular pigment. Arch Biochem Biophys (2001) 2.18
The relationship of dietary omega-3 long-chain polyunsaturated fatty acid intake with incident age-related macular degeneration: AREDS report no. 23. Arch Ophthalmol (2008) 1.93
Dietary antioxidants and the long-term incidence of age-related macular degeneration: the Blue Mountains Eye Study. Ophthalmology (2007) 1.90
Antioxidant intake and risk of incident age-related nuclear cataracts in the Beaver Dam Eye Study. Am J Epidemiol (1999) 1.73
Lutein and zeaxanthin in the diet and serum and their relation to age-related maculopathy in the third national health and nutrition examination survey. Am J Epidemiol (2001) 1.59
Associations between intermediate age-related macular degeneration and lutein and zeaxanthin in the Carotenoids in Age-related Eye Disease Study (CAREDS): ancillary study of the Women's Health Initiative. Arch Ophthalmol (2006) 1.55
{omega}-3 Long-chain polyunsaturated fatty acid intake and 12-y incidence of neovascular age-related macular degeneration and central geographic atrophy: AREDS report 30, a prospective cohort study from the Age-Related Eye Disease Study. Am J Clin Nutr (2009) 1.44
Plasma lutein and zeaxanthin and other carotenoids as modifiable risk factors for age-related maculopathy and cataract: the POLA Study. Invest Ophthalmol Vis Sci (2006) 1.39
Oily fish consumption, dietary docosahexaenoic acid and eicosapentaenoic acid intakes, and associations with neovascular age-related macular degeneration. Am J Clin Nutr (2008) 1.29
Dietary fatty acids and the 5-year incidence of age-related maculopathy. Arch Ophthalmol (2006) 1.22
Measurement of carotenoids, retinoids, and tocopherols in human lenses. Invest Ophthalmol Vis Sci (1995) 1.22
Associations between age-related nuclear cataract and lutein and zeaxanthin in the diet and serum in the Carotenoids in the Age-Related Eye Disease Study, an Ancillary Study of the Women's Health Initiative. Arch Ophthalmol (2008) 1.19
The impact of fish and shellfish consumption on age-related macular degeneration. Ophthalmology (2010) 1.11
Neovascular age-related macular degeneration and its relationship to antioxidant intake. Acta Ophthalmol Scand (2002) 1.08
Omega-3 long-chain polyunsaturated fatty acid intake inversely associated with 12-year progression to advanced age-related macular degeneration. Arch Ophthalmol (2009) 1.05
Blood levels of vitamin C, carotenoids and retinol are inversely associated with cataract in a North Indian population. Invest Ophthalmol Vis Sci (2008) 1.03
Lutein and zeaxanthin and the risk of cataract: the Melbourne visual impairment project. Invest Ophthalmol Vis Sci (2006) 0.98
Xanthophylls and alpha-tocopherol decrease UVB-induced lipid peroxidation and stress signaling in human lens epithelial cells. J Nutr (2004) 0.98
Lutein prevents cataract development and progression in diabetic rats. Graefes Arch Clin Exp Ophthalmol (2008) 0.96
Underwood Memorial Lecture: human zinc homeostasis: good but not perfect. J Nutr (2003) 0.95
Cataract surgery and the primary care practitioner. Geriatrics (2009) 0.81
Lutein and age-related ocular disorders in the older adult: a review. J Nutr Elder (2007) 0.81
Dietary modulation of lens zeaxanthin in quail. Exp Eye Res (2005) 0.78
Complement factor H polymorphism in age-related macular degeneration. Science (2005) 31.10
Ranibizumab and bevacizumab for treatment of neovascular age-related macular degeneration: two-year results. Ophthalmology (2012) 11.91
Effects of medical therapies on retinopathy progression in type 2 diabetes. N Engl J Med (2010) 10.75
Randomized trial evaluating ranibizumab plus prompt or deferred laser or triamcinolone plus prompt laser for diabetic macular edema. Ophthalmology (2010) 10.28
A computerized method of visual acuity testing: adaptation of the early treatment of diabetic retinopathy study testing protocol. Am J Ophthalmol (2003) 9.99
Proposed international clinical diabetic retinopathy and diabetic macular edema disease severity scales. Ophthalmology (2003) 8.98
Aflibercept, bevacizumab, or ranibizumab for diabetic macular edema. N Engl J Med (2015) 7.08
von Hippel-Lindau disease. Lancet (2003) 6.20
The Age-Related Eye Disease Study severity scale for age-related macular degeneration: AREDS Report No. 17. Arch Ophthalmol (2005) 4.46
Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration. Proc Natl Acad Sci U S A (2010) 4.30
Expanded 2-year follow-up of ranibizumab plus prompt or deferred laser or triamcinolone plus prompt laser for diabetic macular edema. Ophthalmology (2011) 4.15
Seven new loci associated with age-related macular degeneration. Nat Genet (2013) 3.81
A simplified severity scale for age-related macular degeneration: AREDS Report No. 18. Arch Ophthalmol (2005) 3.74
Cardiovascular risk of celecoxib in 6 randomized placebo-controlled trials: the cross trial safety analysis. Circulation (2008) 3.63
Age-related macular degeneration. Lancet (2008) 3.34
Risk factors for the incidence of Advanced Age-Related Macular Degeneration in the Age-Related Eye Disease Study (AREDS) AREDS report no. 19. Ophthalmology (2005) 3.28
Increased prevalence of myopia in the United States between 1971-1972 and 1999-2004. Arch Ophthalmol (2009) 3.21
Potential public health impact of Age-Related Eye Disease Study results: AREDS report no. 11. Arch Ophthalmol (2003) 3.17
Prevalence of refractive error in the United States, 1999-2004. Arch Ophthalmol (2008) 3.06
The role of omega-3 long-chain polyunsaturated fatty acids in health and disease of the retina. Prog Retin Eye Res (2005) 3.03
The relationship of dietary carotenoid and vitamin A, E, and C intake with age-related macular degeneration in a case-control study: AREDS Report No. 22. Arch Ophthalmol (2007) 3.02
Panretinal photocoagulation for proliferative diabetic retinopathy. N Engl J Med (2011) 2.98
Diabetic retinopathy. Diabetes Care (2004) 2.97
Visual acuity as an outcome measure in clinical trials of retinal diseases. Ophthalmology (2007) 2.69
Intravitreal ranibizumab for diabetic macular edema with prompt versus deferred laser treatment: three-year randomized trial results. Ophthalmology (2012) 2.68
Unraveling a multifactorial late-onset disease: from genetic susceptibility to disease mechanisms for age-related macular degeneration. Annu Rev Genomics Hum Genet (2009) 2.40
Fundus autofluorescence imaging of the white dot syndromes. Arch Ophthalmol (2010) 2.26
The relationship of dietary lipid intake and age-related macular degeneration in a case-control study: AREDS Report No. 20. Arch Ophthalmol (2007) 2.12
The involvement of sequence variation and expression of CX3CR1 in the pathogenesis of age-related macular degeneration. FASEB J (2004) 2.04
The relationship of dietary omega-3 long-chain polyunsaturated fatty acid intake with incident age-related macular degeneration: AREDS report no. 23. Arch Ophthalmol (2008) 1.93
Serum inflammatory markers in diabetic retinopathy. Invest Ophthalmol Vis Sci (2005) 1.92
Folic acid, pyridoxine, and cyanocobalamin combination treatment and age-related macular degeneration in women: the Women's Antioxidant and Folic Acid Cardiovascular Study. Arch Intern Med (2009) 1.83
Evaluation of time domain and spectral domain optical coherence tomography in the measurement of diabetic macular edema. Invest Ophthalmol Vis Sci (2008) 1.83
Risk assessment model for development of advanced age-related macular degeneration. Arch Ophthalmol (2011) 1.75
Risk of advanced age-related macular degeneration after cataract surgery in the Age-Related Eye Disease Study: AREDS report 25. Ophthalmology (2008) 1.69
Lack of association between thiazolidinediones and macular edema in type 2 diabetes: the ACCORD eye substudy. Arch Ophthalmol (2010) 1.68
Tachyphylaxis after intravitreal bevacizumab for exudative age-related macular degeneration. Retina (2009) 1.67
Blindness and visual impairment: a public health issue for the future as well as today. Arch Ophthalmol (2004) 1.63
Low-dose aspirin and medical record-confirmed age-related macular degeneration in a randomized trial of women. Ophthalmology (2009) 1.62
National Eye Institute Visual Function Questionnaire in the Age-Related Eye Disease Study (AREDS): AREDS Report No. 10. Arch Ophthalmol (2003) 1.61
Optical coherence tomography measurements and analysis methods in optical coherence tomography studies of diabetic macular edema. Ophthalmology (2008) 1.60
Retinal precursors and the development of geographic atrophy in age-related macular degeneration. Ophthalmology (2007) 1.59
Report from the NEI/FDA Ophthalmic Clinical Trial Design and Endpoints Symposium. Invest Ophthalmol Vis Sci (2008) 1.58
Change in area of geographic atrophy in the Age-Related Eye Disease Study: AREDS report number 26. Arch Ophthalmol (2009) 1.53
Rationale for the diabetic retinopathy clinical research network treatment protocol for center-involved diabetic macular edema. Ophthalmology (2011) 1.52
Synergic effect of polymorphisms in ERCC6 5' flanking region and complement factor H on age-related macular degeneration predisposition. Proc Natl Acad Sci U S A (2006) 1.52
Prevalence of posterior subcapsular cataracts in volunteer cytapheresis donors. Transfusion (2010) 1.51
An electronic medical records system for clinical research and the EMR EDC interface. Invest Ophthalmol Vis Sci (2007) 1.48
Intravitreal anti-vascular endothelial growth factor therapy with pegaptanib for advanced von Hippel-Lindau disease of the retina. Retina (2007) 1.46
{omega}-3 Long-chain polyunsaturated fatty acid intake and 12-y incidence of neovascular age-related macular degeneration and central geographic atrophy: AREDS report 30, a prospective cohort study from the Age-Related Eye Disease Study. Am J Clin Nutr (2009) 1.44
Macular telangiectasia type 2. Prog Retin Eye Res (2012) 1.44
Costs of refractive correction of distance vision impairment in the United States, 1999-2002. Ophthalmology (2006) 1.43
Does long-term aspirin use increase the risk of neovascular age-related macular degeneration? Expert Opin Drug Saf (2014) 1.41
Vitamin E and the age-related eye disease study supplementation for age-related macular degeneration. Arch Ophthalmol (2005) 1.40
Identification of a rare coding variant in complement 3 associated with age-related macular degeneration. Nat Genet (2013) 1.39
Associations of mortality and diabetes complications in patients with type 1 and type 2 diabetes: early treatment diabetic retinopathy study report no. 27. Diabetes Care (2005) 1.34
Natural history of drusenoid pigment epithelial detachment in age-related macular degeneration: Age-Related Eye Disease Study Report No. 28. Ophthalmology (2010) 1.32
Lutein/zeaxanthin for the treatment of age-related cataract: AREDS2 randomized trial report no. 4. JAMA Ophthalmol (2013) 1.31
Relationship between photoreceptor outer segment length and visual acuity in diabetic macular edema. Retina (2010) 1.30
The long-term effects of laser photocoagulation treatment in patients with diabetic retinopathy: the early treatment diabetic retinopathy follow-up study. Ophthalmology (2003) 1.30
The prevalence of macular telangiectasia type 2 in the Beaver Dam eye study. Am J Ophthalmol (2010) 1.29
Heritability of the severity of diabetic retinopathy: the FIND-Eye study. Invest Ophthalmol Vis Sci (2008) 1.29
Hypomethylation of the IL17RC promoter associates with age-related macular degeneration. Cell Rep (2012) 1.28
Molecular pathology of eyes with von Hippel-Lindau (VHL) Disease: a review. Retina (2007) 1.25
The National Eye Institute Visual Function Questionnaire in the Macular Telangiectasia (MacTel) Project. Invest Ophthalmol Vis Sci (2008) 1.25
Clinical detection of precataractous lens protein changes using dynamic light scattering. Arch Ophthalmol (2008) 1.23
Mitochondrial DNA variants of respiratory complex I that uniquely characterize haplogroup T2 are associated with increased risk of age-related macular degeneration. PLoS One (2009) 1.19
Progression of geographic atrophy and genotype in age-related macular degeneration. Ophthalmology (2010) 1.18
Nutrient intake from food in children with autism. Pediatrics (2012) 1.18
The LOC387715 polymorphism and age-related macular degeneration: replication in three case-control samples. Invest Ophthalmol Vis Sci (2007) 1.17
Long-term effects of ranibizumab on diabetic retinopathy severity and progression. Arch Ophthalmol (2012) 1.16
Lutein and zeaxanthin protect photoreceptors from apoptosis induced by oxidative stress: relation with docosahexaenoic acid. Invest Ophthalmol Vis Sci (2007) 1.16
Baseline characteristics of participants in the natural history study of macular telangiectasia (MacTel) MacTel Project Report No. 2. Ophthalmic Epidemiol (2010) 1.14
Anatomical and visual results of vitreoretinal surgery for stage 5 retinopathy of prematurity. Retina (2006) 1.13