1
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Interleukin-10 determines viral clearance or persistence in vivo.
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Nat Med
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2006
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8.01
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2
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Myelomonocytic cell recruitment causes fatal CNS vascular injury during acute viral meningitis.
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Nature
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2008
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2.87
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3
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Intrinsic functional dysregulation of CD4 T cells occurs rapidly following persistent viral infection.
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2005
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2.75
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4
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Bone marrow plasmacytoid dendritic cells can differentiate into myeloid dendritic cells upon virus infection.
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Nat Immunol
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2.64
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5
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Viral persistence redirects CD4 T cell differentiation toward T follicular helper cells.
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J Exp Med
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2.48
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6
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IL-10 blockade facilitates DNA vaccine-induced T cell responses and enhances clearance of persistent virus infection.
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J Exp Med
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2008
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2.20
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7
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Viral targeting of hematopoietic progenitors and inhibition of DC maturation as a dual strategy for immune subversion.
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J Clin Invest
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2004
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Cross-linking cellular prion protein triggers neuronal apoptosis in vivo.
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9
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Generation of recombinant lymphocytic choriomeningitis viruses with trisegmented genomes stably expressing two additional genes of interest.
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Proc Natl Acad Sci U S A
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10
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Among CXCR3 chemokines, IFN-gamma-inducible protein of 10 kDa (CXC chemokine ligand (CXCL) 10) but not monokine induced by IFN-gamma (CXCL9) imprints a pattern for the subsequent development of autoimmune disease.
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J Immunol
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1.72
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11
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Reprogramming of antiviral T cells prevents inactivation and restores T cell activity during persistent viral infection.
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J Clin Invest
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1.59
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12
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A viral epitope that mimics a self antigen can accelerate but not initiate autoimmune diabetes.
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J Clin Invest
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2004
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1.51
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13
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PD-1 promotes immune exhaustion by inducing antiviral T cell motility paralysis.
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J Exp Med
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14
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Microglia development and function.
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Annu Rev Immunol
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1.41
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15
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Lymphocytic choriomeningitis infection of the central nervous system.
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1.21
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16
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Adoptive immunotherapy induces CNS dendritic cell recruitment and antigen presentation during clearance of a persistent viral infection.
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J Exp Med
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1.16
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17
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Visualizing the viral burden: phenotypic and functional alterations of T cells and APCs during persistent infection.
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J Immunol
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1.07
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18
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Migration of cytotoxic lymphocytes in cell cycle permits local MHC I-dependent control of division at sites of viral infection.
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J Exp Med
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1.03
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19
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Therapeutic memory T cells require costimulation for effective clearance of a persistent viral infection.
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J Virol
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2009
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0.97
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20
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Altered central nervous system gene expression caused by congenitally acquired persistent infection with lymphocytic choriomeningitis virus.
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J Virol
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Targeting tumor angiogenesis with adenovirus-delivered anti-Tie-2 intrabody.
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Direct comparison of demyelinating disease induced by the Daniel's strain and BeAn strain of Theiler's murine encephalomyelitis virus.
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Brain Pathol
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Therapeutic blockade of transforming growth factor beta fails to promote clearance of a persistent viral infection.
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In vivo dynamics of innate immune sentinels in the CNS.
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Intradiabodies, bispecific, tetravalent antibodies for the simultaneous functional knockout of two cell surface receptors.
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Type I interferon programs innate myeloid dynamics and gene expression in the virally infected nervous system.
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Microbial induction of vascular pathology in the CNS.
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J Neuroimmune Pharmacol
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The great balancing act: regulation and fate of antiviral T-cell interactions.
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Persistent viral infection elevates central nervous system MHC class I through chronic production of interferons.
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J Immunol
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30
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Cellular sources and targets of IFN-gamma-mediated protection against viral demyelination and neurological deficits.
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Eur J Immunol
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2002
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MRI confirms loss of blood-brain barrier integrity in a mouse model of disseminated candidiasis.
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Clearance of an immunosuppressive virus from the CNS coincides with immune reanimation and diversification.
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Virol J
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33
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Two-photon imaging of microbial immunity in living tissues.
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Microsc Microanal
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Inflammation on the mind: visualizing immunity in the central nervous system.
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Curr Top Microbiol Immunol
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2009
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A novel virus carrier state to evaluate immunotherapeutic regimens: regulatory T cells modulate the pathogenicity of antiviral memory cells.
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J Immunol
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Molecular anatomy and number of antigen specific CD8 T cells required to cause type 1 diabetes.
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