Published in Hum Mol Genet on August 01, 2012
Therapeutic benefit of lentiviral-mediated neonatal intracerebral gene therapy in a mouse model of globoid cell leukodystrophy. Hum Mol Genet (2014) 0.94
Combined gene/cell therapies provide long-term and pervasive rescue of multiple pathological symptoms in a murine model of globoid cell leukodystrophy. Hum Mol Genet (2015) 0.87
Missense mutation in mouse GALC mimics human gene defect and offers new insights into Krabbe disease. Hum Mol Genet (2013) 0.86
Region- and age-dependent alterations of glial-neuronal metabolic interactions correlate with CNS pathology in a mouse model of globoid cell leukodystrophy. J Cereb Blood Flow Metab (2013) 0.84
Neuroimmune mechanisms in Krabbe's disease. J Neurosci Res (2016) 0.80
Lysosomal Re-acidification Prevents Lysosphingolipid-Induced Lysosomal Impairment and Cellular Toxicity. PLoS Biol (2016) 0.79
MicroRNAs and Molecular Mechanisms of Neurodegeneration. Genes (Basel) (2013) 0.78
Two factor-based reprogramming of rodent and human fibroblasts into Schwann cells. Nat Commun (2017) 0.75
Metabolic profiling reveals biochemical pathways and potential biomarkers associated with the pathogenesis of Krabbe disease. J Neurosci Res (2016) 0.75
Pervasive supply of therapeutic lysosomal enzymes in the CNS of normal and Krabbe-affected non-human primates by intracerebral lentiviral gene therapy. EMBO Mol Med (2016) 0.75
Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma. Cancer Res (2004) 14.73
Genetic variant BDNF (Val66Met) polymorphism alters anxiety-related behavior. Science (2006) 5.89
Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy. Science (2013) 5.34
Injection of adult neurospheres induces recovery in a chronic model of multiple sclerosis. Nature (2003) 5.31
Melanoma contains CD133 and ABCG2 positive cells with enhanced tumourigenic potential. Eur J Cancer (2007) 3.80
Sortilin controls intracellular sorting of brain-derived neurotrophic factor to the regulated secretory pathway. J Neurosci (2005) 2.44
Site-specific integration and tailoring of cassette design for sustainable gene transfer. Nat Methods (2011) 2.30
Identification of hematopoietic stem cell-specific miRNAs enables gene therapy of globoid cell leukodystrophy. Sci Transl Med (2010) 1.84
Multipotent neural stem cells reside into the rostral extension and olfactory bulb of adult rodents. J Neurosci (2002) 1.81
Dissociation of the insulin receptor and caveolin-1 complex by ganglioside GM3 in the state of insulin resistance. Proc Natl Acad Sci U S A (2007) 1.79
Supernatant of aged erythrocytes causes lung inflammation and coagulopathy in a "two-hit" in vivo syngeneic transfusion model. Anesthesiology (2010) 1.72
Neural stem cells: an overview. Circ Res (2003) 1.64
N-glycolyl GM1 ganglioside as a receptor for simian virus 40. J Virol (2007) 1.59
Cardiolipin and monolysocardiolipin analysis in fibroblasts, lymphocytes, and tissues using high-performance liquid chromatography-mass spectrometry as a diagnostic test for Barth syndrome. Anal Biochem (2009) 1.56
Tumor-mediated liver X receptor-alpha activation inhibits CC chemokine receptor-7 expression on dendritic cells and dampens antitumor responses. Nat Med (2009) 1.54
Cardiac and skeletal muscle defects in a mouse model of human Barth syndrome. J Biol Chem (2010) 1.54
Efficient in vitro labeling of human neural precursor cells with superparamagnetic iron oxide particles: relevance for in vivo cell tracking. Stem Cells (2007) 1.53
Notch signaling in astrocytes and neuroblasts of the adult subventricular zone in health and after cortical injury. Dev Neurosci (2006) 1.48
Brain regeneration in physiology and pathology: the immune signature driving therapeutic plasticity of neural stem cells. Physiol Rev (2011) 1.40
Robust in vivo gene transfer into adult mammalian neural stem cells by lentiviral vectors. Proc Natl Acad Sci U S A (2004) 1.40
The enigmatic role of tafazzin in cardiolipin metabolism. Biochim Biophys Acta (2009) 1.35
Human neural stem cells ameliorate autoimmune encephalomyelitis in non-human primates. Ann Neurol (2009) 1.30
Chain formation and glial tube assembly in the shift from neonatal to adult subventricular zone of the rodent forebrain. J Comp Neurol (2005) 1.29
Cell cycle and lineage progression of neural progenitors in the ventricular-subventricular zones of adult mice. Proc Natl Acad Sci U S A (2013) 1.28
A novel endocytic recycling signal distinguishes biological responses of Trk neurotrophin receptors. Mol Biol Cell (2005) 1.27
Emx2 regulates the proliferation of stem cells of the adult mammalian central nervous system. Development (2002) 1.24
Neural stem cell gene therapy ameliorates pathology and function in a mouse model of globoid cell leukodystrophy. Stem Cells (2011) 1.22
Met signals hepatocyte survival by preventing Fas-triggered FLIP degradation in a PI3k-Akt-dependent manner. Hepatology (2007) 1.21
The plasma membrane-associated sialidase MmNEU3 modifies the ganglioside pattern of adjacent cells supporting its involvement in cell-to-cell interactions. J Biol Chem (2004) 1.19
Ceramide and sphingomyelin species of fibroblasts and neurons in culture. J Lipid Res (2006) 1.19
Identification and characterization of human cardiolipin synthase. FEBS Lett (2006) 1.17
Cellular composition and cytoarchitecture of the rabbit subventricular zone and its extensions in the forebrain. J Comp Neurol (2006) 1.13
Glycosphingolipid behaviour in complex membranes. Biochim Biophys Acta (2008) 1.10
DCX and PSA-NCAM expression identifies a population of neurons preferentially distributed in associative areas of different pallial derivatives and vertebrate species. Cereb Cortex (2008) 1.08
Characterization of carnitine and fatty acid metabolism in the long-chain acyl-CoA dehydrogenase-deficient mouse. Biochem J (2005) 1.08
beta-Ureidopropionase deficiency: an inborn error of pyrimidine degradation associated with neurological abnormalities. Hum Mol Genet (2004) 1.08
A phospholipidomic analysis of all defined human plasma lipoproteins. Sci Rep (2011) 1.07
Peroxisomal alterations in Alzheimer's disease. Acta Neuropathol (2011) 1.06
Lipid-based nanoparticles with high binding affinity for amyloid-beta1-42 peptide. Biomaterials (2010) 1.06
The oxysterol-CXCR2 axis plays a key role in the recruitment of tumor-promoting neutrophils. J Exp Med (2013) 1.06
Identification of the fenretinide metabolite 4-oxo-fenretinide present in human plasma and formed in human ovarian carcinoma cells through induction of cytochrome P450 26A1. Clin Cancer Res (2004) 1.06
Widespread enzymatic correction of CNS tissues by a single intracerebral injection of therapeutic lentiviral vector in leukodystrophy mouse models. Hum Mol Genet (2010) 1.02
A subpial, transitory germinal zone forms chains of neuronal precursors in the rabbit cerebellum. Dev Biol (2006) 1.01
Genesis of neuronal and glial progenitors in the cerebellar cortex of peripuberal and adult rabbits. PLoS One (2008) 0.99
Molecular characterization of iodotyrosine dehalogenase deficiency in patients with hypothyroidism. J Clin Endocrinol Metab (2008) 0.99
Defective postnatal neurogenesis and disorganization of the rostral migratory stream in absence of the Vax1 homeobox gene. J Neurosci (2004) 0.98
Involvement of very long fatty acid-containing lactosylceramide in lactosylceramide-mediated superoxide generation and migration in neutrophils. Glycoconj J (2007) 0.98
Nitric oxide boosts chemoimmunotherapy via inhibition of acid sphingomyelinase in a mouse model of melanoma. Cancer Res (2007) 0.98
Brain pathology in Niemann Pick disease type A: insights from the acid sphingomyelinase knockout mice. J Neurochem (2011) 0.97
Dynamics of membrane lipid domains in neuronal cells differentiated in culture. J Lipid Res (2003) 0.97
Human neural crest-derived postnatal cells exhibit remarkable embryonic attributes either in vitro or in vivo. Eur Cell Mater (2011) 0.97
GM3 synthase overexpression results in reduced cell motility and in caveolin-1 upregulation in human ovarian carcinoma cells. Glycobiology (2009) 0.96
Cell surface associated glycohydrolases in normal and Gaucher disease fibroblasts. J Inherit Metab Dis (2012) 0.95
Gangliosides and the multiscale modulation of membrane structure. Chem Phys Lipids (2011) 0.95
Saposin B binds and transfers phospholipids. J Lipid Res (2006) 0.94
Specific determination of beta-galactocerebrosidase activity via competitive inhibition of beta-galactosidase. Clin Chem (2009) 0.93
Lentiviral vector gene transfer is limited by the proteasome at postentry steps in various types of stem cells. Stem Cells (2008) 0.93
Lack of ceramide generation and altered sphingolipid composition are associated with drug resistance in human ovarian carcinoma cells. Biochem J (2006) 0.92
Lyn-coupled LacCer-enriched lipid rafts are required for CD11b/CD18-mediated neutrophil phagocytosis of nonopsonized microorganisms. J Leukoc Biol (2007) 0.92
Sphingolipid uptake by cultured cells: complex aggregates of cell sphingolipids with serum proteins and lipoproteins are rapidly catabolized. J Biol Chem (2004) 0.92
Deregulated sphingolipid metabolism and membrane organization in neurodegenerative disorders. Mol Neurobiol (2010) 0.92
Thin layer chromatography of gangliosides. Glycoconj J (2009) 0.91
Sphingosine kinase mediates resistance to the synthetic retinoid N-(4-hydroxyphenyl)retinamide in human ovarian cancer cells. J Biol Chem (2010) 0.91
Effects of developmental age, brain region, and time in culture on long-term proliferation and multipotency of neural stem cell populations. J Comp Neurol (2009) 0.90
Lipid content of brain, brain membrane lipid domains, and neurons from acid sphingomyelinase deficient mice. J Neurochem (2008) 0.90
Altered sphingolipid metabolism in N-(4-hydroxyphenyl)-retinamide-resistant A2780 human ovarian carcinoma cells. J Biol Chem (2002) 0.90
Selected natural and synthetic retinoids impair CCR7- and CXCR4-dependent cell migration in vitro and in vivo. J Leukoc Biol (2008) 0.89
Detection of nonsterol isoprenoids by HPLC-MS/MS. Anal Biochem (2008) 0.89
Plasma membrane production of ceramide from ganglioside GM3 in human fibroblasts. FASEB J (2006) 0.89
Method for measurement of peroxisomal very-long-chain fatty acid beta-oxidation in human skin fibroblasts using stable-isotope-labeled tetracosanoic acid. Clin Chem (2004) 0.88
Unique expression and localization of aquaporin-4 and aquaporin-9 in murine and human neural stem cells and in their glial progeny. Glia (2006) 0.88
Arginine and mixed amino acids increase protein accretion in the growth-restricted and normal ovine fetus by different mechanisms. Pediatr Res (2005) 0.88
Barth syndrome in a female patient. Mol Genet Metab (2012) 0.88
A glycosphingolipid/caveolin-1 signaling complex inhibits motility of human ovarian carcinoma cells. J Biol Chem (2011) 0.87
Quantification of 5,6-dihydrouracil by HPLC-electrospray tandem mass spectrometry. Clin Chem (2004) 0.87
PSI1 is responsible for the stearic acid enrichment that is characteristic of phosphatidylinositol in yeast. FEBS J (2009) 0.87
Towards a comparative understanding of adult neurogenesis. Eur J Neurosci (2011) 0.87
Characterization of D-3-hydroxybutyrylcarnitine (ketocarnitine): an identified ketosis-induced metabolite. Metabolism (2011) 0.87
Tuning multi/pluri-potent stem cell fate by electrospun poly(L-lactic acid)-calcium-deficient hydroxyapatite nanocomposite mats. Biomacromolecules (2012) 0.87
Solid phase immunoadsorption for therapeutic and analytical studies on neuropathy-associated anti-GM1 antibodies. Glycobiology (2006) 0.86
Cholestasis is associated with hepatic microvascular dysfunction and aberrant energy metabolism before and during ischemia-reperfusion. Antioxid Redox Signal (2012) 0.86
Robust generation of oligodendrocyte progenitors from human neural stem cells and engraftment in experimental demyelination models in mice. PLoS One (2010) 0.85
Sphingolipidomics of A2780 human ovarian carcinoma cells treated with synthetic retinoids. J Lipid Res (2010) 0.85
Neural precursor cell cultures from GM2 gangliosidosis animal models recapitulate the biochemical and molecular hallmarks of the brain pathology. J Neurochem (2009) 0.85