Investigating metabotropic glutamate receptor 5 allosteric modulator cooperativity, affinity, and agonism: enriching structure-function studies and structure-activity relationships.

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Published in Mol Pharmacol on August 03, 2012

Authors

Karen J Gregory1, Meredith J Noetzel, Jerri M Rook, Paige N Vinson, Shaun R Stauffer, Alice L Rodriguez, Kyle A Emmitte, Ya Zhou, Aspen C Chun, Andrew S Felts, Brian A Chauder, Craig W Lindsley, Colleen M Niswender, P Jeffrey Conn

Author Affiliations

1: Department of Pharmacology, Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt University Medical Center, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA.

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